PL2254887T3 - Pochodne oksazolidynonu - Google Patents

Pochodne oksazolidynonu

Info

Publication number
PL2254887T3
PL2254887T3 PL09711588T PL09711588T PL2254887T3 PL 2254887 T3 PL2254887 T3 PL 2254887T3 PL 09711588 T PL09711588 T PL 09711588T PL 09711588 T PL09711588 T PL 09711588T PL 2254887 T3 PL2254887 T3 PL 2254887T3
Authority
PL
Poland
Prior art keywords
oxazolidinone derivatives
oxazolidinone
derivatives
Prior art date
Application number
PL09711588T
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Acklin Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of PL2254887T3 publication Critical patent/PL2254887T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL09711588T 2008-02-22 2009-02-20 Pochodne oksazolidynonu PL2254887T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IB2008050651 2008-02-22
IB2008054095 2008-10-07
EP09711588.5A EP2254887B9 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives
PCT/IB2009/050702 WO2009104159A1 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives

Publications (1)

Publication Number Publication Date
PL2254887T3 true PL2254887T3 (pl) 2013-05-31

Family

ID=40578768

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09711588T PL2254887T3 (pl) 2008-02-22 2009-02-20 Pochodne oksazolidynonu

Country Status (14)

Country Link
US (1) US8349826B2 (pl)
EP (1) EP2254887B9 (pl)
JP (1) JP5404652B2 (pl)
KR (1) KR101592046B1 (pl)
CN (1) CN102015698B (pl)
AR (1) AR070458A1 (pl)
BR (1) BRPI0908208A2 (pl)
CA (1) CA2713187C (pl)
ES (1) ES2398939T3 (pl)
MX (1) MX2010008921A (pl)
PL (1) PL2254887T3 (pl)
RU (1) RU2501799C2 (pl)
TW (1) TWI429643B (pl)
WO (1) WO2009104159A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
BRPI0920895A8 (pt) 2008-10-07 2017-12-26 Actelion Pharmaceuticals Ltd Compostos antibióticos de oxazolidinona tricíclica
WO2010041219A1 (en) * 2008-10-10 2010-04-15 Actelion Pharmaceuticals Ltd 2-benzothiophenyl-and 2-naphthyl-0xaz0lidin0nes and their azaisostere analogues as antibacterial agents
KR101667066B1 (ko) * 2008-10-10 2016-10-17 액테리온 파마슈티칼 리미티드 옥사졸리디닐 항생제
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
TW201309689A (zh) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd 含胺基之吡咯啶酮衍生物
CA2842885A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
IN2014CN04126A (pl) * 2011-11-08 2015-07-10 Actelion Pharmaceuticals Ltd
CA2854266A1 (en) 2011-11-30 2013-06-06 Actelion Pharmaceuticals Ltd 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
JP2016504408A (ja) 2013-01-09 2016-02-12 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 抗菌活性を有するオキサジアゾロン誘導体
PL2986607T3 (pl) 2013-04-16 2017-11-30 Idorsia Pharmaceuticals Ltd Przeciwbakteryjne pochodne biaromatyczne
WO2014181266A1 (en) 2013-05-08 2014-11-13 Actelion Pharmaceuticals Ltd Antibacterial phthalide derivatives
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
WO2017137743A1 (en) * 2016-02-08 2017-08-17 Redx Pharma Plc Antibacterial compounds
EA201891654A1 (ru) * 2016-02-08 2019-01-31 РЭДКС ФАРМА ПиЭлСи Антибактериальные соединения
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
PL3634968T3 (pl) * 2017-06-08 2023-07-31 Bugworks Research, Inc. Związki heterocykliczne użyteczne jako środki przeciwbakteryjne oraz sposób ich wytwarzania
WO2019106693A1 (en) * 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
EP3774790B1 (en) * 2018-03-28 2023-01-25 Bugworks Research, Inc. Oxazolidinone antibiotic compounds and process of preparation

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
GB2168696B (en) 1984-12-21 1989-01-11 Boehringer Biochemia Srl Fluoro coumarins as antilymphoedema agents
CA2012681A1 (en) * 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
CN1163892A (zh) * 1996-01-16 1997-11-05 拜尔公司 2-氧代-和2-硫代-1,2-二氢喹啉基-噁唑烷酮类化合物
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
AU1026901A (en) 1999-10-29 2001-05-08 Syngenta Participations Ag Novel herbicides
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
AU2004299278C9 (en) * 2003-12-18 2013-10-24 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
EP1771456A2 (fr) * 2004-07-30 2007-04-11 Palumed SA Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
ATE465163T1 (de) 2005-12-22 2010-05-15 Glaxo Group Ltd Heterocyclische verbindungen, ihre herstellung und ihre verwendung als antibakterielle mittel
US20090318431A1 (en) * 2006-02-14 2009-12-24 Pfizer Inc. Benzoxazinone and benzoxazepinone oxazolidinones as antibacterial agents
CN101454319B (zh) 2006-05-26 2012-06-27 富山化学工业株式会社 新杂环化合物或其盐及其中间体
HRP20110845T1 (hr) 2006-06-16 2011-12-31 Pharma Mar Antitumorski dihidropiran-2-onski spojevi
JP2010511018A (ja) 2006-12-01 2010-04-08 ガラパゴス・ナムローゼ・フェンノートシャップ 変性疾患及び炎症性疾患の治療に有用なトリアゾロピリジン化合物
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.

Also Published As

Publication number Publication date
EP2254887B1 (en) 2012-12-19
EP2254887A1 (en) 2010-12-01
EP2254887B9 (en) 2013-05-29
RU2010138840A (ru) 2012-03-27
ES2398939T9 (es) 2013-07-24
KR101592046B1 (ko) 2016-02-05
BRPI0908208A2 (pt) 2015-08-25
CA2713187A1 (en) 2009-08-27
ES2398939T3 (es) 2013-03-22
JP5404652B2 (ja) 2014-02-05
AU2009215247A1 (en) 2009-08-27
MX2010008921A (es) 2010-09-07
TW200940534A (en) 2009-10-01
US20100331308A1 (en) 2010-12-30
CA2713187C (en) 2016-06-07
JP2011512401A (ja) 2011-04-21
CN102015698B (zh) 2014-08-27
TWI429643B (zh) 2014-03-11
RU2501799C2 (ru) 2013-12-20
WO2009104159A1 (en) 2009-08-27
AR070458A1 (es) 2010-04-07
US8349826B2 (en) 2013-01-08
CN102015698A (zh) 2011-04-13
KR20100124282A (ko) 2010-11-26

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