PL2268612T3 - Arylosulfonamidowe inhibitory metaloproteinaz macierzy - Google Patents

Arylosulfonamidowe inhibitory metaloproteinaz macierzy

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Publication number
PL2268612T3
PL2268612T3 PL09724483T PL09724483T PL2268612T3 PL 2268612 T3 PL2268612 T3 PL 2268612T3 PL 09724483 T PL09724483 T PL 09724483T PL 09724483 T PL09724483 T PL 09724483T PL 2268612 T3 PL2268612 T3 PL 2268612T3
Authority
PL
Poland
Prior art keywords
arylsulfonamide
based matrix
matrix metalloprotease
metalloprotease inhibitors
inhibitors
Prior art date
Application number
PL09724483T
Other languages
English (en)
Inventor
Claus Ehrhardt
Leslie Wighton Mcquire
Pascal Rigollier
Olivier Rogel
Michael Shultz
Ruben Alberto Tommasi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2268612T3 publication Critical patent/PL2268612T3/pl

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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
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CN102036953A (zh) 2011-04-27
US20150045398A1 (en) 2015-02-12
KR101673621B1 (ko) 2016-11-07
JP5490092B2 (ja) 2014-05-14
EP2268612A1 (en) 2011-01-05
PT2268612E (pt) 2014-11-13
ES2524259T3 (es) 2014-12-04
US9822092B2 (en) 2017-11-21
US20130096105A1 (en) 2013-04-18
EA020114B1 (ru) 2014-08-29
US8222424B2 (en) 2012-07-17
KR20100127291A (ko) 2010-12-03
CA2719457C (en) 2017-05-02
MX2010010525A (es) 2010-10-25
US8362063B2 (en) 2013-01-29
BRPI0908603A2 (pt) 2020-08-18
US20110014186A1 (en) 2011-01-20
US8975439B2 (en) 2015-03-10
EA201001523A1 (ru) 2011-06-30
CN102036953B (zh) 2015-05-06
US20120258954A1 (en) 2012-10-11
EP2268612B1 (en) 2014-08-20
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