PL2268644T3 - Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania - Google Patents

Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania

Info

Publication number
PL2268644T3
PL2268644T3 PL09716535T PL09716535T PL2268644T3 PL 2268644 T3 PL2268644 T3 PL 2268644T3 PL 09716535 T PL09716535 T PL 09716535T PL 09716535 T PL09716535 T PL 09716535T PL 2268644 T3 PL2268644 T3 PL 2268644T3
Authority
PL
Poland
Prior art keywords
compounds
preparation
pyridine derivatives
medicaments containing
tricyclic pyridine
Prior art date
Application number
PL09716535T
Other languages
English (en)
Inventor
Holger Wagner
Daniela Berta
Riccardo Giovannini
Alessandro Mazzacani
Ruediger Streicher
Klaus Fuchs
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PL2268644T3 publication Critical patent/PL2268644T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL09716535T 2008-03-05 2009-03-02 Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania PL2268644T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08152288 2008-03-05
EP08161366 2008-07-29
PCT/EP2009/052459 WO2009109549A1 (en) 2008-03-05 2009-03-02 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
EP09716535A EP2268644B1 (en) 2008-03-05 2009-03-02 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation

Publications (1)

Publication Number Publication Date
PL2268644T3 true PL2268644T3 (pl) 2012-01-31

Family

ID=40548681

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09716535T PL2268644T3 (pl) 2008-03-05 2009-03-02 Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania

Country Status (21)

Country Link
US (1) US8703793B2 (pl)
EP (1) EP2268644B1 (pl)
JP (1) JP5291126B2 (pl)
KR (1) KR20100122089A (pl)
CN (1) CN102015722A (pl)
AR (1) AR070788A1 (pl)
AT (1) ATE520696T1 (pl)
AU (1) AU2009221179A1 (pl)
BR (1) BRPI0909105A2 (pl)
CA (1) CA2717013A1 (pl)
CL (1) CL2009000510A1 (pl)
DK (1) DK2268644T3 (pl)
ES (1) ES2372012T3 (pl)
IL (1) IL207263A0 (pl)
MX (1) MX2010009607A (pl)
NZ (1) NZ587748A (pl)
PL (1) PL2268644T3 (pl)
RU (1) RU2010140442A (pl)
TW (1) TW200942547A (pl)
WO (1) WO2009109549A1 (pl)
ZA (1) ZA201005315B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2268644B1 (en) 2008-03-05 2011-08-17 Boehringer Ingelheim International GmbH Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
MX2012009149A (es) * 2010-02-19 2012-09-28 Boehringer Ingelheim Int Derivados de piridina triciclicos, medicamentos que contienen tales compuestos, su uso y proceso para su preparacion.
CA2804924C (en) 2010-07-09 2016-06-28 Daiichi Sankyo Company, Limited Substituted pyridine compound
JP2014506887A (ja) * 2011-02-17 2014-03-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 三環式ピリジン誘導体、このような化合物を含有する医薬、それらの使用およびそれらの調製のためのプロセス
US9150583B2 (en) 2011-08-17 2015-10-06 Boehringer Ingelheim International Gmbh Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation
WO2013024149A1 (en) * 2011-08-18 2013-02-21 Boehringer Ingelheim International Gmbh Crystalline forms of octahydro-3h-spiro [furo [3, 4-c] quinoline -1, 4 '-pyran] -9-ol
WO2013103150A1 (ja) 2012-01-06 2013-07-11 第一三共株式会社 置換ピリジン化合物の酸付加塩
CN110950881A (zh) * 2018-09-27 2020-04-03 中国科学院上海药物研究所 一类三环类似物、其制备方法和用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798619A (en) 1980-06-02 1989-01-17 American Cyanamid Co. 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents
KR900701792A (ko) * 1988-08-16 1990-12-04 로버어트 에이 아미테이지 Acat 효소를 차단하는데 효과적인 이가 리간드
ATE221520T1 (de) 1995-09-29 2002-08-15 Glaxo Wellcome Spa Tetrahydrochinoline als nmda antagonisten
DE19627431A1 (de) 1996-07-08 1998-01-15 Bayer Ag Heterocyclisch kondensierte Pyridine
HRP970330B1 (en) * 1996-07-08 2004-06-30 Bayer Ag Cycloalkano pyridines
EP1009741A1 (de) 1997-09-04 2000-06-21 Basf Aktiengesellschaft Neue carbonsäurederivate, ihre herstellung und verwendung als gemischte et a?/et b?-endothelin-rezeptorantagonisten
MA24643A1 (fr) * 1997-09-18 1999-04-01 Bayer Ag Tetrahydro-naphtalenes substitues et composes analogues
DE19741051A1 (de) 1997-09-18 1999-03-25 Bayer Ag Hetero-Tetrahydrochinoline
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
DE10148436A1 (de) * 2001-10-01 2003-04-17 Bayer Ag Tetrahydrochinoline
PE20060653A1 (es) 2004-08-31 2006-09-27 Glaxo Group Ltd Derivados triciclicos condensados como moduladores del receptor 5-ht1
DE102004060997A1 (de) * 2004-12-18 2006-06-22 Bayer Healthcare Ag Chemische Verbindung und ihre Verwendung
BRPI0519602A2 (pt) 2004-12-18 2009-02-25 Bayer Healthcare Ag derivados de tetrahidroquinolina substituÍdos com 4-cicloalquila e seu uso como medicamento
KR20070090192A (ko) 2004-12-18 2007-09-05 바이엘 헬스케어 아게 (5ｓ)-3-[(ｓ)-플루오로(4-트리플루오로메틸페닐)메틸]-5,6,7,8-테트라히드로퀴놀린-5-올 유도체 및 이의 ｃｅｔｐ억제제로서의 용도
EP2268644B1 (en) 2008-03-05 2011-08-17 Boehringer Ingelheim International GmbH Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
MX2012009149A (es) 2010-02-19 2012-09-28 Boehringer Ingelheim Int Derivados de piridina triciclicos, medicamentos que contienen tales compuestos, su uso y proceso para su preparacion.
JP2014506887A (ja) 2011-02-17 2014-03-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 三環式ピリジン誘導体、このような化合物を含有する医薬、それらの使用およびそれらの調製のためのプロセス
US9150583B2 (en) 2011-08-17 2015-10-06 Boehringer Ingelheim International Gmbh Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation
WO2013024149A1 (en) 2011-08-18 2013-02-21 Boehringer Ingelheim International Gmbh Crystalline forms of octahydro-3h-spiro [furo [3, 4-c] quinoline -1, 4 '-pyran] -9-ol

Also Published As

Publication number Publication date
JP5291126B2 (ja) 2013-09-18
CL2009000510A1 (es) 2010-04-09
ES2372012T3 (es) 2012-01-12
DK2268644T3 (da) 2011-10-10
AU2009221179A1 (en) 2009-09-11
CN102015722A (zh) 2011-04-13
WO2009109549A1 (en) 2009-09-11
EP2268644B1 (en) 2011-08-17
BRPI0909105A2 (pt) 2015-08-25
US20110021550A1 (en) 2011-01-27
TW200942547A (en) 2009-10-16
MX2010009607A (es) 2010-09-30
AR070788A1 (es) 2010-05-05
RU2010140442A (ru) 2012-04-10
ZA201005315B (en) 2011-03-30
IL207263A0 (en) 2010-12-30
NZ587748A (en) 2012-01-12
KR20100122089A (ko) 2010-11-19
ATE520696T1 (de) 2011-09-15
EP2268644A1 (en) 2011-01-05
JP2011513361A (ja) 2011-04-28
CA2717013A1 (en) 2009-09-11
US8703793B2 (en) 2014-04-22

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