PL2274303T3 - Sposoby otrzymywania sunitynibu i jego soli - Google Patents

Sposoby otrzymywania sunitynibu i jego soli

Info

Publication number: PL2274303T3
Authority: PL; Poland
Prior art keywords: salts; processes; preparing sunitinib; sunitinib; preparing
Prior art date: 2008-03-31

Application number

PL09728114T

Other languages

English (en)

Inventor

Ettore Bigatti

Augusto Canavesi

Peter Lindsay Macdonald

Francesca Scarpitta

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-31

Filing date

2009-03-31

Publication date

2013-03-29

2009-03-31 Application filed by Teva Pharma filed Critical Teva Pharma

2013-03-29 Publication of PL2274303T3 publication Critical patent/PL2274303T3/pl

Links

239000002147 L01XE04 - Sunitinib Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
WINHZLLDWRZWRT-ATVHPVEESA-N sunitinib Chemical compound CCN(CC)CCNC(=O)C1=C(C)NC(\C=C/2C3=CC(F)=CC=C3NC\2=O)=C1C WINHZLLDWRZWRT-ATVHPVEESA-N 0.000 title 1
229960001796 sunitinib Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL09728114T 2008-03-31 2009-03-31 Sposoby otrzymywania sunitynibu i jego soli PL2274303T3 (pl)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
US4110308P	2008-03-31	2008-03-31
US8240508P	2008-07-21	2008-07-21
US8268108P	2008-07-22	2008-07-22
US8899808P	2008-08-14	2008-08-14
US9434108P	2008-09-04	2008-09-04
US9759208P	2008-09-17	2008-09-17
US11304408P	2008-11-10	2008-11-10
EP09728114A EP2274303B1 (en)	2008-03-31	2009-03-31	Processes for preparing sunitinib and salts thereof
PCT/US2009/038934 WO2009124037A1 (en)	2008-03-31	2009-03-31	Processes for preparing sunitinib and salts thereof

Publications (1)

Publication Number	Publication Date
PL2274303T3 true PL2274303T3 (pl)	2013-03-29

Family

ID=40791224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL09728114T PL2274303T3 (pl)	2008-03-31	2009-03-31	Sposoby otrzymywania sunitynibu i jego soli

Country Status (8)

Country	Link
US (2)	US20090247767A1 (pl)
EP (1)	EP2274303B1 (pl)
JP (1)	JP2011516488A (pl)
KR (1)	KR20100119582A (pl)
CA (1)	CA2720164A1 (pl)
ES (1)	ES2391501T3 (pl)
PL (1)	PL2274303T3 (pl)
WO (1)	WO2009124037A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009128083A1 (en) *	2008-04-16	2009-10-22	Natco Pharma Limited	Novel polymorphic forms of sunitinib base
AU2010363613B2 (en)	2010-11-01	2015-02-05	Scinopharm (Kunshan) Biochemical Technology Co., Ltd.	Processes for the preparation of 3-((pyrrol-2-yl)methylene)-2-pyrrolones using 2-silyloxy-pyrroles
CN104114550A (zh) *	2012-03-23	2014-10-22	劳拉斯实验室私人有限公司	制备舒尼替尼及其酸加成盐的改进的方法
US11136625B2 (en)	2013-08-28	2021-10-05	Crown Bioscience, Inc. (Taicang)	Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same
CN105622680B (zh) *	2015-12-22	2018-01-19	杭州卢普生物科技有限公司	一种舒尼替尼衍生物及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20020751B1 (hr) *	2000-02-15	2011-01-31	Sugen	Pirolom supstituirani 2-indolinoni kao inhibitori protein kinaze
DE10023484A1 (de) *	2000-05-09	2001-11-22	Schering Ag	Anthranylamide und deren Verwendung als Arzneimittel
AR042586A1 (es) *	2001-02-15	2005-06-29	Sugen Inc	3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
SI1419151T1 (sl) *	2001-08-15	2014-04-30	Pharmacia & Upjohn Company Llc	Kristali, ki vključujejo sol jabolčne kisline N-(2-(dietilamino)etil)-5-((5-fluoro-1,2-dihidro-2-okso-3H-indol-3- iliden)metil)-2,4-dimetil-1H-pirol-3-karboksamida, postopki za njihovo pripravo in sestavki le-teh
JP2005508953A (ja) *	2001-10-10	2005-04-07	スージェン・インコーポレーテッド	キナーゼ阻害剤としての３−［４−（置換ヘテロサイクリル）−ピロール−２−イルメチリデン］−２−インドリノン誘導体
JP2005528344A (ja) *	2002-02-15	2005-09-22	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	インドリノン誘導体の製造法
ES2197003B1 (es) *	2002-04-08	2005-03-16	J. URIACH & CIA S.A.	Nuevos compuestos antagonistas de integrinas alfa.
CN100343237C (zh) *	2002-06-28	2007-10-17	日本新药株式会社	酰胺衍生物及医药品
US7427611B2 (en) *	2003-09-26	2008-09-23	Solvay Pharmaceuticals Gmbh	Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US20060009510A1 (en) *	2004-07-09	2006-01-12	Pharmacia & Upjohn Company Llc	Method of synthesizing indolinone compounds
PT1773768T (pt) *	2004-07-30	2018-11-30	Exelixis Inc	Derivados de pirrol como agentes farmacêuticos
JP5123668B2 (ja) *	2005-01-10	2013-01-23	エグゼリクシス，インコーポレイテッド	医薬品としての複素環カルボキサミド化合物
CN101389331A (zh) *	2005-12-29	2009-03-18	斯克里普斯研究学院	基于吲哚满酮的氨基酸衍生物的蛋白激酶抑制剂
WO2009067686A2 (en) *	2007-11-21	2009-05-28	Teva Pharmaceutical Industries Ltd.	Sunitinib hemi-l-malate, polymorphs and preparation thereof, polymorphs of racemic sunitinib malate, compositins containing sunitinib base and malic acid and preparation thereof

2009
- 2009-03-31 CA CA2720164A patent/CA2720164A1/en not_active Abandoned
- 2009-03-31 EP EP09728114A patent/EP2274303B1/en not_active Not-in-force
- 2009-03-31 PL PL09728114T patent/PL2274303T3/pl unknown
- 2009-03-31 JP JP2011503093A patent/JP2011516488A/ja active Pending
- 2009-03-31 ES ES09728114T patent/ES2391501T3/es active Active
- 2009-03-31 US US12/415,352 patent/US20090247767A1/en not_active Abandoned
- 2009-03-31 WO PCT/US2009/038934 patent/WO2009124037A1/en not_active Ceased
- 2009-03-31 KR KR1020107021937A patent/KR20100119582A/ko not_active Ceased
2010
- 2010-03-04 US US12/717,481 patent/US20100160646A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2274303A1 (en)	2011-01-19
US20100160646A1 (en)	2010-06-24
JP2011516488A (ja)	2011-05-26
ES2391501T3 (es)	2012-11-27
EP2274303B1 (en)	2012-08-29
WO2009124037A1 (en)	2009-10-08
US20090247767A1 (en)	2009-10-01
CA2720164A1 (en)	2009-10-08
KR20100119582A (ko)	2010-11-09

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