PL2292611T3 - Nowa pochodna tiofenodiaminy mająca strukturę mocznikową - Google Patents

Nowa pochodna tiofenodiaminy mająca strukturę mocznikową

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Publication number
PL2292611T3
PL2292611T3 PL09750683T PL09750683T PL2292611T3 PL 2292611 T3 PL2292611 T3 PL 2292611T3 PL 09750683 T PL09750683 T PL 09750683T PL 09750683 T PL09750683 T PL 09750683T PL 2292611 T3 PL2292611 T3 PL 2292611T3
Authority
PL
Poland
Prior art keywords
urea structure
novel
derivative
thiophenediamine derivative
novel thiophenediamine
Prior art date
Application number
PL09750683T
Other languages
English (en)
Inventor
Hiroyuki Mogi
Hisashi Tajima
Noriko Mishina
Yusuke Yamazaki
Shinji Yoneda
Katsuhiko Watanabe
Junko Fujikawa
Minoru Yamamoto
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of PL2292611T3 publication Critical patent/PL2292611T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
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  • Pain & Pain Management (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
PL09750683T 2008-05-23 2009-05-25 Nowa pochodna tiofenodiaminy mająca strukturę mocznikową PL2292611T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008134902 2008-05-23
PCT/JP2009/059494 WO2009142321A1 (ja) 2008-05-23 2009-05-25 ウレア構造を有する新規チオフェンジアミン誘導体
EP09750683A EP2292611B1 (en) 2008-05-23 2009-05-25 Novel thiophenediamine derivative having urea structure

Publications (1)

Publication Number Publication Date
PL2292611T3 true PL2292611T3 (pl) 2012-11-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL09750683T PL2292611T3 (pl) 2008-05-23 2009-05-25 Nowa pochodna tiofenodiaminy mająca strukturę mocznikową

Country Status (9)

Country Link
US (2) US8198271B2 (pl)
EP (1) EP2292611B1 (pl)
JP (1) JP2010001289A (pl)
KR (1) KR20110028262A (pl)
CN (1) CN102036978A (pl)
CA (1) CA2724357A1 (pl)
ES (1) ES2389754T3 (pl)
PL (1) PL2292611T3 (pl)
WO (1) WO2009142321A1 (pl)

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CN106977443A (zh) * 2017-04-24 2017-07-25 南昌大学 一类o‑苄基取代的异羟肟酸衍生物及其制备方法和药物的用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005723A1 (fr) 1988-11-24 1990-05-31 Yoshitomi Pharmaceutical Industries, Ltd. Composes de trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane et leur utilisation en medecine
US5798380A (en) 1996-02-21 1998-08-25 Wisconsin Alumni Research Foundation Cytoskeletal active agents for glaucoma therapy
KR100616466B1 (ko) * 1998-08-17 2006-08-29 센주 세이야꾸 가부시키가이샤 녹내장 예방/치료제
CA2465978C (en) * 2001-09-14 2015-04-07 Soon Hyung Woo Inhibitors of histone deacetylase
US20040092431A1 (en) * 2002-11-12 2004-05-13 Hellberg Peggy E. Histone deacetylase inhibitors for treating degenerative diseases of the eye
TW200426138A (en) * 2002-12-10 2004-12-01 Hoffmann La Roche Novel arylene-carboxylic acid (2-amino-phenyl)-amide derivatives, their manufacture and use as pharmaceutical agents
JP4612621B2 (ja) 2003-01-17 2011-01-12 トポターゲット ユーケー リミテッド Ｈｄａｃ阻害剤としてのエステル又はケトン結合を含むカルバミン酸化合物
AU2004276337B2 (en) 2003-09-24 2009-11-12 Methylgene Inc. Inhibitors of histone deacetylase
JP2005272419A (ja) 2004-03-26 2005-10-06 Nippon Kayaku Co Ltd ヒストン脱アセチル化酵素阻害剤
US8168658B2 (en) 2006-02-28 2012-05-01 Merck Sharp & Dohme Corp. Inhibitors of histone deacetylase
WO2008078762A1 (ja) * 2006-12-26 2008-07-03 Santen Pharmaceutical Co., Ltd. ウレア構造を有する新規ｎ－(２－アミノフェニル)ベンズアミド誘導体
WO2008123395A1 (ja) * 2007-03-28 2008-10-16 Santen Pharmaceutical Co., Ltd. ヒストン脱アセチル化酵素阻害作用を有する化合物を有効成分として含有する眼圧下降剤
US8012972B2 (en) 2007-03-28 2011-09-06 Santen Pharmaceutical Co., Ltd. Pyridinecarboxylic acid (2-aminophenyl) amide derivative having urea structure

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EP2292611A4 (en) 2011-06-22
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US8288380B2 (en) 2012-10-16
US20110077244A1 (en) 2011-03-31
EP2292611A1 (en) 2011-03-09
ES2389754T3 (es) 2012-10-31
KR20110028262A (ko) 2011-03-17
US8198271B2 (en) 2012-06-12
JP2010001289A (ja) 2010-01-07
EP2292611B1 (en) 2012-07-25
CN102036978A (zh) 2011-04-27
WO2009142321A1 (ja) 2009-11-26

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