PL2297297T3 - Wytwarzanie kwasu bursztynowego przez fermentację w niskim pH - Google Patents
Wytwarzanie kwasu bursztynowego przez fermentację w niskim pHInfo
- Publication number
- PL2297297T3 PL2297297T3 PL09779520T PL09779520T PL2297297T3 PL 2297297 T3 PL2297297 T3 PL 2297297T3 PL 09779520 T PL09779520 T PL 09779520T PL 09779520 T PL09779520 T PL 09779520T PL 2297297 T3 PL2297297 T3 PL 2297297T3
- Authority
- PL
- Poland
- Prior art keywords
- fermentation
- low
- succinic acid
- acid production
- production
- Prior art date
Links
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 title 2
- 230000004151 fermentation Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000001384 succinic acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01006—Fumarate reductase (NADH) (1.3.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/05—Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
- C12Y103/05004—Fumarate reductase (menaquinone) (1.3.5.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01032—Phosphoenolpyruvate carboxykinase (GTP) (4.1.1.32)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01038—Phosphoenolpyruvate carboxykinase (diphosphate) (4.1.1.38)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01049—Phosphoenolpyruvate carboxykinase (ATP) (4.1.1.49)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01002—Fumarate hydratase (4.2.1.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08159891 | 2008-07-08 | ||
| EP09779520.7A EP2297297B1 (en) | 2008-07-08 | 2009-05-20 | Succinic acid production by fermentation at low ph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2297297T3 true PL2297297T3 (pl) | 2017-08-31 |
Family
ID=40329358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09779520T PL2297297T3 (pl) | 2008-07-08 | 2009-05-20 | Wytwarzanie kwasu bursztynowego przez fermentację w niskim pH |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9012187B2 (pl) |
| EP (2) | EP2297297B1 (pl) |
| CN (3) | CN107267562A (pl) |
| BR (1) | BRPI0915534B1 (pl) |
| CA (1) | CA2730595C (pl) |
| EA (1) | EA018463B1 (pl) |
| ES (1) | ES2623932T3 (pl) |
| PL (1) | PL2297297T3 (pl) |
| UA (1) | UA103033C2 (pl) |
| WO (1) | WO2010003728A1 (pl) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010003728A1 (en) * | 2008-07-08 | 2010-01-14 | Dsm Ip Assets B.V. | Dicarboxylic acid production by fermentation at low ph |
| WO2010118932A1 (en) * | 2009-04-15 | 2010-10-21 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| US20120156761A1 (en) | 2009-07-02 | 2012-06-21 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| AU2010289725A1 (en) | 2009-09-01 | 2012-04-05 | Novozymes, Inc. | Methods for improving malic acid production in filamentous fungi |
| CN102812127B (zh) * | 2010-03-09 | 2014-12-03 | 三菱化学株式会社 | 琥珀酸的制造方法 |
| CN102918017B (zh) | 2010-03-26 | 2014-12-17 | 生物琥珀酸有限公司 | 从含有琥珀酸二铵、琥珀酸一铵和/或琥珀酸的发酵液制备琥珀酸一铵的方法及琥珀酸一铵到琥珀酸的转化 |
| CN102947259A (zh) | 2010-04-01 | 2013-02-27 | 生物琥珀酸国际责任有限公司 | 从琥珀酸盐制备四氢呋喃、γ-丁内酯和/或丁二醇的方法 |
| US8399687B2 (en) | 2010-04-01 | 2013-03-19 | Bioamber International S.A.R.L. | Processes for the production of hydrogenated products |
| US20110269993A1 (en) | 2010-04-30 | 2011-11-03 | Bioamber S.A.S. | Processes for producing adipic acid from fermentation broths containing diammonium adipate |
| US8895779B2 (en) | 2010-04-30 | 2014-11-25 | Bioamber Inc. | Processes for producing monoammonium adipate and conversion of monoammonium adipate to adipic acid |
| BR112012027464A2 (pt) | 2010-06-04 | 2019-09-24 | Novozymes Inc | célula hospedeira, método para produzir um ácido dicarboxílico c4, e, método para aumentar a produção de ácido dicarboxílico c4. |
| CA2800280A1 (en) | 2010-06-16 | 2011-12-22 | Bioamber S.A.S. | Processes for producing caprolactam and derivatives thereof from fermentation broths containing diammonium adipate or monoammonium adipate |
| BR112012031818A2 (pt) | 2010-06-16 | 2019-09-24 | Bioamber Sas | processos para a produção de produtos hidrogenados e derivados dos mesmos. |
| BR112012031744A2 (pt) | 2010-06-16 | 2016-09-13 | Bioamber Sas | processos para a produção de hexametilenodiamina (hmd), adiponitrila (adn), adipamida (adm) e seus derivados |
| JP2013531657A (ja) | 2010-06-16 | 2013-08-08 | ビオアンブ，ソシエテ パ アクシオンス シンプリフィエ | 水素化産物とそれらの誘導体の製造方法 |
| CN103108858A (zh) | 2010-06-16 | 2013-05-15 | 生物琥珀酸有限公司 | 己二胺（hmd）、己二腈（adn）、己二酰胺（adm）及其衍生物的制备方法 |
| CN102985408A (zh) | 2010-06-16 | 2013-03-20 | 生物琥珀酸有限公司 | 从含有己二酸二铵、己二酸一铵和/或己二酸的发酵液制备己内酰胺及其衍生物的方法 |
| CN102947458B (zh) | 2010-06-21 | 2016-05-04 | 诺维信股份有限公司 | 用于丝状真菌中c4-二羧酸的改善的产生的方法 |
| WO2011163269A1 (en) | 2010-06-21 | 2011-12-29 | Novozymes, Inc. | Aspergillus aculeatus derived polypeptides having c4-dicarboxylic acid transporter activity and polynucleotides encoding same |
| WO2012038390A1 (en) * | 2010-09-24 | 2012-03-29 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| US9605285B2 (en) | 2011-01-25 | 2017-03-28 | Cargill, Incorporated | Compositions and methods for succinate production |
| WO2012118848A1 (en) | 2011-02-28 | 2012-09-07 | Novozymes, Inc. | Microorganism for c4-dicarboxylic acid production |
| US8343752B2 (en) | 2011-05-03 | 2013-01-01 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| US8728798B2 (en) | 2011-05-03 | 2014-05-20 | Verdezyne, Inc. | Biological methods for preparing adipic acid |
| WO2012170060A1 (en) | 2011-06-10 | 2012-12-13 | Bioamber S.A.S. | Processes for producing hexanediol (hdo), hexamethylenediamine (hmd), and derivatives thereof |
| BR112014003444A2 (pt) | 2011-08-19 | 2017-03-14 | Novozymes Inc | célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico |
| DE102011056297A1 (de) * | 2011-12-12 | 2013-06-13 | Thyssenkrupp Uhde Gmbh | Verfahren zur biotechnischen Herstellung von Dicarbonsäuren |
| EP2807262A4 (en) * | 2012-01-25 | 2015-12-30 | Bioamber Internat S A R L | PROCESS FOR SUCCINATE MANUFACTURE |
| US9850507B2 (en) | 2012-07-25 | 2017-12-26 | Cargill, Incorporated | Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme |
| JP2015528312A (ja) | 2012-09-14 | 2015-09-28 | ミリアント・コーポレイションＭｙｒｉａｎｔ Ｃｏｒｐｏｒａｔｉｏｎ | 低ｐＨ条件下での発酵による有機酸の生産 |
| US20150232691A1 (en) | 2012-09-17 | 2015-08-20 | Ndsu Research Foundation | Blocked bio-based carboxylic acids and their use in thermosetting materials |
| CN118652942A (zh) | 2013-07-18 | 2024-09-17 | 德希尼布能源法国公司 | 发酵方法 |
| ES2790573T3 (es) * | 2013-12-12 | 2020-10-28 | Dsm Ip Assets Bv | Fumarato reductasas |
| US10801050B2 (en) | 2015-10-23 | 2020-10-13 | Metabolic Explorer | Microorganism modified for the assimilation of levulinic acid |
| CN109689864B (zh) * | 2016-07-13 | 2023-04-04 | 帝斯曼知识产权资产管理有限公司 | 苹果酸脱氢酶 |
| JP2020525026A (ja) | 2017-06-30 | 2020-08-27 | ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド | コハク酸産生が増加した遺伝子組換え酵母 |
| CN110218746A (zh) * | 2018-03-01 | 2019-09-10 | 上海凯赛生物技术研发中心有限公司 | 发酵生产长链二元酸的方法及发酵液、发酵处理液、污水 |
| KR102129379B1 (ko) | 2018-10-10 | 2020-07-02 | 한국과학기술원 | 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법 |
| CN115947809B (zh) * | 2022-11-02 | 2025-05-02 | 杭州宝晶生物股份有限公司 | 一种苹果酸转运蛋白突变体及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4877731A (en) | 1988-06-27 | 1989-10-31 | E. I. Du Pont De Nemours And Company | Fermentation process for carboxylic acids |
| US5573931A (en) | 1995-08-28 | 1996-11-12 | Michigan Biotechnology Institute | Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants |
| US5869301A (en) | 1995-11-02 | 1999-02-09 | Lockhead Martin Energy Research Corporation | Method for the production of dicarboxylic acids |
| US6475759B1 (en) * | 1997-10-14 | 2002-11-05 | Cargill, Inc. | Low PH lactic acid fermentation |
| WO2000071738A1 (en) | 1999-05-21 | 2000-11-30 | Cargill Dow Llc | Methods and materials for the synthesis of organic products |
| ES2529254T3 (es) * | 2002-05-30 | 2015-02-18 | Cargill Inc. | Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso |
| JP4647391B2 (ja) * | 2005-05-20 | 2011-03-09 | 財団法人地球環境産業技術研究機構 | コリネ型細菌による高効率なジカルボン酸の製造方法 |
| DE102005052338A1 (de) * | 2005-07-19 | 2007-05-16 | Leibniz Inst Naturstoff Forsch | Verfahren zur Herstellung von methylierten Malonsäuren durch mikrobielle Fermentation |
| US20080090273A1 (en) | 2005-11-21 | 2008-04-17 | Aaron Adriaan Winkler | Malic Acid Production in Recombinant Yeast |
| WO2007106524A2 (en) * | 2006-03-13 | 2007-09-20 | Cargill Inc. | Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol |
| WO2008000632A1 (en) | 2006-06-29 | 2008-01-03 | Dsm Ip Assets B.V. | A method for achieving improved polypeptide expression |
| EP2158323A4 (en) | 2007-05-18 | 2011-06-22 | Microbia Prec Engineering Inc | PRODUCTION OF ORGANIC ACID BY PILZ CELLS |
| EP2155885A4 (en) * | 2007-05-18 | 2010-12-01 | Microbia Prec Engineering Inc | ACIDIC ACID PRODUCTION IN RECOMBINANT YEAST |
| ATE555203T1 (de) | 2007-11-20 | 2012-05-15 | Dsm Ip Assets Bv | Dicarbonsäureproduktion in eukaryonten |
| WO2010003728A1 (en) * | 2008-07-08 | 2010-01-14 | Dsm Ip Assets B.V. | Dicarboxylic acid production by fermentation at low ph |
-
2009
- 2009-05-20 WO PCT/EP2009/056181 patent/WO2010003728A1/en not_active Ceased
- 2009-05-20 CN CN201710244247.1A patent/CN107267562A/zh active Pending
- 2009-05-20 US US13/003,217 patent/US9012187B2/en active Active
- 2009-05-20 UA UAA201101388A patent/UA103033C2/ru unknown
- 2009-05-20 EP EP09779520.7A patent/EP2297297B1/en active Active
- 2009-05-20 EA EA201100156A patent/EA018463B1/ru not_active IP Right Cessation
- 2009-05-20 EP EP16206648.4A patent/EP3176265A1/en not_active Withdrawn
- 2009-05-20 BR BRPI0915534-1A patent/BRPI0915534B1/pt active IP Right Grant
- 2009-05-20 CA CA2730595A patent/CA2730595C/en active Active
- 2009-05-20 CN CN2009801269436A patent/CN102089436A/zh active Pending
- 2009-05-20 PL PL09779520T patent/PL2297297T3/pl unknown
- 2009-05-20 CN CN201710243972.7A patent/CN107267561A/zh active Pending
- 2009-05-20 ES ES09779520.7T patent/ES2623932T3/es active Active
-
2015
- 2015-03-19 US US14/662,594 patent/US9340805B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107267562A (zh) | 2017-10-20 |
| US20110229945A1 (en) | 2011-09-22 |
| ES2623932T3 (es) | 2017-07-12 |
| BRPI0915534B1 (pt) | 2021-04-20 |
| CA2730595C (en) | 2014-12-16 |
| EA201100156A1 (ru) | 2011-08-30 |
| EA018463B1 (ru) | 2013-08-30 |
| BRPI0915534A2 (pt) | 2020-08-18 |
| EP2297297B1 (en) | 2017-02-08 |
| WO2010003728A1 (en) | 2010-01-14 |
| US9012187B2 (en) | 2015-04-21 |
| US20150232891A1 (en) | 2015-08-20 |
| CN107267561A (zh) | 2017-10-20 |
| EP3176265A1 (en) | 2017-06-07 |
| US9340805B2 (en) | 2016-05-17 |
| CA2730595A1 (en) | 2010-01-14 |
| EP2297297A1 (en) | 2011-03-23 |
| CN102089436A (zh) | 2011-06-08 |
| UA103033C2 (ru) | 2013-09-10 |
| WO2010003728A4 (en) | 2010-04-08 |
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