PL2316419T3 - Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia bakteryjnych infekcji dróg oddechowych - Google Patents

Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia bakteryjnych infekcji dróg oddechowych

Info

Publication number: PL2316419T3
Authority: PL; Poland
Prior art keywords: treatment; respiratory infections; bacterial respiratory; tobramycin combination; fosfomycin
Prior art date: 2004-05-17

Application number

PL10182347T

Other languages

English (en)

Inventor

William Baker

David Macleod

Original Assignee

Gilead Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-17

Filing date

2005-05-02

Publication date

2012-12-31

2005-05-02 Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc

2012-12-31 Publication of PL2316419T3 publication Critical patent/PL2316419T3/pl

Links

206010057190 Respiratory tract infections Diseases 0.000 title 1
230000001580 bacterial effect Effects 0.000 title 1
YMDXZJFXQJVXBF-STHAYSLISA-N fosfomycin Chemical compound C[C@@H]1O[C@@H]1P(O)(O)=O YMDXZJFXQJVXBF-STHAYSLISA-N 0.000 title 1
229960000308 fosfomycin Drugs 0.000 title 1
NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 title 1
229960000707 tobramycin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Otolaryngology (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Dispersion Chemistry (AREA)
Mechanical Engineering (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

PL10182347T 2004-05-17 2005-05-02 Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia bakteryjnych infekcji dróg oddechowych PL2316419T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US57173904P	2004-05-17	2004-05-17
US65900505P	2005-03-03	2005-03-03
EP05772820A EP1750667B1 (en)	2004-05-17	2005-05-02	Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections
EP10182347A EP2316419B1 (en)	2004-05-17	2005-05-02	Aerosolized fosfomycin/tobramycin combination for the treatment of bacterial respiratory infections

Publications (1)

Publication Number	Publication Date
PL2316419T3 true PL2316419T3 (pl)	2012-12-31

Family

ID=35394588

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PL10182347T PL2316419T3 (pl)	2004-05-17	2005-05-02	Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia bakteryjnych infekcji dróg oddechowych
PL10168285T PL2266534T3 (pl)	2004-05-17	2005-05-02	Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia mukowiscydozy
PL05772820T PL1750667T3 (pl)	2004-05-17	2005-05-02	Aerozolizowana kombinacja fosfomycyny/aminoglikozydu do leczenia bakteryjnych zakażeń oddechowych

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
PL10168285T PL2266534T3 (pl)	2004-05-17	2005-05-02	Aerolizowana kombinacja fosfomycyna/tobramycyna do leczenia mukowiscydozy
PL05772820T PL1750667T3 (pl)	2004-05-17	2005-05-02	Aerozolizowana kombinacja fosfomycyny/aminoglikozydu do leczenia bakteryjnych zakażeń oddechowych

Country Status (18)

Country	Link
US (4)	US7943118B2 (pl)
EP (3)	EP1750667B1 (pl)
JP (1)	JP4745340B2 (pl)
AR (1)	AR048793A1 (pl)
AT (1)	ATE493969T1 (pl)
AU (2)	AU2005244153B2 (pl)
BR (1)	BRPI0509026A (pl)
CA (1)	CA2564546C (pl)
CY (3)	CY1112004T1 (pl)
DE (1)	DE602005025754D1 (pl)
DK (3)	DK2266534T3 (pl)
ES (3)	ES2388420T3 (pl)
IL (2)	IL179277A (pl)
PL (3)	PL2316419T3 (pl)
PT (3)	PT2316419E (pl)
SI (3)	SI1750667T1 (pl)
TW (1)	TWI409074B (pl)
WO (1)	WO2005110022A2 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0509026A (pt)	2004-05-17	2007-09-18	Corus Pharma Inc	formulação de aerossol, método para a prevenção e tratamento de infecção causada por bactéria do trato respiratório, e, solução
US20060210483A1 (en) *	2005-03-02	2006-09-21	Kodsi Robert E	Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
ES2666276T3 (es)	2006-10-11	2018-05-03	Laboratoires Smb Sa	Composición farmacéutica antiinfecciosa para inhalación
WO2008071197A1 (en) *	2006-12-11	2008-06-19	Drugrecure Aps	Methods for treating cystic fibrosis or pneumonia with bacterial infection via pulmonary administration of fosfomycin
EP2018864A1 (en)	2007-07-23	2009-01-28	Biomet Deutschland GmbH	Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
DE102008046610A1 (de) *	2008-09-09	2010-03-11	Biomet Deutschland Gmbh	Verwendung einer pharmazeutischen Zusammensetzung zur lokalen Infektionstherapie sowie Medizinprodukt
AU2009307875A1 (en) *	2008-10-21	2010-04-29	Gilead Sciences, Inc.	Fosfomycin/tobramycin combinations for the treatment and prevention of ophthalmic, otological and dermatological infections
US20110124589A1 (en) *	2009-11-24	2011-05-26	Gilead Sciences, Inc.	Inhaled fosfomycin/tobramycin for the treatment of chronic obstructive pulmonary disease
JP2013515079A (ja) *	2009-12-22	2013-05-02	カロバイオスファーマシューティカルズインコーポレイティッド	低レベルの病原性シュードモナス・エルギノーサ（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）感染症を有する患者のスタフィロコッカス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ）感染症を治療する方法
WO2012030513A2 (en) *	2010-08-30	2012-03-08	Cempra Pharmaceuticals Inc.	Methods of treating bacterial infections through pulmonary delivery of fusidic acid
WO2012154483A1 (en) *	2011-05-06	2012-11-15	Gilead Sciences, Inc.	Dry powder fosfomycin/tobramycin formulation for inhalation
US9572774B2 (en)	2011-05-19	2017-02-21	Savara Inc.	Dry powder vancomycin compositions and associated methods
US8826904B2 (en)	2011-07-12	2014-09-09	Cardeas Pharma Corporation	Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
CA2841272C (en)	2011-07-12	2019-01-15	Alan Bruce Montgomery	Formulations of amikacin and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (vap) and ventilator associated tracheal (vat) bronchitis
PL2567691T3 (pl) *	2011-09-12	2015-05-29	Meiji Seika Pharma Co Ltd	Kompozycje wodne obejmujące arbekacynę
CN105705138A (zh) *	2013-08-26	2016-06-22	卡迪斯制药公司	具有改进的化学性质的氨基糖苷类物质和磷霉素的组合制剂
EP3219305A1 (de)	2016-03-16	2017-09-20	Apostolos Georgopoulos	Fosfomycin-formulierung zur parenteralen verabreichung
IT201900007007A1 (it) *	2019-05-20	2020-11-20	Liofilchem Srl	Kit e metodo per il test di suscettibilità alla fosfomicina con il metodo dell’agar diluizione.
KR20230110501A (ko) *	2020-10-01	2023-07-24	미시시피 주립대학	육탄당 인산염과 접합된 약물 및 이를 제조하고 사용하는 방법
WO2024086892A1 (en) *	2022-10-26	2024-05-02	The George Institute for Global Health	Stable api formulations comprising micronized tobramycin

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5750919A (en)	1980-09-16	1982-03-25	Meiji Seika Kaisha Ltd	Agent for reducing side effect
JPS58134028A (ja)	1982-02-05	1983-08-10	Meiji Seika Kaisha Ltd	アミノ配糖体抗生物質腎毒性の軽減乃至予防剤
GB9103291D0 (en) *	1991-02-15	1991-04-03	Waverley Pharma Ltd	Transfer adaptor
US5488038A (en) *	1992-11-27	1996-01-30	Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai	Dibekacin derivatives and arbekacin derivatives active against resistant bacteria
US5508269A (en) *	1994-10-19	1996-04-16	Pathogenesis Corporation	Aminoglycoside formulation for aerosolization
JPH09183730A (ja)	1995-05-10	1997-07-15	Meiji Seika Kaisha Ltd	ホスホマイシン鏡像異性体を含んでなる医薬
US6083922A (en) *	1996-04-02	2000-07-04	Pathogenesis, Corp.	Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
US20020017295A1 (en) *	2000-07-07	2002-02-14	Weers Jeffry G.	Phospholipid-based powders for inhalation
WO1999017782A1 (en) *	1997-10-03	1999-04-15	Meiji Seika Kaisha Ltd.	Composition for treatment of diabetes and treatment of diabetes
BR9916296A (pt)	1998-12-17	2004-06-29	Pathogenesis Corp	Método para tratamento de bronquite crÈnica severa (bronquiectase) com um antibiótico em forma de aerossol
US20020061281A1 (en) *	1999-07-06	2002-05-23	Osbakken Robert S.	Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
NZ523693A (en)	2000-07-10	2004-08-27	Chiron Corp	Macrolide formulations for inhalation and methods of treatment of endobronchial infections
EP1383376A4 (en)	2001-03-19	2006-03-08	Praecis Pharm Inc	PHARMACEUTICAL FORMULATIONS WITH PROLONGED RELEASE
ATE322249T1 (de) *	2001-05-18	2006-04-15	Chiron Corp	System zur abgabe einer tobramycin-formulierung
DE60103527T2 (de) *	2001-07-02	2005-06-16	Chiesi Farmaceutici S.P.A.	Optimierte Tobramycin-Formulierung zur Aerosolbildung
JP2005508220A (ja) *	2001-10-24	2005-03-31	パーリ・ゲーエムベーハー	薬用組成物調製用具
TW200403072A (en) *	2002-01-23	2004-03-01	Upjohn Co	Combination therapy for the treatment of bacterial infections
US7452524B2 (en) *	2004-01-27	2008-11-18	Gilead Sciences, Inc.	Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
BRPI0509026A (pt)	2004-05-17	2007-09-18	Corus Pharma Inc	formulação de aerossol, método para a prevenção e tratamento de infecção causada por bactéria do trato respiratório, e, solução
US7838532B2 (en)	2005-05-18	2010-11-23	Mpex Pharmaceuticals, Inc.	Aerosolized fluoroquinolones and uses thereof
JP5324223B2 (ja)	2005-12-08	2013-10-23	トランセイブ，インク．	肺感染症を治療する抗感染薬の脂質ベースの組成物及びその使用法
WO2008071197A1 (en)	2006-12-11	2008-06-19	Drugrecure Aps	Methods for treating cystic fibrosis or pneumonia with bacterial infection via pulmonary administration of fosfomycin
WO2008106584A1 (en)	2007-02-28	2008-09-04	Paringenix, Inc.	O-desulfated heparins treating acute exacerbations of chronic obstructive pulmonary disease
US8314239B2 (en)	2008-10-23	2012-11-20	Vertex Pharmaceutical Incorporated	Modulators of cystic fibrosis transmembrane conductance regulator
TWI465449B (zh)	2008-10-23	2014-12-21	Vertex Pharma	囊腫性纖維化跨膜傳導調節因子之調控因子
US20110124589A1 (en)	2009-11-24	2011-05-26	Gilead Sciences, Inc.	Inhaled fosfomycin/tobramycin for the treatment of chronic obstructive pulmonary disease

2005
- 2005-05-02 BR BRPI0509026-1A patent/BRPI0509026A/pt active Search and Examination
- 2005-05-02 DK DK10168285.4T patent/DK2266534T3/da active
- 2005-05-02 ES ES10182347T patent/ES2388420T3/es not_active Expired - Lifetime
- 2005-05-02 PT PT10182347T patent/PT2316419E/pt unknown
- 2005-05-02 EP EP05772820A patent/EP1750667B1/en not_active Expired - Lifetime
- 2005-05-02 SI SI200531250T patent/SI1750667T1/sl unknown
- 2005-05-02 WO PCT/US2005/014690 patent/WO2005110022A2/en not_active Ceased
- 2005-05-02 EP EP10182347A patent/EP2316419B1/en not_active Expired - Lifetime
- 2005-05-02 AU AU2005244153A patent/AU2005244153B2/en not_active Ceased
- 2005-05-02 DE DE602005025754T patent/DE602005025754D1/de not_active Expired - Lifetime
- 2005-05-02 JP JP2007527253A patent/JP4745340B2/ja not_active Expired - Fee Related
- 2005-05-02 US US11/596,566 patent/US7943118B2/en not_active Expired - Fee Related
- 2005-05-02 DK DK10182347.4T patent/DK2316419T3/da active
- 2005-05-02 AT AT05772820T patent/ATE493969T1/de active
- 2005-05-02 PT PT10168285T patent/PT2266534E/pt unknown
- 2005-05-02 EP EP10168285A patent/EP2266534B1/en not_active Expired - Lifetime
- 2005-05-02 ES ES05772820T patent/ES2358024T3/es not_active Expired - Lifetime
- 2005-05-02 DK DK05772820.6T patent/DK1750667T3/da active
- 2005-05-02 ES ES10168285T patent/ES2392389T3/es not_active Expired - Lifetime
- 2005-05-02 SI SI200531577T patent/SI2316419T1/sl unknown
- 2005-05-02 PT PT05772820T patent/PT1750667E/pt unknown
- 2005-05-02 SI SI200531600T patent/SI2266534T1/sl unknown
- 2005-05-02 PL PL10182347T patent/PL2316419T3/pl unknown
- 2005-05-02 CA CA2564546A patent/CA2564546C/en not_active Expired - Fee Related
- 2005-05-02 PL PL10168285T patent/PL2266534T3/pl unknown
- 2005-05-02 PL PL05772820T patent/PL1750667T3/pl unknown
- 2005-05-16 TW TW094115733A patent/TWI409074B/zh not_active IP Right Cessation
- 2005-05-16 AR ARP050101997A patent/AR048793A1/es not_active Application Discontinuation
2006
- 2006-11-14 IL IL179277A patent/IL179277A/en active IP Right Grant
2009
- 2009-12-07 AU AU2009243536A patent/AU2009243536B2/en not_active Ceased
2010
- 2010-12-14 US US12/967,645 patent/US8361444B2/en not_active Expired - Fee Related
2011
- 2011-03-09 CY CY20111100268T patent/CY1112004T1/el unknown
- 2011-04-13 US US13/085,576 patent/US8409549B2/en not_active Expired - Fee Related
2012
- 2012-09-05 CY CY20121100798T patent/CY1113283T1/el unknown
- 2012-09-14 US US13/616,544 patent/US8980226B2/en not_active Expired - Fee Related
- 2012-11-09 CY CY20121101067T patent/CY1113319T1/el unknown
2013
- 2013-04-02 IL IL225529A patent/IL225529A/en active IP Right Grant

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CY1112004T1 (el)	2015-11-04
CY1113283T1 (el)	2016-04-13
ES2392389T3 (es)	2012-12-10
ES2388420T3 (es)	2012-10-15
PL1750667T3 (pl)	2011-06-30
US8361444B2 (en)	2013-01-29
TW200608983A (en)	2006-03-16
DK2266534T3 (da)	2013-01-14
WO2005110022A3 (en)	2006-04-06
ATE493969T1 (de)	2011-01-15
CA2564546A1 (en)	2005-11-24
US20130071442A1 (en)	2013-03-21
SI2266534T1 (sl)	2012-12-31
IL225529A (en)	2014-08-31
AR048793A1 (es)	2006-05-24
EP1750667A2 (en)	2007-02-14
SI2316419T1 (sl)	2012-10-30
WO2005110022A2 (en)	2005-11-24
PT1750667E (pt)	2011-03-11
PT2266534E (pt)	2012-10-09
TWI409074B (zh)	2013-09-21
EP2316419B1 (en)	2012-07-11
HK1151191A1 (en)	2012-01-27
IL179277A (en)	2013-04-30
US20070218013A1 (en)	2007-09-20
US8409549B2 (en)	2013-04-02
ES2358024T3 (es)	2011-05-04
BRPI0509026A (pt)	2007-09-18
CA2564546C (en)	2013-02-26
PT2316419E (pt)	2012-10-22
JP2007538075A (ja)	2007-12-27
SI1750667T1 (sl)	2011-04-29
AU2005244153A1 (en)	2005-11-24
EP2266534A1 (en)	2010-12-29
DE602005025754D1 (de)	2011-02-17
EP1750667B1 (en)	2011-01-05
US20110117030A1 (en)	2011-05-19
IL179277A0 (en)	2007-05-15
EP2316419A1 (en)	2011-05-04
PL2266534T3 (pl)	2013-02-28
EP1750667A4 (en)	2007-07-11
AU2005244153B2 (en)	2009-10-29
AU2009243536A1 (en)	2009-12-24
HK1157637A1 (en)	2012-07-06
EP2266534B1 (en)	2012-09-26
AU2009243536B2 (en)	2012-03-22
US7943118B2 (en)	2011-05-17
US20110189103A1 (en)	2011-08-04
JP4745340B2 (ja)	2011-08-10
IL225529A0 (en)	2013-06-27
CY1113319T1 (el)	2016-04-13
DK1750667T3 (da)	2011-04-26
DK2316419T3 (da)	2012-10-22
US8980226B2 (en)	2015-03-17

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