PL2316530T3 - Triglicerydy, kwasy tłuszczowe i alkohole jako modulatory oun - Google Patents

Triglicerydy, kwasy tłuszczowe i alkohole jako modulatory oun

Info

Publication number
PL2316530T3
PL2316530T3 PL10184846T PL10184846T PL2316530T3 PL 2316530 T3 PL2316530 T3 PL 2316530T3 PL 10184846 T PL10184846 T PL 10184846T PL 10184846 T PL10184846 T PL 10184846T PL 2316530 T3 PL2316530 T3 PL 2316530T3
Authority
PL
Poland
Prior art keywords
triglycerides
alcohols
fatty acids
cns modulators
cns
Prior art date
Application number
PL10184846T
Other languages
English (en)
Inventor
Wilfred Dimpfel
David Greenwood
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Publication of PL2316530T3 publication Critical patent/PL2316530T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL10184846T 2004-05-12 2005-05-12 Triglicerydy, kwasy tłuszczowe i alkohole jako modulatory oun PL2316530T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57013704P 2004-05-12 2004-05-12
GB0420856A GB0420856D0 (en) 2004-09-20 2004-09-20 Cns modulators
EP10184846.3A EP2316530B1 (en) 2004-05-12 2005-05-12 Triglycerides, fatty acids, alcohols as cns modulators
EP05742109.1A EP1755743B1 (en) 2004-05-12 2005-05-12 Beta hydroxybutyrate and derivatives for treating depression and anxiety

Publications (1)

Publication Number Publication Date
PL2316530T3 true PL2316530T3 (pl) 2015-01-30

Family

ID=33306877

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10184846T PL2316530T3 (pl) 2004-05-12 2005-05-12 Triglicerydy, kwasy tłuszczowe i alkohole jako modulatory oun
PL05742109T PL1755743T3 (pl) 2004-05-12 2005-05-12 Beta-hydroksymaślan i pochodne do leczenia depresji i lęku

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL05742109T PL1755743T3 (pl) 2004-05-12 2005-05-12 Beta-hydroksymaślan i pochodne do leczenia depresji i lęku

Country Status (8)

Country Link
US (3) US20080058416A1 (pl)
EP (2) EP1755743B1 (pl)
DK (2) DK2316530T3 (pl)
ES (2) ES2513890T3 (pl)
GB (1) GB0420856D0 (pl)
PL (2) PL2316530T3 (pl)
PT (1) PT1755743E (pl)
WO (1) WO2005107875A2 (pl)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0427145D0 (en) * 2004-12-10 2005-01-12 Ketocytonyx Inc Compositions for use in surgery
US8728532B2 (en) 2007-04-12 2014-05-20 Regents Of The University Of Minnesota Ischemia/reperfusion protection compositions and methods of using
PE20151949A1 (es) 2013-03-19 2016-01-05 Univ South Florida Composiciones y metodos para producir cetosis elevada y sostenida
WO2015184279A1 (en) * 2014-05-30 2015-12-03 The Johns Hopkins University Compositions and methods for treating kabuki syndrome and related disorders
US10980764B1 (en) * 2016-02-01 2021-04-20 University Of South Florida Exogenous ketone supplements for reducing anxiety-related behavior
US11185518B2 (en) 2017-12-19 2021-11-30 Axcess Global Sciences, Llc S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer
US10736861B2 (en) 2016-03-11 2020-08-11 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US10973792B2 (en) 2019-02-13 2021-04-13 Axcess Global Sciences, Llc Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use
US11103470B2 (en) 2017-11-22 2021-08-31 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US11241403B2 (en) 2016-03-11 2022-02-08 Axcess Global Sciences, Llc Beta-hydroxybutyrate mixed salt compositions and methods of use
US10973786B2 (en) 2016-03-11 2021-04-13 Axcess Global Sciences, Llc R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions
US12521378B2 (en) 2016-04-19 2026-01-13 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans
US11806324B2 (en) 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
US20230346721A1 (en) 2018-04-18 2023-11-02 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for delivery of ketone bodies
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US12533346B2 (en) 2016-04-19 2026-01-27 Axcess Global Sciences, Llc Administration of berberine metabolites
US11026929B2 (en) 2016-04-19 2021-06-08 Keto Patent Group, Inc. Administration of berberine metabolites
SG11201809211QA (en) * 2016-04-19 2018-11-29 Keto Patent Group Inc Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
WO2018009208A1 (en) * 2016-07-08 2018-01-11 Cognate Nutritionals, Inc. Nutritional mitiggation of the cns effects of traumatic brain injury
US20180057846A1 (en) 2016-08-30 2018-03-01 KetoneAid Inc. Partially buffered free acid and/or ketone blend for rapid onset ketosis and metabolic therapy
US10307398B2 (en) 2016-09-20 2019-06-04 Regents Of The University Of Minnesota Resuscitation composition and methods of making and using
WO2018081118A1 (en) 2016-10-24 2018-05-03 University Of South Florida Delaying latency to seizure by combinations of ketone supplements
US20180177753A1 (en) * 2016-12-23 2018-06-28 Neuroenergy Ventures, Inc. Glyceryl 3-hydroxybutyrates for migraine symptom management
US9925164B1 (en) * 2017-01-12 2018-03-27 Neuroenergy Ventures, Inc. Glyceryl 3-hydroxybutyrates for traumatic brain injury
US10376528B2 (en) 2017-03-10 2019-08-13 Tecton Group, Llc Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor
US12171735B2 (en) 2017-04-19 2024-12-24 Axcess Global Sciences, Llc Administration of butyrate, beta-hydroxybutyrate, cannabidiol, and related compounds in humans
US11760963B2 (en) 2017-08-23 2023-09-19 KetoneAid Inc. Ketogenic beer and alcoholic beverage mixture containing non-racemic ethyl 3-hydroxybutyrate and/or 1,3 butanediol
US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US11129802B2 (en) 2018-08-27 2021-09-28 Axcess Global Sciences, Llc Compositions and methods for delivering cannabidiol and ketone bodies
US11419836B2 (en) 2019-02-13 2022-08-23 Axcess Global Sciences, Llc Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions
US10980772B2 (en) 2018-08-27 2021-04-20 Axcess Global Sciences, Llc Compositions and methods for delivering tetrahydrocannabinol and ketone bodies
US11241401B2 (en) 2020-02-06 2022-02-08 Axcess Global Sciences, Llc Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions
US20200061023A1 (en) * 2018-08-27 2020-02-27 Axcess Global Sciences, Llc Compositions and methods for delivering tetrahydrocannabinol and ketone bodies
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
JP7403861B2 (ja) * 2019-05-30 2023-12-25 ニューロエナジー ベンチャーズ、インコーポレイテッド グリセリルトリス(β-ヒドロキシ酪酸)及びニューロン一過性虚血性発作
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11033553B2 (en) 2019-06-21 2021-06-15 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
WO2021195477A1 (en) 2020-03-27 2021-09-30 Ketoneaid, Inc. Ketone ester as a therapeutic treatment of covid-19, long covid, and related viral infections
US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
TWI804037B (zh) * 2021-11-02 2023-06-01 長庚醫療財團法人高雄長庚紀念醫院 生酮飲食之評估系統及其運作方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637726A (pl) * 1962-09-26
GB1476624A (en) * 1973-05-30 1977-06-16 Cepbepe Tranquiliser medicaments
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
DE2733202A1 (de) * 1976-08-04 1978-02-09 Agroferm Ag Verfahren zur herstellung der d(-)-3-hydroxybuttersaeure
US4067999A (en) * 1976-12-15 1978-01-10 Food Technology Products Control of hemorrhagic enteritis in turkeys
US4234599A (en) * 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism
US4351835A (en) * 1981-04-01 1982-09-28 Montefiore Hospital Method for preventing body fat deposition in mammals
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee
DE3229955A1 (de) * 1982-08-12 1984-02-16 Erichsen, Friedrich Karl, Dr., 2351 Schillsdorf Arzneimittel mit analgetischer wirkung
US4701443A (en) * 1983-03-22 1987-10-20 Baxter Travenol Laboratories, Inc. Nutrient polyesters
US5100677A (en) * 1985-12-18 1992-03-31 Veech Richard L Fluid therapy with various organic anions
DE3581407D1 (de) * 1985-09-06 1991-02-21 Nestle Sa Bewahrung lebender gewebe.
GB8525666D0 (en) * 1985-10-17 1985-11-20 Ici Plc Chemical process
US5719119A (en) * 1985-12-18 1998-02-17 British Technology Group, Ltd. Parenteral nutrition therapy with amino acids
EP0258273A1 (en) * 1985-12-20 1988-03-09 VEECH, Richard L. Preparation of electrolyte solutions and containers
US5126373A (en) * 1987-11-19 1992-06-30 Henri Brunengraber Composition for parenteral and oral nutrition
US4997976A (en) * 1988-11-15 1991-03-05 Henri Brunengraber Use of 1,3-butanediol acetoacetate in parenteral oral nutrition
US5292774A (en) * 1988-07-26 1994-03-08 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Substitution fluid preparation comprising 3-hydroxy-butyric acid (β-hydroxybutric acid) and its salts
US5116868A (en) * 1989-05-03 1992-05-26 The Johns Hopkins University Effective ophthalmic irrigation solution
EP0522422A3 (en) * 1991-07-01 1993-03-17 Mitsubishi Kasei Corporation Process for producing a biodegradable polymer
US5654266A (en) * 1992-02-10 1997-08-05 Chen; Chung-Ho Composition for tissues to sustain viability and biological functions in surgery and storage
US5348979A (en) * 1992-12-23 1994-09-20 Iowa State University Research Foundation Inc. Method of promoting nitrogen retention in humans
WO1995009144A1 (en) * 1993-09-30 1995-04-06 Eastman Chemical Company Nutritive water soluble glycerol esters of hydroxy butyric acid
US5912269A (en) * 1996-04-30 1999-06-15 Vertex Pharmaceuticals, Inc. Butyrate prodrugs derived from lactic acid
JP4598203B2 (ja) * 1995-12-01 2010-12-15 ビーティージー・インターナショナル・リミテッド 脳機能改善剤
JPH10158166A (ja) * 1996-12-02 1998-06-16 Taisho Pharmaceut Co Ltd 貼付剤
US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
AU6513298A (en) * 1997-03-17 1998-10-12 British Technology Group Limited Therapeutic compositions
CA2317314C (en) * 1998-01-07 2003-12-30 Metabolix, Inc. Animal nutrition compositions
NO308197B1 (no) * 1998-01-21 2000-08-14 Fideline Sammensetning og oppløsning derav for Õ minske stress, angst og agressivitet hos pattedyr inneholdende en blanding av fettsyrer eller derivater derav
CA2338090C (en) * 1998-07-22 2009-07-14 Metabolix, Inc. Nutritional and therapeutic compositions of 3-hydroxyacids for increasing blood ketone bodies
NZ509739A (en) * 1998-09-15 2003-10-31 Btg Int Ltd A cyclic ester of (R)-3-hydroxybutyrate useful for increasing cardiac efficiency
US6835750B1 (en) * 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
WO2001082928A1 (en) * 2000-05-01 2001-11-08 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism
CA2442343A1 (en) * 2001-02-07 2002-08-15 Serguei S. Likhodi Method of treating neurological disorders using acetone derivatives
US20020132846A1 (en) * 2001-02-26 2002-09-19 Caleb Stone Use of gamma substituted gamma-butyrolactones to increase levels of their corresponding substituted gamma-hydroxybutyrate derivatives in humans
US20040198819A1 (en) * 2001-06-20 2004-10-07 Young Aiping H. Biological response modifier composition and uses thereof
US6579543B1 (en) * 2002-02-22 2003-06-17 Jackie H. McClung Composition for topical application to skin
JP2003306430A (ja) * 2002-04-16 2003-10-28 Lion Corp 皮膚外用剤組成物
AU2004245567B2 (en) * 2003-06-03 2011-06-23 Oxford University Innovation Limited Nutritional supplements and therapeutic compositions comprising (R)-3-hydroxybutyrate derivatives
WO2005034874A2 (en) * 2003-10-08 2005-04-21 The Mclean Hospital Corporation Enhanced efficacy of omega-3 fatty acid therapy in the treatment of psychiatric disorders and other indications
CA2542023A1 (en) * 2003-10-08 2005-09-22 The Mclean Hospital Corporation Methods of treating psychiatric, substance abuse, and other disorders using combinations containing omega-3 fatty acids

Also Published As

Publication number Publication date
US20220202760A1 (en) 2022-06-30
EP2316530B1 (en) 2014-08-13
WO2005107875A3 (en) 2006-03-23
EP2316530A1 (en) 2011-05-04
ES2513890T3 (es) 2014-10-27
US20080058416A1 (en) 2008-03-06
DK2316530T3 (da) 2014-11-03
DK1755743T3 (da) 2013-06-10
WO2005107875A2 (en) 2005-11-17
PT1755743E (pt) 2013-06-03
US20140296337A1 (en) 2014-10-02
EP1755743B1 (en) 2013-04-24
PL1755743T3 (pl) 2013-08-30
GB0420856D0 (en) 2004-10-20
ES2410588T3 (es) 2013-07-02
EP1755743A2 (en) 2007-02-28

Similar Documents

Publication Publication Date Title
PL2316530T3 (pl) Triglicerydy, kwasy tłuszczowe i alkohole jako modulatory oun
MX286464B (es) Formulaciones de acido graso omega 3.
ZA200605354B (en) Prostaglandin nitrooxyderivatives
AU2013260698A1 (en) Method for producing polyunsaturated fatty acids
IL190728A0 (en) Intravenous essential fatty acid emulsion
IL181330A0 (en) Thiazolo-naphthyl acids
ZA200807982B (en) Method for producing polyunsaturated fatty acids
PL1709143T3 (pl) Enzymatyczne modyfikowanie tłuszczów triglicerydowych
EP1958612A4 (en) TREHALOSE FATTY ACID ESTER COMPOSITION
PL1765318T3 (pl) Średniołańcuchowe kwasy tłuszczowe przydatne jako środki przeciwdrobnoustrojowe
GB2444896B (en) Compositions comprising polyunsaturated fatty acids
EP1934362A4 (en) ENZYMATIC OIL TESTERIFICATION
IL184193A0 (en) Processes for the preparation of aminoethoxybenzyl alcohols
GB0428384D0 (en) Eicosapentaenoic acid
EP1854893A4 (en) PROCESS FOR PRODUCING OPTICALLY ACTIVE SECONDARY ALCOHOL
EP2092746A4 (en) DYNAMIC LAYOUTS
SG113608A1 (en) Split nut
PT1894576E (pt) Novo agente redutor dos níveis de triglicéridos
GB0501060D0 (en) Microcapsule
SG116559A1 (en) Process for producing wax ester from dihydroxy fatty acid.
PL1764210T3 (pl) Sposób sprasowania złomu
PL365353A1 (pl) Reaktor estrów olejowych
GB0606864D0 (en) Increades fatty acid oxidation
HU0402533D0 (en) Nonskidding surface for soaps
PL377674A1 (pl) Brykiety siarkowo-asfaltowe oraz sposób ich otrzymywania