PL2331687T3 - Środki przeciwdrobnoustrojowe - Google Patents

Środki przeciwdrobnoustrojowe

Info

Publication number
PL2331687T3
PL2331687T3 PL09782176T PL09782176T PL2331687T3 PL 2331687 T3 PL2331687 T3 PL 2331687T3 PL 09782176 T PL09782176 T PL 09782176T PL 09782176 T PL09782176 T PL 09782176T PL 2331687 T3 PL2331687 T3 PL 2331687T3
Authority
PL
Poland
Prior art keywords
antimicrobials
Prior art date
Application number
PL09782176T
Other languages
English (en)
Inventor
Yves Briers
Rob Lavigne
Guido Volckaert
Original Assignee
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leuven Kath filed Critical Univ Leuven Kath
Publication of PL2331687T3 publication Critical patent/PL2331687T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462Lysozyme (3.2.1.17)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL09782176T 2008-08-26 2009-08-25 Środki przeciwdrobnoustrojowe PL2331687T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0815484.1A GB0815484D0 (en) 2008-08-26 2008-08-26 Antibacterial agents
EP09782176A EP2331687B1 (en) 2008-08-26 2009-08-25 Antimicrobial agents
PCT/EP2009/060947 WO2010023207A2 (en) 2008-08-26 2009-08-25 Antimicrobial agents

Publications (1)

Publication Number Publication Date
PL2331687T3 true PL2331687T3 (pl) 2013-02-28

Family

ID=39846783

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09782176T PL2331687T3 (pl) 2008-08-26 2009-08-25 Środki przeciwdrobnoustrojowe

Country Status (16)

Country Link
US (1) US9809808B2 (pl)
EP (1) EP2331687B1 (pl)
JP (2) JP5153943B2 (pl)
KR (1) KR101473271B1 (pl)
CN (1) CN102197132B (pl)
AU (1) AU2009286760B2 (pl)
BR (1) BRPI0917508A2 (pl)
CA (1) CA2735077C (pl)
DK (1) DK2331687T3 (pl)
EA (1) EA024794B1 (pl)
ES (1) ES2395357T3 (pl)
GB (1) GB0815484D0 (pl)
IL (1) IL211441A (pl)
MX (1) MX2011001957A (pl)
PL (1) PL2331687T3 (pl)
WO (1) WO2010023207A2 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
EP2446028B1 (en) 2009-06-26 2018-04-04 Lysando Aktiengesellschaft Antimicrobial agents
PL2445515T3 (pl) 2009-06-26 2016-10-31 Środki przeciwdrobnoustrojowe
MX2012002216A (es) * 2009-08-24 2012-04-10 Univ Leuven Kath Nueva endolisina obpgplys.
AU2011247584B2 (en) * 2010-04-27 2016-01-14 Lysando Ag Method of reducing biofilms
ES2956367T3 (es) 2010-09-17 2023-12-20 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fago antibacteriano, péptidos de fago y sus métodos de uso
GB201018518D0 (en) * 2010-11-03 2010-12-15 Univ Leuven Kath Novel endolysin
EP2468856A1 (en) * 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimicrobial Agents
CN103857410A (zh) * 2011-04-21 2014-06-11 洛克菲勒大学 用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
WO2012146738A1 (en) * 2011-04-27 2012-11-01 Lysando Holding Ag New antimicrobial agents
US9068204B2 (en) 2013-03-15 2015-06-30 The United States Of America, As Represented By The Secretary Of Agriculture Peptidoglycan hydrolase antimicrobials for eradicating lactobacilli that contaminate and reduce ethanol yields in biofuel fermentation
WO2015070912A1 (en) 2013-11-14 2015-05-21 Lysando Ag Modified el188 endolysin sequence
WO2015070911A1 (en) 2013-11-14 2015-05-21 Lysando Ag Modified kz144 endolysin sequence
US10329550B2 (en) 2014-02-14 2019-06-25 Lysando Ag Antimicrobial agents
CA2941426C (en) * 2014-04-08 2022-09-27 Lysando Ag Pharmaceutical composition against chronic bacterial infections
JP6818349B2 (ja) * 2014-06-26 2021-01-20 ザ ロックフェラー ユニヴァーシティ アシネトバクター溶解素
CN104762285B (zh) * 2015-04-23 2017-10-27 武汉菲吉乐科生物科技有限公司 一种自内裂解大肠杆菌的裂解酶及其应用
EP3555121B1 (en) * 2016-12-16 2021-09-22 Universidade do Minho Novel endolysin
KR20240162610A (ko) * 2017-04-03 2024-11-15 사시나파스 컴퍼니 리미티드 조작된 그람-음성 엔도리신
IL303122A (en) 2017-12-12 2023-07-01 Contrafect Corp Identification of lysines and their derivatives with antibacterial activity against Pseudomonas aeruginosa
JP2021525072A (ja) 2018-05-30 2021-09-24 ライサンド アーゲー 新規抗微生物タンパク質
AU2019276252A1 (en) 2018-05-30 2020-11-26 Lysando Ag Novel antimicrobial fusion proteins
US20220315908A1 (en) * 2019-05-08 2022-10-06 Phagomed Biopharma Gmbh Novel gardnerella endolysins and uses thereof
WO2023225518A2 (en) * 2022-05-16 2023-11-23 The Broad Institute, Inc. Engineered pnma proteins and delivery systems thereof
CN117737001B (zh) * 2022-12-27 2024-08-09 菲吉乐科(南京)生物科技有限公司 一种防治犬细菌性腹泻的大肠杆菌噬菌体及其应用
CN118620800B (zh) * 2024-08-08 2024-11-12 中国兽医药品监察所 一株鼻疽伯克霍尔德氏菌及其应用

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ATE127838T1 (de) 1987-07-06 1995-09-15 Univ Louisiana State Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.
GB2255561B (en) * 1991-04-20 1995-06-21 Agricultural & Food Res Lysins from bacteriophages
DE69332740T2 (de) * 1992-08-21 2004-02-05 The University Of British Columbia, Vancouver Kationische peptide und verfahren zu deren herstellung
DK0778733T3 (da) 1994-09-01 2001-04-02 Novozymes As Basisk proteinsammensætning til at dræbe eller inhibere mikrobielle celler
US6503881B2 (en) * 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US5997862A (en) * 1997-10-31 1999-12-07 New Horizons Diagnostics Corporation Therapeutic treatment of group A streptococcal infections
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ES2346808T3 (es) 2006-03-31 2010-10-20 The University Court Of The University Of St. Andrews Composiciones antimicrobianas que comprenden un peptido cationico y una endopeptidasa de glicilglicina.
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US20100310522A1 (en) 2007-11-26 2010-12-09 Plant Bioscience Limited Novel Polypeptides Having Endolysin Activity and Uses Thereof
EP2318531A4 (en) 2008-07-24 2011-11-09 Us Agriculture TO RESISTANCE DEVELOPMENT REFRACTORY ANTIMICROBIAL ACTIVE SUBSTANCES
EP2157100A1 (en) 2008-08-19 2010-02-24 Profos AG Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
WO2010091294A2 (en) 2009-02-05 2010-08-12 The Regents Of The University Of California New targeted antimicrobial moieties
PL2445515T3 (pl) 2009-06-26 2016-10-31 Środki przeciwdrobnoustrojowe
MX2012002216A (es) 2009-08-24 2012-04-10 Univ Leuven Kath Nueva endolisina obpgplys.
AU2011247584B2 (en) 2010-04-27 2016-01-14 Lysando Ag Method of reducing biofilms

Also Published As

Publication number Publication date
MX2011001957A (es) 2011-06-20
EA201100312A1 (ru) 2011-10-31
EP2331687B1 (en) 2012-09-19
WO2010023207A2 (en) 2010-03-04
CN102197132B (zh) 2016-01-13
JP5571757B2 (ja) 2014-08-13
CN102197132A (zh) 2011-09-21
JP2012500642A (ja) 2012-01-12
CA2735077A1 (en) 2010-03-04
EP2331687A2 (en) 2011-06-15
JP5153943B2 (ja) 2013-02-27
US9809808B2 (en) 2017-11-07
CA2735077C (en) 2019-04-09
KR20110049883A (ko) 2011-05-12
EA024794B1 (ru) 2016-10-31
AU2009286760B2 (en) 2015-08-27
BRPI0917508A2 (pt) 2015-08-04
AU2009286760A1 (en) 2010-03-04
KR101473271B1 (ko) 2014-12-16
HK1157818A1 (en) 2012-07-06
ES2395357T3 (es) 2013-02-12
JP2013081465A (ja) 2013-05-09
GB0815484D0 (en) 2008-10-01
IL211441A (en) 2015-04-30
DK2331687T3 (da) 2013-01-07
WO2010023207A3 (en) 2010-07-15
US20110243915A1 (en) 2011-10-06

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