PL2336153T3 - Udoskonalone systemy ekspresji z układem wydzielania SEC - Google Patents

Udoskonalone systemy ekspresji z układem wydzielania SEC

Info

Publication number
PL2336153T3
PL2336153T3 PL10179651T PL10179651T PL2336153T3 PL 2336153 T3 PL2336153 T3 PL 2336153T3 PL 10179651 T PL10179651 T PL 10179651T PL 10179651 T PL10179651 T PL 10179651T PL 2336153 T3 PL2336153 T3 PL 2336153T3
Authority
PL
Poland
Prior art keywords
sec
expression systems
improved expression
system secretion
secretion
Prior art date
Application number
PL10179651T
Other languages
English (en)
Inventor
Diane M Retallack
Jane C Schneider
Thomas Martin Ramseier
Original Assignee
Pfenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfenex Inc filed Critical Pfenex Inc
Publication of PL2336153T3 publication Critical patent/PL2336153T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL10179651T 2003-11-21 2004-11-22 Udoskonalone systemy ekspresji z układem wydzielania SEC PL2336153T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52412403P 2003-11-21 2003-11-21
EP04817876A EP1687324B1 (en) 2003-11-21 2004-11-22 Improved expression systems with sec-system secretion
EP10179651.4A EP2336153B1 (en) 2003-11-21 2004-11-22 Improved expression systems with SEC-system secretion

Publications (1)

Publication Number Publication Date
PL2336153T3 true PL2336153T3 (pl) 2016-08-31

Family

ID=34994140

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10179615.9T PL2327718T3 (pl) 2003-11-21 2004-11-22 Ulepszone systemy ekspresyjne z wykorzystaniem systemu sekrecji SEC
PL10179651T PL2336153T3 (pl) 2003-11-21 2004-11-22 Udoskonalone systemy ekspresji z układem wydzielania SEC

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL10179615.9T PL2327718T3 (pl) 2003-11-21 2004-11-22 Ulepszone systemy ekspresyjne z wykorzystaniem systemu sekrecji SEC

Country Status (11)

Country Link
US (1) US7985564B2 (pl)
EP (4) EP2314602A1 (pl)
JP (1) JP5028551B2 (pl)
KR (1) KR101265343B1 (pl)
CN (1) CN1882605B (pl)
AU (1) AU2004317306B2 (pl)
BR (1) BRPI0416807A (pl)
CA (1) CA2546157C (pl)
MX (1) MXPA06005705A (pl)
PL (2) PL2327718T3 (pl)
WO (1) WO2005089093A2 (pl)

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US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
CA2546157C (en) 2003-11-21 2014-07-22 Dow Global Technolgies Inc. Improved expression systems with sec-system secretion
WO2006014899A2 (en) 2004-07-26 2006-02-09 Dow Global Technologies Inc. Process for improved protein expression by strain engineering
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US7618799B2 (en) * 2007-01-31 2009-11-17 Dow Global Technologies Inc Bacterial leader sequences for increased expression
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
KR101530395B1 (ko) 2007-04-27 2015-06-19 피페넥스 인크. 향상된 수율 및(또는) 품질로 이종 단백질을 발현하는 특정 균주를 동정하기 위해 미생물 숙주를 신속히 스크리닝하는 방법
US8318481B2 (en) 2007-12-07 2012-11-27 Pfenex Inc. High copy number self-replicating plasmids in pseudomonas
WO2010008764A1 (en) * 2008-06-23 2010-01-21 Dow Global Technologies Inc. Pseudomonas fluorescens strains for production of extracellular recombinant protein
CA2758885C (en) 2009-04-17 2018-09-11 Dow Agrosciences Llc Dig-3 insecticidal cry toxins
SI2512222T1 (en) 2009-12-16 2018-05-31 Dow Agrosciences Llc Combined use of Cry1Ca and Cry1Fa proteins for controlling insect resistance
NZ602255A (en) * 2010-03-04 2014-04-30 Pfenex Inc Method for producing soluble recombinant interferon protein without denaturing
US8530171B2 (en) 2010-03-30 2013-09-10 Pfenex Inc. High level expression of recombinant toxin proteins
CA2794740C (en) 2010-04-01 2019-12-31 Pfenex Inc. Methods for g-csf production in a pseudomonas host cell
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WO2013163654A2 (en) * 2012-04-27 2013-10-31 Pronutria, Inc. Nucleic acids, cells, and methods for producing secreted proteins
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
CN103254277B (zh) * 2013-05-03 2017-02-08 南京工业大学 强分泌性信号肽增强小肽模序及其应用
TW201542093A (zh) 2014-03-21 2015-11-16 艾格里遺傳學股份有限公司 用於控制玉米穗蟲之Ｃｒｙ１Ｄ
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RU2021134624A (ru) 2015-10-22 2022-03-15 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
WO2017068425A1 (en) 2015-10-22 2017-04-27 Juno Therapeutics Gmbh Methods for culturing cells and kits and apparatus for same
CN110035662B (zh) 2016-09-30 2022-09-30 美国陶氏益农公司 二元杀虫cry毒素
MA49288A (fr) 2017-04-27 2020-03-04 Juno Therapeutics Gmbh Reactifs particulaires oligomères et leurs méthodes d'utilisation
CN111278979B (zh) 2017-10-27 2024-05-31 佩利肯科技控股公司 重组大肠杆菌天冬酰胺酶的生产方法
US10787671B2 (en) 2017-10-27 2020-09-29 Pfenex Inc. Method for production of recombinant Erwinia asparaginase
DK3700915T3 (da) * 2017-10-27 2025-08-18 Pelican Tech Holdings Inc Bakterielle leader-sekvenser til periplasmisk proteinekspression
CN113584060B (zh) * 2018-08-07 2023-02-07 康码（上海）生物科技有限公司 信号肽相关序列及其在蛋白质合成中的应用
CN113227358A (zh) 2018-10-31 2021-08-06 朱诺治疗学有限公司 选择并刺激细胞的方法及用于所述方法的设备
CN112812176B (zh) * 2021-01-13 2022-10-11 江南大学 一种通过低盐絮凝法从螺旋藻中提取藻蓝蛋白的方法
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Also Published As

Publication number Publication date
EP2314602A1 (en) 2011-04-27
KR20060123173A (ko) 2006-12-01
CA2546157A1 (en) 2005-09-29
EP1687324A4 (en) 2007-08-22
EP1687324B1 (en) 2012-08-22
PL2327718T3 (pl) 2016-10-31
MXPA06005705A (es) 2006-08-23
WO2005089093A3 (en) 2006-03-02
CN1882605B (zh) 2012-07-11
CN1882605A (zh) 2006-12-20
AU2004317306B2 (en) 2010-09-02
JP2007512028A (ja) 2007-05-17
AU2004317306A1 (en) 2005-09-29
EP2336153A1 (en) 2011-06-22
WO2005089093A2 (en) 2005-09-29
KR101265343B1 (ko) 2013-05-20
EP2336153B1 (en) 2016-03-30
CA2546157C (en) 2014-07-22
JP5028551B2 (ja) 2012-09-19
BRPI0416807A (pt) 2007-01-09
US20060008877A1 (en) 2006-01-12
EP1687324A2 (en) 2006-08-09
EP2327718B1 (en) 2016-03-23
EP2327718A1 (en) 2011-06-01
US7985564B2 (en) 2011-07-26

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GB0314407D0 (en) The memopage
GB0322562D0 (en) The matlight
GB0306818D0 (en) The slumber-bumper
GB0313872D0 (en) The brushbox
GB0313688D0 (en) The dry-warm unbrella
GB0325666D0 (en) The femu
GB0300669D0 (en) The babybath