PL2343052T3 - Hydrofilowa filtracja podczas produkcji adiuwantów do szczepionek - Google Patents

Hydrofilowa filtracja podczas produkcji adiuwantów do szczepionek

Info

Publication number
PL2343052T3
PL2343052T3 PL10252044T PL10252044T PL2343052T3 PL 2343052 T3 PL2343052 T3 PL 2343052T3 PL 10252044 T PL10252044 T PL 10252044T PL 10252044 T PL10252044 T PL 10252044T PL 2343052 T3 PL2343052 T3 PL 2343052T3
Authority
PL
Poland
Prior art keywords
during manufacture
vaccine adjuvants
filtration during
hydrophilic filtration
hydrophilic
Prior art date
Application number
PL10252044T
Other languages
English (en)
Inventor
Gottfried Kraus
Robert Eskes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43971135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2343052(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2343052T3 publication Critical patent/PL2343052T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
    • B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
    • B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Colloid Chemistry (AREA)
PL10252044T 2009-12-03 2010-12-03 Hydrofilowa filtracja podczas produkcji adiuwantów do szczepionek PL2343052T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28351709P 2009-12-03 2009-12-03
EP10252044.2A EP2343052B1 (en) 2009-12-03 2010-12-03 Hydrophilic filtration during manufacture of vaccine adjuvants

Publications (1)

Publication Number Publication Date
PL2343052T3 true PL2343052T3 (pl) 2013-11-29

Family

ID=43971135

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10252044T PL2343052T3 (pl) 2009-12-03 2010-12-03 Hydrofilowa filtracja podczas produkcji adiuwantów do szczepionek

Country Status (21)

Country Link
US (3) US10213383B2 (pl)
EP (3) EP2601933B1 (pl)
JP (2) JP5754860B2 (pl)
KR (2) KR101625623B1 (pl)
CN (2) CN104688687A (pl)
AU (1) AU2010325748B2 (pl)
BR (1) BR112012013425A2 (pl)
CA (1) CA2780425C (pl)
CL (1) CL2012001268A1 (pl)
DK (1) DK2343052T3 (pl)
EA (1) EA025622B1 (pl)
ES (3) ES2426969T3 (pl)
HR (1) HRP20130623T1 (pl)
IL (1) IL219627B (pl)
MX (1) MX2012005598A (pl)
NZ (1) NZ599881A (pl)
PL (1) PL2343052T3 (pl)
PT (1) PT2343052E (pl)
SG (1) SG10201501612RA (pl)
SI (2) SI2506832T1 (pl)
WO (1) WO2011067669A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2343052T3 (da) 2009-12-03 2013-09-02 Novartis Ag Hydrofil filtrering under fremstilling af vaccineadjuvanter
EP2506834B1 (en) 2009-12-03 2016-03-02 Novartis AG Circulation of components during homogenization and microfluidization of emulsions
DE102009056884B4 (de) 2009-12-03 2021-03-18 Novartis Ag Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
PL2380558T5 (pl) † 2009-12-03 2020-10-05 Novartis Ag Wytwarzanie emulsji w układzie komory oddziaływań i komory przeciwciśnieniowej do mikrofluidyzacji
CL2012001399A1 (es) 2009-12-03 2013-03-08 Novartis Ag Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion.
AU2011251706B2 (en) 2010-05-12 2015-10-22 Seqirus UK Limited Improved methods for preparing squalene
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JP6345603B2 (ja) 2012-03-08 2018-06-20 ノバルティス アーゲー 追加免疫ワクチンのアジュバント化された処方物
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US20150320852A1 (en) 2012-12-18 2015-11-12 Glaxosmithkline Biologicals Sa Conjugates for protecting against diphtheria and/or tetanus
KR20170063750A (ko) 2014-09-26 2017-06-08 세퀴러스 유케이 리미티드 면역손상된 대상체의 백신 접종
KR20230154072A (ko) 2014-09-26 2023-11-07 세퀴러스 유케이 리미티드 면역손상된 대상체의 백신 접종
WO2016087479A1 (en) 2014-12-02 2016-06-09 Novartis Ag Manufacture of surfactant-containing compositions
JP6995756B2 (ja) * 2015-12-23 2022-02-04 ノバルティス アーゲー レチノイン酸を含む水中油型エマルジョン
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AU2021302954A1 (en) * 2020-06-30 2023-02-16 Seqirus UK Limited Cold filtration of oil-in-water emulsion adjuvants
CN113876943A (zh) * 2020-07-03 2022-01-04 神州细胞工程有限公司 浓缩的水包油型亚微乳佐剂及其制备方法
CN114749055A (zh) * 2022-01-18 2022-07-15 张家斌 一种疫苗制造用设备及疫苗制造工艺

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DK2343052T3 (da) 2009-12-03 2013-09-02 Novartis Ag Hydrofil filtrering under fremstilling af vaccineadjuvanter
PL2380558T5 (pl) 2009-12-03 2020-10-05 Novartis Ag Wytwarzanie emulsji w układzie komory oddziaływań i komory przeciwciśnieniowej do mikrofluidyzacji
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Also Published As

Publication number Publication date
KR101625623B1 (ko) 2016-05-31
EP2506832A2 (en) 2012-10-10
US20210077395A1 (en) 2021-03-18
DK2343052T3 (da) 2013-09-02
SI2601933T1 (sl) 2015-12-31
JP5754860B2 (ja) 2015-07-29
US20190201337A1 (en) 2019-07-04
EP2601933A1 (en) 2013-06-12
US10799454B2 (en) 2020-10-13
BR112012013425A2 (pt) 2020-11-03
ES2461852T3 (es) 2014-05-21
JP2013512890A (ja) 2013-04-18
KR20150041812A (ko) 2015-04-17
CL2012001268A1 (es) 2012-08-03
CN102858322B (zh) 2015-04-29
ES2558056T3 (es) 2016-02-01
HK1159995A1 (en) 2012-08-10
SG10201501612RA (en) 2015-04-29
AU2010325748B2 (en) 2014-04-17
US20130129786A1 (en) 2013-05-23
WO2011067669A2 (en) 2011-06-09
CA2780425A1 (en) 2011-06-09
WO2011067669A3 (en) 2011-08-04
NZ599881A (en) 2014-01-31
JP2015098499A (ja) 2015-05-28
EP2506832B1 (en) 2014-02-26
PT2343052E (pt) 2013-08-28
CA2780425C (en) 2014-02-04
AU2010325748A1 (en) 2012-05-31
IL219627B (en) 2018-05-31
EA025622B1 (ru) 2017-01-30
CN104688687A (zh) 2015-06-10
MX2012005598A (es) 2012-05-29
EP2601933B1 (en) 2015-10-07
US10213383B2 (en) 2019-02-26
HRP20130623T1 (en) 2013-09-30
EP2343052B1 (en) 2013-06-12
EP2343052A1 (en) 2011-07-13
HK1175407A1 (en) 2013-07-05
CN102858322A (zh) 2013-01-02
IL219627A0 (en) 2012-07-31
KR20120101652A (ko) 2012-09-14
EA201270519A1 (ru) 2012-12-28
ES2426969T3 (es) 2013-10-28
KR101616735B1 (ko) 2016-04-29
SI2506832T1 (sl) 2014-06-30

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