PL2350079T3 - Związki tiazolilo-pirazolopirymidynowe jako syntetyczne półprodukty i pokrewne procesy syntetyczne - Google Patents

Związki tiazolilo-pirazolopirymidynowe jako syntetyczne półprodukty i pokrewne procesy syntetyczne

Info

Publication number
PL2350079T3
PL2350079T3 PL09736733T PL09736733T PL2350079T3 PL 2350079 T3 PL2350079 T3 PL 2350079T3 PL 09736733 T PL09736733 T PL 09736733T PL 09736733 T PL09736733 T PL 09736733T PL 2350079 T3 PL2350079 T3 PL 2350079T3
Authority
PL
Poland
Prior art keywords
synthetic
thiazolyl
pyrazolopyrimidine compounds
processes
intermediates
Prior art date
Application number
PL09736733T
Other languages
English (en)
Inventor
John Robert Rizzo
Sathish Kumar Boini
Radhe Krishan Vaid
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL2350079T3 publication Critical patent/PL2350079T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL09736733T 2008-10-02 2009-09-29 Związki tiazolilo-pirazolopirymidynowe jako syntetyczne półprodukty i pokrewne procesy syntetyczne PL2350079T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10215308P 2008-10-02 2008-10-02
EP09736733A EP2350079B1 (en) 2008-10-02 2009-09-29 Thiazolyl-pyrazolopyrimidine compounds as synthetic intermediates and related synthetic processes
PCT/US2009/058722 WO2010039678A1 (en) 2008-10-02 2009-09-29 Thiazolyl-pyrazolopyrimidine compounds as synthetic intermediates and related synthetic processes

Publications (1)

Publication Number Publication Date
PL2350079T3 true PL2350079T3 (pl) 2013-03-29

Family

ID=41507435

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09736733T PL2350079T3 (pl) 2008-10-02 2009-09-29 Związki tiazolilo-pirazolopirymidynowe jako syntetyczne półprodukty i pokrewne procesy syntetyczne

Country Status (21)

Country Link
US (1) US8563718B2 (pl)
EP (1) EP2350079B1 (pl)
JP (1) JP5524221B2 (pl)
KR (1) KR101357392B1 (pl)
CN (1) CN102171212A (pl)
AR (1) AR073708A1 (pl)
AU (1) AU2009298757B2 (pl)
BR (1) BRPI0920838A2 (pl)
CA (1) CA2739422C (pl)
CY (1) CY1113499T1 (pl)
DK (1) DK2350079T3 (pl)
EA (1) EA018807B1 (pl)
ES (1) ES2397509T3 (pl)
HR (1) HRP20120961T1 (pl)
IL (1) IL211292A (pl)
MX (1) MX2011003529A (pl)
PL (1) PL2350079T3 (pl)
PT (1) PT2350079E (pl)
SI (1) SI2350079T1 (pl)
TW (1) TWI432435B (pl)
WO (1) WO2010039678A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250022913A (ko) 2017-08-14 2025-02-17 스프루스 바이오사이언시스 인코포레이티드 코티코트로핀 방출 인자 수용체 길항제
MX2019015318A (es) * 2017-08-14 2020-07-20 Spruce Biosciences Inc Antagonistas del receptor del factor liberador de corticotropina.
CN112423747A (zh) 2018-04-27 2021-02-26 云杉生物科学公司 用于治疗睾丸肾上腺残余瘤和卵巢肾上腺残余瘤的方法
MX2023001688A (es) 2020-08-12 2023-02-22 Spruce Biosciences Inc Metodos y composiciones para tratar el sindrome de ovario poliquistico.
US11708372B2 (en) 2021-11-19 2023-07-25 Spruce Biosciences, Inc. Crystalline composition of tildacerfont and methods of use and preparation thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0644762B1 (en) * 1992-06-10 1997-12-17 Fujisawa Pharmaceutical Co., Ltd. Pyrazolopyridine compounds for the treatment of anemia
UA96458C2 (ru) * 2006-09-20 2011-11-10 Эли Лилли Энд Компани Тиазолпиразолопиримидиновые соединения как антагонисты рецептора crf1
US8952207B2 (en) 2007-09-11 2015-02-10 The University Of Houston System Copper-catalyzed C—H bond arylation

Also Published As

Publication number Publication date
TWI432435B (zh) 2014-04-01
KR101357392B1 (ko) 2014-02-03
AU2009298757B2 (en) 2013-08-01
MX2011003529A (es) 2011-04-21
EA018807B1 (ru) 2013-10-30
WO2010039678A1 (en) 2010-04-08
US8563718B2 (en) 2013-10-22
TW201018692A (en) 2010-05-16
US20110166345A1 (en) 2011-07-07
AR073708A1 (es) 2010-11-24
EP2350079A1 (en) 2011-08-03
CY1113499T1 (el) 2016-06-22
IL211292A (en) 2013-06-27
CA2739422A1 (en) 2010-04-08
KR20110063513A (ko) 2011-06-10
BRPI0920838A2 (pt) 2018-10-16
PT2350079E (pt) 2012-12-20
SI2350079T1 (sl) 2013-02-28
CA2739422C (en) 2013-03-12
CN102171212A (zh) 2011-08-31
DK2350079T3 (da) 2012-12-17
JP2012504626A (ja) 2012-02-23
ES2397509T3 (es) 2013-03-07
HRP20120961T1 (hr) 2012-12-31
JP5524221B2 (ja) 2014-06-18
EA201170526A1 (ru) 2011-10-31
EP2350079B1 (en) 2012-11-14
IL211292A0 (en) 2011-04-28
AU2009298757A1 (en) 2010-04-08

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