PL2350117T3 - Pochodne peptydów i ich zastosowanie jako wektorów cząsteczek w postaci koniugatów - Google Patents

Pochodne peptydów i ich zastosowanie jako wektorów cząsteczek w postaci koniugatów

Info

Publication number
PL2350117T3
PL2350117T3 PL09760175T PL09760175T PL2350117T3 PL 2350117 T3 PL2350117 T3 PL 2350117T3 PL 09760175 T PL09760175 T PL 09760175T PL 09760175 T PL09760175 T PL 09760175T PL 2350117 T3 PL2350117 T3 PL 2350117T3
Authority
PL
Poland
Prior art keywords
conjugates
carriers
molecules
peptide derivatives
peptide
Prior art date
Application number
PL09760175T
Other languages
English (en)
Inventor
Michel Khrestchatisky
Marion David
Yves Molino
Patrick Vlieghe
Original Assignee
Vect Horus
Centre Nat Rech Scient
Univ Aix Marseille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vect Horus, Centre Nat Rech Scient, Univ Aix Marseille filed Critical Vect Horus
Publication of PL2350117T3 publication Critical patent/PL2350117T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL09760175T 2008-10-22 2009-10-20 Pochodne peptydów i ich zastosowanie jako wektorów cząsteczek w postaci koniugatów PL2350117T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0857159A FR2937322B1 (fr) 2008-10-22 2008-10-22 Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues
PCT/FR2009/051991 WO2010046588A1 (fr) 2008-10-22 2009-10-20 Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues
EP09760175.1A EP2350117B1 (fr) 2008-10-22 2009-10-20 Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues

Publications (1)

Publication Number Publication Date
PL2350117T3 true PL2350117T3 (pl) 2015-04-30

Family

ID=40852530

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09760175T PL2350117T3 (pl) 2008-10-22 2009-10-20 Pochodne peptydów i ich zastosowanie jako wektorów cząsteczek w postaci koniugatów

Country Status (16)

Country Link
US (2) US8729029B2 (pl)
EP (1) EP2350117B1 (pl)
JP (2) JP5808250B2 (pl)
CN (1) CN102282159B (pl)
AU (1) AU2009306237B2 (pl)
BR (1) BRPI0919777B1 (pl)
CA (1) CA2741098C (pl)
DK (1) DK2350117T3 (pl)
EA (1) EA022976B1 (pl)
ES (1) ES2525649T3 (pl)
FR (1) FR2937322B1 (pl)
HR (1) HRP20141139T1 (pl)
PL (1) PL2350117T3 (pl)
SI (1) SI2350117T1 (pl)
WO (1) WO2010046588A1 (pl)
ZA (1) ZA201103669B (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849257B2 (en) 2000-02-04 2005-02-01 Children's Hospital Research Foundation Lipid hydrolysis therapy for atherosclerosis and related diseases
FR2937322B1 (fr) 2008-10-22 2013-02-22 Vect Horus Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues
FR2959229B1 (fr) 2010-04-21 2013-01-18 Vect Horus Derives peptidiques, leur preparation et leurs utilisations
WO2014060601A1 (en) 2012-10-19 2014-04-24 Vect-Horus Compositions and methods for drug delivery
FI3205351T3 (fi) 2010-04-23 2023-07-06 Alexion Pharma Inc Lysosomaalisen kertymätaudin entsyymi
KR20150038636A (ko) 2010-09-09 2015-04-08 시나게바 바이오파르마, 코포레이션 환자에서 리소좀 산 리파제 결핍증의 치료를 위한 리소좀 산 리파제의 용도
WO2012112681A1 (en) 2011-02-15 2012-08-23 Shire Human Genetic Therapies, Inc. Methods for treating lysosomal acid lipase deficiency
CN104117069A (zh) * 2013-04-26 2014-10-29 复旦大学 一种针对脑胶质瘤的靶向纳米递药系统及其制备方法和应用
US20150093399A1 (en) 2013-08-28 2015-04-02 Bioasis Technologies, Inc. Cns-targeted conjugates having modified fc regions and methods of use thereof
EP2896402A1 (en) * 2014-01-20 2015-07-22 Vect-Horus Activated neurotensin molecules and the uses thereof
WO2018118015A1 (en) 2016-12-19 2018-06-28 Morehouse School Of Medicine Compositions and methods for treating diseases by inhibiting exosome release
WO2018138372A1 (en) * 2017-01-30 2018-08-02 Vect-Horus Compositions and methods for cancer imaging and radiotherapy
US10688191B2 (en) 2018-01-19 2020-06-23 Hr Biomed, Llc Delivery of a chemotherapy agent across the blood-brain barrier
CA3124790A1 (en) 2019-01-09 2020-07-16 Vect-Horus Transferrin receptor-binding molecules, conjugates thereof and their uses
WO2021116079A1 (en) 2019-12-10 2021-06-17 Université de Mons Peptides binding to ldl-receptor as carriers for crossing the blood brain barrier
CA3128035A1 (en) 2020-08-13 2022-02-13 Bioasis Technologies, Inc. Combination therapies for delivery across the blood brain barrier
US20260022187A1 (en) * 2022-07-28 2026-01-22 Ohio State Innovation Foundation Methods and compositions regarding cyclic peptides for use with antibodies and antibody fragments
WO2024228936A1 (en) * 2023-05-03 2024-11-07 Merck Sharp & Dohme Llc Cyclic peptides as pet imaging agents of granzyme b
EP4731658A1 (en) 2023-06-22 2026-04-29 Vect-Horus Transferrin receptor-binding molecules, conjugates thereof and their uses to prevent or treat nervous system diseases
EP4480965A1 (en) 2023-06-22 2024-12-25 Vect-Horus Transferrin receptor-binding molecules, conjugates thereof and their uses to prevent or treat cns diseases
WO2025193680A1 (en) * 2024-03-11 2025-09-18 Ohio State Innovation Foundation Disulfide cyclic cell-penetrating peptides and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981478A (en) * 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
US6232287B1 (en) * 1998-03-13 2001-05-15 The Burnham Institute Molecules that home to various selected organs or tissues
WO1999047566A1 (en) * 1998-03-17 1999-09-23 The Uab Research Foundation Synthetic peptides that enhance ldl uptake
WO2001047944A2 (en) * 1999-12-28 2001-07-05 Curagen Corporation Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
US20110131679A2 (en) 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
JP2004520803A (ja) 2000-04-21 2004-07-15 コリクサ コーポレイション 尋常性挫瘡の治療および診断のための組成物および方法
NO20026285D0 (no) * 2002-12-30 2002-12-30 Amersham Health As Nye peptider
US20050058603A1 (en) * 2003-05-02 2005-03-17 Case Western Reserve University Drug delivery system based on polymer nanoshells
AU2003286870A1 (en) 2003-06-05 2005-01-04 Salk Institute For Biological Studies Targeting polypeptides to the central nervous system
US7723474B2 (en) * 2003-10-21 2010-05-25 The Regents Of The University Of California Molecules that selectively home to vasculature of pre-malignant dysplastic lesions or malignancies
GB0404374D0 (en) * 2004-02-27 2004-03-31 Univ Manchester Treatment of bacterial infections
FR2889532B1 (fr) 2005-08-03 2007-10-12 Lab Francais Du Fractionnement Anticorps diriges contre le recepteur du ldl
WO2007145659A1 (en) * 2005-11-10 2007-12-21 The Regents Of The University Of California Synthetic ldl as targeted drug delivery vehicle
FR2937322B1 (fr) 2008-10-22 2013-02-22 Vect Horus Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues
FR2959229B1 (fr) 2010-04-21 2013-01-18 Vect Horus Derives peptidiques, leur preparation et leurs utilisations

Also Published As

Publication number Publication date
EA201170587A1 (ru) 2012-05-30
BRPI0919777A2 (pt) 2016-09-20
US8729029B2 (en) 2014-05-20
JP5808250B2 (ja) 2015-11-10
DK2350117T3 (en) 2014-12-08
US20110230416A1 (en) 2011-09-22
AU2009306237A1 (en) 2010-04-29
US9328143B2 (en) 2016-05-03
JP6232396B2 (ja) 2017-11-15
CA2741098A1 (fr) 2010-04-29
FR2937322B1 (fr) 2013-02-22
FR2937322A1 (fr) 2010-04-23
WO2010046588A1 (fr) 2010-04-29
EP2350117A1 (fr) 2011-08-03
AU2009306237B2 (en) 2015-04-09
BRPI0919777B1 (pt) 2021-09-14
CA2741098C (fr) 2017-03-28
CN102282159A (zh) 2011-12-14
US20140243499A1 (en) 2014-08-28
EA022976B1 (ru) 2016-04-29
CN102282159B (zh) 2015-11-25
JP2015212264A (ja) 2015-11-26
ZA201103669B (en) 2012-01-25
SI2350117T1 (sl) 2015-03-31
HRP20141139T1 (en) 2015-03-13
JP2012506407A (ja) 2012-03-15
ES2525649T3 (es) 2014-12-26
EP2350117B1 (fr) 2014-09-10
WO2010046588A9 (fr) 2010-06-24

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