BRPI0919777A2 - derivados de peptídeo e uso dos mesmos como vetores para moléculas na forma de conjugados - Google Patents
derivados de peptídeo e uso dos mesmos como vetores para moléculas na forma de conjugadosInfo
- Publication number
- BRPI0919777A2 BRPI0919777A2 BRPI0919777A BRPI0919777A BRPI0919777A2 BR PI0919777 A2 BRPI0919777 A2 BR PI0919777A2 BR PI0919777 A BRPI0919777 A BR PI0919777A BR PI0919777 A BRPI0919777 A BR PI0919777A BR PI0919777 A2 BRPI0919777 A2 BR PI0919777A2
- Authority
- BR
- Brazil
- Prior art keywords
- conjugates
- vectors
- molecules
- peptide derivatives
- peptide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0857159A FR2937322B1 (fr) | 2008-10-22 | 2008-10-22 | Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues |
| FR0857159 | 2008-10-22 | ||
| PCT/FR2009/051991 WO2010046588A1 (fr) | 2008-10-22 | 2009-10-20 | Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0919777A2 true BRPI0919777A2 (pt) | 2016-09-20 |
| BRPI0919777B1 BRPI0919777B1 (pt) | 2021-09-14 |
Family
ID=40852530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0919777-0A BRPI0919777B1 (pt) | 2008-10-22 | 2009-10-20 | Derivados de peptídeo e uso dos mesmos como vetores para moléculas na forma de conjugados |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8729029B2 (pt) |
| EP (1) | EP2350117B1 (pt) |
| JP (2) | JP5808250B2 (pt) |
| CN (1) | CN102282159B (pt) |
| AU (1) | AU2009306237B2 (pt) |
| BR (1) | BRPI0919777B1 (pt) |
| CA (1) | CA2741098C (pt) |
| DK (1) | DK2350117T3 (pt) |
| EA (1) | EA022976B1 (pt) |
| ES (1) | ES2525649T3 (pt) |
| FR (1) | FR2937322B1 (pt) |
| HR (1) | HRP20141139T1 (pt) |
| PL (1) | PL2350117T3 (pt) |
| SI (1) | SI2350117T1 (pt) |
| WO (1) | WO2010046588A1 (pt) |
| ZA (1) | ZA201103669B (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2328446T5 (es) | 2000-02-04 | 2014-02-27 | Children's Hospital Research Foundation | Uso de lipasa ácida lisosomal para tratar la aterosclerosis y enfermedades asociadas |
| FR2937322B1 (fr) * | 2008-10-22 | 2013-02-22 | Vect Horus | Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues |
| FR2959229B1 (fr) * | 2010-04-21 | 2013-01-18 | Vect Horus | Derives peptidiques, leur preparation et leurs utilisations |
| PT2561069T (pt) | 2010-04-23 | 2017-05-22 | Alexion Pharma Inc | Enzima de doença de armazenamento lisossomal |
| CA2810999C (en) | 2010-09-09 | 2023-10-03 | Anthony Quinn | Use of lysosomal acid lipase for treating lysosomal acid lipase deficiency in patients |
| EP2675472A4 (en) | 2011-02-15 | 2014-09-17 | Synageva Biopharma Corp | METHOD FOR THE TREATMENT OF LACK OF LYSOSOMAL SAURER LIPASE |
| EP2908837B1 (en) | 2012-10-19 | 2019-02-13 | Vect-Horus | Compositions for drug delivery |
| CN104117069A (zh) * | 2013-04-26 | 2014-10-29 | 复旦大学 | 一种针对脑胶质瘤的靶向纳米递药系统及其制备方法和应用 |
| US20150093399A1 (en) | 2013-08-28 | 2015-04-02 | Bioasis Technologies, Inc. | Cns-targeted conjugates having modified fc regions and methods of use thereof |
| EP2896402A1 (en) | 2014-01-20 | 2015-07-22 | Vect-Horus | Activated neurotensin molecules and the uses thereof |
| EP3554638B1 (en) | 2016-12-19 | 2022-02-02 | Morehouse School of Medicine | Compositions and methods for treating diseases by inhibiting exosome release |
| JP2020506921A (ja) | 2017-01-30 | 2020-03-05 | ヴェクト−オールVect−Horus | がんイメージング及びがん放射線治療のための組成物及び方法 |
| US10688191B2 (en) | 2018-01-19 | 2020-06-23 | Hr Biomed, Llc | Delivery of a chemotherapy agent across the blood-brain barrier |
| CA3124790A1 (en) | 2019-01-09 | 2020-07-16 | Vect-Horus | Transferrin receptor-binding molecules, conjugates thereof and their uses |
| WO2021116079A1 (en) | 2019-12-10 | 2021-06-17 | Université de Mons | Peptides binding to ldl-receptor as carriers for crossing the blood brain barrier |
| EP3954393A1 (en) | 2020-08-13 | 2022-02-16 | Bioasis Technologies Inc. | Combination therapies for delivery across the blood brain barrier |
| US20260022187A1 (en) * | 2022-07-28 | 2026-01-22 | Ohio State Innovation Foundation | Methods and compositions regarding cyclic peptides for use with antibodies and antibody fragments |
| EP4705315A1 (en) * | 2023-05-03 | 2026-03-11 | Merck Sharp & Dohme LLC | Cyclic peptides as pet imaging agents of granzyme b |
| AU2024313677A1 (en) | 2023-06-22 | 2026-01-08 | Centre National De La Recherche Scientifique | Transferrin receptor-binding molecules, conjugates thereof and their uses to prevent or treat nervous system diseases |
| EP4480965A1 (en) | 2023-06-22 | 2024-12-25 | Vect-Horus | Transferrin receptor-binding molecules, conjugates thereof and their uses to prevent or treat cns diseases |
| WO2025193680A1 (en) * | 2024-03-11 | 2025-09-18 | Ohio State Innovation Foundation | Disulfide cyclic cell-penetrating peptides and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981478A (en) * | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US6232287B1 (en) * | 1998-03-13 | 2001-05-15 | The Burnham Institute | Molecules that home to various selected organs or tissues |
| WO1999047566A1 (en) * | 1998-03-17 | 1999-09-23 | The Uab Research Foundation | Synthetic peptides that enhance ldl uptake |
| AU2914501A (en) * | 1999-12-28 | 2001-07-09 | Curagen Corporation | Nucleic acids containing single nucleotide polymorphisms and methods of use thereof |
| US20110131679A2 (en) | 2000-04-19 | 2011-06-02 | Thomas La Rosa | Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
| CA2407352A1 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
| NO20026285D0 (no) * | 2002-12-30 | 2002-12-30 | Amersham Health As | Nye peptider |
| WO2005044224A2 (en) * | 2003-05-02 | 2005-05-19 | Case Western Reserve University | Drug delivery system based on polymer nanoshells |
| WO2004108071A2 (en) | 2003-06-05 | 2004-12-16 | Salk Institute For Biological Studies | Targeting polypeptides to the central nervous system |
| US7723474B2 (en) * | 2003-10-21 | 2010-05-25 | The Regents Of The University Of California | Molecules that selectively home to vasculature of pre-malignant dysplastic lesions or malignancies |
| GB0404374D0 (en) * | 2004-02-27 | 2004-03-31 | Univ Manchester | Treatment of bacterial infections |
| FR2889532B1 (fr) | 2005-08-03 | 2007-10-12 | Lab Francais Du Fractionnement | Anticorps diriges contre le recepteur du ldl |
| US8252338B2 (en) * | 2005-11-10 | 2012-08-28 | The Regents Of The University Of California | Synthetic LDL as targeted drug delivery vehicle |
| FR2937322B1 (fr) | 2008-10-22 | 2013-02-22 | Vect Horus | Derives peptidiques et leur utilisation comme vecteurs de molecules sous forme de conjugues |
| FR2959229B1 (fr) | 2010-04-21 | 2013-01-18 | Vect Horus | Derives peptidiques, leur preparation et leurs utilisations |
-
2008
- 2008-10-22 FR FR0857159A patent/FR2937322B1/fr active Active
-
2009
- 2009-10-20 AU AU2009306237A patent/AU2009306237B2/en active Active
- 2009-10-20 EP EP09760175.1A patent/EP2350117B1/fr active Active
- 2009-10-20 PL PL09760175T patent/PL2350117T3/pl unknown
- 2009-10-20 WO PCT/FR2009/051991 patent/WO2010046588A1/fr not_active Ceased
- 2009-10-20 CA CA2741098A patent/CA2741098C/fr active Active
- 2009-10-20 BR BRPI0919777-0A patent/BRPI0919777B1/pt active IP Right Grant
- 2009-10-20 SI SI200931072T patent/SI2350117T1/sl unknown
- 2009-10-20 ES ES09760175.1T patent/ES2525649T3/es active Active
- 2009-10-20 CN CN200980150257.2A patent/CN102282159B/zh active Active
- 2009-10-20 US US13/125,634 patent/US8729029B2/en active Active
- 2009-10-20 JP JP2011532687A patent/JP5808250B2/ja active Active
- 2009-10-20 EA EA201170587A patent/EA022976B1/ru not_active IP Right Cessation
- 2009-10-20 HR HRP20141139AT patent/HRP20141139T1/hr unknown
- 2009-10-20 DK DK09760175.1T patent/DK2350117T3/en active
-
2011
- 2011-05-19 ZA ZA2011/03669A patent/ZA201103669B/en unknown
-
2014
- 2014-05-14 US US14/277,339 patent/US9328143B2/en active Active
-
2015
- 2015-05-27 JP JP2015107552A patent/JP6232396B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012506407A (ja) | 2012-03-15 |
| US8729029B2 (en) | 2014-05-20 |
| CN102282159B (zh) | 2015-11-25 |
| CA2741098C (fr) | 2017-03-28 |
| US20140243499A1 (en) | 2014-08-28 |
| US20110230416A1 (en) | 2011-09-22 |
| ZA201103669B (en) | 2012-01-25 |
| WO2010046588A9 (fr) | 2010-06-24 |
| EA201170587A1 (ru) | 2012-05-30 |
| DK2350117T3 (en) | 2014-12-08 |
| JP6232396B2 (ja) | 2017-11-15 |
| FR2937322B1 (fr) | 2013-02-22 |
| CN102282159A (zh) | 2011-12-14 |
| PL2350117T3 (pl) | 2015-04-30 |
| SI2350117T1 (sl) | 2015-03-31 |
| EP2350117A1 (fr) | 2011-08-03 |
| JP5808250B2 (ja) | 2015-11-10 |
| AU2009306237B2 (en) | 2015-04-09 |
| WO2010046588A1 (fr) | 2010-04-29 |
| EP2350117B1 (fr) | 2014-09-10 |
| US9328143B2 (en) | 2016-05-03 |
| ES2525649T3 (es) | 2014-12-26 |
| AU2009306237A1 (en) | 2010-04-29 |
| EA022976B1 (ru) | 2016-04-29 |
| BRPI0919777B1 (pt) | 2021-09-14 |
| HRP20141139T1 (en) | 2015-03-13 |
| JP2015212264A (ja) | 2015-11-26 |
| FR2937322A1 (fr) | 2010-04-23 |
| CA2741098A1 (fr) | 2010-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: UNIVERSITE D'AIX - MARSEILLE (FR) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/10/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |