PL2363392T3 - Styrylopirydynowe pochodne i ich zastosowanie do wiązania i obrazowania płytek amyloidowych - Google Patents

Styrylopirydynowe pochodne i ich zastosowanie do wiązania i obrazowania płytek amyloidowych

Info

Publication number
PL2363392T3
PL2363392T3 PL11152124T PL11152124T PL2363392T3 PL 2363392 T3 PL2363392 T3 PL 2363392T3 PL 11152124 T PL11152124 T PL 11152124T PL 11152124 T PL11152124 T PL 11152124T PL 2363392 T3 PL2363392 T3 PL 2363392T3
Authority
PL
Poland
Prior art keywords
binding
amyloid plaques
styrylpyridine
imaging amyloid
compounds
Prior art date
Application number
PL11152124T
Other languages
English (en)
Inventor
Hank F Kung
Mei-Ping Kung
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of PL2363392T3 publication Critical patent/PL2363392T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11152124T 2006-03-30 2007-03-26 Styrylopirydynowe pochodne i ich zastosowanie do wiązania i obrazowania płytek amyloidowych PL2363392T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78715606P 2006-03-30 2006-03-30
EP11152124.1A EP2363392B1 (en) 2006-03-30 2007-03-26 Styrylpyridine derivatives and their use for binding and imaging amyloid plaques
EP07753982A EP1999109B1 (en) 2006-03-30 2007-03-26 Styrylpyridine derivatives and their use for binding and imaging amyloid plaques

Publications (1)

Publication Number Publication Date
PL2363392T3 true PL2363392T3 (pl) 2017-10-31

Family

ID=38326579

Family Applications (2)

Application Number Title Priority Date Filing Date
PL07753982T PL1999109T3 (pl) 2006-03-30 2007-03-26 Pochodne styrylopirydyny i ich zastosowanie do wiązania i obrazowania blaszek amyloidowych
PL11152124T PL2363392T3 (pl) 2006-03-30 2007-03-26 Styrylopirydynowe pochodne i ich zastosowanie do wiązania i obrazowania płytek amyloidowych

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL07753982T PL1999109T3 (pl) 2006-03-30 2007-03-26 Pochodne styrylopirydyny i ich zastosowanie do wiązania i obrazowania blaszek amyloidowych

Country Status (34)

Country Link
US (3) US7687052B2 (pl)
EP (3) EP2363391A1 (pl)
JP (1) JP5290954B2 (pl)
KR (1) KR101376807B1 (pl)
CN (1) CN101522624B (pl)
AT (1) ATE539060T1 (pl)
AU (1) AU2007243712B2 (pl)
BR (1) BRPI0710225B1 (pl)
CA (1) CA2644530C (pl)
CR (1) CR10329A (pl)
CY (3) CY1113048T1 (pl)
DK (2) DK2363392T3 (pl)
EA (1) EA017898B1 (pl)
EC (1) ECSP088783A (pl)
ES (2) ES2378785T3 (pl)
FR (1) FR13C0034I2 (pl)
GT (1) GT200800201A (pl)
HR (2) HRP20120135T1 (pl)
HU (2) HUE032660T2 (pl)
IL (1) IL193567A (pl)
LT (1) LT2363392T (pl)
LU (1) LU92232I2 (pl)
MX (1) MX2008012527A (pl)
NO (2) NO342090B1 (pl)
NZ (1) NZ570887A (pl)
PL (2) PL1999109T3 (pl)
PT (2) PT2363392T (pl)
RS (2) RS56171B1 (pl)
SG (1) SG173338A1 (pl)
SI (2) SI2363392T1 (pl)
TW (1) TWI399366B (pl)
UA (1) UA97802C2 (pl)
WO (1) WO2007126733A2 (pl)
ZA (1) ZA200807955B (pl)

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UA97802C2 (uk) 2006-03-30 2012-03-26 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания Стирилпіридинові похідні і їх застосування для зв'язування і візуалізації амілоїдних бляшок
WO2009004914A1 (ja) * 2007-07-04 2009-01-08 Tohoku University フッ素およびヒドロキシ基で置換されたアルコキシ基を有するｐｅｔプローブ
US8557222B2 (en) * 2008-04-04 2013-10-15 Avid Radiopharmaceuticals, Inc. Radiopharmaceutical imaging of neurodegenerative diseases
CN102271716B (zh) * 2008-12-31 2014-11-19 阿维德放射性药品公司 由甲苯磺酸酯前体合成18f-放射性标记的苯乙烯基吡啶及其稳定的药物组合物
US8968701B2 (en) * 2009-07-10 2015-03-03 Piramal Imaging Sa Usage of low to medium-pressure liquid chromatography for the purification of radiotracers
WO2011045415A2 (en) 2009-10-15 2011-04-21 Guerbet New imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases
BR112012015369A2 (pt) * 2009-12-23 2018-01-23 Piramal Imaging Sa formulacões adequadas para realização de imagens de pet com agentes pet hidrofóbicos
WO2011141515A1 (en) 2010-05-14 2011-11-17 Bayer Pharma Aktiengesellschaft Diagnostic agents for amyloid beta imaging
MX2012014115A (es) 2010-06-04 2013-07-03 Piramal Imaging Sa Metodo para la produccion de ligandos beta amiloide marcados con 18f.
TWI504414B (zh) 2010-06-04 2015-10-21 Bayer Schering Pharma Ag 生產Ｆ－１８標記之Ａβ配位體之方法
US20130209363A1 (en) 2010-06-04 2013-08-15 Piramal Imaging Sa Method for production of f-18 labeled amyloid beta ligands
AU2011260419A1 (en) * 2010-06-04 2012-12-20 Piramal Imaging Sa Method for production of F-18 labeled amyloid beta ligands
CN101891674B (zh) * 2010-06-24 2012-11-14 山东大学 4-苯乙烯基吡啶类化合物及其制备方法与应用
US9259495B2 (en) * 2010-10-12 2016-02-16 Mayo Foundation For Medical Education And Research Imaging of meningiomas using phenylbenzothiazole, stilbene, or biphenylalkyne derivatives
US20140079635A1 (en) * 2011-03-30 2014-03-20 Case Western Reserve University Molecular probes for detecting lipid composition
WO2012145169A2 (en) 2011-04-21 2012-10-26 The Regents Of The University Of California Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
JP2015501305A (ja) 2011-10-19 2015-01-15 ピラマル イメージング ソシエテ アノニム Ｆ‐１８標識Ａβリガンドの改良された製造方法
PT2836241T (pt) 2012-04-10 2019-05-30 Lantheus Medical Imaging Inc Métodos de síntese de radiofármacos
JP6099045B2 (ja) * 2013-04-30 2017-03-22 国立大学法人京都大学 トリアゾロピリミジン誘導体化合物
JP6041751B2 (ja) * 2013-05-07 2016-12-14 日本メジフィジックス株式会社 スチリルピリジン誘導体化合物
JP2014218454A (ja) * 2013-05-07 2014-11-20 日本メジフィジックス株式会社 スチリルピリジン誘導体化合物
CN103645254B (zh) * 2013-11-28 2015-01-07 江苏省原子医学研究所 一种Aβ斑块显像剂前体AV45的含量分析方法
MX384604B (es) * 2014-05-13 2025-03-14 Hoffmann La Roche Compuestos heterocíclicos deuterados y su uso como agentes formadores de imágenes.
US10478513B2 (en) 2015-08-18 2019-11-19 The Regents Of The University Of Califonia Nitroxide containing amyloid binding agents for imaging and therapeutic uses
US10300155B2 (en) 2015-12-31 2019-05-28 Washington University Alpha-synuclein ligands
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
CN108299287A (zh) * 2018-01-02 2018-07-20 北京师范大学 与Aβ斑块具有高亲和力的N2S2类吡啶基苯乙烯化合物
CN114805190A (zh) * 2022-06-08 2022-07-29 吉林大学第一医院 一种甲基苯胺类Aβ蛋白显像剂的双柱合成方法
EP4619384A1 (en) 2022-11-14 2025-09-24 Eli Lilly and Company Polymorphic forms of florbetapir precursor av-105

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US8007954B2 (en) 2000-11-09 2011-08-30 The Trustees Of The University Of Pennsylvania Use of sulfur-containing fuels for direct oxidation fuel cells
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AU2002323417B2 (en) * 2001-08-27 2008-05-15 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
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US7807135B2 (en) * 2004-12-17 2010-10-05 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
US7858072B2 (en) * 2004-12-17 2010-12-28 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
US20070031328A1 (en) * 2005-06-24 2007-02-08 Kung Hank F Radiolabeled-pegylation of ligands for use as imaging agents
UA97802C2 (uk) * 2006-03-30 2012-03-26 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания Стирилпіридинові похідні і їх застосування для зв'язування і візуалізації амілоїдних бляшок
US20080253967A1 (en) * 2007-04-13 2008-10-16 Kung Hank F Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques

Also Published As

Publication number Publication date
US20080038195A1 (en) 2008-02-14
EP1999109B1 (en) 2011-12-28
EA200870389A1 (ru) 2009-04-28
LU92232I9 (pl) 2019-01-15
DK2363392T3 (en) 2017-07-03
ES2628882T3 (es) 2017-08-04
CA2644530A1 (en) 2007-11-08
US8840866B2 (en) 2014-09-23
CY2013024I1 (el) 2015-11-04
TW200838852A (en) 2008-10-01
JP5290954B2 (ja) 2013-09-18
UA97802C2 (uk) 2012-03-26
FR13C0034I1 (pl) 2013-08-09
HUS1300028I1 (hu) 2017-08-28
KR20080106564A (ko) 2008-12-08
EP2363392A1 (en) 2011-09-07
SG173338A1 (en) 2011-08-29
EP2363391A1 (en) 2011-09-07
CY1113048T1 (el) 2015-11-04
LU92232I2 (fr) 2013-08-26
PL1999109T3 (pl) 2012-05-31
PT2363392T (pt) 2017-06-15
GT200800201A (es) 2009-08-20
HRP20170857T1 (hr) 2017-12-01
FR13C0034I2 (fr) 2014-03-07
CY2013024I2 (el) 2015-11-04
CA2644530C (en) 2015-05-19
BRPI0710225A2 (pt) 2011-08-02
NO342090B1 (no) 2018-03-19
US8506929B2 (en) 2013-08-13
NO2018030I1 (no) 2018-09-11
PT1999109E (pt) 2012-03-16
SI1999109T1 (sl) 2012-04-30
RS56171B1 (sr) 2017-11-30
MX2008012527A (es) 2008-10-14
CN101522624B (zh) 2013-11-06
CY1119048T1 (el) 2018-01-10
IL193567A (en) 2014-03-31
SI2363392T1 (sl) 2017-09-29
ZA200807955B (en) 2012-11-28
EP1999109A2 (en) 2008-12-10
TWI399366B (zh) 2013-06-21
IL193567A0 (en) 2009-05-04
CR10329A (es) 2008-10-29
AU2007243712A1 (en) 2007-11-08
US20090123369A1 (en) 2009-05-14
ES2378785T3 (es) 2012-04-17
AU2007243712B2 (en) 2013-01-10
CN101522624A (zh) 2009-09-02
HRP20120135T1 (hr) 2012-03-31
ECSP088783A (es) 2008-10-31
RS52222B (sr) 2012-10-31
WO2007126733A2 (en) 2007-11-08
DK1999109T3 (da) 2012-04-02
WO2007126733A3 (en) 2008-03-06
HUE032660T2 (en) 2017-10-30
JP2009532349A (ja) 2009-09-10
US20130129624A1 (en) 2013-05-23
NZ570887A (en) 2011-05-27
US7687052B2 (en) 2010-03-30
EA017898B1 (ru) 2013-04-30
EP2363392B1 (en) 2017-05-03
KR101376807B1 (ko) 2014-03-20
NO20084590L (no) 2008-12-29
BRPI0710225B1 (pt) 2021-07-13
ATE539060T1 (de) 2012-01-15
LT2363392T (lt) 2017-07-25

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