PL2379580T3 - Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi - Google Patents

Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi

Info

Publication number
PL2379580T3
PL2379580T3 PL09795876T PL09795876T PL2379580T3 PL 2379580 T3 PL2379580 T3 PL 2379580T3 PL 09795876 T PL09795876 T PL 09795876T PL 09795876 T PL09795876 T PL 09795876T PL 2379580 T3 PL2379580 T3 PL 2379580T3
Authority
PL
Poland
Prior art keywords
treatment
antibacterial agents
gram positive
novel antibacterial
positive infections
Prior art date
Application number
PL09795876T
Other languages
English (en)
Inventor
Andre Lee Pearson
Chester A Metcalf Iii
Jing Li
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PL2379580T3 publication Critical patent/PL2379580T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL09795876T 2008-12-22 2009-12-18 Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi PL2379580T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13987508P 2008-12-22 2008-12-22
PCT/US2009/068747 WO2010075215A1 (en) 2008-12-22 2009-12-18 Novel antibacterial agents for the treatment of gram positive infections
EP09795876.3A EP2379580B1 (en) 2008-12-22 2009-12-18 Novel antibacterial agents for the treatment of gram positive infections

Publications (1)

Publication Number Publication Date
PL2379580T3 true PL2379580T3 (pl) 2014-05-30

Family

ID=41718893

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09795876T PL2379580T3 (pl) 2008-12-22 2009-12-18 Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi

Country Status (26)

Country Link
US (3) US8507647B2 (pl)
EP (2) EP2674437A1 (pl)
JP (1) JP5670914B2 (pl)
KR (1) KR101717795B1 (pl)
CN (1) CN102325787B (pl)
AR (1) AR074833A1 (pl)
AU (1) AU2009330245C1 (pl)
BR (1) BRPI0923567A2 (pl)
CA (1) CA2747965C (pl)
CY (1) CY1114883T1 (pl)
DK (1) DK2379580T3 (pl)
ES (1) ES2442167T3 (pl)
HR (1) HRP20131170T1 (pl)
IL (1) IL213638A0 (pl)
MX (1) MX2011006803A (pl)
NZ (1) NZ594019A (pl)
PL (1) PL2379580T3 (pl)
PT (1) PT2379580E (pl)
RS (1) RS53152B (pl)
RU (1) RU2512396C2 (pl)
SG (1) SG172299A1 (pl)
SI (1) SI2379580T1 (pl)
SM (1) SMT201400037B (pl)
TW (1) TWI444198B (pl)
WO (1) WO2010075215A1 (pl)
ZA (1) ZA201104693B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2013157188A (ru) * 2011-05-26 2015-07-10 Кьюбист Фармасьютикалз, Инк. Композиции св-183,315 и относящиеся к ним способы
US10377699B2 (en) * 2013-11-06 2019-08-13 The University Of Hong Kong Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue
WO2015172047A1 (en) * 2014-05-08 2015-11-12 Merck Sharp & Dohme Corp. Cyclic peptide compounds and related methods, salts and compositions
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) * 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
AU2017252222B2 (en) * 2016-04-22 2019-11-07 Astrazeneca Ab Macrocyclic Mcl-1 inhibitors for treating cancer
US10098890B2 (en) 2016-10-29 2018-10-16 Cipla Limited Stable carfilzomib formulations
IT201600127655A1 (it) * 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

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USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32455E (en) * 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
DE3376424D1 (en) 1982-02-27 1988-06-01 Beecham Group Plc Antibacterial 1-normon-2-yl-heterocyclic compounds
US4399067A (en) * 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) * 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
USRE32310E (en) * 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4396543A (en) * 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4524135A (en) * 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
IL68700A0 (en) 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4452775A (en) 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
AU4837785A (en) 1984-10-09 1986-04-17 Eli Lilly And Company Process for the production of a-21978c derivatives
ZA883887B (en) * 1987-06-10 1990-02-28 Lilly Co Eli Chromatographic purification process
US5039660A (en) 1988-03-02 1991-08-13 Endocon, Inc. Partially fused peptide pellet
ATE140728T1 (de) * 1990-06-07 1996-08-15 Lilly Co Eli Lipopeptid deacylase
AU7497594A (en) 1993-08-13 1995-03-14 Smithkline Beecham Plc Derivatives of monic acids a and c having antibacterial, antimycoplasmatical, antifungal and herbicidal activity
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
ATE544851T1 (de) 1996-03-08 2012-02-15 Astellas Pharma Inc Verfahren zur deacylierung von zyklischen lipopeptiden
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
DE69930758T2 (de) 1998-09-25 2007-04-26 Cubist Pharmaceuticals, Inc., Lexington Verwendung von daptomycin
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KR20020063230A (ko) * 1999-12-15 2002-08-01 큐비스트 파마슈티컬즈 인코포레이티드 항균제로서의 신규한 리포펩티드
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
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EP1814588A2 (en) * 2004-11-12 2007-08-08 Cubist Pharmaceuticals, Inc. Antiinfective lipopeptides

Also Published As

Publication number Publication date
BRPI0923567A2 (pt) 2016-09-27
NZ594019A (en) 2013-08-30
EP2674437A1 (en) 2013-12-18
EP2379580B1 (en) 2013-10-23
TW201028161A (en) 2010-08-01
EP2379580A1 (en) 2011-10-26
CN102325787A (zh) 2012-01-18
RU2512396C2 (ru) 2014-04-10
CY1114883T1 (el) 2016-12-14
CN102325787B (zh) 2014-05-28
DK2379580T3 (da) 2014-01-20
AU2009330245A1 (en) 2011-08-04
US20140073558A1 (en) 2014-03-13
US8507647B2 (en) 2013-08-13
HRP20131170T1 (hr) 2014-01-03
IL213638A0 (en) 2011-07-31
JP2012513467A (ja) 2012-06-14
ES2442167T3 (es) 2014-02-10
KR101717795B1 (ko) 2017-03-17
CA2747965A1 (en) 2010-07-01
AU2009330245B2 (en) 2013-05-02
KR20110114592A (ko) 2011-10-19
CA2747965C (en) 2017-06-27
AR074833A1 (es) 2011-02-16
US20150337013A1 (en) 2015-11-26
RU2011130278A (ru) 2013-01-27
AU2009330245C1 (en) 2013-09-26
SG172299A1 (en) 2011-07-28
SI2379580T1 (sl) 2014-02-28
JP5670914B2 (ja) 2015-02-18
US20100184649A1 (en) 2010-07-22
RS53152B (sr) 2014-06-30
ZA201104693B (en) 2013-01-30
WO2010075215A1 (en) 2010-07-01
HK1161886A1 (en) 2012-08-10
TWI444198B (zh) 2014-07-11
MX2011006803A (es) 2011-09-06
PT2379580E (pt) 2014-01-20
SMT201400037B (it) 2014-05-07

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