PL2408799T3 - Nowa krystaliczna postać anty-progesteronu CDB-4124 - Google Patents

Nowa krystaliczna postać anty-progesteronu CDB-4124

Info

Publication number
PL2408799T3
PL2408799T3 PL10714358T PL10714358T PL2408799T3 PL 2408799 T3 PL2408799 T3 PL 2408799T3 PL 10714358 T PL10714358 T PL 10714358T PL 10714358 T PL10714358 T PL 10714358T PL 2408799 T3 PL2408799 T3 PL 2408799T3
Authority
PL
Poland
Prior art keywords
antiprogestin
cdb
crystalline form
novel crystalline
novel
Prior art date
Application number
PL10714358T
Other languages
English (en)
Inventor
Csaba Sánta
Ádám Demeter
Balázs HAVASI
Sándor Mahó
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of PL2408799T3 publication Critical patent/PL2408799T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL10714358T 2009-03-20 2010-03-22 Nowa krystaliczna postać anty-progesteronu CDB-4124 PL2408799T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0900171A HUP0900171A2 (hu) 2009-03-20 2009-03-20 17-acetoxi-11ß-[4-(dimetil-amino)-fenil]-21-metoxi-19-norpregna-4,9-dién-3,20-dion új kristályos módosulata és eljárás elõállítására
EP10714358.8A EP2408799B1 (en) 2009-03-20 2010-03-22 Novel crystalline form of antiprogestin cdb-4124
PCT/HU2010/000030 WO2010106383A1 (en) 2009-03-20 2010-03-22 Novel crystalline form of antiprogestin cdb-4124

Publications (1)

Publication Number Publication Date
PL2408799T3 true PL2408799T3 (pl) 2015-12-31

Family

ID=89988855

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10714358T PL2408799T3 (pl) 2009-03-20 2010-03-22 Nowa krystaliczna postać anty-progesteronu CDB-4124

Country Status (6)

Country Link
US (1) US8513228B2 (pl)
EP (1) EP2408799B1 (pl)
ES (1) ES2547062T3 (pl)
HU (2) HUP0900171A2 (pl)
PL (1) PL2408799T3 (pl)
WO (1) WO2010106383A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0900487A2 (hu) * 2009-08-05 2011-03-28 Richter Gedeon Nyrt 17-acetoxi-11ß-[4-(dimetil-amino)-fenil]-21-metoxi-19-norpregna-4,9-dién-3,20-dion új kristályos polimorf módosulata és eljárás elõállítására
CN121712526A (zh) 2023-06-13 2026-03-20 辛瑟斯治疗股份有限公司 抗cd5抗体及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU710139B2 (en) * 1996-05-01 1999-09-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The 21-substituted progesterone derivatives as new antiprogestational agents
AU775831B2 (en) 1999-12-29 2004-08-19 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Process for preparing 17alpha-acetoxy-11beta-(4-N,N-(dimethylamino)phenyl)-21- methoxy-19-norpregna-4,9-diene-3,20-dione, intermediates useful in the process, and processes for preparing such intermediates
AU4584901A (en) 2000-03-17 2001-10-15 Us Gov Health & Human Serv Structural modification of 19-norprogesterone i: 17-alpha-substituted-11-beta-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
US8044223B2 (en) * 2003-04-04 2011-10-25 Bridge Organics Co. Crystalline 19-norsteroids
CA2674440A1 (en) * 2007-01-17 2008-07-24 Repros Therapeutics Inc. Methods for improved stability of steroid derivatives
HU228636B1 (en) * 2007-06-27 2013-04-29 Richter Gedeon Nyrt Industrial method for the synthesis of 17-acetoxy-11betha-4[-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process
TW201002736A (en) 2008-04-28 2010-01-16 Repros Therapeutics Inc Compositions and methods for treating progesterone-dependent conditions
HUP0900487A2 (hu) 2009-08-05 2011-03-28 Richter Gedeon Nyrt 17-acetoxi-11ß-[4-(dimetil-amino)-fenil]-21-metoxi-19-norpregna-4,9-dién-3,20-dion új kristályos polimorf módosulata és eljárás elõállítására

Also Published As

Publication number Publication date
EP2408799A1 (en) 2012-01-25
EP2408799B1 (en) 2015-07-01
US20120077791A1 (en) 2012-03-29
WO2010106383A1 (en) 2010-09-23
HU0900171D0 (en) 2009-05-28
HUE025398T2 (en) 2016-02-29
ES2547062T3 (es) 2015-10-01
US8513228B2 (en) 2013-08-20
HUP0900171A2 (hu) 2010-12-28
WO2010106383A8 (en) 2011-07-14

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