PL2573189T3 - Zwiększenie wydajności otrzymywania metioniny - Google Patents
Zwiększenie wydajności otrzymywania metioninyInfo
- Publication number
- PL2573189T3 PL2573189T3 PL12198802T PL12198802T PL2573189T3 PL 2573189 T3 PL2573189 T3 PL 2573189T3 PL 12198802 T PL12198802 T PL 12198802T PL 12198802 T PL12198802 T PL 12198802T PL 2573189 T3 PL2573189 T3 PL 2573189T3
- Authority
- PL
- Poland
- Prior art keywords
- methionine yield
- increasing methionine
- increasing
- yield
- methionine
- Prior art date
Links
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title 1
- 229930182817 methionine Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/0101—Formyltetrahydrofolate deformylase (3.5.1.10)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2007/060433 WO2009043372A1 (en) | 2007-10-02 | 2007-10-02 | Increasing methionine yield |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2573189T3 true PL2573189T3 (pl) | 2017-01-31 |
Family
ID=39521485
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08804748T PL2205754T3 (pl) | 2007-10-02 | 2008-09-25 | Zwiększanie wydajności otrzymywania metioniny |
| PL12198802T PL2573189T3 (pl) | 2007-10-02 | 2008-09-25 | Zwiększenie wydajności otrzymywania metioniny |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08804748T PL2205754T3 (pl) | 2007-10-02 | 2008-09-25 | Zwiększanie wydajności otrzymywania metioniny |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20100248311A1 (pl) |
| EP (2) | EP2205754B1 (pl) |
| JP (1) | JP5701604B2 (pl) |
| KR (2) | KR101636662B1 (pl) |
| CN (2) | CN101821401B (pl) |
| AR (1) | AR068722A1 (pl) |
| BR (1) | BRPI0818528B1 (pl) |
| DK (2) | DK2205754T3 (pl) |
| ES (2) | ES2557487T3 (pl) |
| HR (1) | HRP20160075T1 (pl) |
| HU (2) | HUE026672T2 (pl) |
| MX (1) | MX2010003609A (pl) |
| MY (2) | MY170749A (pl) |
| PL (2) | PL2205754T3 (pl) |
| RU (1) | RU2010115225A (pl) |
| WO (2) | WO2009043372A1 (pl) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4110641B2 (ja) | 1998-11-17 | 2008-07-02 | 味の素株式会社 | 発酵法によるｌ−メチオニンの製造法 |
| CN101849016A (zh) * | 2007-02-19 | 2010-09-29 | 羸创德固赛有限责任公司 | 具有甲酰基-thf-合成酶和/或甘氨酸切割活性的棒状杆菌 |
| WO2010020289A1 (en) | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity |
| WO2010020290A1 (en) * | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
| DE102009030342A1 (de) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen |
| FR2951195B1 (fr) * | 2009-10-14 | 2014-01-31 | Roquette Freres | Composition riche en methionine destinee a l'alimentation animale |
| EP2501797A4 (en) | 2009-11-18 | 2013-04-17 | Myriant Corp | TECHNIQUES OF MICROBES FOR THE EFFECTIVE MANUFACTURE OF CHEMICALS |
| WO2011073738A1 (en) | 2009-12-14 | 2011-06-23 | Metabolic Explorer | Use of inducible promoters in the production of methionine |
| JP5819316B2 (ja) | 2009-12-30 | 2015-11-24 | メタボリック エクスプローラー | コハク酸デヒドロゲナーゼを過剰発現させることによるメチオニンの増産 |
| MY172018A (en) | 2009-12-30 | 2019-11-12 | Metabolic Explorer Sa | Strains and method for the production of methionine |
| AR083468A1 (es) * | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
| BR112013016817A2 (pt) | 2010-12-30 | 2017-04-04 | Metabolic Explorer Sa | produção fermentativa de análogo hidróxi de metionina (mha) |
| WO2012090021A1 (en) | 2010-12-30 | 2012-07-05 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
| EP2479279A1 (de) * | 2011-01-20 | 2012-07-25 | Evonik Degussa GmbH | Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren |
| US9234223B2 (en) | 2011-04-01 | 2016-01-12 | Ajinomoto Co., Inc. | Method for producing L-cysteine |
| JP6020443B2 (ja) | 2011-04-01 | 2016-11-02 | 味の素株式会社 | Ｌ−システインの製造法 |
| DE102011006716A1 (de) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
| DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
| AR086790A1 (es) * | 2011-06-29 | 2014-01-22 | Metabolic Explorer Sa | Un microorganismo para la produccion de metionina con importacion de glucosa mejorada |
| FR2983870B1 (fr) | 2011-12-08 | 2015-07-17 | Roquette Freres | Composition en methionine destinee a l'alimentation animale |
| EP2628792A1 (de) | 2012-02-17 | 2013-08-21 | Evonik Industries AG | Zelle mit verringerter ppGppase-Aktivität |
| CN104302765B (zh) | 2012-04-27 | 2018-09-11 | 赢创工业化学有限公司 | 反馈抗性α-异丙基苹果酸合酶 |
| US9506093B2 (en) | 2012-06-18 | 2016-11-29 | Metabolic Explorer | Recombinant microorganism for the fermentative production of methionine |
| ES2689754T3 (es) | 2012-08-20 | 2018-11-15 | Evonik Degussa Gmbh | Procedimiento para la preparación fermentativa de L-aminoácidos utilizando cepas mejoradas de la familia Enterobacteriaceae |
| WO2014049382A2 (en) | 2012-09-26 | 2014-04-03 | Metabolic Explorer | Ethylenediamine fermentative production by a recombinant microorganism |
| DE102012024435A1 (de) | 2012-12-14 | 2014-07-10 | Forschungszentrum Jülich GmbH | Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren |
| EP2762571A1 (de) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren |
| EP2811028B1 (de) | 2013-06-03 | 2017-02-01 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Valin unter Verwendung rekombinanter Corynebakterien enthaltend das durch Propionat induzierbare ilvBN-Operon |
| MX374056B (es) | 2013-08-30 | 2020-07-27 | Evonik Operations Gmbh | Microorganismo para la produccion de metionina con actividad de metionina sintasa y eflujo de metionina mejorados. |
| EP2940039A1 (de) * | 2014-04-30 | 2015-11-04 | Evonik Degussa GmbH | Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems |
| CN103981206B (zh) * | 2014-06-06 | 2016-03-02 | 中国科学院天津工业生物技术研究所 | 一种筛选高产苏氨酸菌株的方法 |
| EP3189150B1 (en) * | 2014-09-01 | 2026-03-18 | Evonik Operations GmbH | Method and microorganism for methionine production by fermentation with improved methionine efflux |
| RU2017136561A (ru) * | 2015-03-18 | 2019-04-18 | Басф Се | Рекомбинантный микроорганизм для улучшенного получения химических продуктов тонкого органического синтеза |
| ES2811337T3 (es) | 2015-04-07 | 2021-03-11 | Metabolic Explorer Sa | Microorganismo modificado para la producción optimizada de 2,4-dihidroxibutirato con eflujo de 2,4- dihidroxibutirato aumentado |
| EP3331998B1 (en) | 2015-08-07 | 2020-06-24 | Evonik Operations GmbH | Protein thiocarboxylate-dependent l-methionine production by fermentation |
| FR3041659B1 (fr) | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| FR3041658B1 (fr) | 2015-09-30 | 2017-10-20 | Arkema France | Procede de production de l-methionine |
| US11034985B2 (en) | 2015-11-27 | 2021-06-15 | Evonik Operations Gmbh | Method for producing L-methionine |
| CA3007635A1 (en) | 2015-12-07 | 2017-06-15 | Zymergen Inc. | Promoters from corynebacterium glutamicum |
| US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
| US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
| RU2018128142A (ru) | 2016-01-08 | 2020-02-10 | Эвоник Дегусса Гмбх | Способ получения l-метионина по ферментативной технологии |
| JP2019519242A (ja) | 2016-06-30 | 2019-07-11 | ザイマージェン インコーポレイテッド | 細菌ヘモグロビンライブラリーを生成するための方法およびその使用 |
| WO2018005793A1 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a glucose permease library and uses thereof |
| EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
| CA3048992A1 (en) | 2016-12-30 | 2018-07-05 | Quidel Corporation | Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents |
| EP3354742A1 (en) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| EP3635117A2 (en) | 2017-06-07 | 2020-04-15 | Zymergen, Inc. | Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression |
| RU2020105358A (ru) | 2017-07-11 | 2021-08-11 | Адиссео Франс С.А.С. | Дрожжи, продуцирующие метионин |
| CA3076516A1 (en) | 2017-10-02 | 2019-04-11 | Quidel Corporation | Phage-based detection method for antimicrobial susceptibility testing and identification of bacterial species |
| CN109055289B (zh) * | 2018-07-27 | 2020-10-27 | 浙江工业大学 | 一种高产l-甲硫氨酸的重组大肠杆菌及其应用 |
| CN109652351B (zh) * | 2018-12-18 | 2020-08-04 | 江南大学 | 一种高产5-甲基四氢叶酸重组枯草芽孢杆菌及其应用 |
| CN113388630B (zh) * | 2020-03-11 | 2022-07-26 | 华东理工大学 | 合成l-半胱氨酸的重组大肠杆菌的构建方法及其应用 |
| JP2023534790A (ja) | 2020-07-15 | 2023-08-14 | エボニック オペレーションズ ゲーエムベーハー | オキシドレダクターゼをコードするアミノ酸配列をコードするポリヌクレオチド |
| CN112779200B (zh) * | 2021-01-12 | 2022-07-08 | 浙江工业大学 | 高产l-甲硫氨酸的基因工程菌及其构建与应用 |
| EP4384539A1 (en) | 2021-08-09 | 2024-06-19 | Evonik Operations GmbH | Polynucleotide encoding a bacterial collagen-like protein |
| WO2023016890A1 (en) | 2021-08-09 | 2023-02-16 | Evonik Operations Gmbh | Method for producing a recombinant bacterial collagen-like protein (clp) |
| WO2023016892A1 (en) | 2021-08-09 | 2023-02-16 | Evonik Operations Gmbh | Method for producing a recombinant bacterial collagen-like protein (clp) |
| CN117999103A (zh) | 2021-09-20 | 2024-05-07 | 赢创运营有限公司 | 非粘附性胶原蛋白样水凝胶 |
| CN118742338A (zh) | 2022-02-25 | 2024-10-01 | 赢创运营有限公司 | 基于胶原样蛋白的海绵 |
| CN118974074A (zh) | 2022-03-01 | 2024-11-15 | 赢创运营有限公司 | 通过重组微生物生物技术生产胶原蛋白和细菌胶原蛋白样蛋白 |
| CN121263216A (zh) | 2023-06-06 | 2026-01-02 | 赢创运营有限公司 | 由胶原样蛋白(clp)制备的水凝胶贴剂 |
| CN116590209A (zh) | 2023-06-13 | 2023-08-15 | 浙江工业大学 | 一种产d-泛酸的基因工程菌、构建方法及应用 |
| WO2025016819A1 (en) | 2023-07-20 | 2025-01-23 | Evonik Operations Gmbh | Sponge comprising a recombinant collagen-like peptide (clp) and bioactive glass |
| WO2025186007A1 (en) | 2024-03-08 | 2025-09-12 | Evonik Operations Gmbh | Collagen-like protein coated medical devices and coating method thereof |
| WO2025217267A1 (en) * | 2024-04-11 | 2025-10-16 | Natáur Inc. | Platform for bio-based production of high levels of o-phosphoserine, cysteate or taurine |
| WO2026052478A1 (en) | 2024-09-05 | 2026-03-12 | Evonik Operations Gmbh | Hybrid scaffolds comprising collagen-like protein and resorbable polymers for medical applications |
| WO2026052373A1 (en) | 2024-09-05 | 2026-03-12 | Evonik Operations Gmbh | Non-woven article comprising collagen-like protein fibers and a production process thereof |
| WO2026082572A1 (en) | 2024-10-15 | 2026-04-23 | Evonik Operations Gmbh | Chromatographic method for the purification of collagen-like protein |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0796916A1 (en) | 1996-03-22 | 1997-09-24 | Triple-A B.V. | Improvement of amino acid fermentation processes |
| JP3207746B2 (ja) | 1996-03-25 | 2001-09-10 | シャープ株式会社 | ファクシミリ装置 |
| GB9724627D0 (en) * | 1997-11-20 | 1998-01-21 | Genencor Int Bv | Gram positive microorganism formate pathway |
| JP2000157267A (ja) | 1998-11-24 | 2000-06-13 | Ajinomoto Co Inc | 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法 |
| EP2348107A3 (fr) | 2003-02-18 | 2012-07-11 | Metabolic Explorer | Procédé de préparation de microorganismes évolués permettant la création ou la modification de voies métaboliques |
| KR100488463B1 (ko) | 2003-07-24 | 2005-05-11 | 엘지전자 주식회사 | 플라즈마 디스플레이 패널의 구동장치 및 방법 |
| WO2005111202A1 (en) | 2004-05-12 | 2005-11-24 | Metabolic Explorer | Recombinant enzyme with altered feedback sensitivity |
| KR100651220B1 (ko) * | 2004-06-29 | 2006-11-29 | 씨제이 주식회사 | Ｌ-메씨오닌 생산 균주 및 상기 균주를 이용한ｌ-메씨오닌의 생산방법 |
| KR100656590B1 (ko) * | 2004-07-30 | 2006-12-11 | 한국과학기술원 | 박테리아 변이균주 및 이를 이용한 숙신산 및 아미노산의제조방법 |
| EP1846547A2 (en) * | 2005-02-07 | 2007-10-24 | Metabolic Explorer | Microorganisms comprising enzymes expressed with low gamma-elimination activity |
| MX2008000480A (es) | 2005-07-18 | 2008-03-07 | Basf Ag | Microorganismos recombinantes que producen metionina. |
| EP1931784A2 (en) * | 2005-08-18 | 2008-06-18 | Basf Se | Microorganisms with increased efficiency for methionine synthesis |
| EP1945043B1 (en) | 2005-10-31 | 2011-01-19 | Evonik Degussa GmbH | Microorganism and process for the preparation of l-methionine |
| PL1969130T3 (pl) * | 2006-01-04 | 2014-08-29 | Evonik Degussa Gmbh | Sposób wytwarzania metioniny i jej prekursorów lub sukcynylo homoseryny przy zastosowaniu mikroorganizmów |
| CN101849016A (zh) * | 2007-02-19 | 2010-09-29 | 羸创德固赛有限责任公司 | 具有甲酰基-thf-合成酶和/或甘氨酸切割活性的棒状杆菌 |
-
2007
- 2007-10-02 WO PCT/EP2007/060433 patent/WO2009043372A1/en not_active Ceased
-
2008
- 2008-09-25 KR KR1020157006914A patent/KR101636662B1/ko active Active
- 2008-09-25 HU HUE08804748A patent/HUE026672T2/en unknown
- 2008-09-25 MX MX2010003609A patent/MX2010003609A/es active IP Right Grant
- 2008-09-25 ES ES08804748.5T patent/ES2557487T3/es active Active
- 2008-09-25 KR KR1020107009579A patent/KR101586098B1/ko active Active
- 2008-09-25 JP JP2010527412A patent/JP5701604B2/ja not_active Expired - Fee Related
- 2008-09-25 HR HRP20160075TT patent/HRP20160075T1/hr unknown
- 2008-09-25 RU RU2010115225/10A patent/RU2010115225A/ru not_active Application Discontinuation
- 2008-09-25 CN CN2008801100599A patent/CN101821401B/zh active Active
- 2008-09-25 EP EP08804748.5A patent/EP2205754B1/en not_active Not-in-force
- 2008-09-25 MY MYPI2013002263A patent/MY170749A/en unknown
- 2008-09-25 PL PL08804748T patent/PL2205754T3/pl unknown
- 2008-09-25 PL PL12198802T patent/PL2573189T3/pl unknown
- 2008-09-25 MY MYPI2010001302A patent/MY180720A/en unknown
- 2008-09-25 EP EP12198802.6A patent/EP2573189B1/en not_active Not-in-force
- 2008-09-25 HU HUE12198802A patent/HUE030032T2/en unknown
- 2008-09-25 DK DK08804748.5T patent/DK2205754T3/en active
- 2008-09-25 ES ES12198802.6T patent/ES2600036T3/es active Active
- 2008-09-25 US US12/681,177 patent/US20100248311A1/en not_active Abandoned
- 2008-09-25 CN CN201210557318.0A patent/CN103087971B/zh active Active
- 2008-09-25 BR BRPI0818528-0A patent/BRPI0818528B1/pt active IP Right Grant
- 2008-09-25 WO PCT/EP2008/062859 patent/WO2009043803A2/en not_active Ceased
- 2008-09-25 DK DK12198802.6T patent/DK2573189T3/en active
- 2008-10-02 AR ARP080104317A patent/AR068722A1/es unknown
-
2016
- 2016-02-12 US US15/043,138 patent/US10858679B2/en active Active
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