PL2590629T3 - Segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów - Google Patents

Segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów

Info

Publication number
PL2590629T3
PL2590629T3 PL11741302T PL11741302T PL2590629T3 PL 2590629 T3 PL2590629 T3 PL 2590629T3 PL 11741302 T PL11741302 T PL 11741302T PL 11741302 T PL11741302 T PL 11741302T PL 2590629 T3 PL2590629 T3 PL 2590629T3
Authority
PL
Poland
Prior art keywords
polymers
release
biologically active
phase separated
active polypeptides
Prior art date
Application number
PL11741302T
Other languages
English (en)
Inventor
Rob Steendam
Theodorus Adrianus Cornelius Flipsen
Christine Hiemstra
Johan Zuidema
Original Assignee
Innocore Tech B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innocore Tech B V filed Critical Innocore Tech B V
Publication of PL2590629T3 publication Critical patent/PL2590629T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • A61K38/385Serum albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/026Specifications of the specimen
    • G01N2203/0262Shape of the specimen
    • G01N2203/0278Thin specimens
    • G01N2203/0282Two dimensional, e.g. tapes, webs, sheets, strips, disks or membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
PL11741302T 2010-07-09 2011-07-08 Segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów PL2590629T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36271010P 2010-07-09 2010-07-09
PCT/NL2011/050502 WO2012005594A2 (en) 2010-07-09 2011-07-08 Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides
EP11741302.1A EP2590629B1 (en) 2010-07-09 2011-07-08 Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides

Publications (1)

Publication Number Publication Date
PL2590629T3 true PL2590629T3 (pl) 2015-04-30

Family

ID=44629868

Family Applications (2)

Application Number Title Priority Date Filing Date
PL14195906T PL2859887T3 (pl) 2010-07-09 2011-07-08 Biodegradowalne segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów
PL11741302T PL2590629T3 (pl) 2010-07-09 2011-07-08 Segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL14195906T PL2859887T3 (pl) 2010-07-09 2011-07-08 Biodegradowalne segmentowane kopolimery wieloblokowe z rozdziałem faz oraz uwalnianie biologicznie czynnych polipeptydów

Country Status (8)

Country Link
US (1) US9364442B2 (pl)
EP (2) EP2859887B1 (pl)
CA (1) CA2804601C (pl)
DK (2) DK2859887T3 (pl)
ES (2) ES2527193T3 (pl)
HU (1) HUE033386T2 (pl)
PL (2) PL2859887T3 (pl)
WO (1) WO2012005594A2 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012005594A2 (en) 2010-07-09 2012-01-12 Innocore Technologies B.V. Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides
FI128487B (en) * 2013-05-06 2020-06-15 Teknologian Tutkimuskeskus Vtt Oy Glycolic acid polymers and process for their preparation
GB201405874D0 (en) * 2014-04-01 2014-05-14 Aga Nanotech Ltd A therapeutic agent for use in the treatment of infections
JP6949820B2 (ja) 2015-08-03 2021-10-13 トルマー インターナショナル リミテッド 薬物の持続投与のための液体ポリマー送達システム
US10353503B2 (en) * 2015-10-29 2019-07-16 Texas Instruments Incorporated Integrated force sensing element
HUE058207T2 (hu) 2017-01-31 2022-07-28 Veru Inc Készítmények és módszerek gonadotropin felszabadító hormon (GNRH) antagonisták elnyújtott idejû felszabadítására
EP3658117A1 (en) * 2017-07-25 2020-06-03 Pk Med Sas Process for preparing a drug delivery composition
EP3628698B1 (en) 2018-09-26 2024-11-20 Covidien LP Biodegradable triblock copolymers and implantable medical devices made therefrom
JP2022506554A (ja) * 2018-10-29 2022-01-17 プージン ケミカル インダストリー カンパニー リミテッド 耐高温性、耐老化性ポリグリコライドコポリマーおよびその組成
CA3116438C (en) * 2018-10-29 2023-08-22 Pujing Chemical Industry Co., Ltd Polyglycolide copolymer and preparation thereof
WO2021062079A1 (en) 2019-09-25 2021-04-01 Carbon, Inc. Particle coating methods for additively manufactured products
HUE069400T2 (hu) * 2019-09-30 2025-03-28 Tolmar International Ltd Folyékony polimer készítmények és rendszerek peptidek mint hatóanyagok nyújtott leadására
JP7737981B2 (ja) 2019-10-01 2025-09-11 イノコア テクノロジーズ ホールディング ビー.ブイ. 生分解性の相分離した熱可塑性マルチブロックコポリマー
US20220331258A1 (en) 2019-10-01 2022-10-20 Allergan Sales, Llc Poly-Dioxanone Multi-Block Copolymer for Ocular Protein Delivery
JP7737983B2 (ja) * 2019-11-01 2025-09-11 インノコア テクノロジーズ ビー.ブイ. 抗体又は巨大タンパク質の延長された放出の為の剤形物
CN114621450B (zh) * 2021-04-07 2023-05-05 江苏睿安应用生物技术股份有限公司 一种扩链改性生物降解聚酯的方法及其应用
US20250206872A1 (en) 2022-03-17 2025-06-26 InnoCore Technologies Holding B.V. Biodegradable thermoplastic poly(ortho ester) based multiblock copolymers
WO2026015019A1 (en) 2024-07-08 2026-01-15 InnoCore Technologies Holding B.V. Biodegradable thermoplastic polyoxazoline based copolymers

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Publication number Priority date Publication date Assignee Title
US4429080A (en) 1982-07-01 1984-01-31 American Cyanamid Company Synthetic copolymer surgical articles and method of manufacturing the same
US4643734A (en) 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
US5066772A (en) 1987-12-17 1991-11-19 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5133739A (en) 1990-02-06 1992-07-28 Ethicon, Inc. Segmented copolymers of ε-caprolactone and glycolide
US5236444A (en) 1992-10-27 1993-08-17 United States Surgical Corporation Absorbable polymers and surgical articles made therefrom
US5403347A (en) 1993-05-27 1995-04-04 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5980948A (en) 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US6255408B1 (en) 1998-11-06 2001-07-03 Poly-Med, Inc. Copolyesters with minimized hydrolytic instability and crystalline absorbable copolymers thereof
EP1382628A1 (en) 2002-07-16 2004-01-21 Polyganics B.V. Biodegradable phase separated segmented/block co-polyesters
EP1555278A1 (en) 2004-01-15 2005-07-20 Innocore Technologies B.V. Biodegradable multi-block co-polymers
NL1026261C2 (nl) 2004-05-25 2005-11-28 Nanomi B V Sproei inrichting met een nozzleplaat voorzien van structuren ter bevordering van self-breakup, een nozzleplaat, alsmede werkwijzen ter vervaardiging en toepassing van een dergelijke nozzleplaat.
JP5203695B2 (ja) 2007-12-28 2013-06-05 ヤマハ発動機株式会社 遠心クラッチ、エンジンユニット及び鞍乗型車両
WO2012005594A2 (en) 2010-07-09 2012-01-12 Innocore Technologies B.V. Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides

Also Published As

Publication number Publication date
US20130209568A1 (en) 2013-08-15
HUE033386T2 (en) 2017-11-28
PL2859887T3 (pl) 2017-10-31
CA2804601C (en) 2020-05-19
ES2527193T3 (es) 2015-01-21
EP2859887A1 (en) 2015-04-15
CA2804601A1 (en) 2012-01-12
WO2012005594A3 (en) 2012-07-05
ES2628931T3 (es) 2017-08-04
US9364442B2 (en) 2016-06-14
WO2012005594A2 (en) 2012-01-12
EP2859887B1 (en) 2017-03-22
EP2590629A2 (en) 2013-05-15
EP2590629B1 (en) 2014-12-03
DK2859887T3 (en) 2017-06-26
DK2590629T3 (en) 2015-01-12

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