PL2598531T3 - Sposoby i kompozycje do terapii nowotworu wątroby - Google Patents

Sposoby i kompozycje do terapii nowotworu wątroby

Info

Publication number
PL2598531T3
PL2598531T3 PL11738200T PL11738200T PL2598531T3 PL 2598531 T3 PL2598531 T3 PL 2598531T3 PL 11738200 T PL11738200 T PL 11738200T PL 11738200 T PL11738200 T PL 11738200T PL 2598531 T3 PL2598531 T3 PL 2598531T3
Authority
PL
Poland
Prior art keywords
compositions
treatment
methods
liver cancer
liver
Prior art date
Application number
PL11738200T
Other languages
English (en)
Inventor
Leila Houhou
Anne-Sophie DUMÉ
Dominique Joubert
Frederic Hollande
Original Assignee
Progastrine Et Cancers S.À R.L.
INSERM (Institut National de la Santé et de la Recherche Médicale)
Centre National De La Recherche Scientifique (C.N.R.S.)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progastrine Et Cancers S.À R.L., INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National De La Recherche Scientifique (C.N.R.S.) filed Critical Progastrine Et Cancers S.À R.L.
Publication of PL2598531T3 publication Critical patent/PL2598531T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL11738200T 2010-07-26 2011-07-22 Sposoby i kompozycje do terapii nowotworu wątroby PL2598531T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36785110P 2010-07-26 2010-07-26
US201161476204P 2011-04-15 2011-04-15
EP11738200.2A EP2598531B1 (en) 2010-07-26 2011-07-22 Methods and compositions for liver cancer therapy
PCT/EP2011/062686 WO2012013609A1 (en) 2010-07-26 2011-07-22 Methods and compositions for liver cancer therapy

Publications (1)

Publication Number Publication Date
PL2598531T3 true PL2598531T3 (pl) 2021-08-30

Family

ID=45493809

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11738200T PL2598531T3 (pl) 2010-07-26 2011-07-22 Sposoby i kompozycje do terapii nowotworu wątroby

Country Status (16)

Country Link
US (1) US10533050B2 (pl)
EP (1) EP2598531B1 (pl)
JP (1) JP5726305B2 (pl)
KR (1) KR101576174B1 (pl)
CN (1) CN103261224B (pl)
AR (1) AR082340A1 (pl)
AU (1) AU2011284908B2 (pl)
BR (1) BR112013002012A2 (pl)
CA (1) CA2806157C (pl)
EA (2) EA028515B1 (pl)
ES (1) ES2871092T3 (pl)
NZ (1) NZ606195A (pl)
PL (1) PL2598531T3 (pl)
SG (2) SG187544A1 (pl)
WO (1) WO2012013609A1 (pl)
ZA (1) ZA201300567B (pl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011001445A (es) 2008-08-05 2011-04-05 Toray Industries Metodo para detectar cancer.
BRPI0911926A2 (pt) 2008-08-05 2020-08-18 Toray Industries, Inc composições farmacêuticas, anticorpos e usos de um anticorpo ou um fragmento do mesmo.
EP2488551B1 (en) * 2009-10-16 2018-07-25 Progastrine et Cancers S.à r.l. Monoclonal antibodies to progastrin and their uses
US8900817B2 (en) 2010-01-08 2014-12-02 Les Laboratories Servier Progastrin and liver pathologies
RU2603742C2 (ru) 2010-02-04 2016-11-27 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения и/или профилактики рака
PT2740489T (pt) 2011-08-04 2017-01-10 Toray Industries Composição farmacêutica para o tratamento e/ou a prevenção do cancro pancreático
ES2629061T3 (es) 2011-08-04 2017-08-07 Toray Industries, Inc. Método para la detección de cáncer pancreático
PT2740796T (pt) 2011-08-04 2017-07-26 Toray Industries Composição farmacêutica para o tratamento e/ou profilaxia de cancro
US9260513B2 (en) 2012-02-21 2016-02-16 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
WO2013125654A1 (ja) 2012-02-21 2013-08-29 東レ株式会社 癌の治療及び／又は予防用医薬組成物
BR112014021103A2 (pt) 2012-02-21 2019-10-15 Toray Industries, Inc Anticorpo, composição farmacêutica, droga de combinação, dna, método de tratamento e uso de anticorpo
ES2739612T3 (es) 2012-02-21 2020-02-03 Toray Industries Composición farmacéutica para el tratamiento de cáncer
WO2013147176A1 (ja) 2012-03-30 2013-10-03 東レ株式会社 胆嚢癌の治療及び／又は予防用医薬組成物
JP6107654B2 (ja) 2012-03-30 2017-04-05 東レ株式会社 肝臓癌の治療及び／又は予防用医薬組成物
PL2876447T3 (pl) 2012-07-19 2020-05-18 Toray Industries, Inc. Sposób wykrywania nowotworu
MX357292B (es) 2012-07-19 2018-07-04 Toray Industries Método para detectar cáncer.
AU2014303375B2 (en) 2013-08-09 2019-07-04 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
EA033526B1 (ru) * 2014-09-10 2019-10-31 Double Bond Pharmaceuticals Ab Адресная доставка гидрофильных лекарственных средств
EP3023884A1 (en) * 2014-11-21 2016-05-25 Thomson Licensing Method and apparatus for generating fingerprint of an audio signal
KR102197478B1 (ko) 2015-12-31 2021-01-04 프로가스트린 에 캔서스 에스.에이 알.엘. 식도암을 검출 및 치료하기 위한 조성물 및 방법
ES3015244T3 (en) 2015-12-31 2025-04-30 Ecs Progastrin Sa Compositions and methods for detecting and treating ovarian cancer
KR102477179B1 (ko) 2015-12-31 2022-12-13 프로가스트린 에 캔서스 에스.에이 알.엘. 위암의 검출 및 치료를 위한 조성물 및 방법
MA43550A (fr) 2015-12-31 2018-11-07 Syncerus S A R L Compositions et procédés d'évaluation du risque d'apparition d'un cancer
KR102317805B1 (ko) 2017-03-30 2021-10-27 이씨에스-프로가스트린 에스에이 전립선암을 검출하기 위한 조성물 및 방법
SG11201908996YA (en) * 2017-03-30 2019-10-30 Ecs Progastrin Sa Compositions and methods for detecting lung cancer
WO2019110662A1 (en) * 2017-12-05 2019-06-13 Progastrine Et Cancers S.À R.L. Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
EP3759492A1 (en) 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
AU2020358101A1 (en) * 2019-10-02 2022-04-28 Alamab Therapeutics, Inc. Anto-connexin antibody formulations
TW202521577A (zh) * 2023-08-04 2025-06-01 大陸商信達生物製藥（蘇州）有限公司 抗ｏｘ４０ｌ抗體以及其用途

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4510245A (en) 1982-11-18 1985-04-09 Chiron Corporation Adenovirus promoter system
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
CA2328501A1 (en) * 1998-05-15 1999-11-25 Aphton Corporation Prevention and treatment of hypergastrinemia
US20030021786A1 (en) * 2001-07-09 2003-01-30 Gevas Philip C. Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
AU2004247069A1 (en) * 2003-06-02 2004-12-23 Alexion Pharmaceuticals, Inc. Cell surface protein associated with human chronic lymphocytic leukemia
DK1794586T3 (da) * 2004-09-22 2013-05-13 Cancer Advances Inc Monoklonale antistoffer til progastrin
US20100209426A1 (en) * 2006-05-22 2010-08-19 Inserm (Institut National De La Sante Et De La Rec Herche Medicale) Inhibitors of progastrin-induced repression of icat for treating and/or preventing colorectal cancer, adenomatous polyposis or metastasis displaying progastrin-secreting cells and cells in which the beta-catenin/tcf-mediated transcriptional pathway is constitutively active
US7854932B2 (en) * 2006-12-19 2010-12-21 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
EP2488551B1 (en) * 2009-10-16 2018-07-25 Progastrine et Cancers S.à r.l. Monoclonal antibodies to progastrin and their uses
US8900817B2 (en) * 2010-01-08 2014-12-02 Les Laboratories Servier Progastrin and liver pathologies
US9217032B2 (en) * 2010-01-08 2015-12-22 Les Laboratoires Servier Methods for treating colorectal cancer
US9487582B2 (en) * 2010-01-08 2016-11-08 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for treating pancreatic cancer
JP5829672B2 (ja) * 2010-03-24 2015-12-09 レ ラボラトワール セルヴィエ 結腸直腸及び胃腸癌の予防

Also Published As

Publication number Publication date
EA201300171A1 (ru) 2013-07-30
EP2598531B1 (en) 2020-12-30
JP5726305B2 (ja) 2015-05-27
US20120020961A1 (en) 2012-01-26
WO2012013609A1 (en) 2012-02-02
US10533050B2 (en) 2020-01-14
NZ606195A (en) 2015-02-27
CA2806157A1 (en) 2012-02-02
ZA201300567B (en) 2014-03-26
AU2011284908A1 (en) 2013-02-07
CA2806157C (en) 2016-11-22
SG187544A1 (en) 2013-03-28
JP2013533277A (ja) 2013-08-22
CN103261224B (zh) 2015-10-07
AU2011284908B2 (en) 2015-05-21
EA201790882A1 (ru) 2017-08-31
BR112013002012A2 (pt) 2019-08-27
KR101576174B1 (ko) 2015-12-09
AR082340A1 (es) 2012-11-28
EA028515B1 (ru) 2017-11-30
CN103261224A (zh) 2013-08-21
KR20130083438A (ko) 2013-07-22
SG10201703556YA (en) 2017-06-29
EP2598531A1 (en) 2013-06-05
ES2871092T3 (es) 2021-10-28

Similar Documents

Publication Publication Date Title
PL2598531T3 (pl) Sposoby i kompozycje do terapii nowotworu wątroby
HUS2100055I1 (hu) IBAT-inhibitorok májbetegségek kezelésére
PL3443957T3 (pl) Związki i kompozycje stosowane w leczeniu nowotworów
IL225471A0 (en) Compositions and methods for the prevention and treatment of cancer
PL2552438T3 (pl) Sposoby leczenia raka wątrobowokomórkowego
EP2877159B8 (en) Efflux inhibitor compositions and methods of treatment using the same
PL3023788T3 (pl) Kompozycje neoantygenów specyficznych wobec nowotworu do zastosowania w leczeniu nowotworów
BR112014001440A2 (pt) novas composições e métodos para o tratamento de câncer de próstata
PL2558095T3 (pl) Związek organiczny, przeznaczony do stosowania w leczeniu raka wątroby
PL3199024T3 (pl) Zastosowanie kompozycji cyklodekstryny i stosowne sposoby
IL225262A0 (en) Methods and compositions for treating lung cancer
SG10201500124VA (en) Methods and Compositions for Treating Cancer
ITTO20110641A1 (it) Composizioni farmaceutiche e metodi di trattamento
IL238177A0 (en) Methods and preparations for the treatment of cancer
PL2830654T3 (pl) Sposoby i kompozycje do leczenia zapalenia
IL220386B (en) Compositions for the liquidation of tumors and uses thereof
EP2526118A4 (en) COMPOSITIONS AND METHOD FOR THE TREATMENT OF EGG CANCER
IL226246A0 (en) Methods of treating cancer
PT2605764E (pt) Composições para o tratamento de cancro
PL2718434T3 (pl) Kompozycje i sposoby leczenia choroby trzewnej
IL214349A0 (en) Compositions and methods for the treatment of cancer
IL231907B (en) Compounds and compositions for treatment of transthyretin-associated amyloidosis
BR112013028890A2 (pt) composições e métodos para o tratamento de câncer
WO2012003421A9 (en) Combinational compositions and methods for treatment of cancer
EP2547368A4 (en) METHOD AND COMPOSITIONS FOR CANCER TREATMENT