PL2609120T3 - Ulepszony sposób wytwarzania sugammadeksu - Google Patents

Ulepszony sposób wytwarzania sugammadeksu

Info

Publication number: PL2609120T3
Authority: PL; Poland
Prior art keywords: sugammadex; preparation; improved process; improved
Prior art date: 2010-08-25

Application number

PL11819525T

Other languages

English (en)

Inventor

Ravi Ponnaiah

Ravi Kanth Sribhashyam

Valsan Nandkumar Mecherili

Naresh Dongari

Prasad Chlnv

Guruswamy Batthini

Original Assignee

Davuluri Ramamohan Rao

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-08-25

Filing date

2011-08-23

Publication date

2016-03-31

2011-08-23 Application filed by Davuluri Ramamohan Rao filed Critical Davuluri Ramamohan Rao

2016-03-31 Publication of PL2609120T3 publication Critical patent/PL2609120T3/pl

Links

229920002370 Sugammadex Polymers 0.000 title 1
WHRODDIHRRDWEW-VTHZAVIASA-N sugammadex Chemical compound O([C@@H]([C@@H]([C@H]1O)O)O[C@H]2[C@H](O)[C@H]([C@@H](O[C@@H]3[C@@H](CSCCC(O)=O)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]3[C@@H](CSCCC(O)=O)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]3[C@@H](CSCCC(O)=O)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]3[C@@H](CSCCC(O)=O)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]3[C@@H](CSCCC(O)=O)O[C@@H]([C@@H]([C@H]3O)O)O3)O[C@@H]2CSCCC(O)=O)O)[C@H](CSCCC(O)=O)[C@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H]3[C@@H](CSCCC(O)=O)O1 WHRODDIHRRDWEW-VTHZAVIASA-N 0.000 title 1
229960002257 sugammadex Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL11819525T 2010-08-25 2011-08-23 Ulepszony sposób wytwarzania sugammadeksu PL2609120T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IN2459CH2010		2010-08-25
EP11819525.4A EP2609120B1 (en)	2010-08-25	2011-08-23	Improved process for preparation of sugammadex
PCT/IN2011/000562 WO2012025937A1 (en)	2010-08-25	2011-08-23	Improved process for preparation of sugammadex

Publications (1)

Publication Number	Publication Date
PL2609120T3 true PL2609120T3 (pl)	2016-03-31

Family

ID=45722983

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL11819525T PL2609120T3 (pl)	2010-08-25	2011-08-23	Ulepszony sposób wytwarzania sugammadeksu

Country Status (5)

Country	Link
US (1)	US9120876B2 (pl)
EP (1)	EP2609120B1 (pl)
ES (1)	ES2551585T3 (pl)
PL (1)	PL2609120T3 (pl)
WO (1)	WO2012025937A1 (pl)

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US9879096B2 (en)	2013-02-14	2018-01-30	Neuland Laboratories Limited	Process for preparation of sugammadex sodium
CN105273095A (zh) *	2014-05-28	2016-01-27	四川海思科制药有限公司	一种舒更葡糖钠及其中间体的制备方法
LU92569B1 (en)	2014-05-28	2016-04-11	Univ Saarland	Novel water soluble 6-thioalkyl-cyclodextrins and uses thereof
CN104844732B (zh) *	2015-03-27	2017-05-03	山东滨州智源生物科技有限公司	一种舒更葡糖钠的制备方法
JP6946275B2 (ja) *	2015-05-29	2021-10-06	ラクシュミ・プラサド・アラパルティＬａｋｓｈｍｉＰｒａｓａｄＡＬＡＰＡＲＴＨＩ	スガマデクスおよびその中間体の製造方法
AU2016359420B2 (en) *	2015-11-25	2020-10-01	Fresenius Kabi Ipsum S.R.L.	An improved process for the preparation of sugammadex and its intermediates
KR102251683B1 (ko) *	2015-11-25	2021-05-13	프레제니우스 카비 입섬 에스. 알. 엘.	퍼-클로로-감마-시클로덱스트린의 결정형
US10577433B2 (en)	2016-03-22	2020-03-03	Fresenius Kabi Ipsum S.R.L.	Process for the preparation of sugammadex
HRP20220705T1 (hr)	2016-06-23	2022-07-22	Synthon B.V.	Postupak dobivanja sugamadeksa
JP6692941B2 (ja)	2016-06-29	2020-05-27	北京叡創康泰医薬研究院有限公司ＢｅｉｊｉｎｇＣｒｅａｔｒｏｎＩｎｓｔｉｔｕｔｅｏｆＰｈａｒｍａｃｅｕｔｉｃａｌＲｅｓｅａｒｃｈＣｏ．，Ｌｔｄ．	スガマデックスの製造及び純化方法
US10526422B2 (en)	2016-06-29	2020-01-07	Beijing Creatron Institute Of Pharmaceutical Research Co., Ltd.	Process for preparation and purification of Sugammades sodium
CN107778383B (zh) *	2016-08-24	2020-03-10	王炳永	一种舒更葡糖钠的精制方法
US10385142B2 (en)	2017-01-23	2019-08-20	Scinopharm Taiwan, Ltd.	Method for preparing sugammadex sodium
CN108929390A (zh) *	2017-05-23	2018-12-04	合肥博思科创医药科技有限公司	一种微波反应合成舒更葡糖钠的方法
CN109021148B (zh) *	2017-06-08	2020-11-10	天津科伦药物研究有限公司	一种制备舒更葡糖钠的方法
US10442871B2 (en)	2017-06-22	2019-10-15	Lawrence Livermore National Security, Llc	Modified cyclodextrins for the selective sequestration of fentanyl related compounds and uses thereof
ES2761899T3 (es)	2017-06-30	2020-05-21	Synthon Bv	Proceso para preparar Sugammadex
US10233263B1 (en) *	2017-08-23	2019-03-19	Formosa Laboratories, Inc.	Method for preparation of sugammadex sodium
TWI703163B (zh) *	2017-08-23	2020-09-01	台耀化學股份有限公司	舒更葡糖鈉之製備方法及其晶型
CN107686530B (zh) *	2017-10-16	2019-09-13	河北坤安药业有限公司	一种舒更葡糖钠的合成方法
CN108047354B (zh) *	2017-11-07	2020-05-26	山东达冠医药科技有限公司	一种高纯度舒更葡糖钠及其中间体的制备及纯化方法
CN111615522B (zh)	2017-11-27	2023-04-18	摩迪康公司	用于合成环糊精衍生物的方法
US11225565B2 (en)	2018-04-06	2022-01-18	Synthon B.V.	Purification of sugammadex
KR102054228B1 (ko) *	2018-05-28	2019-12-10	연성정밀화학(주)	슈가마덱스 나트륨염의 제조방법
AU2019281969B2 (en)	2018-06-07	2024-03-07	Merck Sharp & Dohme Llc	Processes for the preparation of sugammadex
WO2020013759A1 (en) *	2018-07-12	2020-01-16	Scinopharm Taiwan Ltd.	Method for preparing sugammadex sodium
US11845811B2 (en)	2018-09-20	2023-12-19	Natco Pharma Limited	Process for the preparation of Sugammadex sodium and its novel polymorphic form
US20220017650A1 (en) *	2018-12-11	2022-01-20	Biophore India Pharmaceuticals Pvt. Ltd.	Novel process for the purification of sugammadex sodium
CN109824800A (zh) *	2018-12-29	2019-05-31	鼎元(天津)生物医药科技有限公司	一种选择性肌松拮抗药舒更葡萄糖钠的制备方法
CN109593143B (zh) *	2018-12-29	2021-02-09	博瑞生物医药（苏州）股份有限公司	一种舒更葡糖钠制备中间体的纯化方法
CN109438591B (zh) *	2018-12-29	2021-02-09	博瑞生物医药（苏州）股份有限公司	舒更葡糖钠的制备工艺
CN109517094A (zh) *	2019-01-18	2019-03-26	苏州纳微科技股份有限公司	一种舒更葡糖的分离纯化方法
WO2020201930A1 (en)	2019-03-29	2020-10-08	Hospira, Inc.	An improved process for preparation of sugammadex acid and sugammadex sodium
EP4110832A1 (en)	2020-02-28	2023-01-04	Medichem, S.A.	Method for drying sugammadex
US11097023B1 (en)	2020-07-02	2021-08-24	Par Pharmaceutical, Inc.	Pre-filled syringe containing sugammadex

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US4980463A (en) *	1989-07-18	1990-12-25	Noramco, Inc.	Sucrose-6-ester chlorination
TWI242015B (en)	1999-11-29	2005-10-21	Akzo Nobel Nv	6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
MX2007013689A (es) *	2005-05-04	2009-02-17	Pharmed Medicare Pvt Ltd	Generacion de oxicloruro de fosforo como subproducto de pentacloruro de fosforo y dmf y su uso en una reaccion de cloracion al convertirse en reactivo vilsmeier-haack.
US20090069412A1 (en) *	2007-09-09	2009-03-12	Protia, Llc	Deuterium-enriched sugammadex

2011
- 2011-08-23 PL PL11819525T patent/PL2609120T3/pl unknown
- 2011-08-23 US US13/818,658 patent/US9120876B2/en not_active Expired - Fee Related
- 2011-08-23 EP EP11819525.4A patent/EP2609120B1/en not_active Not-in-force
- 2011-08-23 ES ES11819525.4T patent/ES2551585T3/es active Active
- 2011-08-23 WO PCT/IN2011/000562 patent/WO2012025937A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP2609120A4 (en)	2013-10-02
ES2551585T3 (es)	2015-11-20
WO2012025937A1 (en)	2012-03-01
EP2609120A1 (en)	2013-07-03
US20140221641A1 (en)	2014-08-07
EP2609120B1 (en)	2015-07-29
US9120876B2 (en)	2015-09-01

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