PL2646010T3 - Kombinacja kwas foliowy-ramipryl: kompozycje okulistyczne chroniące komórki, neuroprotekcyjne i retinoprotekcyjne - Google Patents

Kombinacja kwas foliowy-ramipryl: kompozycje okulistyczne chroniące komórki, neuroprotekcyjne i retinoprotekcyjne

Info

Publication number: PL2646010T3
Authority: PL; Poland
Prior art keywords: cellprotective; ophtalmologic; retinoprotective; neuroprotective; compositions
Prior art date: 2010-12-03

Application number

PL11724029T

Other languages

English (en)

Inventor

Raouf Rekik

Original Assignee

Raouf Rekik

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-12-03

Filing date

2011-05-06

Publication date

2020-06-01

2011-05-06 Application filed by Raouf Rekik filed Critical Raouf Rekik

2020-06-01 Publication of PL2646010T3 publication Critical patent/PL2646010T3/pl

Links

OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 title 2
OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 title 1
229960000304 folic acid Drugs 0.000 title 1
235000019152 folic acid Nutrition 0.000 title 1
239000011724 folic acid Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1
230000000324 neuroprotective effect Effects 0.000 title 1
229960003401 ramipril Drugs 0.000 title 1
230000003289 retinoprotective effect Effects 0.000 title 1

Classifications

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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Inorganic Chemistry (AREA)
Diabetes (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Hematology (AREA)
Obesity (AREA)
Tropical Medicine & Parasitology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
AIDS & HIV (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)

PL11724029T 2010-12-03 2011-05-06 Kombinacja kwas foliowy-ramipryl: kompozycje okulistyczne chroniące komórki, neuroprotekcyjne i retinoprotekcyjne PL2646010T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
TNP2010000566A TN2010000566A1 (en)	2010-12-03	2010-12-03	Folic acid - ramipril combination : cell protective neuroprotective and retinoprotective ophtalmologic drugs
EP11724029.1A EP2646010B1 (en)	2010-12-03	2011-05-06	Folic acid - ramipril combination: cellprotective, neuroprotective and retinoprotective ophtalmologic compositions
PCT/IB2011/000960 WO2012073077A1 (en)	2010-12-03	2011-05-06	Folic acid - ramipril combination: cellprotective, neuroprotective and retinoprotective ophtalmologic compositions

Publications (1)

Publication Number	Publication Date
PL2646010T3 true PL2646010T3 (pl)	2020-06-01

Family

ID=54696113

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL11724029T PL2646010T3 (pl)	2010-12-03	2011-05-06	Kombinacja kwas foliowy-ramipryl: kompozycje okulistyczne chroniące komórki, neuroprotekcyjne i retinoprotekcyjne

Country Status (12)

Country	Link
US (2)	US20130317036A1 (pl)
EP (1)	EP2646010B1 (pl)
JP (1)	JP5897592B2 (pl)
CN (1)	CN103338758B (pl)
AU (1)	AU2011334617B2 (pl)
CA (1)	CA2819628C (pl)
ES (1)	ES2770410T3 (pl)
PL (1)	PL2646010T3 (pl)
RU (1)	RU2602738C2 (pl)
TN (1)	TN2010000566A1 (pl)
WO (1)	WO2012073077A1 (pl)
ZA (1)	ZA201304026B (pl)

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PT3445351T (pt) *	2016-04-19	2024-11-14	Intrabio Ltd	Acetil-leucina ou um sal farmaceuticamente aceitável seu derivado para melhoria da mobilidade
TN2016000259A1 (en) *	2016-06-27	2017-10-06	Rekik Raouf	Salbutamol (albuterol) eye protective medicament.
PT3482754T (pt)	2016-08-11	2021-02-03	Intrabio Ltd	Composições farmacêuticas e utilizações contra os distúrbios de armazenamento lisossómico
TN2019000033A1 (fr) *	2016-08-11	2020-07-15	Intrabio Ltd	Agents thérapeutiques pour maladies neurodégénératives
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EP3616700A1 (en) *	2018-08-29	2020-03-04	Aprofol AG	Folate preparations for use in the treatment of eye diseases
RU2717343C1 (ru) *	2019-03-01	2020-03-23	Евгений Владимирович Плотников	Средство, обладающее цитопротекторным действием
MD3989962T2 (ro)	2019-06-28	2025-12-31	Intrabio Ltd Gb	Terapie combinată cu acetil-leucină și miglustat pentru tratamentul unei boli de depozitare lizozomală
WO2021144720A1 (en)	2020-01-13	2021-07-22	Intrabio Ltd	Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers
CN114917345A (zh) *	2021-04-07	2022-08-19	北京蛋白质组研究中心	靶向soat1蛋白的化合物在制备预防和/或治疗肝癌药物中的应用
CN117561065A (zh) *	2021-06-24	2024-02-13	连云港金康和信药业有限公司	叶酸类衍生物在制备治疗隐形眼镜不适及干眼症药物的应用

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2010
- 2010-12-03 TN TNP2010000566A patent/TN2010000566A1/fr unknown
2011
- 2011-05-06 JP JP2013541436A patent/JP5897592B2/ja not_active Expired - Fee Related
- 2011-05-06 ES ES11724029T patent/ES2770410T3/es active Active
- 2011-05-06 EP EP11724029.1A patent/EP2646010B1/en active Active
- 2011-05-06 AU AU2011334617A patent/AU2011334617B2/en not_active Ceased
- 2011-05-06 US US13/991,286 patent/US20130317036A1/en not_active Abandoned
- 2011-05-06 WO PCT/IB2011/000960 patent/WO2012073077A1/en not_active Ceased
- 2011-05-06 CA CA2819628A patent/CA2819628C/en active Active
- 2011-05-06 PL PL11724029T patent/PL2646010T3/pl unknown
- 2011-05-06 RU RU2013125146/15A patent/RU2602738C2/ru active
- 2011-05-06 CN CN201180066768.3A patent/CN103338758B/zh not_active Expired - Fee Related
2013
- 2013-05-31 ZA ZA2013/04026A patent/ZA201304026B/en unknown
2015
- 2015-01-16 US US14/599,223 patent/US20150133455A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2646010A1 (en)	2013-10-09
WO2012073077A1 (en)	2012-06-07
AU2011334617B2 (en)	2017-01-12
US20130317036A1 (en)	2013-11-28
JP2013544275A (ja)	2013-12-12
AU2011334617A1 (en)	2013-06-20
TN2010000566A1 (en)	2012-05-24
CA2819628C (en)	2019-12-03
ZA201304026B (en)	2014-02-26
CN103338758B (zh)	2017-12-12
ES2770410T3 (es)	2020-07-01
RU2602738C2 (ru)	2016-11-20
US20150133455A1 (en)	2015-05-14
EP2646010B1 (en)	2019-11-13
AU2011334617A2 (en)	2013-08-01
CA2819628A1 (en)	2012-06-07
JP5897592B2 (ja)	2016-03-30
CN103338758A (zh)	2013-10-02
RU2013125146A (ru)	2015-01-10

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