PL2687518T3 - Nasycony związek heterocykliczny zawierający azot - Google Patents

Nasycony związek heterocykliczny zawierający azot

Info

Publication number
PL2687518T3
PL2687518T3 PL12757539T PL12757539T PL2687518T3 PL 2687518 T3 PL2687518 T3 PL 2687518T3 PL 12757539 T PL12757539 T PL 12757539T PL 12757539 T PL12757539 T PL 12757539T PL 2687518 T3 PL2687518 T3 PL 2687518T3
Authority
PL
Poland
Prior art keywords
heterocyclic compound
containing heterocyclic
nitrogen containing
saturated nitrogen
saturated
Prior art date
Application number
PL12757539T
Other languages
English (en)
Inventor
Toru Iijima
Hiroshi Sugama
Takayuki Kawaguchi
Jingkang Shen
Guangxin Xia
Jianshu Xie
Miki Hirai
Original Assignee
Mitsubishi Tanabe Pharma Corporation
Shanghai Pharmaceuticals Holding Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corporation, Shanghai Pharmaceuticals Holding Co., Ltd. filed Critical Mitsubishi Tanabe Pharma Corporation
Publication of PL2687518T3 publication Critical patent/PL2687518T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL12757539T 2011-03-16 2012-03-15 Nasycony związek heterocykliczny zawierający azot PL2687518T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011058338 2011-03-16
EP12757539.7A EP2687518B1 (en) 2011-03-16 2012-03-15 Nitrogen-containing saturated heterocyclic compound
PCT/JP2012/056750 WO2012124775A1 (ja) 2011-03-16 2012-03-15 含窒素飽和複素環化合物

Publications (1)

Publication Number Publication Date
PL2687518T3 true PL2687518T3 (pl) 2018-04-30

Family

ID=46830839

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12757539T PL2687518T3 (pl) 2011-03-16 2012-03-15 Nasycony związek heterocykliczny zawierający azot

Country Status (18)

Country Link
US (2) US9278944B2 (pl)
EP (1) EP2687518B1 (pl)
JP (1) JP5760078B2 (pl)
KR (1) KR101651722B1 (pl)
CN (1) CN103562191B (pl)
AU (1) AU2012229859C1 (pl)
BR (1) BR112013023480B1 (pl)
CA (1) CA2828378C (pl)
DK (1) DK2687518T3 (pl)
ES (1) ES2652454T3 (pl)
HU (1) HUE037584T2 (pl)
MX (1) MX349484B (pl)
PH (1) PH12013501840A1 (pl)
PL (1) PL2687518T3 (pl)
PT (1) PT2687518T (pl)
RU (1) RU2595136C2 (pl)
TW (1) TWI597273B (pl)
WO (1) WO2012124775A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014042263A1 (ja) * 2012-09-14 2014-03-20 田辺三菱製薬株式会社 新規レニン阻害薬
JP5764628B2 (ja) * 2012-09-14 2015-08-19 田辺三菱製薬株式会社 医薬組成物
HUE059444T2 (hu) * 2015-12-29 2022-11-28 Shanghai Pharmaceuticals Holding Co Ltd Morfolinszármazék sója és ennek kristályformája, valamint ezek elõállítási eljárása, gyógyszerkészítménye és alkalmazása
CN109705052B (zh) * 2019-01-25 2020-12-08 苏州大学 一种制备1,4-二氢噁嗪的方法
EP4209218A4 (en) * 2020-09-04 2024-09-11 Shanghai Pharmaceuticals Holding Co., Ltd. Application of nitrogen-containing saturated heterocyclic compound
WO2022047730A1 (en) * 2020-09-04 2022-03-10 Shanghai Pharmaceuticals Holding Co., Ltd. Methods to treat inflammatory bowel disease
CN118084737A (zh) * 2024-04-07 2024-05-28 江苏工程职业技术学院 4-(1-((叔丁氧基羰基)氨基)环丁基)苯甲酸的合成方法
CN120365731B (zh) * 2025-06-04 2025-12-16 浙江福莱新材料股份有限公司 一种高强度阻燃隔音隔热复合材料及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0119797D0 (en) * 2001-08-14 2001-10-03 Glaxo Group Ltd Chemical compounds
GB0428526D0 (en) 2004-12-30 2005-02-09 Novartis Ag Organic compounds
GB0505969D0 (en) * 2005-03-23 2005-04-27 Novartis Ag Organic compounds
DE102005017116A1 (de) * 2005-04-13 2006-10-26 Novartis Ag Hemmstoffe für Inhibitoren von Apoptose Proteinen (IAP)
GB0511063D0 (en) 2005-05-31 2005-07-06 Novartis Ag Organic compounds
TWI452044B (zh) * 2007-06-15 2014-09-11 Mitsubishi Tanabe Pharma Corp 嗎啉衍生物
US8440693B2 (en) 2009-12-22 2013-05-14 Novartis Ag Substituted isoquinolinones and quinazolinones
WO2014042263A1 (ja) * 2012-09-14 2014-03-20 田辺三菱製薬株式会社 新規レニン阻害薬

Also Published As

Publication number Publication date
MX349484B (es) 2017-07-31
RU2013146012A (ru) 2015-05-27
BR112013023480A2 (pt) 2017-07-18
EP2687518A4 (en) 2014-08-20
RU2595136C2 (ru) 2016-08-20
ES2652454T3 (es) 2018-02-02
US20160145220A1 (en) 2016-05-26
HUE037584T2 (hu) 2018-09-28
CN103562191B (zh) 2016-03-30
KR101651722B1 (ko) 2016-08-26
CA2828378A1 (en) 2012-09-20
KR20130133294A (ko) 2013-12-06
CA2828378C (en) 2017-11-14
EP2687518A1 (en) 2014-01-22
AU2012229859B2 (en) 2015-07-16
US20140011807A1 (en) 2014-01-09
TWI597273B (zh) 2017-09-01
TW201242955A (en) 2012-11-01
JP5760078B2 (ja) 2015-08-05
PT2687518T (pt) 2018-01-19
US9278944B2 (en) 2016-03-08
AU2012229859C1 (en) 2020-01-16
CN103562191A (zh) 2014-02-05
BR112013023480A8 (pt) 2019-07-09
JPWO2012124775A1 (ja) 2014-07-24
AU2012229859A1 (en) 2013-09-19
PH12013501840A1 (en) 2016-06-17
DK2687518T3 (da) 2018-01-29
EP2687518B1 (en) 2017-11-01
BR112013023480B1 (pt) 2019-10-01
WO2012124775A1 (ja) 2012-09-20
US10155731B2 (en) 2018-12-18
MX2013010554A (es) 2013-12-02

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