PL2707396T3 - Biotechnologiczny siarczanowany siarczan chondroityny w pozycji 4 lub 6 na tym samym łańcuchu polisacharydowyn i sposób jego wytwarzania - Google Patents

Biotechnologiczny siarczanowany siarczan chondroityny w pozycji 4 lub 6 na tym samym łańcuchu polisacharydowyn i sposób jego wytwarzania

Info

Publication number: PL2707396T3
Authority: PL; Poland
Prior art keywords: biotechnological; preparation; chondroitin sulphate; polysaccharide chain; same polysaccharide
Prior art date: 2011-05-12

Application number

PL12725644T

Other languages

English (en)

Inventor

Davide Bianchi

Marco Valetti

Paola BAZZA

Niccolò MIRAGLIA

Ermanno Valoti

Original Assignee

Gnosis Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-12

Filing date

2012-05-10

Publication date

2019-04-30

2011-05-12 Priority claimed from IT000829A external-priority patent/ITMI20110829A1/it

2012-02-02 Priority claimed from IT000136A external-priority patent/ITMI20120136A1/it

2012-05-10 Application filed by Gnosis Spa filed Critical Gnosis Spa

2019-04-30 Publication of PL2707396T3 publication Critical patent/PL2707396T3/pl

Links

229920001287 Chondroitin sulfate Polymers 0.000 title 1
DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical class CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 title 1
150000004676 glycans Polymers 0.000 title 1
150000004804 polysaccharides Polymers 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Polymers & Plastics (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Materials Engineering (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PL12725644T 2011-05-12 2012-05-10 Biotechnologiczny siarczanowany siarczan chondroityny w pozycji 4 lub 6 na tym samym łańcuchu polisacharydowyn i sposób jego wytwarzania PL2707396T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IT000829A ITMI20110829A1 (it)	2011-05-12	2011-05-12	Condroitin solfato biotecnologico solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica e procedimento per la sua preparazione
IT000136A ITMI20120136A1 (it)	2012-02-02	2012-02-02	Condroitin solfato biotecnologico a basso peso molecolare solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica dotato di attivita' antiinfiammatoria e antiartritica e procedimento per la sua preparazione
PCT/EP2012/058654 WO2012152872A1 (en)	2011-05-12	2012-05-10	"biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof"
EP12725644.4A EP2707396B1 (en)	2011-05-12	2012-05-10	Biotechnological sulphated chondroitin sulphate at position 4 or 6 on the same polysaccharide chain, and process for the preparation thereof

Publications (1)

Publication Number	Publication Date
PL2707396T3 true PL2707396T3 (pl)	2019-04-30

Family

ID=46208441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12725644T PL2707396T3 (pl)	2011-05-12	2012-05-10	Biotechnologiczny siarczanowany siarczan chondroityny w pozycji 4 lub 6 na tym samym łańcuchu polisacharydowyn i sposób jego wytwarzania

Country Status (26)

Country	Link
US (2)	US20140315854A1 (pl)
EP (1)	EP2707396B1 (pl)
JP (1)	JP6205350B2 (pl)
KR (1)	KR101883910B1 (pl)
CN (1)	CN103582653B (pl)
AU (1)	AU2012252415B2 (pl)
BR (1)	BR112013027389B1 (pl)
CA (1)	CA2835498C (pl)
CY (1)	CY1121099T1 (pl)
DK (1)	DK2707396T3 (pl)
EA (1)	EA023849B1 (pl)
ES (1)	ES2705734T3 (pl)
GE (1)	GEP201606591B (pl)
HR (1)	HRP20190183T1 (pl)
HU (1)	HUE042378T2 (pl)
IL (1)	IL229367A (pl)
LT (1)	LT2707396T (pl)
MX (1)	MX351660B (pl)
PH (1)	PH12013502288A1 (pl)
PL (1)	PL2707396T3 (pl)
PT (1)	PT2707396T (pl)
RS (1)	RS58293B1 (pl)
SG (1)	SG194898A1 (pl)
SI (1)	SI2707396T1 (pl)
WO (1)	WO2012152872A1 (pl)
ZA (1)	ZA201308458B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITMI20130117A1 (it)	2013-01-25	2014-07-26	Gnosis Spa	Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato
CZ2014451A3 (cs) *	2014-06-30	2016-01-13	Contipro Pharma A.S.	Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
CN111662394B (zh) *	2019-03-05	2022-11-04	中国医学科学院药物研究所	硫酸软骨素多糖半合成制备方法和应用
IT201900008409A1 (it)	2019-06-07	2020-12-07	Vivatis Pharma Gmbh	Individuazione e selezione di un materiale di partenza vegetale di condroitina solfato e acido ialuronico vegetali, e trasformazione di tale materiale di partenza vegetale per l’ottenimento di ingredienti per utilizzo in alimenti, integratori, dispositivi medici o farmaci
IT202000013618A1 (it)	2020-06-08	2021-12-08	Vivatis Pharma Gmbh	Processo di estrazione di un acido ialuronico da un fungo, un acido ialuronico di origine vegetale e suo uso
IT202000013633A1 (it)	2020-06-08	2021-12-08	Vivatis Pharma Gmbh	Processo di estrazione di una condroitina solfato da un fungo, una condroitina solfato di origine vegetale e suo uso
CN119708287B (zh) *	2024-11-28	2025-11-18	复旦大学	一种用于治疗心肌梗塞的化合物
CN120554548A (zh) *	2025-03-18	2025-08-29	烟台东诚药业集团股份有限公司	一种硫酸软骨素钠的制备方法及其应用

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US3405120A (en) *	1966-01-27	1968-10-08	Green Cross Corp	Low molecular chondroitin sulfate and method for manufacturing the same
US4704356A (en) *	1984-03-27	1987-11-03	Rush-Presbyterian-St. Luke's Medical Center	Method of diagnosing cartilage tissue abnormalities
JPS6144822A (ja) *	1984-08-09	1986-03-04	Seikagaku Kogyo Co Ltd	コンドロイチン硫酸含有抗疲労剤
JPH0699485B2 (ja) *	1984-08-14	1994-12-07	生化学工業株式会社	合成コンドロイチン多硫酸の製造法
US5856174A (en)	1995-06-29	1999-01-05	Affymetrix, Inc.	Integrated nucleic acid diagnostic device
JP4258856B2 (ja) *	1998-03-06	2009-04-30	ニプロ株式会社	抗癌性複合体
ITMI20012200A1 (it) *	2001-10-22	2003-04-22	Ibsa Inst Biochimique Sa	Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti
JP2003128705A (ja) *	2001-10-29	2003-05-08	Kyowa Technos:Kk	低分子キトサンおよびその製造方法
JP4317350B2 (ja) *	2002-06-12	2009-08-19	生化学工業株式会社	顆粒球マクロファージコロニー刺激因子分泌促進剤
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JP4567942B2 (ja) *	2002-12-27	2010-10-27	生化学工業株式会社	破骨細胞形成抑制剤
JP4914594B2 (ja) *	2005-09-29	2012-04-11	ユニテックフーズ株式会社	関節痛改善用食品組成物
CN1789287A (zh) *	2005-12-20	2006-06-21	山东大学	一种多硫酸化硫酸软骨素及其制备方法
WO2009044765A1 (ja) *	2007-10-01	2009-04-09	Seikagaku Corporation	新規な低分子化コンドロイチン硫酸およびその用途
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JP5435538B2 (ja) *	2008-09-25	2014-03-05	国立大学法人鳥取大学	コンドロイチン硫酸の低分子化物の製造方法
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2012
- 2012-05-10 MX MX2013013181A patent/MX351660B/es active IP Right Grant
- 2012-05-10 KR KR1020137029882A patent/KR101883910B1/ko not_active Expired - Fee Related
- 2012-05-10 CA CA2835498A patent/CA2835498C/en active Active
- 2012-05-10 EP EP12725644.4A patent/EP2707396B1/en active Active
- 2012-05-10 PT PT12725644T patent/PT2707396T/pt unknown
- 2012-05-10 SI SI201231511T patent/SI2707396T1/sl unknown
- 2012-05-10 RS RS20190078A patent/RS58293B1/sr unknown
- 2012-05-10 SG SG2013083456A patent/SG194898A1/en unknown
- 2012-05-10 CN CN201280022676.XA patent/CN103582653B/zh active Active
- 2012-05-10 WO PCT/EP2012/058654 patent/WO2012152872A1/en not_active Ceased
- 2012-05-10 LT LTEP12725644.4T patent/LT2707396T/lt unknown
- 2012-05-10 US US14/115,184 patent/US20140315854A1/en not_active Abandoned
- 2012-05-10 PH PH1/2013/502288A patent/PH12013502288A1/en unknown
- 2012-05-10 HU HUE12725644A patent/HUE042378T2/hu unknown
- 2012-05-10 BR BR112013027389-5A patent/BR112013027389B1/pt active IP Right Grant
- 2012-05-10 ES ES12725644T patent/ES2705734T3/es active Active
- 2012-05-10 HR HRP20190183TT patent/HRP20190183T1/hr unknown
- 2012-05-10 JP JP2014509734A patent/JP6205350B2/ja not_active Expired - Fee Related
- 2012-05-10 PL PL12725644T patent/PL2707396T3/pl unknown
- 2012-05-10 EA EA201391673A patent/EA023849B1/ru not_active IP Right Cessation
- 2012-05-10 GE GEAP201213319A patent/GEP201606591B/en unknown
- 2012-05-10 AU AU2012252415A patent/AU2012252415B2/en active Active
- 2012-05-10 DK DK12725644.4T patent/DK2707396T3/en active
2013
- 2013-11-11 ZA ZA2013/08458A patent/ZA201308458B/en unknown
- 2013-11-11 IL IL229367A patent/IL229367A/en active IP Right Grant
2015
- 2015-12-21 US US14/977,119 patent/US9908947B2/en active Active
2019
- 2019-01-07 CY CY191100014T patent/CY1121099T1/el unknown

Also Published As

Publication number	Publication date
DK2707396T3 (en)	2019-01-28
MX2013013181A (es)	2013-12-12
US9908947B2 (en)	2018-03-06
KR20140034790A (ko)	2014-03-20
US20160108139A1 (en)	2016-04-21
PH12013502288A1 (en)	2014-01-06
EA201391673A1 (ru)	2014-03-31
JP6205350B2 (ja)	2017-09-27
GEP201606591B (en)	2017-01-10
KR101883910B1 (ko)	2018-08-01
BR112013027389B1 (pt)	2021-06-01
CN103582653B (zh)	2016-08-17
RS58293B1 (sr)	2019-03-29
ZA201308458B (en)	2015-02-25
CA2835498C (en)	2019-06-25
AU2012252415B2 (en)	2016-11-24
LT2707396T (lt)	2019-01-10
IL229367A0 (en)	2014-01-30
HRP20190183T1 (hr)	2019-03-22
HUE042378T2 (hu)	2019-06-28
CY1121099T1 (el)	2019-12-11
CN103582653A (zh)	2014-02-12
SI2707396T1 (sl)	2019-02-28
ES2705734T3 (es)	2019-03-26
JP2014514424A (ja)	2014-06-19
AU2012252415A1 (en)	2013-11-28
BR112013027389A2 (pt)	2017-01-17
SG194898A1 (en)	2013-12-30
EP2707396B1 (en)	2018-11-14
NZ617564A (en)	2015-06-26
WO2012152872A1 (en)	2012-11-15
CA2835498A1 (en)	2012-11-15
IL229367A (en)	2016-11-30
US20140315854A1 (en)	2014-10-23
EA023849B1 (ru)	2016-07-29
EP2707396A1 (en)	2014-03-19
PT2707396T (pt)	2019-01-23
MX351660B (es)	2017-10-23

Publication	Publication Date	Title
IL229367A (en)	2016-11-30	Chondroitin sulfate biotechnologically conserved in sulfate at position 4 or 6 on the same polysaccharide chain and process for preparation
LT2911699T (lt)	2018-03-26	Modifikuotas antikūnas, antikūnų konjugatas ir jų gavimo būdas
EP2877905A4 (en)	2017-08-02	Neural processing engine and architecture using the same
SG11201406021PA (en)	2014-10-30	Magnesium-aluminum-zinc alloy, method for the production thereof and use thereof
BR112013013806A2 (pt)	2016-09-13	artigos de vitrificação de redução de ofuscamento
EP2925643A4 (en)	2017-01-04	Side-flexing conveyors
PL2678331T3 (pl)	2016-12-30	Pochodne diaminopirymidyny i sposoby ich wytwarzania
PL2650310T3 (pl)	2017-01-31	Przeciwciało przeciw-ADAMTS-5, jego pochodne i zastosowania
PL2839099T3 (pl)	2018-01-31	Zamknięcie wahadłowe dla drzwi, okien lub tym podobnych
GB201506637D0 (en)	2015-06-03	Printing method and printing products employing the method thereof
IL229432A0 (en)	2014-01-30	Chondroitin sulfate domi-shark and a process for its preparation
PT2861673T (pt)	2023-11-13	Corantes reactivos sem metal, processo para a sua produção e sua utilização
PL393268A1 (pl)	2012-06-18	Kwas 2-amino-6-dihydroksyborylo-1,2,3,4-tetrahydronaftaleno-2-karboksylowy i sposób jego wytwarzania
PT2875076T (pt)	2018-11-23	Corantes reativos, processo para a sua produção e seu uso
ZA201308457B (en)	2015-02-25	Shark-like chondroitin sulphate and process for the preparation thereof
PL392177A1 (pl)	2011-02-14	Nowy aldehyd S-(+)-(5,5-dimetylocykloheks-2-en-1-ylo)octowy i sposób jego otrzymywania
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