PL2710015T3 - Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania - Google Patents
Odmiany polimorficzne ryfaksyminy i proces ich przygotowywaniaInfo
- Publication number
- PL2710015T3 PL2710015T3 PL12731691T PL12731691T PL2710015T3 PL 2710015 T3 PL2710015 T3 PL 2710015T3 PL 12731691 T PL12731691 T PL 12731691T PL 12731691 T PL12731691 T PL 12731691T PL 2710015 T3 PL2710015 T3 PL 2710015T3
- Authority
- PL
- Poland
- Prior art keywords
- rifaximin
- polymorph
- preparation
- Prior art date
Links
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 title 1
- 229960003040 rifaximin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000890A ITMI20110890A1 (it) | 2011-05-19 | 2011-05-19 | Polimorfo di rifaximina e processo per la sua preparazione |
| EP12731691.7A EP2710015B1 (en) | 2011-05-19 | 2012-05-18 | Polymorph of rifaximin and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2710015T3 true PL2710015T3 (pl) | 2017-08-31 |
Family
ID=44533008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12731691T PL2710015T3 (pl) | 2011-05-19 | 2012-05-18 | Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8877770B2 (pl) |
| EP (1) | EP2710015B1 (pl) |
| KR (2) | KR20140045413A (pl) |
| CN (1) | CN103619852B (pl) |
| AU (1) | AU2012257360B2 (pl) |
| BR (1) | BR112013029804A2 (pl) |
| CA (1) | CA2844765C (pl) |
| ES (1) | ES2586124T3 (pl) |
| IT (1) | ITMI20110890A1 (pl) |
| MX (1) | MX348393B (pl) |
| PL (1) | PL2710015T3 (pl) |
| PT (1) | PT2710015T (pl) |
| RU (1) | RU2593750C2 (pl) |
| SI (1) | SI2710015T1 (pl) |
| WO (1) | WO2012156951A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1698630E (pt) | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| US9018684B2 (en) | 2009-11-23 | 2015-04-28 | California Institute Of Technology | Chemical sensing and/or measuring devices and methods |
| IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
| ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
| EA032705B1 (ru) | 2013-04-12 | 2019-07-31 | Альфасигма С.П.А. | Способ лечения или предупреждения энтеропатии |
| US9419667B2 (en) | 2013-04-16 | 2016-08-16 | Skyworks Solutions, Inc. | Apparatus and methods related to conformal coating implemented with surface mount devices |
| ITMI20131307A1 (it) | 2013-08-02 | 2015-02-02 | A M S A Anonima Materie Sint & Affini S P A | Processo per la preparazione di refaximina k |
| ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
| DK3546464T3 (da) | 2014-05-12 | 2020-07-27 | Alfasigma Spa | Fremstilling og anvendelse af den krystallinske form tau af rifaximin solvateret med degme |
| CN106632396B (zh) * | 2017-01-06 | 2019-01-11 | 成都樵枫科技发展有限公司 | γ晶型利福昔明的制备方法和用途 |
| CN117447487A (zh) * | 2022-07-19 | 2024-01-26 | 重庆圣华曦药业股份有限公司 | 一种利福昔明的纯化方法及其在利福昔明片剂中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1154655B (it) * | 1980-05-22 | 1987-01-21 | Alfa Farmaceutici Spa | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
| ITMI20032144A1 (it) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
| PT1698630E (pt) * | 2005-03-03 | 2014-09-15 | Alfa Wassermann Spa | Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais |
| US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
| US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| GEP20135898B (en) * | 2008-02-25 | 2013-08-12 | Salix Pharmaceuticals Ltd | Rifaximin forms and usage |
-
2011
- 2011-05-19 IT IT000890A patent/ITMI20110890A1/it unknown
-
2012
- 2012-05-18 SI SI201230663A patent/SI2710015T1/sl unknown
- 2012-05-18 CN CN201280024381.6A patent/CN103619852B/zh active Active
- 2012-05-18 BR BR112013029804A patent/BR112013029804A2/pt not_active IP Right Cessation
- 2012-05-18 CA CA2844765A patent/CA2844765C/en active Active
- 2012-05-18 ES ES12731691.7T patent/ES2586124T3/es active Active
- 2012-05-18 KR KR1020137033427A patent/KR20140045413A/ko not_active Ceased
- 2012-05-18 MX MX2013013465A patent/MX348393B/es active IP Right Grant
- 2012-05-18 RU RU2013156344/04A patent/RU2593750C2/ru active
- 2012-05-18 PT PT127316917T patent/PT2710015T/pt unknown
- 2012-05-18 KR KR1020187007932A patent/KR20180032677A/ko not_active Ceased
- 2012-05-18 US US14/118,740 patent/US8877770B2/en active Active
- 2012-05-18 EP EP12731691.7A patent/EP2710015B1/en active Active
- 2012-05-18 AU AU2012257360A patent/AU2012257360B2/en active Active
- 2012-05-18 PL PL12731691T patent/PL2710015T3/pl unknown
- 2012-05-18 WO PCT/IB2012/052506 patent/WO2012156951A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| RU2013156344A (ru) | 2015-06-27 |
| ITMI20110890A1 (it) | 2012-11-20 |
| CA2844765A1 (en) | 2012-11-22 |
| CN103619852A (zh) | 2014-03-05 |
| MX348393B (es) | 2017-06-08 |
| WO2012156951A1 (en) | 2012-11-22 |
| CN103619852B (zh) | 2016-08-24 |
| US8877770B2 (en) | 2014-11-04 |
| AU2012257360B2 (en) | 2016-12-01 |
| SI2710015T1 (sl) | 2016-09-30 |
| KR20180032677A (ko) | 2018-03-30 |
| EP2710015A1 (en) | 2014-03-26 |
| BR112013029804A2 (pt) | 2016-09-06 |
| RU2593750C2 (ru) | 2016-08-10 |
| KR20140045413A (ko) | 2014-04-16 |
| EP2710015B1 (en) | 2016-05-18 |
| MX2013013465A (es) | 2014-05-27 |
| CA2844765C (en) | 2019-07-16 |
| US20140107144A1 (en) | 2014-04-17 |
| ES2586124T3 (es) | 2016-10-11 |
| BR112013029706A2 (pt) | 2021-07-27 |
| PT2710015T (pt) | 2016-08-25 |
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