PL2710015T3 - Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania - Google Patents

Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania

Info

Publication number
PL2710015T3
PL2710015T3 PL12731691T PL12731691T PL2710015T3 PL 2710015 T3 PL2710015 T3 PL 2710015T3 PL 12731691 T PL12731691 T PL 12731691T PL 12731691 T PL12731691 T PL 12731691T PL 2710015 T3 PL2710015 T3 PL 2710015T3
Authority
PL
Poland
Prior art keywords
rifaximin
polymorph
preparation
Prior art date
Application number
PL12731691T
Other languages
English (en)
Inventor
Enrico Vigano'
Renato Molteni
Simona Lanfranconi
Massimiliano Arrighi
Fabio Gatti
Original Assignee
Clarochem Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clarochem Ireland Limited filed Critical Clarochem Ireland Limited
Publication of PL2710015T3 publication Critical patent/PL2710015T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL12731691T 2011-05-19 2012-05-18 Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania PL2710015T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000890A ITMI20110890A1 (it) 2011-05-19 2011-05-19 Polimorfo di rifaximina e processo per la sua preparazione
EP12731691.7A EP2710015B1 (en) 2011-05-19 2012-05-18 Polymorph of rifaximin and process for the preparation thereof

Publications (1)

Publication Number Publication Date
PL2710015T3 true PL2710015T3 (pl) 2017-08-31

Family

ID=44533008

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12731691T PL2710015T3 (pl) 2011-05-19 2012-05-18 Odmiany polimorficzne ryfaksyminy i proces ich przygotowywania

Country Status (15)

Country Link
US (1) US8877770B2 (pl)
EP (1) EP2710015B1 (pl)
KR (2) KR20140045413A (pl)
CN (1) CN103619852B (pl)
AU (1) AU2012257360B2 (pl)
BR (1) BR112013029804A2 (pl)
CA (1) CA2844765C (pl)
ES (1) ES2586124T3 (pl)
IT (1) ITMI20110890A1 (pl)
MX (1) MX348393B (pl)
PL (1) PL2710015T3 (pl)
PT (1) PT2710015T (pl)
RU (1) RU2593750C2 (pl)
SI (1) SI2710015T1 (pl)
WO (1) WO2012156951A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1698630T1 (sl) 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
US9018684B2 (en) 2009-11-23 2015-04-28 California Institute Of Technology Chemical sensing and/or measuring devices and methods
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
AU2014252219B2 (en) 2013-04-12 2018-11-22 Alfasigma S.P.A. NSAID administration and related compositions, methods and systems.
US9419667B2 (en) 2013-04-16 2016-08-16 Skyworks Solutions, Inc. Apparatus and methods related to conformal coating implemented with surface mount devices
ITMI20131307A1 (it) 2013-08-02 2015-02-02 A M S A Anonima Materie Sint & Affini S P A Processo per la preparazione di refaximina k
ES2621557T3 (es) 2014-03-31 2017-07-04 Euticals S.P.A. Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas
PT3546464T (pt) 2014-05-12 2020-08-05 Alfasigma Spa Preparação e utilização da forma cristalina tau de rifaximina solvatada com degme
CN106632396B (zh) * 2017-01-06 2019-01-11 成都樵枫科技发展有限公司 γ晶型利福昔明的制备方法和用途
CN117447487A (zh) * 2022-07-19 2024-01-26 重庆圣华曦药业股份有限公司 一种利福昔明的纯化方法及其在利福昔明片剂中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1154655B (it) 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
SI1698630T1 (sl) * 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
WO2009108730A2 (en) * 2008-02-25 2009-09-03 Salix Pharmaceuticals, Ltd. Forms of rifaximin and uses thereof
US8486956B2 (en) * 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof

Also Published As

Publication number Publication date
CN103619852A (zh) 2014-03-05
BR112013029804A2 (pt) 2016-09-06
CA2844765A1 (en) 2012-11-22
RU2013156344A (ru) 2015-06-27
PT2710015T (pt) 2016-08-25
EP2710015B1 (en) 2016-05-18
AU2012257360B2 (en) 2016-12-01
CN103619852B (zh) 2016-08-24
CA2844765C (en) 2019-07-16
US20140107144A1 (en) 2014-04-17
KR20140045413A (ko) 2014-04-16
MX2013013465A (es) 2014-05-27
RU2593750C2 (ru) 2016-08-10
EP2710015A1 (en) 2014-03-26
BR112013029706A2 (pt) 2021-07-27
US8877770B2 (en) 2014-11-04
ITMI20110890A1 (it) 2012-11-20
MX348393B (es) 2017-06-08
WO2012156951A1 (en) 2012-11-22
SI2710015T1 (sl) 2016-09-30
ES2586124T3 (es) 2016-10-11
KR20180032677A (ko) 2018-03-30

Similar Documents

Publication Publication Date Title
IL221299A (en) A process for the preparation of Rifaximine pallimorphic configuration
IL246265B (en) A method for the production of intermediates for the preparation of 5-fluoro-h1-pyrazolopyridines and such compounds
ZA201206095B (en) Process for the preparation of isoxazoline derivatives
ZA201305972B (en) Method for the preparation of biphephos
SI2710015T1 (sl) Polimorf rifaximina in postopek za njegovo pripravo
PL2531286T3 (pl) Sposób syntezy metanolu
ZA201204365B (en) Darunavir polymorph and process for preparation thereof
ZA201305582B (en) Process for the preparation of 4-amino-5-fluoro-3-halo-6-(sunstituted)picolinates
IL232625B (en) Process for making trouver frost
SG11201400939YA (en) Process for the preparation of methoxymelonal
GB2560284B (en) Process for the 3-O-demethylation of morphinan compounds
ZA201403736B (en) Process for the preparation of sterol derivatives
IL232424A (en) Process for the preparation of 1-noble-4-phenylsulfonylprolinamide and intermediates
ZA201207397B (en) Process for the preparation of dexlansoprazole
ZA201309713B (en) Process for the preparation of paliperidone
EP2596007A4 (en) PROCESS FOR THE PREPARATION OF 17-DEOXY-CORTICOSTEROIDS
ZA201300546B (en) Process for the preparation of 3-haloalkylpyrazoles
GB201119690D0 (en) Process for the preparation of compounds
SG11201400090UA (en) Process for the preparation of olefins
PT2603319E (pt) Processo para a preparação de uretanos
PL393916A1 (pl) Sposób wytwarzania związków karbapenamowych
PT2390246T (pt) Processo para a preparação de aminaftona
PL2702045T3 (pl) Nowy sposób sporządzania Etrawiryny
ZA201309732B (en) Process for the preparation of dexlansoprazole
PL2710014T3 (pl) Sposób syntezy rifaksyminy