PL2742051T3 - Amorficzna postać soli sodowej dolutegrawiru - Google Patents
Amorficzna postać soli sodowej dolutegrawiruInfo
- Publication number
- PL2742051T3 PL2742051T3 PL12831486T PL12831486T PL2742051T3 PL 2742051 T3 PL2742051 T3 PL 2742051T3 PL 12831486 T PL12831486 T PL 12831486T PL 12831486 T PL12831486 T PL 12831486T PL 2742051 T3 PL2742051 T3 PL 2742051T3
- Authority
- PL
- Poland
- Prior art keywords
- amorpous
- sodium salt
- dolutegravir sodium
- dolutegravir
- salt
- Prior art date
Links
- UGWJRRXTMKRYNK-VSLILLSYSA-M dolutegravir sodium Chemical compound [Na+].C([C@@H]1OCC[C@H](N1C(=O)C1=C([O-])C2=O)C)N1C=C2C(=O)NCC1=CC=C(F)C=C1F UGWJRRXTMKRYNK-VSLILLSYSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161534395P | 2011-09-14 | 2011-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2742051T3 true PL2742051T3 (pl) | 2017-06-30 |
Family
ID=47882703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12831486T PL2742051T3 (pl) | 2011-09-14 | 2012-09-02 | Amorficzna postać soli sodowej dolutegrawiru |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9206197B2 (pl) |
| EP (1) | EP2742051B1 (pl) |
| ES (1) | ES2613180T3 (pl) |
| PL (1) | PL2742051T3 (pl) |
| WO (1) | WO2013038407A1 (pl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2893843C (en) | 2012-12-21 | 2018-09-04 | Gilead Sciences, Inc. | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
| EP2956123A1 (en) | 2013-02-18 | 2015-12-23 | ratiopharm GmbH | Solid pharmaceutical dosage form of dolutegravir |
| EP2767272A1 (en) * | 2013-02-18 | 2014-08-20 | Ratiopharm GmbH | Solid pharmaceutical dosage form of dolutegravir |
| NO2865735T3 (pl) | 2013-07-12 | 2018-07-21 | ||
| DK3019503T3 (da) | 2013-07-12 | 2017-11-20 | Gilead Sciences Inc | Polycykliske-carbamoylpyridon-forbindelser og anvendelse deraf til behandling af hiv-infektioner |
| EP3022209B1 (en) | 2013-07-17 | 2018-03-07 | ratiopharm GmbH | Dolutegravir potassium salt |
| EP3033084A1 (en) * | 2013-08-14 | 2016-06-22 | ratiopharm GmbH | Medicament comprising a pharmaceutical combination of dolutegravir, emtricitabine and tenofovir |
| WO2015092752A1 (en) | 2013-12-20 | 2015-06-25 | Mylan Laboratories Ltd. | Novel crystalline form of dolutegravir sodium |
| IN2014MU00455A (pl) | 2014-02-07 | 2015-09-25 | Mylan Lab Ltd | |
| CN107056813B (zh) * | 2014-03-19 | 2019-07-30 | 杭州普晒医药科技有限公司 | 德罗格韦钠盐的晶型及其制备方法 |
| WO2015140569A1 (en) * | 2014-03-20 | 2015-09-24 | Cipla Limited | Pharmaceutical composition |
| TW201613936A (en) | 2014-06-20 | 2016-04-16 | Gilead Sciences Inc | Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide |
| TWI677489B (zh) | 2014-06-20 | 2019-11-21 | 美商基利科學股份有限公司 | 多環型胺甲醯基吡啶酮化合物之合成 |
| NO2717902T3 (pl) * | 2014-06-20 | 2018-06-23 | ||
| EP2980091A1 (en) | 2014-07-29 | 2016-02-03 | LEK Pharmaceuticals d.d. | Novel hydrates of dolutegravir sodium |
| WO2016016279A1 (en) * | 2014-07-29 | 2016-02-04 | Lek Pharmaceuticals D.D. | Novel hydrates of dolutegravir sodium |
| TWI738321B (zh) | 2014-12-23 | 2021-09-01 | 美商基利科學股份有限公司 | 多環胺甲醯基吡啶酮化合物及其醫藥用途 |
| CZ201599A3 (cs) | 2015-02-13 | 2016-08-24 | Zentiva, K.S. | Pevné formy solí dolutegraviru a způsob jejich přípravy |
| TR201905009T4 (tr) | 2015-04-02 | 2019-05-21 | Gilead Sciences Inc | Polisiklik-karbamoilpiridon bileşikleri ve bunların farmasötik kullanımları. |
| CZ2015537A3 (cs) | 2015-08-04 | 2017-02-15 | Zentiva, K.S. | Pevné formy amorfního dolutegraviru |
| US10597404B2 (en) | 2015-08-19 | 2020-03-24 | Laurus Labs Ltd. | Polymorphs of dolutegravir and salts thereof |
| WO2017208105A1 (en) | 2016-05-30 | 2017-12-07 | Lupin Limited | Novel crystalline form of dolutegravir sodium |
| JOP20190130A1 (ar) | 2016-12-02 | 2019-06-02 | Merck Sharp & Dohme | مركبات حلقية غير متجانسة رباعية الحلقات مفيدة كمثبطات إنزيم مدمج لفيروس نقص المناعة البشرية (hiv) |
| CN110958883A (zh) | 2017-06-30 | 2020-04-03 | Viiv保健公司 | 组合及其用途和疗法 |
| US20210040116A1 (en) | 2017-09-07 | 2021-02-11 | Cipla Limited | New Polymorphs of Dolutegravir Sodium |
| US20200398978A1 (en) | 2019-06-20 | 2020-12-24 | Bell Helicopter Textron Inc. | Low-drag rotor blade extension |
| CN114213432B (zh) * | 2021-12-31 | 2023-02-17 | 瑞孚信江苏药业股份有限公司 | 度鲁特韦的制备方法 |
| CN114394981B (zh) * | 2022-01-05 | 2023-06-20 | 华东理工大学 | 多替拉韦钠微流控连续结晶方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1874117E (pt) | 2005-04-28 | 2013-10-17 | Shionogi & Co | Derivado policíclico de carbamoílpiridona possuindo actividade inibidora de hiv-integrasse |
| WO2010011819A1 (en) | 2008-07-25 | 2010-01-28 | Smithkline Beecham Corporation | Chemical compounds |
| SI2320908T1 (sl) | 2008-07-25 | 2014-05-30 | Viiv Healthcare Company | Predzdravila dolutegravirja |
| KR101733625B1 (ko) | 2008-12-11 | 2017-05-10 | 시오노기세야쿠 가부시키가이샤 | 카르바모일피리돈 ｈｉｖ 인테그라제 억제제 및 중간체의 합성 |
-
2012
- 2012-09-02 US US14/344,737 patent/US9206197B2/en active Active
- 2012-09-02 WO PCT/IL2012/050344 patent/WO2013038407A1/en not_active Ceased
- 2012-09-02 ES ES12831486.1T patent/ES2613180T3/es active Active
- 2012-09-02 PL PL12831486T patent/PL2742051T3/pl unknown
- 2012-09-02 EP EP12831486.1A patent/EP2742051B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140350004A1 (en) | 2014-11-27 |
| WO2013038407A1 (en) | 2013-03-21 |
| ES2613180T3 (es) | 2017-05-23 |
| EP2742051A4 (en) | 2015-03-18 |
| EP2742051A1 (en) | 2014-06-18 |
| EP2742051B1 (en) | 2016-10-12 |
| US9206197B2 (en) | 2015-12-08 |
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