PL2745091T3 - Długi sztywny odstępnik dla wzmacniania kinetyki wiązania w testach immunologicznych - Google Patents
Długi sztywny odstępnik dla wzmacniania kinetyki wiązania w testach immunologicznychInfo
- Publication number
- PL2745091T3 PL2745091T3 PL12799638T PL12799638T PL2745091T3 PL 2745091 T3 PL2745091 T3 PL 2745091T3 PL 12799638 T PL12799638 T PL 12799638T PL 12799638 T PL12799638 T PL 12799638T PL 2745091 T3 PL2745091 T3 PL 2745091T3
- Authority
- PL
- Poland
- Prior art keywords
- immunoassays
- binding kinetics
- enhance binding
- long rigid
- rigid spacers
- Prior art date
Links
- 238000003018 immunoassay Methods 0.000 title 1
- 125000006850 spacer group Chemical group 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161560441P | 2011-11-16 | 2011-11-16 | |
| EP11191454.5A EP2594942A1 (en) | 2011-11-16 | 2011-12-01 | Long rigid spacers to enhance binding kinetics in immunoassays |
| PCT/IB2012/056378 WO2013072842A1 (en) | 2011-11-16 | 2012-11-13 | Long rigid spacers to enhance binding kinetics in immunoassays |
| EP12799638.7A EP2745091B1 (en) | 2011-11-16 | 2012-11-13 | Long rigid spacers to enhance binding kinetics in immunoassays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2745091T3 true PL2745091T3 (pl) | 2016-04-29 |
Family
ID=45346267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12799638T PL2745091T3 (pl) | 2011-11-16 | 2012-11-13 | Długi sztywny odstępnik dla wzmacniania kinetyki wiązania w testach immunologicznych |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10942178B2 (pl) |
| EP (2) | EP2594942A1 (pl) |
| JP (1) | JP6173332B2 (pl) |
| CN (1) | CN103946686B (pl) |
| BR (1) | BR112014011514B8 (pl) |
| DK (1) | DK2745091T3 (pl) |
| ES (1) | ES2555904T3 (pl) |
| PL (1) | PL2745091T3 (pl) |
| RU (1) | RU2641032C2 (pl) |
| WO (1) | WO2013072842A1 (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2594940A1 (en) * | 2011-11-16 | 2013-05-22 | Koninklijke Philips Electronics N.V. | Particle repulsion to enhance surface contact in magnetic particle immunoassays |
| ES2636483T3 (es) * | 2012-02-21 | 2017-10-05 | Laboratory Corporation Of America Holdings | Métodos y sistemas para la amplificación de señal de bioensayos |
| CN105579849B (zh) | 2013-06-06 | 2019-02-22 | 微型照顾私人有限公司 | 在用于检测多聚靶分子的基于颗粒的测试中防止聚集的试剂、方法和设备 |
| WO2015134972A2 (en) | 2014-03-07 | 2015-09-11 | The Board Of Trustees Of The University Of Illinois | Biomimetic microfluid device for capturing circulating tumor cells |
| EP4009032A1 (en) * | 2014-04-21 | 2022-06-08 | Aber Instruments, Inc. | Particle sensor with interferent discrimination |
| WO2016048388A1 (en) | 2014-09-26 | 2016-03-31 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| JP6979941B2 (ja) * | 2015-08-20 | 2021-12-15 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Peg化分析物特異的結合剤を用いた粒子に基づくイムノアッセイ |
| JP7068323B2 (ja) * | 2017-02-02 | 2022-05-16 | エフ.ホフマン-ラ ロシュ アーゲー | 少なくとも2種のペグ化された分析物特異的結合剤を使用する免疫アッセイ |
| CN107727851A (zh) * | 2017-11-15 | 2018-02-23 | 北京舜雷科技有限公司 | 一种免疫凝集和胶体金层析试纸条相结合的用于检测hit抗体的系统 |
| US10739261B2 (en) * | 2018-04-30 | 2020-08-11 | Purdue Research Foundation | Surface-plasmon opto-magnetic field enhancement for all-optical magnetization switching |
| JP7225656B2 (ja) * | 2018-10-10 | 2023-02-21 | 凸版印刷株式会社 | 目的物質検出装置及び目的物質検出方法 |
| WO2020191602A1 (zh) * | 2019-03-25 | 2020-10-01 | 京东方科技集团股份有限公司 | 一种免疫检测芯片、免疫检测装置及使用方法 |
| CN112798778B (zh) * | 2021-03-17 | 2021-07-02 | 广州敏捷生物技术有限公司 | 同步检测禽蛋中氟苯尼考、甲氧苄啶含量的免疫荧光层析检测卡及方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DK51092D0 (da) * | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| US5635602A (en) * | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
| US5599668A (en) * | 1994-09-22 | 1997-02-04 | Abbott Laboratories | Light scattering optical waveguide method for detecting specific binding events |
| DE69737598T2 (de) * | 1996-07-29 | 2007-12-27 | Nanosphere Inc., Skokie | Nanopartikel mit daran angehefteten oligonukleotiden sowie deren verwendungen |
| WO2000068689A1 (en) * | 1999-05-10 | 2000-11-16 | Prolinx Inc. | Cell separation device and methods for use |
| CA2396113C (en) * | 2000-01-13 | 2009-04-07 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| WO2002079514A1 (en) * | 2001-01-10 | 2002-10-10 | The Trustees Of Boston College | Dna-bridged carbon nanotube arrays |
| WO2003096014A2 (en) * | 2002-05-08 | 2003-11-20 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Magneto-controlled method and system for determining an analyte in a liquid medium |
| US6790632B2 (en) * | 2002-06-17 | 2004-09-14 | Stephen Eliot Zweig | Membrane receptor reagent and assay |
| WO2004071641A2 (en) * | 2003-02-10 | 2004-08-26 | Pointilliste, Inc. | Self-assembling arrays and uses thereof |
| JP3878922B2 (ja) * | 2003-04-24 | 2007-02-07 | 独立行政法人科学技術振興機構 | 脂質セカンドメッセンジャー検出・定量用プローブとそれを用いた脂質セカンドメッセンジャーの検出および定量方法 |
| ES2661168T3 (es) * | 2003-07-12 | 2018-03-27 | Accelerate Diagnostics, Inc. | Biodetección sensible y rápida |
| WO2005012579A2 (en) * | 2003-07-31 | 2005-02-10 | Molecular Probes, Inc. | Homodimeric cyanine dye dimer comprising aromatic, heteroaromatic, cyclic or heterocyclic linker moiety in nucleic acid reporter molecules |
| US20100008618A1 (en) * | 2005-02-01 | 2010-01-14 | Swanson Basil I | Modulated optical waveguide sensor |
| GB0523366D0 (en) * | 2005-11-16 | 2005-12-28 | Univ Cardiff | Method |
| DE602006016984D1 (de) * | 2005-12-12 | 2010-10-28 | Us Gov Health & Human Serv | Sonde zum sequenzieren von nukleinsäure und verwendungsverfahren |
| EP1873344A1 (de) | 2006-06-30 | 2008-01-02 | Sika Technology AG | Mittels Silikon agedichtete Verklebung |
| EP2092339B1 (en) | 2006-12-12 | 2012-05-16 | Koninklijke Philips Electronics N.V. | Microelectronic sensor device for detecting label particles |
| US20100285490A1 (en) * | 2006-12-29 | 2010-11-11 | Invitrogen Corporation | Detection apparatus |
| WO2008116093A2 (en) * | 2007-03-20 | 2008-09-25 | Becton, Dickinson And Company | Assays using surface-enhanced raman spectroscopy (sers)-active particles |
| WO2008116468A2 (en) * | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
| US20100143905A1 (en) * | 2007-03-29 | 2010-06-10 | Lane Michael J | Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests |
| US20120164073A1 (en) * | 2007-11-30 | 2012-06-28 | Old Dominion University | Stable nanoparticles, nanoparticle-based imaging systems, nanoparticle-based assays, and in vivo assays for screening biocompatibility and toxicity of nanoparticles |
| US20090258355A1 (en) * | 2008-04-11 | 2009-10-15 | Brookhaven Science Associates, Llc | Nanoscale Clusters and Methods of Making Same |
| WO2009126336A1 (en) * | 2008-04-11 | 2009-10-15 | Becton, Dickinson And Company | Methods of controlling the sensitivity and dynamic range of a homogeneous assay |
| BRPI0918101A2 (pt) * | 2008-12-22 | 2015-11-24 | Koninkl Philips Electronics Nv | método para medir a troponina i em uma amostra, cartucho para ser utilizado em um dispositivo de ensaio e uso |
| CN101607974B (zh) * | 2009-07-16 | 2011-09-21 | 天津大学 | 一种葡萄糖探针及其制备方法和利用这种葡萄糖探针的糖芯片及其制备方法 |
| CN102597774B (zh) * | 2009-09-23 | 2015-05-13 | 皇家飞利浦电子股份有限公司 | 利用多种磁性标记示踪结合试剂的结合测定 |
| EP2483661B1 (en) | 2009-09-28 | 2020-02-05 | Koninklijke Philips N.V. | Substance determining apparatus and method |
| US8547533B2 (en) * | 2009-12-28 | 2013-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Composite probes and use thereof in super resolution methods |
| CN102947703A (zh) * | 2010-06-17 | 2013-02-27 | 皇家飞利浦电子股份有限公司 | 多表位测定 |
| WO2012018787A2 (en) | 2010-08-02 | 2012-02-09 | Adc Telecommunications, Inc. | Cable spool assembly |
| CN102040653B (zh) * | 2010-09-07 | 2013-07-31 | 湘潭大学 | 一种能与聚苯乙烯亲和结合的标签肽及其用于制备酶联免疫固相抗原的方法 |
| EP2541250A1 (en) * | 2011-06-30 | 2013-01-02 | Koninklijke Philips Electronics N.V. | Molecular architecture on magnetic particles for affinity assays with low non-specific binding |
| US9920295B2 (en) * | 2012-02-21 | 2018-03-20 | The Trustees Of The University Of Pennsylvania | Bioreactor for isolation of rare cells and methods of use |
| JP2013205159A (ja) * | 2012-03-28 | 2013-10-07 | Dainippon Printing Co Ltd | 親水性ポリマー層を有する物質固定化用担体 |
-
2011
- 2011-12-01 EP EP11191454.5A patent/EP2594942A1/en not_active Ceased
-
2012
- 2012-11-13 US US14/358,550 patent/US10942178B2/en active Active
- 2012-11-13 EP EP12799638.7A patent/EP2745091B1/en active Active
- 2012-11-13 DK DK12799638.7T patent/DK2745091T3/en active
- 2012-11-13 JP JP2014541790A patent/JP6173332B2/ja active Active
- 2012-11-13 PL PL12799638T patent/PL2745091T3/pl unknown
- 2012-11-13 RU RU2014124190A patent/RU2641032C2/ru active
- 2012-11-13 WO PCT/IB2012/056378 patent/WO2013072842A1/en not_active Ceased
- 2012-11-13 CN CN201280056479.XA patent/CN103946686B/zh active Active
- 2012-11-13 ES ES12799638.7T patent/ES2555904T3/es active Active
-
2013
- 2013-11-13 BR BR112014011514A patent/BR112014011514B8/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013072842A1 (en) | 2013-05-23 |
| ES2555904T3 (es) | 2016-01-11 |
| BR112014011514A2 (pt) | 2017-05-16 |
| EP2594942A1 (en) | 2013-05-22 |
| RU2014124190A (ru) | 2015-12-27 |
| WO2013072842A8 (en) | 2014-05-30 |
| JP2014533831A (ja) | 2014-12-15 |
| EP2745091B1 (en) | 2015-10-21 |
| DK2745091T3 (en) | 2015-12-14 |
| EP2745091A1 (en) | 2014-06-25 |
| BR112014011514B1 (pt) | 2020-09-15 |
| CN103946686B (zh) | 2017-03-15 |
| US20150177239A1 (en) | 2015-06-25 |
| US10942178B2 (en) | 2021-03-09 |
| JP6173332B2 (ja) | 2017-08-02 |
| BR112014011514B8 (pt) | 2022-12-20 |
| RU2641032C2 (ru) | 2018-01-15 |
| CN103946686A (zh) | 2014-07-23 |
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