PL2797898T3 - Pochodne piperazynylowe do leczenia nowotworów - Google Patents

Pochodne piperazynylowe do leczenia nowotworów

Info

Publication number
PL2797898T3
PL2797898T3 PL12808851T PL12808851T PL2797898T3 PL 2797898 T3 PL2797898 T3 PL 2797898T3 PL 12808851 T PL12808851 T PL 12808851T PL 12808851 T PL12808851 T PL 12808851T PL 2797898 T3 PL2797898 T3 PL 2797898T3
Authority
PL
Poland
Prior art keywords
cancers
treatment
piperazinyl derivatives
piperazinyl
derivatives
Prior art date
Application number
PL12808851T
Other languages
English (en)
Inventor
Denis Carniato
Jean-François Briand
Mathieu Gutmann
Olivier Busnel
Cécile Bougeret
Benoit Deprez
Karine Jaillardon
Original Assignee
Pitty, Marc-Henry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pitty, Marc-Henry filed Critical Pitty, Marc-Henry
Publication of PL2797898T3 publication Critical patent/PL2797898T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12808851T 2011-12-30 2012-12-28 Pochodne piperazynylowe do leczenia nowotworów PL2797898T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1162586A FR2985256B1 (fr) 2011-12-30 2011-12-30 Derives piperazinyles pour le traitement de cancers

Publications (1)

Publication Number Publication Date
PL2797898T3 true PL2797898T3 (pl) 2017-03-31

Family

ID=47470025

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12808851T PL2797898T3 (pl) 2011-12-30 2012-12-28 Pochodne piperazynylowe do leczenia nowotworów

Country Status (17)

Country Link
US (1) US9321778B2 (pl)
EP (1) EP2797898B9 (pl)
JP (1) JP6105625B2 (pl)
KR (1) KR102086732B1 (pl)
CN (1) CN104053648B (pl)
AU (1) AU2012360815B2 (pl)
BR (1) BR112014015991B1 (pl)
CA (1) CA2859721C (pl)
ES (1) ES2606289T3 (pl)
FR (1) FR2985256B1 (pl)
HU (1) HUE030951T2 (pl)
IL (1) IL233414A (pl)
PL (1) PL2797898T3 (pl)
RU (1) RU2629115C2 (pl)
SG (1) SG11201403727YA (pl)
WO (1) WO2013098393A1 (pl)
ZA (1) ZA201405068B (pl)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10358539A1 (de) * 2003-12-15 2005-07-07 Merck Patent Gmbh Carbonsäureamidderivate
US20060058296A1 (en) * 2003-12-24 2006-03-16 Scios, Inc. Treatment of osteolytic lesions associated with multiple myeloma by inhibition of p38 map kinase
US7838524B2 (en) * 2004-04-30 2010-11-23 Bayer Healthcare Llc Substituted pyrazolyl urea derivatives useful in the treatment of cancer
US7615556B2 (en) * 2006-01-27 2009-11-10 Bristol-Myers Squibb Company Piperazinyl derivatives as modulators of chemokine receptor activity
JP2010526048A (ja) * 2007-05-04 2010-07-29 アストラゼネカ アクチボラグ アミノ−チアゾリル−ピリミジン誘導体、および癌の治療のための該誘導体の使用
FR2932483A1 (fr) * 2008-06-13 2009-12-18 Cytomics Systems Composes utiles pour le traitement des cancers.
WO2010091164A1 (en) * 2009-02-06 2010-08-12 Exelixis, Inc. Inhibitors of glucosylceramide synthase
AU2010250923A1 (en) * 2009-05-21 2011-11-17 Astrazeneca Ab Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
CN103097340B (zh) * 2010-07-16 2018-03-16 安吉奥斯医药品有限公司 治疗活性组合物及其使用方法
WO2012129452A2 (en) 2011-03-22 2012-09-27 University Of Southern California Propynoic acid carbamoyl methyl-almides and pharmaceutical compositions and methods based thereon

Also Published As

Publication number Publication date
IL233414A (en) 2015-11-30
EP2797898B9 (fr) 2021-05-26
BR112014015991A8 (pt) 2017-07-04
FR2985256A1 (fr) 2013-07-05
WO2013098393A1 (fr) 2013-07-04
CA2859721A1 (fr) 2013-07-04
US20140356360A1 (en) 2014-12-04
EP2797898B1 (fr) 2016-09-14
SG11201403727YA (en) 2014-09-26
JP6105625B2 (ja) 2017-03-29
ES2606289T3 (es) 2017-03-23
ZA201405068B (en) 2015-11-25
HUE030951T2 (en) 2017-06-28
RU2014131001A (ru) 2016-02-20
KR102086732B1 (ko) 2020-03-09
NZ627149A (en) 2015-08-28
US9321778B2 (en) 2016-04-26
CA2859721C (fr) 2020-01-07
BR112014015991A2 (pt) 2017-06-13
FR2985256B1 (fr) 2016-03-04
CN104053648A (zh) 2014-09-17
RU2629115C2 (ru) 2017-08-24
AU2012360815B2 (en) 2017-02-02
BR112014015991B1 (pt) 2022-11-16
IL233414A0 (en) 2014-08-31
HK1202118A1 (en) 2015-09-18
EP2797898A1 (fr) 2014-11-05
JP2015505308A (ja) 2015-02-19
CN104053648B (zh) 2016-09-28
AU2012360815A1 (en) 2014-07-31
KR20140117456A (ko) 2014-10-07

Similar Documents

Publication Publication Date Title
HUS1900040I1 (hu) Makrociklusos származékok proliferatív betegségek kezelésére
IL235726A0 (en) Pyrimidine compounds for cancer treatment
IL232530A0 (en) Combined cancer treatment
HUE047198T2 (hu) Fitokannabinoidok emlõrák kezelésére
EP2751267A4 (en) METHOD FOR THE TREATMENT OF BREAST CANCER
IL228430A0 (en) Cancer treatment
IL236008B (en) Coenzyme Q10 for the treatment of solid tumors
EP2903644A4 (en) TREATMENT OF CANCER
GB201217892D0 (en) Treatment of cancer
HUE038327T2 (hu) Tüdõrák kezelése a SMAD3 inhibitor SIS3 felhasználásával
IL275636A (en) Medical combination for cancer treatment
PL2817286T3 (pl) Inhibitory kinazy do leczenia raka
PL2855475T3 (pl) Alfa-karboliny do leczenia nowotworu
IL233493A (en) Imidazopyridine derivatives for cancer treatment
ZA201400488B (en) Compounds for the treatment of cancers associated with human papillomavirus
IL236870B (en) History of hydroxystatin for the treatment of osteoarthritis
ZA201405068B (en) Piperazinyl derivatives for the treatment of cancer
GB201217890D0 (en) Treatment of cancer
HUE048942T2 (hu) Antraciklin-származékok tumorbetegségek kezeléséhez
GB201121791D0 (en) Combination treatment of cancer
GB201121783D0 (en) Treatment of cancer
AU2012901199A0 (en) Kinase inhibitors for the Treatment of Cancer
GB201208296D0 (en) Treatment of cancer
GB201200262D0 (en) Therapy of breast cancer