PL2797898T3 - Pochodne piperazynylowe do leczenia nowotworów - Google Patents

Pochodne piperazynylowe do leczenia nowotworów

Info

Publication number
PL2797898T3
PL2797898T3 PL12808851T PL12808851T PL2797898T3 PL 2797898 T3 PL2797898 T3 PL 2797898T3 PL 12808851 T PL12808851 T PL 12808851T PL 12808851 T PL12808851 T PL 12808851T PL 2797898 T3 PL2797898 T3 PL 2797898T3
Authority
PL
Poland
Prior art keywords
cancers
treatment
piperazinyl derivatives
piperazinyl
derivatives
Prior art date
Application number
PL12808851T
Other languages
English (en)
Inventor
Denis Carniato
Jean-François Briand
Mathieu Gutmann
Olivier Busnel
Cécile Bougeret
Benoit Deprez
Karine Jaillardon
Original Assignee
Pitty, Marc-Henry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pitty, Marc-Henry filed Critical Pitty, Marc-Henry
Publication of PL2797898T3 publication Critical patent/PL2797898T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12808851T 2011-12-30 2012-12-28 Pochodne piperazynylowe do leczenia nowotworów PL2797898T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1162586A FR2985256B1 (fr) 2011-12-30 2011-12-30 Derives piperazinyles pour le traitement de cancers

Publications (1)

Publication Number Publication Date
PL2797898T3 true PL2797898T3 (pl) 2017-03-31

Family

ID=47470025

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12808851T PL2797898T3 (pl) 2011-12-30 2012-12-28 Pochodne piperazynylowe do leczenia nowotworów

Country Status (17)

Country Link
US (1) US9321778B2 (pl)
EP (1) EP2797898B9 (pl)
JP (1) JP6105625B2 (pl)
KR (1) KR102086732B1 (pl)
CN (1) CN104053648B (pl)
AU (1) AU2012360815B2 (pl)
BR (1) BR112014015991B1 (pl)
CA (1) CA2859721C (pl)
ES (1) ES2606289T3 (pl)
FR (1) FR2985256B1 (pl)
HU (1) HUE030951T2 (pl)
IL (1) IL233414A (pl)
PL (1) PL2797898T3 (pl)
RU (1) RU2629115C2 (pl)
SG (1) SG11201403727YA (pl)
WO (1) WO2013098393A1 (pl)
ZA (1) ZA201405068B (pl)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10358539A1 (de) * 2003-12-15 2005-07-07 Merck Patent Gmbh Carbonsäureamidderivate
US20060058296A1 (en) * 2003-12-24 2006-03-16 Scios, Inc. Treatment of osteolytic lesions associated with multiple myeloma by inhibition of p38 map kinase
CN101010315A (zh) * 2004-04-30 2007-08-01 拜耳制药公司 用于治疗癌症的取代的吡唑基脲衍生物
US7615556B2 (en) * 2006-01-27 2009-11-10 Bristol-Myers Squibb Company Piperazinyl derivatives as modulators of chemokine receptor activity
US20100137398A1 (en) * 2007-05-04 2010-06-03 Novartis Ag Use of hdac inhibitors for the treatment of gastrointestinal cancers
FR2932483A1 (fr) * 2008-06-13 2009-12-18 Cytomics Systems Composes utiles pour le traitement des cancers.
WO2010091164A1 (en) * 2009-02-06 2010-08-12 Exelixis, Inc. Inhibitors of glucosylceramide synthase
CN102482233A (zh) * 2009-05-21 2012-05-30 阿斯利康(瑞典)有限公司 新颖的嘧啶衍生物和它们在治疗癌症和其它疾病中的用途
ES2704862T3 (es) * 2010-07-16 2019-03-20 Agios Pharmaceuticals Inc Composiciones terapéuticamente activas y su método de uso
WO2012129452A2 (en) 2011-03-22 2012-09-27 University Of Southern California Propynoic acid carbamoyl methyl-almides and pharmaceutical compositions and methods based thereon

Also Published As

Publication number Publication date
EP2797898A1 (fr) 2014-11-05
KR20140117456A (ko) 2014-10-07
US20140356360A1 (en) 2014-12-04
ES2606289T3 (es) 2017-03-23
EP2797898B9 (fr) 2021-05-26
EP2797898B1 (fr) 2016-09-14
RU2629115C2 (ru) 2017-08-24
JP6105625B2 (ja) 2017-03-29
CN104053648A (zh) 2014-09-17
CA2859721A1 (fr) 2013-07-04
HUE030951T2 (en) 2017-06-28
AU2012360815A1 (en) 2014-07-31
WO2013098393A1 (fr) 2013-07-04
HK1202118A1 (en) 2015-09-18
US9321778B2 (en) 2016-04-26
BR112014015991A2 (pt) 2017-06-13
FR2985256B1 (fr) 2016-03-04
BR112014015991B1 (pt) 2022-11-16
CA2859721C (fr) 2020-01-07
KR102086732B1 (ko) 2020-03-09
ZA201405068B (en) 2015-11-25
JP2015505308A (ja) 2015-02-19
BR112014015991A8 (pt) 2017-07-04
NZ627149A (en) 2015-08-28
FR2985256A1 (fr) 2013-07-05
SG11201403727YA (en) 2014-09-26
RU2014131001A (ru) 2016-02-20
CN104053648B (zh) 2016-09-28
AU2012360815B2 (en) 2017-02-02
IL233414A0 (en) 2014-08-31
IL233414A (en) 2015-11-30

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