PL2831077T3 - Bicykliczne pochodne pirazynonowe - Google Patents

Bicykliczne pochodne pirazynonowe

Info

Publication number: PL2831077T3
Authority: PL; Poland
Prior art keywords: pyrazinone derivatives; bicyclic; bicyclic pyrazinone; derivatives; pyrazinone
Prior art date: 2012-03-28

Application number

PL13712685.0T

Other languages

English (en)

Inventor

Dieter Dorsch

Hans-Peter Buchstaller

Gérard Moinet

Ansgar Wegener

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-03-28

Filing date

2013-03-19

Publication date

2016-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48013911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2831077(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-03-19 Application filed filed Critical

2016-10-31 Publication of PL2831077T3 publication Critical patent/PL2831077T3/pl

Links

-1 Bicyclic pyrazinone derivatives Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

PL13712685.0T 2012-03-28 2013-03-19 Bicykliczne pochodne pirazynonowe PL2831077T3 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP12002215		2012-03-28

Publications (1)

Publication Number	Publication Date
PL2831077T3 true PL2831077T3 (pl)	2016-10-31

Family

ID=48013911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL13712685.0T PL2831077T3 (pl)	2012-03-28	2013-03-19	Bicykliczne pochodne pirazynonowe

Country Status (31)

Country	Link
US (1)	US9120805B2 (pl)
EP (1)	EP2831077B1 (pl)
JP (1)	JP6096879B2 (pl)
KR (1)	KR102070567B1 (pl)
CN (1)	CN104169284B (pl)
AR (1)	AR090496A1 (pl)
AU (1)	AU2013242492B2 (pl)
CA (1)	CA2868620C (pl)
CL (1)	CL2014002557A1 (pl)
CO (1)	CO7111292A2 (pl)
DK (1)	DK2831077T3 (pl)
EA (1)	EA027416B1 (pl)
EC (1)	ECSP14024526A (pl)
ES (1)	ES2585044T3 (pl)
HR (1)	HRP20160908T1 (pl)
HU (1)	HUE030067T2 (pl)
IL (1)	IL234713A (pl)
MX (1)	MX351149B (pl)
MY (1)	MY172308A (pl)
NZ (1)	NZ630489A (pl)
PE (1)	PE20142186A1 (pl)
PH (1)	PH12014501829B1 (pl)
PL (1)	PL2831077T3 (pl)
PT (1)	PT2831077T (pl)
RS (1)	RS54997B1 (pl)
SG (1)	SG11201405750YA (pl)
SI (1)	SI2831077T1 (pl)
TW (1)	TWI576346B (pl)
UA (1)	UA112795C2 (pl)
WO (1)	WO2013143663A1 (pl)
ZA (1)	ZA201407828B (pl)

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EP2822656B1 (en)	2012-03-07	2016-10-19	Institute of Cancer Research: Royal Cancer Hospital (The)	3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
PL2831077T3 (pl)	2012-03-28	2016-10-31		Bicykliczne pochodne pirazynonowe
CN104395314A (zh) *	2012-06-20	2015-03-04	霍夫曼-拉罗奇有限公司	端锚聚合酶抑制剂吡咯并吡嗪酮
US9611223B2 (en)	2013-09-11	2017-04-04	Institute Of Cancer Research: Royal Cancer Hospital (The)	3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
CN105829317B (zh) *	2013-12-23	2019-03-29	默克专利股份公司	咪唑并吡嗪酮衍生物
WO2016006974A2 (en) *	2014-07-11	2016-01-14	St Pharm Co., Ltd.	Novel triazolopyrimidinone or triazolopyridinone derivatives, and use thereof
WO2016006975A2 (en) *	2014-07-11	2016-01-14	St Pharm Co., Ltd.	Novel imidazotriazinone or imidazopyrazinone derivatives, and use thereof
KR101739003B1 (ko) *	2014-07-11	2017-05-23	에스티팜 주식회사	신규한 트리아졸로피리미디논 또는 트리아졸로피리디논 유도체, 및 이들의 용도
KR20160007347A (ko)	2014-07-11	2016-01-20	에스티팜 주식회사	신규한 이미다조트리아지논 또는 이미다조피라지논 유도체, 및 이들의 용도
PL3227297T3 (pl)	2014-12-05	2021-10-25	Array Biopharma, Inc.	4,6 podstawione-pyrazolo[1,5-a]pirazyny jako inhibitory kinaz janusowych
MA42659A (fr)	2015-08-17	2018-06-27	Lupin Ltd	Dérivés hétéroaryle utilisés en tant qu'inhibiteurs de parp
RS60261B1 (sr)	2016-02-24	2020-06-30	Pfizer	Pirazolo[1,5-a]pirazin-4-il derivativi kao jak-inhibitori
WO2017156350A1 (en)	2016-03-09	2017-09-14	K-Gen, Inc.	Methods of cancer treatment
EP3668858A1 (en)	2017-08-14	2020-06-24	Pfizer Inc	Pyrazolo[1,5-a]pyrazin-4-yl and related derivatives
EP3793559A1 (en)	2018-05-17	2021-03-24	Bayer Aktiengesellschaft	Substituted dihydropyrazolo pyrazine carboxamide derivatives
GB2632307A (en) *	2023-08-02	2025-02-05	Duke Street Bio Ltd	PARP1 inhibitor compounds
GB2632441A (en) *	2023-08-08	2025-02-12	Duke Street Bio Ltd	Deuterated PARP1 inhibitor compounds
WO2025084446A1 (ko) *	2023-10-16	2025-04-24	에스티팜 주식회사	트리아졸로피리미디논 유도체의 결정형

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GB9624482D0 (en)	1995-12-18	1997-01-15	Zeneca Phaema S A	Chemical compounds
JP4471404B2 (ja)	1996-02-13	2010-06-02	アストラゼネカユーケイリミテッド	Ｖｅｇｆインヒビターとしてのキナゾリン誘導体
ATE211134T1 (de)	1996-03-05	2002-01-15		4-anilinochinazolin derivate
GB9718972D0 (en)	1996-09-25	1997-11-12	Zeneca Ltd	Chemical compounds
SE9702706D0 (sv)	1997-07-11	1997-07-11	Pharmacia & Upjohn Ab	Prostaglandin derivatives devoid of side-effects for the treatment of glaucoma
GB9900334D0 (en)	1999-01-07	1999-02-24	Angiogene Pharm Ltd	Tricylic vascular damaging agents
GB9900752D0 (en)	1999-01-15	1999-03-03	Angiogene Pharm Ltd	Benzimidazole vascular damaging agents
NZ522074A (en)	2000-05-31	2004-06-25	Astrazeneca Ab	Indole derivatives with vascular damaging activity
JP2004502766A (ja)	2000-07-07	2004-01-29	アンギオジェン・ファーマシューティカルズ・リミテッド	血管損傷剤としてのコルヒノール誘導体
CA2410562A1 (en)	2000-07-07	2002-01-31	Angiogene Pharmaceuticals Limited	Colchinol derivatives as angiogenesis inhibitors
CA2652167A1 (en) *	2006-05-31	2007-12-06	Philip Jones	Pyrrolo[1,2-a]pyrazin-1(2h)-one and pyrrolo[1,2-d][1,2,4]triazin-1(2h)-one derivatives as inhibitors of poly(adp-ribose)polymerase (parp)
ES2506090T3 (es) *	2006-12-28	2014-10-13	Abbvie Inc.	Inhibidores de la (ADP-ribosa) polimerasa
SI2134691T1 (sl)	2007-03-08	2012-06-29	Janssen Pharmaceutica Nv	Derivati kvinolina kot PARP in TANK inhibitorji
DE102007032349A1 (de)	2007-07-11	2009-01-15	Bayer Healthcare Ag	Imidazo-, Pyrazolopyrazine und Imidazotriazine und ihre Verwendung
WO2009130232A1 (en) *	2008-04-24	2009-10-29	Glaxo Group Limited	Pyrazolo [1, 5 -a] pyrazine derivatives as antagonists of v1b receptors
WO2009130231A1 (en)	2008-04-24	2009-10-29	Glaxo Group Limited	Pyrrolo [1, 2-a] pyrazine derivatives as vasopressin vib receptor antagonists
JP5579724B2 (ja)	2008-10-17	2014-08-27	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ホスファチジルイノシトール−３−キナーゼ（ｐｉ−３キナーゼ）阻害剤としてのテトラ−アザ−複素環
EP2526102B1 (en)	2010-01-22	2017-03-08	Fundación Centro Nacional de Investigaciones Oncológicas Carlos III	Inhibitors of PI3 kinase
CN102933584A (zh) *	2010-04-16	2013-02-13	Abbvie公司	激酶的吡咯并吡嗪酮抑制剂
CN102229611B (zh) *	2011-04-26	2012-12-12	山东大学	2,6-二芳基吡唑并[1,5-a]吡嗪-4(5H)-酮化合物及其应用
PL2831077T3 (pl)	2012-03-28	2016-10-31		Bicykliczne pochodne pirazynonowe
CN104395314A (zh) *	2012-06-20	2015-03-04	霍夫曼-拉罗奇有限公司	端锚聚合酶抑制剂吡咯并吡嗪酮

2013
- 2013-03-19 PL PL13712685.0T patent/PL2831077T3/pl unknown
- 2013-03-19 RS RS20160596A patent/RS54997B1/sr unknown
- 2013-03-19 ES ES13712685.0T patent/ES2585044T3/es active Active
- 2013-03-19 UA UAA201411566A patent/UA112795C2/uk unknown
- 2013-03-19 EA EA201401062A patent/EA027416B1/ru not_active IP Right Cessation
- 2013-03-19 MX MX2014011420A patent/MX351149B/es active IP Right Grant
- 2013-03-19 SI SI201330254A patent/SI2831077T1/sl unknown
- 2013-03-19 DK DK13712685.0T patent/DK2831077T3/en active
- 2013-03-19 JP JP2015502129A patent/JP6096879B2/ja active Active
- 2013-03-19 PE PE2014001502A patent/PE20142186A1/es active IP Right Grant
- 2013-03-19 HU HUE13712685A patent/HUE030067T2/en unknown
- 2013-03-19 AU AU2013242492A patent/AU2013242492B2/en active Active
- 2013-03-19 CA CA2868620A patent/CA2868620C/en active Active
- 2013-03-19 CN CN201380017205.4A patent/CN104169284B/zh active Active
- 2013-03-19 MY MYPI2014702730A patent/MY172308A/en unknown
- 2013-03-19 WO PCT/EP2013/000827 patent/WO2013143663A1/en not_active Ceased
- 2013-03-19 SG SG11201405750YA patent/SG11201405750YA/en unknown
- 2013-03-19 NZ NZ630489A patent/NZ630489A/en not_active IP Right Cessation
- 2013-03-19 US US14/388,270 patent/US9120805B2/en active Active
- 2013-03-19 EP EP13712685.0A patent/EP2831077B1/en active Active
- 2013-03-19 HR HRP20160908TT patent/HRP20160908T1/hr unknown
- 2013-03-19 KR KR1020147029895A patent/KR102070567B1/ko not_active Expired - Fee Related
- 2013-03-19 PT PT137126850T patent/PT2831077T/pt unknown
- 2013-03-26 AR ARP130100972A patent/AR090496A1/es active IP Right Grant
- 2013-03-27 TW TW102110996A patent/TWI576346B/zh not_active IP Right Cessation
2014
- 2014-08-13 PH PH12014501829A patent/PH12014501829B1/en unknown
- 2014-08-20 CO CO14182299A patent/CO7111292A2/es unknown
- 2014-09-18 IL IL234713A patent/IL234713A/en active IP Right Grant
- 2014-09-25 CL CL2014002557A patent/CL2014002557A1/es unknown
- 2014-10-27 EC ECIEPI201424526A patent/ECSP14024526A/es unknown
- 2014-10-27 ZA ZA2014/07828A patent/ZA201407828B/en unknown

Also Published As

Publication number	Publication date
EA027416B1 (ru)	2017-07-31
PH12014501829A1 (en)	2014-11-10
TW201343650A (zh)	2013-11-01
MX351149B (es)	2017-10-04
SI2831077T1 (sl)	2016-09-30
KR20140140099A (ko)	2014-12-08
AR090496A1 (es)	2014-11-19
CL2014002557A1 (es)	2014-12-19
AU2013242492A1 (en)	2014-11-13
TWI576346B (zh)	2017-04-01
CA2868620A1 (en)	2013-10-03
IL234713A (en)	2016-09-29
JP2015511609A (ja)	2015-04-20
DK2831077T3 (en)	2016-08-15
MY172308A (en)	2019-11-21
HK1203961A1 (en)	2015-11-06
CN104169284B (zh)	2017-03-29
EA201401062A1 (ru)	2015-04-30
UA112795C2 (uk)	2016-10-25
EP2831077B1 (en)	2016-04-27
ECSP14024526A (es)	2015-09-30
ZA201407828B (en)	2015-12-23
CO7111292A2 (es)	2014-11-10
HUE030067T2 (en)	2017-04-28
KR102070567B1 (ko)	2020-01-29
PH12014501829B1 (en)	2014-11-10
MX2014011420A (es)	2014-11-25
ES2585044T3 (es)	2016-10-03
NZ630489A (en)	2016-04-29
CA2868620C (en)	2020-02-25
HRP20160908T1 (hr)	2016-09-23
PE20142186A1 (es)	2014-12-29
CN104169284A (zh)	2014-11-26
EP2831077A1 (en)	2015-02-04
AU2013242492B2 (en)	2016-12-15
SG11201405750YA (en)	2014-10-30
RS54997B1 (sr)	2016-11-30
JP6096879B2 (ja)	2017-03-15
US20150057264A1 (en)	2015-02-26
WO2013143663A1 (en)	2013-10-03
US9120805B2 (en)	2015-09-01
PT2831077T (pt)	2016-08-12

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IL239109B (en)	2019-07-31	New quinolone derivatives
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IL236295A (en)	2016-09-29	The history of indanesulfamide
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ZA201405108B (en)	2015-10-28	Substituted phenylazole derivative
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GB201215033D0 (en)	2012-10-10	Diazepinone derivatives