PL2903624T3 - Pożywka kondycjonowana przez łożyskowe mezenchymalne komórki macierzyste z łożyska kobiety dotkniętej stanem przedrzucawkowym do stosowania w leczeniu nowotworu - Google Patents
Pożywka kondycjonowana przez łożyskowe mezenchymalne komórki macierzyste z łożyska kobiety dotkniętej stanem przedrzucawkowym do stosowania w leczeniu nowotworuInfo
- Publication number
- PL2903624T3 PL2903624T3 PL13792477T PL13792477T PL2903624T3 PL 2903624 T3 PL2903624 T3 PL 2903624T3 PL 13792477 T PL13792477 T PL 13792477T PL 13792477 T PL13792477 T PL 13792477T PL 2903624 T3 PL2903624 T3 PL 2903624T3
- Authority
- PL
- Poland
- Prior art keywords
- tumour
- treatment
- stem cell
- mesenchymal stem
- conditioned medium
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000003636 conditioned culture medium Substances 0.000 title 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 title 1
- 230000003169 placental effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2033—IL-5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2046—IL-7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2053—IL-8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/10—Protein-tyrosine kinases (2.7.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/27—Endoribonucleases producing 3'-phosphomonoesters (3.1.27)
- C12Y301/27008—Ribonuclease V (3.1.27.8)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000859A ITTO20120859A1 (it) | 2012-10-02 | 2012-10-02 | Nuova applicazione terapeutica di un mezzo condizionato da cellule staminali mesenchimali placentari |
| PCT/IB2013/059064 WO2014054004A1 (en) | 2012-10-02 | 2013-10-02 | Preeclamptic placental mesenchymal stem cell conditioned medium for use in the treatment of a tumour |
| EP13792477.5A EP2903624B1 (en) | 2012-10-02 | 2013-10-02 | Preeclamptic placental mesenchymal stem cell conditioned medium for use in the treatment of a tumour |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2903624T3 true PL2903624T3 (pl) | 2019-07-31 |
Family
ID=47278467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13792477T PL2903624T3 (pl) | 2012-10-02 | 2013-10-02 | Pożywka kondycjonowana przez łożyskowe mezenchymalne komórki macierzyste z łożyska kobiety dotkniętej stanem przedrzucawkowym do stosowania w leczeniu nowotworu |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9943548B2 (pl) |
| EP (1) | EP2903624B1 (pl) |
| JP (1) | JP6306025B2 (pl) |
| CN (2) | CN108939051B (pl) |
| CA (1) | CA2886946C (pl) |
| DK (1) | DK2903624T3 (pl) |
| ES (1) | ES2720232T3 (pl) |
| IT (1) | ITTO20120859A1 (pl) |
| PL (1) | PL2903624T3 (pl) |
| TR (1) | TR201905632T4 (pl) |
| WO (1) | WO2014054004A1 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170226472A1 (en) * | 2014-08-04 | 2017-08-10 | Universidad De Granada | Culture medium and method for enriching and maintaining cancer stem cells (cscs) using said medium |
| RU2644650C2 (ru) * | 2014-12-01 | 2018-02-13 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток и способ его получения |
| US11291689B2 (en) | 2015-06-03 | 2022-04-05 | Aelan Cell Technologies, Inc. | Methods and devices for the production and delivery of beneficial factors from adipose-derived stem cells |
| WO2016196774A1 (en) * | 2015-06-03 | 2016-12-08 | Aelan Cell Technologies, Inc. | Methods and devices for the production and delivery of beneficial factors from stem cells |
| RU2708329C2 (ru) * | 2016-05-31 | 2019-12-05 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток, композиции и способы применения |
| EP4600348A3 (en) * | 2016-08-26 | 2025-12-10 | Restem Llc | Composition and methods of using umbilical cord lining stem cells |
| JP2019214514A (ja) * | 2016-10-06 | 2019-12-19 | Aof株式会社 | 抗体産生力を上げる培養上清製剤 |
| US12053493B2 (en) | 2016-11-03 | 2024-08-06 | Exostem Biotec Ltd. | Mesenchymal stem cells populations, their products, and use thereof |
| KR101865040B1 (ko) * | 2017-01-05 | 2018-06-11 | 가톨릭대학교 산학협력단 | 면역조절인자의 생성능이 강화된 중간엽 줄기세포의 용도 |
| EP3823639A4 (en) * | 2018-07-18 | 2022-07-20 | Exostem Biotec Ltd. | IMMUNOTHERAPY BASED ON EXOSOMES AND MSC |
| US10881693B2 (en) | 2019-04-09 | 2021-01-05 | Combangio, Inc. | Processes for making and using a mesenchymal stem cell derived secretome |
| CN110025769A (zh) * | 2019-05-14 | 2019-07-19 | 美亚宜彬生物科技(北京)有限公司 | 干细胞和细胞因子的组合及其在改善精子活力的用途 |
| CN110904031A (zh) * | 2019-12-31 | 2020-03-24 | 福建省银丰干细胞工程有限公司 | 一种从人胎盘底蜕膜组织中分离母体来源间充质干细胞的方法 |
| WO2021207282A2 (en) | 2020-04-07 | 2021-10-14 | Combangio, Inc. | Lyophilized mesenchymal stem cell derived secretome and uses thereof |
| CN112315979A (zh) * | 2020-08-04 | 2021-02-05 | 源铭(上海)生物技术有限公司 | 药物组合物及其制备方法和应用 |
| CN114878837A (zh) * | 2022-05-31 | 2022-08-09 | 国家卫生健康委科学技术研究所 | 与妊娠期高血压疾病诊断相关的血清预测标志物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2530732C (en) * | 2003-06-27 | 2015-03-31 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| US20070087986A1 (en) * | 2004-01-26 | 2007-04-19 | Brett Premack | Compositions and methods for enhancing immunity by chemoattractant adjuvants |
| WO2006069449A1 (en) * | 2004-12-29 | 2006-07-06 | The University Of British Columbia | Chemokine receptor-independent immunomodulatory and anti-proliferative activity |
| US20060257359A1 (en) * | 2005-02-28 | 2006-11-16 | Cedric Francois | Modifying macrophage phenotype for treatment of disease |
| US7993918B2 (en) * | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| KR20110050688A (ko) * | 2008-08-22 | 2011-05-16 | 안트로제네시스 코포레이션 | 태반 세포 집단을 이용한 골 결함의 치료 방법 및 골 결함 치료 조성물 |
| ITTO20111183A1 (it) | 2011-12-21 | 2013-06-22 | Univ Degli Studi Torino | Mezzo condizionato ottenuto da cellule staminali mesenchimali placentari e suo uso nel trattamento terapeutico della preeclampsia |
-
2012
- 2012-10-02 IT IT000859A patent/ITTO20120859A1/it unknown
-
2013
- 2013-10-02 DK DK13792477.5T patent/DK2903624T3/en active
- 2013-10-02 PL PL13792477T patent/PL2903624T3/pl unknown
- 2013-10-02 CN CN201810895444.4A patent/CN108939051B/zh active Active
- 2013-10-02 TR TR2019/05632T patent/TR201905632T4/tr unknown
- 2013-10-02 US US14/432,722 patent/US9943548B2/en active Active
- 2013-10-02 EP EP13792477.5A patent/EP2903624B1/en active Active
- 2013-10-02 CN CN201380062876.2A patent/CN104822385B/zh active Active
- 2013-10-02 JP JP2015535152A patent/JP6306025B2/ja active Active
- 2013-10-02 WO PCT/IB2013/059064 patent/WO2014054004A1/en not_active Ceased
- 2013-10-02 CA CA2886946A patent/CA2886946C/en active Active
- 2013-10-02 ES ES13792477T patent/ES2720232T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2720232T3 (es) | 2019-07-18 |
| WO2014054004A9 (en) | 2015-06-11 |
| JP2015532099A (ja) | 2015-11-09 |
| JP6306025B2 (ja) | 2018-04-04 |
| DK2903624T3 (en) | 2019-04-29 |
| US9943548B2 (en) | 2018-04-17 |
| CA2886946C (en) | 2021-06-01 |
| EP2903624A1 (en) | 2015-08-12 |
| CN108939051A (zh) | 2018-12-07 |
| CA2886946A1 (en) | 2014-04-10 |
| EP2903624B1 (en) | 2019-01-16 |
| CN108939051B (zh) | 2022-04-15 |
| TR201905632T4 (tr) | 2019-05-21 |
| ITTO20120859A1 (it) | 2014-04-03 |
| CN104822385A (zh) | 2015-08-05 |
| WO2014054004A1 (en) | 2014-04-10 |
| CN104822385B (zh) | 2019-10-01 |
| US20150250823A1 (en) | 2015-09-10 |
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