PL2912039T3 - Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie - Google Patents

Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie

Info

Publication number
PL2912039T3
PL2912039T3 PL13824167T PL13824167T PL2912039T3 PL 2912039 T3 PL2912039 T3 PL 2912039T3 PL 13824167 T PL13824167 T PL 13824167T PL 13824167 T PL13824167 T PL 13824167T PL 2912039 T3 PL2912039 T3 PL 2912039T3
Authority
PL
Poland
Prior art keywords
camptothecin
derivatives
producing
Prior art date
Application number
PL13824167T
Other languages
English (en)
Inventor
Lech Kozerski
Robert Kawecki
Beata Naumczuk
Karolina Hyz
Wojciech Bocian
Jerzy Sitkowski
Elzbieta Bednarek
Katarzyna Wiktorska
Katarzyna Lubelska
Original Assignee
Inst Chemii Organicznej Polskiej Akademii Nauk
Narodowy Inst Lekow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Chemii Organicznej Polskiej Akademii Nauk, Narodowy Inst Lekow filed Critical Inst Chemii Organicznej Polskiej Akademii Nauk
Publication of PL2912039T3 publication Critical patent/PL2912039T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL13824167T 2012-10-25 2013-10-25 Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie PL2912039T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PL401345A PL235836B1 (pl) 2012-10-25 2012-10-25 Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie
EP13824167.4A EP2912039B1 (en) 2012-10-25 2013-10-25 Derivatives of camptothecin, a method of producing them and their use
PCT/IB2013/059668 WO2014064654A1 (en) 2012-10-25 2013-10-25 Derivatives of camptothecin, a method of producing them and their use

Publications (1)

Publication Number Publication Date
PL2912039T3 true PL2912039T3 (pl) 2018-01-31

Family

ID=50001041

Family Applications (2)

Application Number Title Priority Date Filing Date
PL401345A PL235836B1 (pl) 2012-10-25 2012-10-25 Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie
PL13824167T PL2912039T3 (pl) 2012-10-25 2013-10-25 Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL401345A PL235836B1 (pl) 2012-10-25 2012-10-25 Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie

Country Status (4)

Country Link
US (1) US9682992B2 (pl)
EP (1) EP2912039B1 (pl)
PL (2) PL235836B1 (pl)
WO (1) WO2014064654A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109206432A (zh) * 2017-06-30 2019-01-15 江苏汉邦科技有限公司 一种喜树碱单体的制备方法
LU102067B1 (en) 2020-09-17 2022-03-18 Narodowy Inst Lekow 7-Ethyl-10-hydroxycamptothecin derivatives for use in the treatment of cancer
WO2025255212A1 (en) * 2024-06-07 2025-12-11 Codeable Therapeutics, Incorporated Topoisomerase inhibitors, antibody-drug conjugates comprising them, and methods of their use
CN119912467B (zh) * 2025-01-22 2025-10-24 上海科技大学 一种氘代喜树碱衍生物及其制备方法与用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
JP2684104B2 (ja) * 1990-02-09 1997-12-03 株式会社ヤクルト本社 新規なカンプトテシン誘導体
ITMI20061474A1 (it) 2006-07-26 2008-01-27 Indena Spa Derivati della camptotecina ad attivita antitumorale
CN101133813B (zh) 2007-09-17 2010-06-09 国投中鲁果汁股份有限公司 一种浓缩黄瓜清汁及生产方法
ES2371171B1 (es) 2010-06-08 2012-11-16 Consejo Superior De Investigaciones Científicas (Csic) Derivados de camptotecina como agentes antitumorales.
CN103113381B (zh) * 2013-02-26 2014-12-10 大连理工大学 系列水溶性羟基喜树碱环烷胺醇衍生物及其制法与用途

Also Published As

Publication number Publication date
EP2912039B1 (en) 2017-07-12
US20150266888A1 (en) 2015-09-24
EP2912039A1 (en) 2015-09-02
PL235836B1 (pl) 2020-11-02
PL401345A1 (pl) 2014-04-28
WO2014064654A1 (en) 2014-05-01
US9682992B2 (en) 2017-06-20

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