PL2946782T3 - Preparaty farmaceutyczne zawierające siarczan chondroityny i pochodne kwasu hialuronowego - Google Patents
Preparaty farmaceutyczne zawierające siarczan chondroityny i pochodne kwasu hialuronowegoInfo
- Publication number
- PL2946782T3 PL2946782T3 PL15171519T PL15171519T PL2946782T3 PL 2946782 T3 PL2946782 T3 PL 2946782T3 PL 15171519 T PL15171519 T PL 15171519T PL 15171519 T PL15171519 T PL 15171519T PL 2946782 T3 PL2946782 T3 PL 2946782T3
- Authority
- PL
- Poland
- Prior art keywords
- hyaluronic acid
- acid derivatives
- pharmaceutical formulations
- chondroitin sulfate
- chondroitin
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 title 1
- 229920001287 Chondroitin sulfate Polymers 0.000 title 1
- 229940059329 chondroitin sulfate Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000098A ITPD20120098A1 (it) | 2012-03-30 | 2012-03-30 | "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico" |
| EP15171519.0A EP2946782B1 (en) | 2012-03-30 | 2013-03-27 | Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives |
| EP13722549.6A EP2830636A1 (en) | 2012-03-30 | 2013-03-27 | Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives |
| PCT/IB2013/052443 WO2013144867A1 (en) | 2012-03-30 | 2013-03-27 | Pharmaceutical formulations comprising chondroitin sulfate and hyaluronic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2946782T3 true PL2946782T3 (pl) | 2019-04-30 |
Family
ID=46000143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15171519T PL2946782T3 (pl) | 2012-03-30 | 2013-03-27 | Preparaty farmaceutyczne zawierające siarczan chondroityny i pochodne kwasu hialuronowego |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9655918B2 (pl) |
| EP (3) | EP2946782B1 (pl) |
| CN (1) | CN104220078A (pl) |
| CA (1) | CA2868078C (pl) |
| EA (2) | EA029237B1 (pl) |
| ES (2) | ES2709799T3 (pl) |
| HR (1) | HRP20190131T1 (pl) |
| IT (1) | ITPD20120098A1 (pl) |
| PL (1) | PL2946782T3 (pl) |
| SI (1) | SI2946782T1 (pl) |
| SM (1) | SMT201900061T1 (pl) |
| TR (1) | TR201901472T4 (pl) |
| WO (1) | WO2013144867A1 (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITPD20120098A1 (it) * | 2012-03-30 | 2013-10-01 | Fidia Farmaceutici | "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico" |
| ITMI20132116A1 (it) * | 2013-12-18 | 2015-06-19 | Apharm Srl | Associazione di glicosamminoglicani e ciclodestrine |
| CN104940221A (zh) * | 2015-05-13 | 2015-09-30 | 北京大清生物技术有限公司 | 一种用于膀胱和尿道上皮损伤修复的组合物 |
| EP3111941A1 (en) | 2015-06-30 | 2017-01-04 | Süleyman Patir | Compositions comprising chondroitin sulfate for prophylaxis or treatment of damaged articular cartilage |
| EP3400950B1 (de) * | 2017-05-12 | 2019-11-13 | Farco-Pharma GmbH | Blaseninstillationszusammensetzung enthaltend chondoitinsulfat (20 mg/ml), hyaluronsäure (16 mg/ml) und phosphatpuffer (ph 6,1 bis 7,9) mit erhöhter lagerstabiliät zur behandlung von cystitis |
| ES2775673T3 (es) * | 2017-05-12 | 2020-07-27 | Farco Gmbh | Composición para el tratamiento de enfermedades inflamatorias del tracto urogenital que contiene sulfato de condonita (4,5 mg/ml), ácido hialurónico (16 mg/ml) y tampón de fosfato (pH 6,1 a 7,9) con mayor estabilidad de almacenamiento para tratar la cistitis |
| US11766421B2 (en) | 2017-09-25 | 2023-09-26 | Surface Ophthalmics, Inc. | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
| KR20210141448A (ko) | 2018-12-27 | 2021-11-23 | 서피스 아프샐믹스 인코포레이티드 | 안구 표면 질환을 치료하기 위한 안과용 약학 조성물 및 방법 |
| KR102793214B1 (ko) | 2019-01-30 | 2025-04-08 | 보오슈 앤드 롬 인코포레이팃드 | 가교화 중합체 망상구조물 및 이의 용도 |
| IT201900024208A1 (it) * | 2019-12-17 | 2021-06-17 | Altergon Sa | Miscele iniettabili di acido ialuronico per uso in dermoestetica |
| TR201922945A2 (tr) * | 2019-12-31 | 2021-07-26 | Vsy Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi | Osteoartri̇t tedavi̇si̇ i̇çi̇n propoli̇s i̇çeri̇kli̇ yeni̇ bi̇r vi̇skoelasti̇k formülasyonu ve bunun üreti̇m yöntemi̇ |
| CN111333879B (zh) * | 2020-04-16 | 2022-08-16 | 山东众山生物科技有限公司 | 一种交联透明质酸的硫酸软骨素类化合物及其应用 |
| US20240269167A1 (en) * | 2020-12-21 | 2024-08-15 | Biointelligent Technology Systems Slu | A mucosal re-epithelialization composition |
| US12310981B2 (en) | 2021-05-10 | 2025-05-27 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
| US12440510B2 (en) | 2021-05-10 | 2025-10-14 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1212892B (it) | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
| FR2553099B1 (fr) | 1983-10-11 | 1989-09-08 | Fidia Spa | Fractions d'acide hyaluronique ayant une activite pharmaceutique, procedes pour leur preparation et compositions pharmaceutiques les contenant |
| US4713448A (en) | 1985-03-12 | 1987-12-15 | Biomatrix, Inc. | Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues |
| US6051560A (en) | 1986-06-26 | 2000-04-18 | Nestle S.A. | Chrondroitin sulfate/sodium hyaluronate composition |
| IT1219587B (it) | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| IT1263393B (it) | 1993-07-30 | 1996-08-05 | Fidia Advanced Biopolymers Srl | Processo per la preparazione e purificazione di acido ialuronico ad alto peso molecolare |
| ITPD940054A1 (it) | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | Polisaccaridi solfatati |
| IT1291291B1 (it) * | 1997-04-30 | 1999-01-07 | Chemedica Sa | Uso di acido ialuronico e relativi sali per la preparazione di una soluzione acquosa utile come liquido di lavaggio intra-articolare |
| US6872819B1 (en) * | 1998-05-27 | 2005-03-29 | Fidia Advanced Biopolymers S.R.L. | Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells |
| ITPD980169A1 (it) * | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
| DE10053053A1 (de) * | 2000-10-19 | 2002-05-16 | Knoell Hans Forschung Ev | Pharmazeutische Formulierungen zur Hemmung von entzündlichen Arthritiden |
| MXPA01011542A (es) * | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
| GB0130603D0 (en) * | 2001-12-20 | 2002-02-06 | Renaissance Healthcare Europ L | Improvements in or relating to ophthalmic solutions |
| US7504387B2 (en) * | 2002-10-16 | 2009-03-17 | Arthrodynamic Technologies, Animal Health Division, Inc. | Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis |
| WO2004034980A2 (en) * | 2002-10-16 | 2004-04-29 | Marcum Frank D | Treatment for traumatic synovitis and damaged articular cartilage |
| ITPD20050056A1 (it) * | 2005-03-02 | 2006-09-03 | Fidia Farmaceutici | Derivati ammidici del'acido ialuronico in osteoartrosi |
| ITMI20061030A1 (it) * | 2006-05-26 | 2007-11-27 | Altergon Sa | Nuova composizione comprendente glicosamminoglicani a viscosita' controllata e uso di tale composizione nella terapuia della cistite cronica |
| ITPD20060219A1 (it) * | 2006-05-31 | 2007-12-01 | Fidia Farmaceutici | Composizioni farmaceutiche contenenti acido ialuronico solfatato nel trattamento dell'osteoartrosi |
| CN100594029C (zh) * | 2006-07-24 | 2010-03-17 | 凌沛学 | 一种关节腔内注射用药物组合物 |
| US8343942B2 (en) * | 2008-04-04 | 2013-01-01 | University Of Utah Research Foundation | Methods for treating interstitial cystitis |
| IT1393945B1 (it) * | 2009-04-21 | 2012-05-17 | Fidia Farmaceutici | Composizioni comprendenti acido ialuronico, acido ialuronico solfatato, calcio e vitamina d3 nel trattamento delle malattie osteoarticolari e muscoloscheletriche |
| IT1395392B1 (it) | 2009-08-27 | 2012-09-14 | Fidia Farmaceutici | Geli viscoelastici come nuovi filler |
| FR2954165B1 (fr) * | 2009-12-18 | 2012-01-13 | Jean-Noel Thorel | Compositions injectables a usage intra-articulaire associant un agent de viscosupplementation et un milieu de croissance des fibroblastes |
| ITPD20120098A1 (it) * | 2012-03-30 | 2013-10-01 | Fidia Farmaceutici | "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico" |
-
2012
- 2012-03-30 IT IT000098A patent/ITPD20120098A1/it unknown
-
2013
- 2013-03-27 TR TR2019/01472T patent/TR201901472T4/tr unknown
- 2013-03-27 SI SI201331339T patent/SI2946782T1/sl unknown
- 2013-03-27 US US14/389,301 patent/US9655918B2/en active Active
- 2013-03-27 CN CN201380018447.5A patent/CN104220078A/zh active Pending
- 2013-03-27 WO PCT/IB2013/052443 patent/WO2013144867A1/en not_active Ceased
- 2013-03-27 SM SM20190061T patent/SMT201900061T1/it unknown
- 2013-03-27 ES ES15171519T patent/ES2709799T3/es active Active
- 2013-03-27 ES ES18200663T patent/ES2887581T3/es active Active
- 2013-03-27 EA EA201401074A patent/EA029237B1/ru not_active IP Right Cessation
- 2013-03-27 EA EA201792023A patent/EA201792023A3/ru unknown
- 2013-03-27 EP EP15171519.0A patent/EP2946782B1/en active Active
- 2013-03-27 EP EP13722549.6A patent/EP2830636A1/en not_active Withdrawn
- 2013-03-27 EP EP18200663.5A patent/EP3449927B1/en active Active
- 2013-03-27 PL PL15171519T patent/PL2946782T3/pl unknown
- 2013-03-27 CA CA2868078A patent/CA2868078C/en active Active
-
2017
- 2017-04-17 US US15/489,299 patent/US10821131B2/en active Active
-
2019
- 2019-01-21 HR HRP20190131TT patent/HRP20190131T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201401074A1 (ru) | 2015-01-30 |
| EA029237B1 (ru) | 2018-02-28 |
| CA2868078C (en) | 2020-04-14 |
| EP2946782A2 (en) | 2015-11-25 |
| CA2868078A1 (en) | 2013-10-03 |
| US20150072954A1 (en) | 2015-03-12 |
| EA201792023A2 (ru) | 2018-01-31 |
| ES2709799T3 (es) | 2019-04-17 |
| ES2887581T3 (es) | 2021-12-23 |
| EP3449927B1 (en) | 2021-06-23 |
| EP2946782A3 (en) | 2016-02-24 |
| EA201792023A3 (ru) | 2018-04-30 |
| CN104220078A (zh) | 2014-12-17 |
| TR201901472T4 (tr) | 2019-02-21 |
| WO2013144867A1 (en) | 2013-10-03 |
| US10821131B2 (en) | 2020-11-03 |
| US20170216344A1 (en) | 2017-08-03 |
| SMT201900061T1 (it) | 2019-02-28 |
| EP2830636A1 (en) | 2015-02-04 |
| SI2946782T1 (sl) | 2019-03-29 |
| HRP20190131T1 (hr) | 2019-03-22 |
| EP3449927A1 (en) | 2019-03-06 |
| EP2946782B1 (en) | 2018-11-07 |
| ITPD20120098A1 (it) | 2013-10-01 |
| US9655918B2 (en) | 2017-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20190131T1 (hr) | Farmaceutske formulacije koje sadrže hondroitin-sulfat i derivate hijaluronske kiseline | |
| IL233756A (en) | History of hydroxamic acid and their pharmaceutical preparations | |
| IL236024A (en) | The history of benzimidazole-proline and its pharmaceutical preparations | |
| ZA201406233B (en) | Pharmaceutical composition and administration thereof | |
| IL252566B (en) | Pharmacy preparations and methods | |
| PL2842945T3 (pl) | Pochodna sulfonamidowa i jej zastosowanie medyczne | |
| IL236057B (en) | History of 4,2,1-triazine-6-carboxamide and pharmaceutical preparations containing them | |
| IL228408A0 (en) | History as Falosporin and their medicinal preparations | |
| IL250370A0 (en) | Propionic acid derivatives substituted with heteroaroylamino in position 3 and their use as pharmaceuticals | |
| ZA201409020B (en) | Pharmaceutical formulation | |
| IL249826A0 (en) | Propionic acid derivatives converted in 3-heteroylamino and their use in pharmaceutical preparations | |
| ZA201503171B (en) | Modified hyaluronic acid derivatives and use thereof | |
| IL221087A (en) | Pharmacy or nutritional composition | |
| EP2832724A4 (en) | NIPETIC ACID DERIVATIVE AND ITS USE FOR MEDICAL PURPOSES | |
| SG11201406942SA (en) | Trans-2-decenoic acid derivative and drug containing same | |
| PL2854789T3 (pl) | Formulacje leków oparte na genotypie lub fenotypie | |
| GB201208315D0 (en) | Pharmaceutical methods and compositions | |
| IL240447A (en) | Propionic Acid-Baryl Acid Derivatives and Their Use as Pharmaceutical Preparations | |
| GB201211403D0 (en) | Pharmaceutical formulations | |
| GB201211406D0 (en) | Pharmaceutical formulations | |
| IL240422A0 (en) | Bi-aryl derivatives of propionic acid and their use as medicinal preparations | |
| GB201112578D0 (en) | Pharmaceutical preparation and use |