PL2978419T3 - Kompozycje do zwiększania żywotności komórek i metody ich stosowania - Google Patents

Kompozycje do zwiększania żywotności komórek i metody ich stosowania

Info

Publication number
PL2978419T3
PL2978419T3 PL14775675T PL14775675T PL2978419T3 PL 2978419 T3 PL2978419 T3 PL 2978419T3 PL 14775675 T PL14775675 T PL 14775675T PL 14775675 T PL14775675 T PL 14775675T PL 2978419 T3 PL2978419 T3 PL 2978419T3
Authority
PL
Poland
Prior art keywords
compositions
methods
cell viability
improving cell
improving
Prior art date
Application number
PL14775675T
Other languages
English (en)
Inventor
Joshua B. Cohen
Justin Klee
Original Assignee
Amylyx Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51569584&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2978419(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amylyx Pharmaceuticals Inc. filed Critical Amylyx Pharmaceuticals Inc.
Publication of PL2978419T3 publication Critical patent/PL2978419T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL14775675T 2013-03-24 2014-02-24 Kompozycje do zwiększania żywotności komórek i metody ich stosowania PL2978419T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361804690P 2013-03-24 2013-03-24
US14/140,083 US9872865B2 (en) 2013-03-24 2013-12-24 Compositions for improving cell viability and methods of use thereof
PCT/US2014/018040 WO2014158547A1 (en) 2013-03-24 2014-02-24 Compositions for improving cell viability and methods of use thereof
EP14775675.3A EP2978419B1 (en) 2013-03-24 2014-02-24 Compositions for improving cell viability and methods of use thereof

Publications (1)

Publication Number Publication Date
PL2978419T3 true PL2978419T3 (pl) 2020-10-19

Family

ID=51569584

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14775675T PL2978419T3 (pl) 2013-03-24 2014-02-24 Kompozycje do zwiększania żywotności komórek i metody ich stosowania

Country Status (20)

Country Link
US (8) US9872865B2 (pl)
EP (3) EP2978419B1 (pl)
JP (6) JP6495237B2 (pl)
KR (6) KR102396714B1 (pl)
CN (3) CN105050593B (pl)
AU (5) AU2014242123B2 (pl)
CA (1) CA2908683A1 (pl)
CY (1) CY1123092T1 (pl)
DK (1) DK2978419T3 (pl)
ES (1) ES2796250T3 (pl)
HR (1) HRP20200990T1 (pl)
HU (1) HUE051105T2 (pl)
LT (1) LT2978419T (pl)
ME (1) ME03747B (pl)
PL (1) PL2978419T3 (pl)
PT (1) PT2978419T (pl)
RS (1) RS60596B1 (pl)
SI (1) SI2978419T1 (pl)
SM (1) SMT202000326T1 (pl)
WO (1) WO2014158547A1 (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9872865B2 (en) 2013-03-24 2018-01-23 Amylyx Pharmaceuticals Inc. Compositions for improving cell viability and methods of use thereof
MX389242B (es) * 2015-06-15 2025-03-20 Nmd Pharma As Compuestos para su uso en el tratamiento de trastornos neuromusculares
KR101743960B1 (ko) * 2015-07-06 2017-06-08 서울대학교산학협력단 G단백질 결합형 수용체19 작용제를 유효성분으로 함유하는 알츠하이머 질환 또는 치매를 예방, 치료 또는 지연하기 위한 약학적 조성물
AU2016321298A1 (en) * 2015-09-09 2018-03-29 The Trustees Of Columbia University In The City Of New York Reduction of ER-MAM localized APP-C99 and methods of treating Alzheimer's Disease
CN110177572A (zh) * 2016-09-12 2019-08-27 史蒂文·霍夫曼 用于治疗痴呆的组合物
WO2018157014A1 (en) * 2017-02-24 2018-08-30 Duke University Metabolic biomarkers for the identification and characterization of alzheimer's disease
US11147788B2 (en) 2017-12-14 2021-10-19 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11591284B2 (en) 2017-12-14 2023-02-28 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11730714B2 (en) 2017-12-14 2023-08-22 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US12440477B2 (en) 2017-12-14 2025-10-14 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
JP7474706B2 (ja) * 2018-12-18 2024-04-25 参天製薬株式会社 ４－フェニル酪酸を含有する老視の治療または予防剤
WO2020232227A1 (en) 2019-05-14 2020-11-19 Tyme, Inc. Compositions and methods for treating cancer
US11583542B2 (en) 2019-12-16 2023-02-21 Amylyx Pharmaceuticals, Inc. Compositions of bile acids and phenylbutyrate compounds
IL293907A (en) * 2019-12-16 2022-08-01 Amylyx Pharmaceuticals Inc Treatment of amyotrophic lateral sclerosis and related disorders
JP7701931B2 (ja) * 2020-02-13 2025-07-02 プリレニア ニューロセラピューティクス リミテッド プリドピジンおよび他の活性薬剤を使用して筋萎縮性側索を治療するための併用療法
US10905698B1 (en) 2020-05-14 2021-02-02 Tyme, Inc. Methods of treating SARS-COV-2 infections
WO2022188029A1 (zh) * 2021-03-09 2022-09-15 兆科药业（广州）有限公司 一种含牛磺熊去氧胆酸、苯丁酸钠的复方散剂/颗粒剂、制备方法、用途以及其药物组合物
WO2022191296A1 (ja) * 2021-03-10 2022-09-15 昭和電工マテリアルズ株式会社 培地組成物、細胞培養物の製造方法、及び細胞懸濁物
CN113332267A (zh) * 2021-03-31 2021-09-03 中山大学孙逸仙纪念医院 苯丁酸钠在制备预防或治疗帕金森病的药物中的应用
CN113349300A (zh) * 2021-06-07 2021-09-07 湖南农业大学 4-苯基丁酸在制备猪肠道保健产品中的应用
KR20240119072A (ko) * 2021-11-08 2024-08-06 아밀릭스 파마슈티컬스 인코포레이티드 신경퇴행성 질환의 치료를 위한 담즙산과 페닐 부티레이트 화합물의 병용
CN116159068A (zh) * 2021-11-25 2023-05-26 香港理工大学深圳研究院 胆汁酸和/或胆汁酸受体激动剂的新应用
IL313090A (en) * 2021-12-02 2024-07-01 Marvelbiome Inc Methods and uses of microbiome compositions, components or metabolites for the treatment of diseases, disorders and conditions related to the vagus nerve
US20230277630A1 (en) 2022-03-02 2023-09-07 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
US12138272B2 (en) * 2022-05-12 2024-11-12 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
US20230372263A1 (en) 2022-05-17 2023-11-23 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
WO2024015281A1 (en) * 2022-07-11 2024-01-18 AI Therapeutics, Inc. Apilimod combination therapy
WO2024015286A1 (en) * 2022-07-11 2024-01-18 AI Therapeutics, Inc. Apilimod combination therapy
US20240100069A1 (en) 2022-09-07 2024-03-28 Amylyx Pharmaceuticals, Inc. Methods and Compositions for Treating Amyotrophic Lateral Sclerosis
WO2024072778A1 (en) 2022-09-29 2024-04-04 Amylyx Pharmaceuticals, Inc. Methods and compositions for treating amyotrophic lateral sclerosis
TW202440100A (zh) 2022-10-31 2024-10-16 瑞士商諾華公司 用於治療由csf-1r調節的疾病的給藥方案
WO2024105168A1 (en) * 2022-11-18 2024-05-23 Inflectis Bioscience Novel combinations useful for the treatments of als
EP4649317A2 (en) * 2023-01-12 2025-11-19 Population Bio, Inc. Methods and compositions for screening and treating alzheimer's disease
WO2025054193A2 (en) * 2023-09-05 2025-03-13 Amylyx Pharmaceuticals, Inc. Compositions and methods for treating subjects with renal impairment
CN121197183B (zh) * 2025-12-01 2026-04-14 中国农业科学院饲料研究所 3-oxoLCA在降低妊娠母体及其子代的氧化应激和炎症中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225031A1 (en) 2002-05-21 2003-12-04 Quay Steven C. Administration of acetylcholinesterase inhibitors to the cerebral spinal fluid
CN1770975A (zh) 2003-04-02 2006-05-10 明尼苏达大学评议会 提高细胞生存能力的方法
JP2008518935A (ja) * 2004-11-01 2008-06-05 セオ ホン ユー 筋萎縮性側索硬化症の神経退行を減少させるための方法及び組成物
ES2358089T3 (es) 2004-11-01 2011-05-05 Seo Hong Yoo Métodos y composiciones para reducir la neurodegeneración en esclerosis lateral amiotrófica.
US20060135612A1 (en) 2004-12-17 2006-06-22 U.S. Department Of Veterans Affairs Method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), by using a HDAC inhibiting agent
JP2008530100A (ja) 2005-02-10 2008-08-07 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 視覚障害の治療方法
CN101534641A (zh) 2006-03-22 2009-09-16 哈佛大学校长及研究员协会 治疗高胆固醇血症和动脉粥样硬化的方法和组合物
US7737175B2 (en) 2007-06-01 2010-06-15 Duke University Methods and compositions for regulating HDAC4 activity
CA2649740A1 (en) * 2008-01-14 2009-07-14 Queen's University At Kingston Therapies for cognition and learning enhancement
ES2332687B1 (es) 2008-03-13 2011-01-10 Proyecto De Biomedicina Cima, S.L. Nuevos usos de 4pba y sus sales farmaceuticamente aceptables.
AU2009246539B2 (en) 2008-05-12 2014-12-04 Children's Medical Center Corporation Methods and compositions for the treatment of obesity
WO2010008860A1 (en) 2008-06-23 2010-01-21 President And Fellows Of Harvard College Modulation of neurodegenerative disease by modulating xbp-1 activity
US20120157419A1 (en) 2009-02-02 2012-06-21 Tuvia Gilat Methods and compositions for treating alzheimer's disease
EP2422787A1 (en) 2010-08-17 2012-02-29 Neurotec Pharma, S.L. Diazoxide for use in the treatment of amyotrophic lateral sclerosis (als)
WO2013067096A2 (en) 2011-11-01 2013-05-10 Metselex, Inc. Prevention or attenuation of neuropathic pain and kidney injury by tauroursodeoxycholic acid
EP2599477A1 (en) 2011-11-30 2013-06-05 Lunamed AG 4-Phenylbutyric acid sustained release formulation
WO2013142490A2 (en) 2012-03-20 2013-09-26 Metselex, Inc. Tauroursodeoxycholic acid attenuates or abolishes formation and deposition of amyloid-b peptide
US9872865B2 (en) 2013-03-24 2018-01-23 Amylyx Pharmaceuticals Inc. Compositions for improving cell viability and methods of use thereof
HRP20181554T4 (hr) 2013-07-01 2026-03-27 Bruschettini S.R.L. Tauroursodezoksikolna kiselina (tudca), namijenjena upotrebi u liječenju neurodegenerativnih poremećaja
US10142799B2 (en) 2014-08-19 2018-11-27 Qualcomm Incorporated Multicasting traffic using multi-connectivity

Also Published As

Publication number Publication date
AU2022221410B2 (en) 2024-12-12
CN110787169B (zh) 2023-10-20
AU2014242123A1 (en) 2015-09-17
US20190255072A1 (en) 2019-08-22
AU2014242123B2 (en) 2018-11-01
CA2908683A1 (en) 2014-10-02
US20180098999A1 (en) 2018-04-12
LT2978419T (lt) 2020-08-10
HK1216851A1 (zh) 2016-12-09
JP7242945B2 (ja) 2023-03-20
JP6495237B2 (ja) 2019-04-03
KR20220066178A (ko) 2022-05-23
ES2796250T3 (es) 2020-11-26
KR20150135471A (ko) 2015-12-02
US9872865B2 (en) 2018-01-23
DK2978419T3 (da) 2020-05-04
JP2021008473A (ja) 2021-01-28
SI2978419T1 (sl) 2020-11-30
WO2014158547A1 (en) 2014-10-02
US10857162B2 (en) 2020-12-08
EP4509120A3 (en) 2025-04-23
JP2019123721A (ja) 2019-07-25
CY1123092T1 (el) 2021-10-29
US11071742B2 (en) 2021-07-27
EP2978419A1 (en) 2016-02-03
CN105050593A (zh) 2015-11-11
JP7080944B2 (ja) 2022-06-06
JP2022122929A (ja) 2022-08-23
AU2019200658B2 (en) 2020-12-24
AU2025201758A1 (en) 2025-04-03
EP2978419A4 (en) 2016-11-16
US12186330B2 (en) 2025-01-07
KR102460746B1 (ko) 2022-10-31
US20220160733A1 (en) 2022-05-26
RS60596B1 (sr) 2020-08-31
EP3750531B1 (en) 2024-09-18
HUE051105T2 (hu) 2021-03-01
AU2022221410A1 (en) 2022-09-15
CN109999043B (zh) 2023-01-20
US20220110948A1 (en) 2022-04-14
KR20230164242A (ko) 2023-12-01
JP6766198B2 (ja) 2020-10-07
US20250275985A1 (en) 2025-09-04
ME03747B (me) 2021-04-20
KR102607635B1 (ko) 2023-11-30
KR102804813B1 (ko) 2025-05-12
KR102396714B1 (ko) 2022-05-12
KR20220148337A (ko) 2022-11-04
US20200230156A1 (en) 2020-07-23
HRP20200990T1 (hr) 2020-10-16
EP3750531A1 (en) 2020-12-16
CN105050593B (zh) 2019-12-03
JP7806187B2 (ja) 2026-01-26
EP4509120A2 (en) 2025-02-19
JP2025041628A (ja) 2025-03-26
KR20210025134A (ko) 2021-03-08
KR102223250B1 (ko) 2021-03-08
JP2023085274A (ja) 2023-06-20
AU2019200658A1 (en) 2019-02-21
US20140288030A1 (en) 2014-09-25
US10251896B2 (en) 2019-04-09
JP2016515575A (ja) 2016-05-30
US20200171052A1 (en) 2020-06-04
AU2021201770B2 (en) 2022-05-26
PT2978419T (pt) 2020-06-19
JP7596421B2 (ja) 2024-12-09
CN109999043A (zh) 2019-07-12
KR20210156312A (ko) 2021-12-24
EP2978419B1 (en) 2020-04-15
CN110787169A (zh) 2020-02-14
SMT202000326T1 (it) 2020-07-08
AU2021201770A1 (en) 2021-04-15

Similar Documents

Publication Publication Date Title
SMT202000326T1 (it) Composizioni per migliorare la vitalità cellulare e loro metodi di uso
EP2971014A4 (en) CELL CULTURE METHODS
EP2971040A4 (en) CELL CULTURE METHODS
IL242701B (en) Preparations of irna 6tmprss and methods of using them
IL237527A0 (en) Devices and methods for growing cells
SMT201900635T1 (it) Composizioni e metodi di attivazione della segnalazione dipendente dallo "stimolatore di geni interferone"
IL244296A0 (en) Cell-permeable conjugates and methods of using them
ZA201408594B (en) Xylitol-based anti-mucosal compositions and related methods and compositions
GB201308072D0 (en) Compositions and methods
GB201200458D0 (en) Methods of preparing cells and compositions
EP2968244A4 (en) COMPOSITIONS AND METHODS FOR USING ALIGAL COMPOUNDS
ZA201406726B (en) Methods and composition related to brown adipose-like cells
IL239631A0 (en) Anti-integrin cell 1 antibody preparations and methods of using them
SG11201504771RA (en) Host cells and methods of use
GB201305813D0 (en) Compositions and methods
IL245123A0 (en) Short interfering RNA and its use in methods and preparations for preventing the expression of the orai1 gene
IL245272A0 (en) pif-transfected cells and methods of use
SG11201509437XA (en) Methods and compositions for enhancing stem cell mobilization
GB201315350D0 (en) Methods and compositions
GB201315347D0 (en) Methods and compositions
IL233961B (en) The composition of a phytogenic supplement and methods of its use
EP2892522A4 (en) HMB AND ATP COMPOSITION AND METHODS OF USE
EP2885001A4 (en) NEW CELL COMPOSITIONS AND METHODS
EP2859071A4 (en) CHEMICAL COMPOSITIONS AND METHODS OF USE
GB201307377D0 (en) Devices and methods for culture of cells