PL2978847T3 - Rybozymy typu hammerhead skierowane przeciw mir-21 - Google Patents
Rybozymy typu hammerhead skierowane przeciw mir-21Info
- Publication number
- PL2978847T3 PL2978847T3 PL14719866T PL14719866T PL2978847T3 PL 2978847 T3 PL2978847 T3 PL 2978847T3 PL 14719866 T PL14719866 T PL 14719866T PL 14719866 T PL14719866 T PL 14719866T PL 2978847 T3 PL2978847 T3 PL 2978847T3
- Authority
- PL
- Poland
- Prior art keywords
- hammerhead ribozymes
- targeting mir
- ribozymes targeting
- mir
- hammerhead
- Prior art date
Links
- 102000053642 Catalytic RNA Human genes 0.000 title 1
- 108090000994 Catalytic RNA Proteins 0.000 title 1
- 241000251131 Sphyrna Species 0.000 title 1
- 108091062762 miR-21 stem-loop Proteins 0.000 title 1
- 108091041631 miR-21-1 stem-loop Proteins 0.000 title 1
- 108091044442 miR-21-2 stem-loop Proteins 0.000 title 1
- 108091092562 ribozyme Proteins 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL403341A PL228060B1 (pl) | 2013-03-27 | 2013-03-27 | Rybozymy typu „hammerhead”, kompozycja, srodek terapeutyczny je obejmujace, ich zastosowania oraz sposób selektywnej hydrolizy ex -vivo miR21 i prekursorów miR21 |
| EP14719866.7A EP2978847B1 (en) | 2013-03-27 | 2014-03-26 | Hammerhead ribozymes targeting mir-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2978847T3 true PL2978847T3 (pl) | 2017-08-31 |
Family
ID=50588767
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL403341A PL228060B1 (pl) | 2013-03-27 | 2013-03-27 | Rybozymy typu „hammerhead”, kompozycja, srodek terapeutyczny je obejmujace, ich zastosowania oraz sposób selektywnej hydrolizy ex -vivo miR21 i prekursorów miR21 |
| PL14719866T PL2978847T3 (pl) | 2013-03-27 | 2014-03-26 | Rybozymy typu hammerhead skierowane przeciw mir-21 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL403341A PL228060B1 (pl) | 2013-03-27 | 2013-03-27 | Rybozymy typu „hammerhead”, kompozycja, srodek terapeutyczny je obejmujace, ich zastosowania oraz sposób selektywnej hydrolizy ex -vivo miR21 i prekursorów miR21 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160046938A1 (pl) |
| EP (1) | EP2978847B1 (pl) |
| PL (2) | PL228060B1 (pl) |
| WO (1) | WO2014155320A1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10301626B2 (en) | 2015-03-02 | 2019-05-28 | The Regents Of The University Of California | Catalytic strands of minimal hammerhead ribozymes and methods of using the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7034009B2 (en) * | 1995-10-26 | 2006-04-25 | Sirna Therapeutics, Inc. | Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R) |
-
2013
- 2013-03-27 PL PL403341A patent/PL228060B1/pl unknown
-
2014
- 2014-03-26 US US14/780,001 patent/US20160046938A1/en not_active Abandoned
- 2014-03-26 EP EP14719866.7A patent/EP2978847B1/en not_active Not-in-force
- 2014-03-26 WO PCT/IB2014/060188 patent/WO2014155320A1/en not_active Ceased
- 2014-03-26 PL PL14719866T patent/PL2978847T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160046938A1 (en) | 2016-02-18 |
| EP2978847A1 (en) | 2016-02-03 |
| WO2014155320A1 (en) | 2014-10-02 |
| PL228060B1 (pl) | 2018-02-28 |
| PL403341A1 (pl) | 2014-09-29 |
| EP2978847B1 (en) | 2017-02-15 |
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