PL2986325T3 - Sposoby leczenia zaburzenia cyklu mocznikowego - Google Patents

Sposoby leczenia zaburzenia cyklu mocznikowego

Info

Publication number
PL2986325T3
PL2986325T3 PL14854074T PL14854074T PL2986325T3 PL 2986325 T3 PL2986325 T3 PL 2986325T3 PL 14854074 T PL14854074 T PL 14854074T PL 14854074 T PL14854074 T PL 14854074T PL 2986325 T3 PL2986325 T3 PL 2986325T3
Authority
PL
Poland
Prior art keywords
methods
urea cycle
cycle disorder
treating urea
treating
Prior art date
Application number
PL14854074T
Other languages
English (en)
Inventor
Masoud MOKHTARANI
Bruce Scharschmidt
Original Assignee
Immedica Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immedica Pharma Ab filed Critical Immedica Pharma Ab
Publication of PL2986325T3 publication Critical patent/PL2986325T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7057(Intracellular) signaling and trafficking pathways
    • G01N2800/7066Metabolic pathways
    • G01N2800/708Nitrogen metabolism, e.g. urea cycle

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
PL14854074T 2013-10-14 2014-10-14 Sposoby leczenia zaburzenia cyklu mocznikowego PL2986325T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361890827P 2013-10-14 2013-10-14
US201462044168P 2014-08-29 2014-08-29
PCT/US2014/060543 WO2015057747A1 (en) 2013-10-14 2014-10-14 Methods of treating urea cycle disorders
EP14854074.3A EP2986325B1 (en) 2013-10-14 2014-10-14 Methods of treating urea cycle disorders

Publications (1)

Publication Number Publication Date
PL2986325T3 true PL2986325T3 (pl) 2020-03-31

Family

ID=52810198

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14854074T PL2986325T3 (pl) 2013-10-14 2014-10-14 Sposoby leczenia zaburzenia cyklu mocznikowego

Country Status (14)

Country Link
US (7) US20150105469A1 (pl)
EP (1) EP2986325B1 (pl)
CY (1) CY1122220T1 (pl)
DK (1) DK2986325T3 (pl)
ES (1) ES2746999T3 (pl)
HR (1) HRP20191710T1 (pl)
HU (1) HUE045106T2 (pl)
LT (1) LT2986325T (pl)
PL (1) PL2986325T3 (pl)
PT (1) PT2986325T (pl)
RS (1) RS59429B1 (pl)
SI (1) SI2986325T1 (pl)
SM (1) SMT201900542T1 (pl)
WO (1) WO2015057747A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2760479T (lt) 2011-09-30 2017-07-10 Horizon Therapeutics, Llc Azotą pašalinantis vaistas, skirtas naudoti azoto užlaikymo sutrikimo gydymo būde
AU2013347905B2 (en) 2012-11-21 2018-10-04 Immedica Pharma Ab Methods of administering and evaluating nitrogen scavenging drugs for the treatment of hepatic encephalopathy
WO2017147193A1 (en) * 2016-02-22 2017-08-31 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4858796A (en) 1995-02-07 1996-08-27 Saul W. Brusilow Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in treatment of various disorders
PL3133396T3 (pl) 2008-04-29 2019-03-29 Horizon Therapeutics, Llc Sposób leczenia z zastosowaniem leków wychwytujących amoniak
CA2735234A1 (en) * 2008-08-29 2010-03-04 Ucyclyd Pharma, Inc. Dosing and monitoring patients on nitrogen-scavenging drugs
WO2011011781A1 (en) 2009-07-24 2011-01-27 Baylor College Of Medicine Methods of modulation of branched chain acids and uses thereof
LT2760479T (lt) 2011-09-30 2017-07-10 Horizon Therapeutics, Llc Azotą pašalinantis vaistas, skirtas naudoti azoto užlaikymo sutrikimo gydymo būde
BR112014026138A2 (pt) 2012-04-20 2017-06-27 Hyperion Therapeutics Inc métodos de monitoramento terapêutico de pró-fármacos de ácido fenilacético

Also Published As

Publication number Publication date
US20170354631A1 (en) 2017-12-14
PT2986325T (pt) 2019-10-09
US20170354632A1 (en) 2017-12-14
SMT201900542T1 (it) 2019-11-13
US20180021292A1 (en) 2018-01-25
US20150105469A1 (en) 2015-04-16
SI2986325T1 (sl) 2020-02-28
HK1219656A1 (en) 2017-04-13
EP2986325A4 (en) 2016-07-27
LT2986325T (lt) 2019-10-10
EP2986325A1 (en) 2016-02-24
US20160074356A1 (en) 2016-03-17
US20200405678A1 (en) 2020-12-31
RS59429B1 (sr) 2019-11-29
DK2986325T3 (da) 2019-09-23
CY1122220T1 (el) 2020-11-25
WO2015057747A1 (en) 2015-04-23
US20180015065A1 (en) 2018-01-18
EP2986325B1 (en) 2019-06-26
ES2746999T3 (es) 2020-03-09
HRP20191710T1 (hr) 2019-12-13
HUE045106T2 (hu) 2019-12-30

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