PL3024468T3 - Receptory limfocytów T - Google Patents

Receptory limfocytów T

Info

Publication number
PL3024468T3
PL3024468T3 PL14748262T PL14748262T PL3024468T3 PL 3024468 T3 PL3024468 T3 PL 3024468T3 PL 14748262 T PL14748262 T PL 14748262T PL 14748262 T PL14748262 T PL 14748262T PL 3024468 T3 PL3024468 T3 PL 3024468T3
Authority
PL
Poland
Prior art keywords
cell receptors
receptors
cell
Prior art date
Application number
PL14748262T
Other languages
English (en)
Inventor
Peter Molloy
Nicholas Jonathan Pumphrey
Original Assignee
Adaptimmune Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adaptimmune Limited filed Critical Adaptimmune Limited
Publication of PL3024468T3 publication Critical patent/PL3024468T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4264—Cancer antigens from embryonic or fetal origin
    • A61K40/4265—Alpha-feto protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL14748262T 2013-07-26 2014-07-18 Receptory limfocytów T PL3024468T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1313377.2A GB201313377D0 (en) 2013-07-26 2013-07-26 T cell receptors
PCT/GB2014/052199 WO2015011450A1 (en) 2013-07-26 2014-07-18 T cell receptors
EP14748262.4A EP3024468B1 (en) 2013-07-26 2014-07-18 T cell receptors

Publications (1)

Publication Number Publication Date
PL3024468T3 true PL3024468T3 (pl) 2019-12-31

Family

ID=49166992

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14748262T PL3024468T3 (pl) 2013-07-26 2014-07-18 Receptory limfocytów T

Country Status (22)

Country Link
US (4) US10344074B2 (pl)
EP (2) EP3578188B1 (pl)
JP (3) JP6635311B2 (pl)
KR (2) KR20210073612A (pl)
CN (2) CN105408353B (pl)
AU (2) AU2014294830B2 (pl)
CA (1) CA2916027C (pl)
CY (1) CY1121962T1 (pl)
DK (2) DK3024468T3 (pl)
ES (2) ES2734190T3 (pl)
GB (1) GB201313377D0 (pl)
HR (1) HRP20191371T1 (pl)
HU (1) HUE045399T2 (pl)
LT (1) LT3024468T (pl)
NZ (1) NZ715038A (pl)
PL (1) PL3024468T3 (pl)
PT (1) PT3024468T (pl)
RS (1) RS59177B1 (pl)
SG (1) SG11201510157YA (pl)
SI (1) SI3024468T1 (pl)
SM (1) SMT201900424T1 (pl)
WO (1) WO2015011450A1 (pl)

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GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
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Also Published As

Publication number Publication date
ES2912743T3 (es) 2022-05-27
EP3578188A1 (en) 2019-12-11
SI3024468T1 (sl) 2019-10-30
DK3578188T3 (da) 2022-05-02
HRP20191371T1 (hr) 2019-11-01
KR20160034329A (ko) 2016-03-29
US11084862B2 (en) 2021-08-10
RS59177B1 (sr) 2019-10-31
ES2734190T3 (es) 2019-12-04
LT3024468T (lt) 2019-09-25
AU2014294830A1 (en) 2016-01-21
DK3024468T3 (da) 2019-07-22
HK1222338A1 (en) 2017-06-30
AU2014294830B2 (en) 2020-01-16
HUE045399T2 (hu) 2019-12-30
US20210324036A1 (en) 2021-10-21
EP3578188B1 (en) 2022-02-23
JP2020054364A (ja) 2020-04-09
KR102267345B1 (ko) 2021-06-22
SG11201510157YA (en) 2016-02-26
CN105408353A (zh) 2016-03-16
CN111153984A (zh) 2020-05-15
AU2020202538A1 (en) 2020-05-07
JP2021151248A (ja) 2021-09-30
JP6635311B2 (ja) 2020-01-22
US20160137715A1 (en) 2016-05-19
KR20210073612A (ko) 2021-06-18
EP3024468B1 (en) 2019-05-08
US20250122263A1 (en) 2025-04-17
JP6956164B2 (ja) 2021-10-27
EP3024468A1 (en) 2016-06-01
PT3024468T (pt) 2019-08-01
JP2016525537A (ja) 2016-08-25
NZ715038A (en) 2021-12-24
GB201313377D0 (en) 2013-09-11
US10344074B2 (en) 2019-07-09
CN105408353B (zh) 2020-05-19
WO2015011450A1 (en) 2015-01-29
CY1121962T1 (el) 2020-10-14
SMT201900424T1 (it) 2019-11-13
CA2916027C (en) 2022-11-29
CA2916027A1 (en) 2015-01-29
US20190330301A1 (en) 2019-10-31

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