PL3108009T3 - Sposoby i kompozycje do profilowania dna - Google Patents

Sposoby i kompozycje do profilowania dna

Info

Publication number
PL3108009T3
PL3108009T3 PL15708379T PL15708379T PL3108009T3 PL 3108009 T3 PL3108009 T3 PL 3108009T3 PL 15708379 T PL15708379 T PL 15708379T PL 15708379 T PL15708379 T PL 15708379T PL 3108009 T3 PL3108009 T3 PL 3108009T3
Authority
PL
Poland
Prior art keywords
compositions
methods
dna profiling
profiling
dna
Prior art date
Application number
PL15708379T
Other languages
English (en)
Inventor
Kathryn M. Stephens
Cydne HOLT
Carey DAVIS
Anne JAGER
Paulina Walichiewicz
Yonmee HAN
David Silva
Min-Jui Richard Shen
Sasan Amini
Frank Steemers
Original Assignee
Illumina, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina, Inc. filed Critical Illumina, Inc.
Publication of PL3108009T3 publication Critical patent/PL3108009T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
    • C12Q2522/10—Nucleic acid binding proteins
    • C12Q2522/101—Single or double stranded nucleic acid binding proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/204—Modifications characterised by specific length of the oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/107—Temperature of melting, i.e. Tm
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
PL15708379T 2014-02-18 2015-02-13 Sposoby i kompozycje do profilowania dna PL3108009T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461940942P 2014-02-18 2014-02-18
US201462043060P 2014-08-28 2014-08-28
US201562103524P 2015-01-14 2015-01-14
EP15708379.1A EP3108009B1 (en) 2014-02-18 2015-02-13 Methods and compositions for dna profiling
PCT/US2015/015939 WO2015126766A1 (en) 2014-02-18 2015-02-13 Methods and compositions for dna profiling

Publications (1)

Publication Number Publication Date
PL3108009T3 true PL3108009T3 (pl) 2021-10-11

Family

ID=52629678

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15708379T PL3108009T3 (pl) 2014-02-18 2015-02-13 Sposoby i kompozycje do profilowania dna

Country Status (22)

Country Link
US (2) US10422002B2 (pl)
EP (2) EP3108009B1 (pl)
JP (3) JP7011392B2 (pl)
CN (1) CN106164298B (pl)
AU (2) AU2015219289B2 (pl)
BR (2) BR112016019267B8 (pl)
CA (1) CA2940048C (pl)
DK (1) DK3108009T3 (pl)
ES (1) ES2866044T3 (pl)
HR (1) HRP20210953T1 (pl)
HU (1) HUE055256T2 (pl)
LT (1) LT3108009T (pl)
MX (1) MX379233B (pl)
MY (2) MY200537A (pl)
NZ (1) NZ723399A (pl)
PL (1) PL3108009T3 (pl)
PT (1) PT3108009T (pl)
RS (1) RS61976B1 (pl)
RU (2) RU2708337C2 (pl)
SA (1) SA516371691B1 (pl)
SI (1) SI3108009T1 (pl)
WO (1) WO2015126766A1 (pl)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1219044A1 (zh) * 2013-03-15 2017-03-24 艾伯维德国有限责任两合公司 抗egfr抗体药物偶联物制剂
SI3108009T1 (sl) * 2014-02-18 2021-09-30 Illumina, Inc. Postopki in sestavki za profiliranje DNK
US9857328B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same
US10020300B2 (en) 2014-12-18 2018-07-10 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US9859394B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US10429342B2 (en) 2014-12-18 2019-10-01 Edico Genome Corporation Chemically-sensitive field effect transistor
ES2961374T3 (es) * 2015-04-24 2024-03-11 Atila Biosystems Incorporated Amplificación con cebadores de composición de nucleótidos limitada
CN105755129B (zh) * 2016-03-21 2020-03-31 北京市理化分析测试中心 基于新一代测序的基因座d8s1179的str分型方法
WO2017196720A1 (en) * 2016-05-13 2017-11-16 Colorado State University Research Foundation High throughput method to genotype plants
WO2017201081A1 (en) 2016-05-16 2017-11-23 Agilome, Inc. Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids
US10822647B2 (en) * 2016-07-12 2020-11-03 Biodynamics S.R.L. Methods for using long ssDNA polynucleotides as primers (superprimers) in PCR assays
CN110312825A (zh) * 2016-10-24 2019-10-08 吉内恩福赛克公司 隐藏核酸内存在的信息
CN118638898A (zh) * 2017-03-23 2024-09-13 华盛顿大学 用于靶向核酸序列富集的方法及在错误纠正的核酸测序中的应用
CN106835292B (zh) * 2017-04-05 2019-04-09 北京泛生子基因科技有限公司 一步法快速构建扩增子文库的方法
CN111148846B (zh) 2017-05-05 2024-06-18 西比欧生物科学公司 在水凝胶中捕获离散生物单元并使其条码化的方法
EP3631054A4 (en) * 2017-05-23 2021-03-03 President and Fellows of Harvard College MULTIPLEX END MARKING AMPLIFICATION OF NUCLEIC ACIDS
WO2018236631A1 (en) 2017-06-20 2018-12-27 Illumina, Inc. METHODS AND COMPOSITIONS FOR RESOLVING INEFFICIENCY IN AMPLIFICATION REACTIONS
US11739375B2 (en) 2017-08-11 2023-08-29 Atila Biosystems Incorporated Digital amplification with primers of limited nucleotide composition
CN107868837B (zh) * 2017-12-12 2019-03-01 苏州普瑞森基因科技有限公司 一种用于分析肠道微生物的引物组合物及其应用
CN109988826A (zh) * 2017-12-30 2019-07-09 安诺优达基因科技(北京)有限公司 一种基于str计算混合样本嵌合比例的方法以及系统
EP3517629A1 (en) * 2018-01-30 2019-07-31 Myway Genetics S.r.L. Use of cfdna fragments as biomarkers in patients after organ transplantation
CN108342469A (zh) * 2018-02-27 2018-07-31 广州中安基因科技有限公司 一种皮肤基因检测的基因芯片
US12142104B2 (en) 2018-03-22 2024-11-12 President And Fellows Of Harvard College Methods and compositions for molecular authentication
JP6646120B1 (ja) * 2018-10-01 2020-02-14 日本ソフトウェアマネジメント株式会社 分解されたdnaで個体識別可能なdna鑑定方法
KR102097721B1 (ko) * 2019-01-24 2020-04-06 주식회사 시선바이오머티리얼스 태그서열 snp를 이용한 단일 검출 프로브 기반 다중 표적 검출방법
CN111485024B (zh) * 2019-01-29 2024-04-26 深圳华大法医科技有限公司 用于个体特征确认的引物组合、及其应用
KR102351579B1 (ko) * 2019-06-25 2022-01-17 대한민국 상염색체 str 좌위를 포함한 ngs 패널 및 다중증폭 시스템
WO2021048393A1 (en) * 2019-09-11 2021-03-18 Parlanca Limited A multiplex method of preparing a sequencing library
CA3176620A1 (en) * 2020-03-31 2021-10-07 Personal Genome Diagnostics Inc. Compositions and methods for nucleic acid quality determination
CN116547390A (zh) * 2020-11-02 2023-08-04 阅尔基因美国公司 定量多重扩增子测序系统
CN112592981B (zh) * 2020-12-01 2023-06-20 广州精科医学检验所有限公司 用于dna档案建库的引物组、试剂盒和方法
CN112342303A (zh) * 2020-12-04 2021-02-09 郑州高新生物技术有限公司 一种基于ngs的人类y染色体str和snp遗传标记联合检测体系及检测方法
CN112852970A (zh) * 2020-12-31 2021-05-28 百特元生物科技(北京)有限公司 一种同时扩增人37个y-str基因座的引物组、试剂盒及其应用
US20240117336A1 (en) 2021-02-12 2024-04-11 Verogen, Inc. Methods and compositions for dna based kinship analysis
CN113293205B (zh) * 2021-05-24 2024-11-26 深圳市真迈生物科技有限公司 测序方法
KR102337267B1 (ko) * 2021-06-01 2021-12-08 주식회사 다우진유전자연구소 유전자 감식을 위한 24개의 str 유전자 마커를 이용한 pcr 다중증폭 시스템
CN113930490B (zh) * 2021-09-27 2024-09-10 江汉大学 二代测序平台中利用分子特异性条形码评估str滑脱的方法及其应用
US20240412816A1 (en) * 2021-10-13 2024-12-12 Verogen, Inc. Methods and compositions for improving accuracy of dna based kinship analysis
EP4272764A1 (en) 2022-05-03 2023-11-08 Scipio Bioscience Method of complexing biological units with particles
JP2025530659A (ja) 2022-08-16 2025-09-17 ベロジェン・インコーポレイテッド 行方不明者および災害/紛争犠牲者のための血縁関係評価のための方法およびシステム
EP4599059A4 (en) * 2022-10-21 2026-03-04 Watchmaker Genomics Inc METHODS AND COMPOSITIONS FOR NORMALIZING SEQUALIZATION LIBRARIES
EP4603595A1 (en) * 2024-02-13 2025-08-20 ImmuneDiscover Sweden AB A method for typing the immune genes and the allelic variants thereof

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006678A1 (en) 1989-10-26 1991-05-16 Sri International Dna sequencing
US5846719A (en) 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
EP2327797B1 (en) 1997-04-01 2015-11-25 Illumina Cambridge Limited Method of nucleic acid sequencing
US6969488B2 (en) 1998-05-22 2005-11-29 Solexa, Inc. System and apparatus for sequential processing of analytes
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
GB9929381D0 (en) * 1999-12-10 2000-02-09 Pyrosequencing Ab A method of assessing the amount of nucleic acid in a sample
US7001792B2 (en) 2000-04-24 2006-02-21 Eagle Research & Development, Llc Ultra-fast nucleic acid sequencing device and a method for making and using the same
EP2100971A3 (en) 2000-07-07 2009-11-25 Visigen Biotechnologies, Inc. Real-time sequence determination
US7211414B2 (en) 2000-12-01 2007-05-01 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US7078168B2 (en) * 2001-02-27 2006-07-18 Biotage Ab Method for determining allele frequencies
JP4210769B2 (ja) * 2001-11-22 2009-01-21 独立行政法人産業技術総合研究所 Gatewayエントリークローンの作製方法
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
AU2003259350A1 (en) 2002-08-23 2004-03-11 Solexa Limited Modified nucleotides for polynucleotide sequencing
GB0321306D0 (en) 2003-09-11 2003-10-15 Solexa Ltd Modified polymerases for improved incorporation of nucleotide analogues
EP2789383B1 (en) 2004-01-07 2023-05-03 Illumina Cambridge Limited Molecular arrays
WO2006004659A1 (en) 2004-06-30 2006-01-12 Applera Corporation Methods for analyzing short tandem repeats and single nucleotide polymorphisms
US20060057595A1 (en) * 2004-09-16 2006-03-16 Applera Corporation Compositions, methods, and kits for identifying and quantitating small RNA molecules
US7315019B2 (en) 2004-09-17 2008-01-01 Pacific Biosciences Of California, Inc. Arrays of optical confinements and uses thereof
WO2006064199A1 (en) 2004-12-13 2006-06-22 Solexa Limited Improved method of nucleotide detection
JP4990886B2 (ja) 2005-05-10 2012-08-01 ソレックサ リミテッド 改良ポリメラーゼ
GB0514936D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Preparation of templates for nucleic acid sequencing
US7405281B2 (en) 2005-09-29 2008-07-29 Pacific Biosciences Of California, Inc. Fluorescent nucleotide analogs and uses therefor
SG170802A1 (en) 2006-03-31 2011-05-30 Solexa Inc Systems and devices for sequence by synthesis analysis
WO2008111990A1 (en) * 2006-06-14 2008-09-18 Cellpoint Diagnostics, Inc. Rare cell analysis using sample splitting and dna tags
EP2089517A4 (en) 2006-10-23 2010-10-20 Pacific Biosciences California POLYMERASEENZYME AND REAGENTS FOR ADVANCED NUCKIC ACID SEQUENCING
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
EP2677309B9 (en) 2006-12-14 2014-11-19 Life Technologies Corporation Methods for sequencing a nucleic acid using large scale FET arrays, configured to measure a limited pH range
US9434997B2 (en) * 2007-08-24 2016-09-06 Lawrence Livermore National Security, Llc Methods, compounds and systems for detecting a microorganism in a sample
US20090163366A1 (en) * 2007-12-24 2009-06-25 Helicos Biosciences Corporation Two-primer sequencing for high-throughput expression analysis
WO2009114543A2 (en) * 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
AU2011207544A1 (en) 2010-01-19 2012-09-06 Verinata Health, Inc. Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
NZ735051A (en) * 2011-05-12 2022-11-25 Netbio Inc Methods and compositions for rapid multiplex amplification of str loci
US9453258B2 (en) 2011-09-23 2016-09-27 Illumina, Inc. Methods and compositions for nucleic acid sequencing
JP6159391B2 (ja) 2012-04-03 2017-07-05 イラミーナ インコーポレーテッド 核酸シークエンシングに有用な統合化した読取りヘッド及び流体カートリッジ
EP2867366B1 (en) * 2012-06-29 2018-05-16 General Electric Company Method for isothermal dna amplification starting from an rna template in a single reaction mixture
SI3108009T1 (sl) * 2014-02-18 2021-09-30 Illumina, Inc. Postopki in sestavki za profiliranje DNK

Also Published As

Publication number Publication date
US20150232929A1 (en) 2015-08-20
PT3108009T (pt) 2021-05-10
HUE055256T2 (hu) 2021-11-29
NZ761724A (en) 2024-04-26
SI3108009T1 (sl) 2021-09-30
US10422002B2 (en) 2019-09-24
EP3910069A1 (en) 2021-11-17
JP7770437B2 (ja) 2025-11-14
BR112016019267B8 (pt) 2023-01-10
RU2752700C2 (ru) 2021-07-30
RU2016133987A3 (pl) 2018-12-19
AU2021203877B2 (en) 2023-11-23
JP2021177777A (ja) 2021-11-18
HRP20210953T1 (hr) 2021-09-03
BR112016019267B1 (pt) 2022-06-28
CN106164298A (zh) 2016-11-23
CN106164298B (zh) 2020-02-21
EP3108009B1 (en) 2021-03-24
SA516371691B1 (ar) 2022-03-20
EP3108009A1 (en) 2016-12-28
MX2016010717A (es) 2017-04-27
DK3108009T3 (da) 2021-06-07
RU2019138698A3 (pl) 2020-06-19
RS61976B1 (sr) 2021-07-30
RU2016133987A (ru) 2018-03-27
RU2708337C2 (ru) 2019-12-05
ES2866044T3 (es) 2021-10-19
AU2021203877A1 (en) 2021-07-08
US11530446B2 (en) 2022-12-20
WO2015126766A8 (en) 2016-11-03
MX379233B (es) 2025-03-10
BR112016019267A2 (pt) 2017-10-10
JP2017509329A (ja) 2017-04-06
US20200224268A1 (en) 2020-07-16
AU2015219289A1 (en) 2016-09-08
NZ723399A (en) 2020-08-28
MY182415A (en) 2021-01-25
BR122022007092B8 (pt) 2023-01-31
WO2015126766A1 (en) 2015-08-27
RU2019138698A (ru) 2020-01-27
BR122022007092B1 (pt) 2022-07-19
CA2940048A1 (en) 2016-08-27
AU2015219289B2 (en) 2021-05-06
MY200537A (en) 2024-01-02
CA2940048C (en) 2023-03-14
JP7011392B2 (ja) 2022-01-26
LT3108009T (lt) 2021-07-12
JP2024059651A (ja) 2024-05-01

Similar Documents

Publication Publication Date Title
IL287113A (en) smyd inhibitors
PT3108009T (pt) Métodos e composições para a criação de perfis de adn
IL258230A (en) Oligonucleotide compositions and methods thereof
IL256603A (en) Preparations of oligonucleotides and methods
GB2535253B (en) Compositions and methods
SG10202109655VA (en) Compositions and methods for immunooncology
SG11201608503UA (en) Methods and compositions for modifying genomic dna
IL246785A0 (en) Benzimidazole-2-amines as midh1 inhibitors
LT3215147T (lt) Neurologinį poveikį mažinantys norketamino junginiai ir būdai
IL251420A0 (en) Triazolopyrazinones as pde1 inhibitors
IL248895A0 (en) Phosphatidylinositol 3-kinase inhibitors
IL246879A0 (en) Preparations of Epilimod and methods of using them
GB201413086D0 (en) Methods
GB201417828D0 (en) New methods and compositions
GB201418892D0 (en) DNA editing
IL251107A0 (en) Compounds and methods
ZA201607571B (en) Compositions and methods for detecting huanglongbing
ZA201703771B (en) Compositions and methods for treating hyperkalemia
GB201408745D0 (en) Methods
IL246718A0 (en) Hexahydrofuropyrroles as pde1 inhibitors
SG11201610970UA (en) Compositions and methods for enhancing immunity
PL2990058T3 (pl) Ulepszone kompozycje i sposoby dla kompleksów fruktoboranowych
PT3210628T (pt) Métodos para complexos de frutoborato
GB201402915D0 (en) Compositions and methods
GB201415685D0 (en) Methods