PL3117012T5 - Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu - Google Patents
Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepuInfo
- Publication number
- PL3117012T5 PL3117012T5 PL15761889.3T PL15761889T PL3117012T5 PL 3117012 T5 PL3117012 T5 PL 3117012T5 PL 15761889 T PL15761889 T PL 15761889T PL 3117012 T5 PL3117012 T5 PL 3117012T5
- Authority
- PL
- Poland
- Prior art keywords
- methods
- transplant recipients
- immunosuppressive therapies
- monitoring
- monitoring immunosuppressive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953582P | 2014-03-14 | 2014-03-14 | |
| EP15761889.3A EP3117012B2 (en) | 2014-03-14 | 2015-03-13 | Methods of monitoring immunosuppressive therapies in a transplant recipient |
| PCT/US2015/020603 WO2015138997A1 (en) | 2014-03-14 | 2015-03-13 | Methods of monitoring immunosuppressive therapies in a transplant recipient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL3117012T3 PL3117012T3 (pl) | 2019-08-30 |
| PL3117012T5 true PL3117012T5 (pl) | 2026-03-16 |
Family
ID=54072508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15761889.3T PL3117012T5 (pl) | 2014-03-14 | 2015-03-13 | Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu |
Country Status (16)
| Country | Link |
|---|---|
| US (12) | US11767559B2 (pl) |
| EP (1) | EP3117012B2 (pl) |
| CN (2) | CN113528645A (pl) |
| AU (3) | AU2015229083B2 (pl) |
| BR (1) | BR112016021038B1 (pl) |
| CA (1) | CA2970916C (pl) |
| DK (1) | DK3117012T4 (pl) |
| ES (1) | ES2726650T5 (pl) |
| FI (1) | FI3117012T4 (pl) |
| HR (1) | HRP20190759T4 (pl) |
| HU (1) | HUE043288T2 (pl) |
| PL (1) | PL3117012T5 (pl) |
| PT (1) | PT3117012T (pl) |
| SI (1) | SI3117012T2 (pl) |
| TR (1) | TR201907106T4 (pl) |
| WO (1) | WO2015138997A1 (pl) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| ES2640776T3 (es) | 2009-09-30 | 2017-11-06 | Natera, Inc. | Métodos para denominar de forma no invasiva ploidía prenatal |
| US12655483B2 (en) | 2010-05-18 | 2026-06-16 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) * | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| EP2854058A3 (en) | 2010-05-18 | 2015-10-28 | Natera, Inc. | Methods for non-invasive pre-natal ploidy calling |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11332785B2 (en) * | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190284623A1 (en) * | 2010-05-18 | 2019-09-19 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| AU2011348100B2 (en) | 2010-12-22 | 2016-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| PL3004388T5 (pl) | 2013-05-29 | 2023-10-09 | Chronix Biomedical | Wykrywanie i oznaczanie ilościowe pozakomórkowego dna dawcy w układzie krążenia biorców przeszczepów organów |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| PL3117012T5 (pl) | 2014-03-14 | 2026-03-16 | Caredx, Inc. | Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| RU2717641C2 (ru) | 2014-04-21 | 2020-03-24 | Натера, Инк. | Обнаружение мутаций и плоидности в хромосомных сегментах |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| EP3164503B1 (en) | 2014-07-03 | 2024-08-28 | Agilent Technologies, Inc. | Methods for non-invasive detection of transplant health or rejection |
| EP4428863A3 (en) | 2015-05-11 | 2024-12-11 | Natera, Inc. | Methods and compositions for determining ploidy |
| CN106544407B (zh) * | 2015-09-18 | 2019-11-08 | 广州华大基因医学检验所有限公司 | 确定受体cfDNA样本中供体来源cfDNA比例的方法 |
| CN105483123B (zh) * | 2015-11-23 | 2019-02-22 | 元码基因科技(北京)股份有限公司 | 遗传标记组合、个体基因身份证及其用途 |
| JP7280044B2 (ja) | 2016-04-15 | 2023-05-23 | ナテラ, インコーポレイテッド | 肺癌の検出方法 |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| US20190367972A1 (en) * | 2016-11-02 | 2019-12-05 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total and specific cell-free dna |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| CN106520982B (zh) * | 2016-12-05 | 2019-11-08 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种用于身份鉴定的复合分型系统 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| CN107058562B (zh) * | 2017-05-17 | 2018-04-10 | 成都仕康美生物科技有限公司 | Snp位点的应用及其检测试剂盒 |
| CN110945136A (zh) | 2017-06-20 | 2020-03-31 | 威斯康星州立大学医学院 | 使用总无细胞dna评估移植并发症风险 |
| US20210139983A1 (en) * | 2017-06-20 | 2021-05-13 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| SG11202005474RA (en) * | 2017-12-15 | 2020-07-29 | Acrannolife Genomics Pvt Ltd | A non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| EP3737773B1 (en) | 2018-01-12 | 2023-04-12 | Natera, Inc. | Novel primers and uses thereof |
| CN107937571B (zh) * | 2018-01-16 | 2021-12-07 | 良培基因生物科技(武汉)有限公司 | 一种基于信息snp集及其引物的核酸质谱亲权鉴定方法 |
| EP3517629A1 (en) | 2018-01-30 | 2019-07-31 | Myway Genetics S.r.L. | Use of cfdna fragments as biomarkers in patients after organ transplantation |
| WO2019161244A1 (en) | 2018-02-15 | 2019-08-22 | Natera, Inc. | Methods for isolating nucleic acids with size selection |
| DK3781714T3 (da) | 2018-04-14 | 2026-03-30 | Natera Inc | Fremgangsmåder til cancerpåvisning og -overvågning ved personlig påvisning af cirkulerende tumor-dna |
| CN112752852A (zh) * | 2018-07-03 | 2021-05-04 | 纳特拉公司 | 用于检测供体来源的细胞游离dna的方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| EP3847280A1 (en) | 2018-09-07 | 2021-07-14 | Sequenom, Inc. | Methods, and systems to detect transplant rejection |
| US20200109449A1 (en) * | 2018-10-09 | 2020-04-09 | Tai Diagnostics, Inc. | Cell lysis assay for cell-free dna analysis |
| US20220073989A1 (en) * | 2018-12-20 | 2022-03-10 | The Regents Of The University Of California | Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA |
| US20220093208A1 (en) * | 2019-02-19 | 2022-03-24 | Sequenom, Inc. | Compositions, methods, and systems to detect hematopoietic stem cell transplantation status |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| EP4106872B1 (en) * | 2020-03-06 | 2026-07-15 | Denovo Biopharma LLC | Compositions and methods for assessing the efficacy of inhibitors of neurotransmitter transporters |
| US20210395835A1 (en) * | 2020-06-19 | 2021-12-23 | Caredx, Inc. | Methods for monitoring allogeneic cells |
| CN113061666A (zh) * | 2020-12-30 | 2021-07-02 | 中南大学湘雅二医院 | 肝移植后巨细胞病毒的检测方法、应用及系统 |
| US20220356521A1 (en) * | 2021-04-30 | 2022-11-10 | Caredx, Inc. | Methods for detecting, monitoring, and guiding treatment of allograft rejection using discriminating gene expression signatures |
| US20240279720A1 (en) * | 2021-07-23 | 2024-08-22 | Georgetown University | Use of genetic and epigenetic markers to detect cell death |
| CA3227761A1 (en) * | 2021-07-29 | 2023-02-02 | Northwestern University | Methods, systems, and compositions for diagnosing transplant rejection |
| CN118922560A (zh) * | 2022-03-21 | 2024-11-08 | 凯尔迪克斯公司 | 用于在跨物种移植中非侵入性监测器官健康的方法 |
| US20230338419A1 (en) * | 2022-03-21 | 2023-10-26 | The Trustees Of The University Of Pennsylvania | Methods and apparatus for diagnosis and detection of cardiac allograft vasculopathy |
Family Cites Families (158)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6401267B1 (en) | 1993-09-27 | 2002-06-11 | Radoje Drmanac | Methods and compositions for efficient nucleic acid sequencing |
| USRE39920E1 (en) * | 1997-05-30 | 2007-11-13 | Xenomics, Inc. | Methods for detection of nucleic acid sequences in urine |
| US6132997A (en) | 1999-05-28 | 2000-10-17 | Agilent Technologies | Method for linear mRNA amplification |
| US7403972B1 (en) | 2002-04-24 | 2008-07-22 | Ip Venture, Inc. | Method and system for enhanced messaging |
| US20020197630A1 (en) | 2001-04-12 | 2002-12-26 | Knapp Michael R. | Systems and methods for high throughput genetic analysis |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
| US7727720B2 (en) | 2002-05-08 | 2010-06-01 | Ravgen, Inc. | Methods for detection of genetic disorders |
| US10229244B2 (en) | 2002-11-11 | 2019-03-12 | Affymetrix, Inc. | Methods for identifying DNA copy number changes using hidden markov model based estimations |
| EP1689884A4 (en) | 2003-10-08 | 2007-04-04 | Univ Boston | PROCESS FOR THE PRENATAL DIAGNOSIS OF CHROMOSOMAL ABNORMALITIES |
| US7149658B2 (en) | 2004-02-02 | 2006-12-12 | United Parcel Service Of America, Inc. | Systems and methods for transporting a product using an environmental sensor |
| US8024128B2 (en) | 2004-09-07 | 2011-09-20 | Gene Security Network, Inc. | System and method for improving clinical decisions by aggregating, validating and analysing genetic and phenotypic data |
| US7645575B2 (en) | 2004-09-08 | 2010-01-12 | Xdx, Inc. | Genes useful for diagnosing and monitoring inflammation related disorders |
| US20060228721A1 (en) | 2005-04-12 | 2006-10-12 | Leamon John H | Methods for determining sequence variants using ultra-deep sequencing |
| US8532930B2 (en) | 2005-11-26 | 2013-09-10 | Natera, Inc. | Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20070027636A1 (en) | 2005-07-29 | 2007-02-01 | Matthew Rabinowitz | System and method for using genetic, phentoypic and clinical data to make predictions for clinical or lifestyle decisions |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8515679B2 (en) | 2005-12-06 | 2013-08-20 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20070178501A1 (en) | 2005-12-06 | 2007-08-02 | Matthew Rabinowitz | System and method for integrating and validating genotypic, phenotypic and medical information into a database according to a standardized ontology |
| AU2007309726A1 (en) | 2006-04-07 | 2008-05-02 | Xdx, Inc. | Steroid responsive nucleic acid expression and prediction of disease activity |
| WO2008021431A2 (en) | 2006-08-14 | 2008-02-21 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders |
| CA2668608A1 (en) | 2006-11-08 | 2008-06-05 | Aldagen, Inc. | Methods for using aldhbr cells to supplement stem cell transplantation |
| US12054776B2 (en) | 2007-07-23 | 2024-08-06 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using massively parallel genomic sequencing |
| US9370689B2 (en) | 2008-01-07 | 2016-06-21 | The Quantum Group, Inc. | System and methods for providing dynamic integrated wellness assessment |
| US20110033862A1 (en) | 2008-02-19 | 2011-02-10 | Gene Security Network, Inc. | Methods for cell genotyping |
| US20110092763A1 (en) | 2008-05-27 | 2011-04-21 | Gene Security Network, Inc. | Methods for Embryo Characterization and Comparison |
| US20160371432A1 (en) | 2008-05-27 | 2016-12-22 | Natera, Inc. | Methods for allele calling and ploidy calling |
| ES2532153T3 (es) * | 2008-07-18 | 2015-03-24 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
| CN104732118B (zh) | 2008-08-04 | 2017-08-22 | 纳特拉公司 | 等位基因调用和倍性调用的方法 |
| WO2010027870A2 (en) | 2008-08-26 | 2010-03-11 | Fluidigm Corporation | Assay methods for increased throughput of samples and/or targets |
| EP2364368B1 (en) * | 2008-11-07 | 2014-01-15 | Sequenta, Inc. | Methods of monitoring conditions by sequence analysis |
| EP3249053A1 (en) | 2009-03-27 | 2017-11-29 | Life Technologies Corporation | Methods, compositions, and kits for detecting allelic variants |
| ES2640776T3 (es) | 2009-09-30 | 2017-11-06 | Natera, Inc. | Métodos para denominar de forma no invasiva ploidía prenatal |
| DK2496720T3 (da) * | 2009-11-06 | 2020-09-28 | Univ Leland Stanford Junior | Ikke-invasiv diagnose af transplantatafstødning i organ-transplanterede patienter |
| US20110173023A1 (en) | 2010-01-12 | 2011-07-14 | Gryphes Inc. | Method and System for Managing Organ Transplant Transporation |
| US20140206552A1 (en) | 2010-05-18 | 2014-07-24 | Natera, Inc. | Methods for preimplantation genetic diagnosis by sequencing |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20130196862A1 (en) | 2010-05-18 | 2013-08-01 | Natera, Inc. | Informatics Enhanced Analysis of Fetal Samples Subject to Maternal Contamination |
| US20220356526A1 (en) | 2010-05-18 | 2022-11-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20130123120A1 (en) | 2010-05-18 | 2013-05-16 | Natera, Inc. | Highly Multiplex PCR Methods and Compositions |
| EP2854058A3 (en) | 2010-05-18 | 2015-10-28 | Natera, Inc. | Methods for non-invasive pre-natal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20120034603A1 (en) * | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
| US20180344215A1 (en) | 2015-11-24 | 2018-12-06 | Dacadoo Ag | Automated health data acquisition, processing and communication system and method |
| AU2011348100B2 (en) | 2010-12-22 | 2016-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US10131947B2 (en) * | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
| CN102618626B (zh) * | 2011-01-30 | 2014-05-14 | 杭州优思达生物技术有限公司 | 一种快速单核苷酸多态性的检测方法及试剂盒 |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| US20130024127A1 (en) | 2011-07-19 | 2013-01-24 | John Stuelpnagel | Determination of source contributions using binomial probability calculations |
| CA3069089A1 (en) | 2011-09-22 | 2013-03-28 | Lineage Biosciences, Inc. | Compositions and methods for analyzing heterogeneous samples |
| AU2012321053B2 (en) | 2011-10-07 | 2018-04-19 | Murdoch Childrens Research Institute | Diagnostic assay for tissue transplantation status |
| US8977373B2 (en) | 2011-12-28 | 2015-03-10 | Caterpillar Inc. | Systems and methods for extending physical sensor range using virtual sensors |
| CN103374518B (zh) * | 2012-04-12 | 2018-03-27 | 维里纳塔健康公司 | 拷贝数变异的检测和分类 |
| US10385396B2 (en) | 2012-04-19 | 2019-08-20 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| US20150154352A1 (en) | 2012-06-21 | 2015-06-04 | Gigagen, Inc. | System and Methods for Genetic Analysis of Mixed Cell Populations |
| US20150203916A1 (en) | 2012-06-27 | 2015-07-23 | Music Foundation For Research Development | Plasma analytes predict diagnosis and prognosis of thoracic aortic aneurysm |
| US20140051585A1 (en) | 2012-08-15 | 2014-02-20 | Natera, Inc. | Methods and compositions for reducing genetic library contamination |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| US20140065621A1 (en) | 2012-09-04 | 2014-03-06 | Natera, Inc. | Methods for increasing fetal fraction in maternal blood |
| US9852266B2 (en) | 2012-09-21 | 2017-12-26 | Md Revolution, Inc. | Interactive graphical user interfaces for implementing personalized health and wellness programs |
| WO2014074501A1 (en) | 2012-11-06 | 2014-05-15 | Quest Diagnostics Investments Incorporated | Molecular markers for diagnosis of acute cellular rejection and acute tubular necrosis |
| WO2014116729A2 (en) | 2013-01-22 | 2014-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Haplotying of hla loci with ultra-deep shotgun sequencing |
| WO2014180910A1 (en) | 2013-05-09 | 2014-11-13 | Roche Diagnostics Gmbh | Method of determining the fraction of fetal dna in maternal blood using hla markers |
| PL3004388T5 (pl) | 2013-05-29 | 2023-10-09 | Chronix Biomedical | Wykrywanie i oznaczanie ilościowe pozakomórkowego dna dawcy w układzie krążenia biorców przeszczepów organów |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US10262755B2 (en) | 2014-04-21 | 2019-04-16 | Natera, Inc. | Detecting cancer mutations and aneuploidy in chromosomal segments |
| WO2015048535A1 (en) | 2013-09-27 | 2015-04-02 | Natera, Inc. | Prenatal diagnostic resting standards |
| WO2015069933A1 (en) | 2013-11-06 | 2015-05-14 | The Board Of Trustees Of The Leland Stanford Junior University | Circulating cell-free dna for diagnosis of transplant rejection |
| WO2015085350A1 (en) | 2013-12-10 | 2015-06-18 | Conexio Genomics Pty Ltd | Methods and probes for identifying gene alleles |
| US9982301B2 (en) | 2014-01-07 | 2018-05-29 | Cornell University | Urine mRNA profile and acute dysfunction of kidney allograft |
| PL3117012T5 (pl) | 2014-03-14 | 2026-03-16 | Caredx, Inc. | Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu |
| US20250388965A1 (en) | 2014-03-14 | 2025-12-25 | Caredx, Inc. | Methods and systems for processing cell-free samples |
| RU2717641C2 (ru) | 2014-04-21 | 2020-03-24 | Натера, Инк. | Обнаружение мутаций и плоидности в хромосомных сегментах |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| AU2015296029B2 (en) | 2014-08-01 | 2022-01-27 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
| AU2016255573A1 (en) | 2015-04-30 | 2017-12-21 | The Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (MOMA)-real time PCR for assessing cell-free DNA |
| EP4428863A3 (en) | 2015-05-11 | 2024-12-11 | Natera, Inc. | Methods and compositions for determining ploidy |
| EP3307912B1 (en) | 2015-06-15 | 2021-09-15 | Murdoch Childrens Research Institute | Method of measuring chimerism |
| US20160371428A1 (en) | 2015-06-19 | 2016-12-22 | Natera, Inc. | Systems and methods for determining aneuploidy risk using sample fetal fraction |
| US9648446B2 (en) | 2015-09-22 | 2017-05-09 | Veniam, Inc. | Systems and methods for shipping management in a network of moving things |
| HUE044940T2 (hu) | 2016-01-27 | 2019-11-28 | Devyser Holding Ab | Kívánt nukleinsavrégiók szelektív amplifikálása egy célbavett szekvenciában |
| JP7280044B2 (ja) | 2016-04-15 | 2023-05-23 | ナテラ, インコーポレイテッド | 肺癌の検出方法 |
| CA3022572A1 (en) | 2016-04-29 | 2017-11-02 | The Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-target number |
| WO2018000031A1 (en) | 2016-06-27 | 2018-01-04 | Olivia Newton-John Cancer Research Institute | Use of cell free dna as a measure of organ health following transplantation |
| CA3025956A1 (en) | 2016-07-01 | 2018-01-04 | Natera, Inc. | Compositions and methods for detection of nucleic acid mutations |
| US10602964B2 (en) | 2016-08-17 | 2020-03-31 | Koninklijke Philips N.V. | Location, activity, and health compliance monitoring using multidimensional context analysis |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| US20190367972A1 (en) | 2016-11-02 | 2019-12-05 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total and specific cell-free dna |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| CA3049139A1 (en) | 2017-02-21 | 2018-08-30 | Natera, Inc. | Compositions, methods, and kits for isolating nucleic acids |
| JP6970205B2 (ja) * | 2017-03-08 | 2021-11-24 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Dnaおよびrnaの同時濃縮を含むプライマー伸長標的濃縮およびそれに対する向上 |
| EP3607088A4 (en) | 2017-04-04 | 2020-12-23 | The Board of Trustees of the Leland Stanford Junior University | QUANTIFICATION OF CIRCULATING ACELLULAR DNA DERIVED FROM TRANSPLANT IN THE ABSENCE OF A DONOR GENOTYPE |
| CN111094593A (zh) | 2017-06-20 | 2020-05-01 | 威斯康星州立大学医学院 | 使用供体特异性无细胞dna来评估移植对象中的病症 |
| CN110945136A (zh) | 2017-06-20 | 2020-03-31 | 威斯康星州立大学医学院 | 使用总无细胞dna评估移植并发症风险 |
| US11990208B2 (en) | 2017-06-20 | 2024-05-21 | Illumina, Inc. | Methods for accurate computational decomposition of DNA mixtures from contributors of unknown genotypes |
| US20210139983A1 (en) | 2017-06-20 | 2021-05-13 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| WO2018236911A1 (en) | 2017-06-20 | 2018-12-27 | Illumina, Inc. | Methods and systems for decomposition and quantification of dna mixtures from multiple contributors of known or unknown genotypes |
| CN111886015B (zh) | 2017-10-31 | 2024-04-26 | 艾洛基治疗公司 | 用于同种异体嵌合抗原受体t细胞的给药的方法和组合物 |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| SG11202005474RA (en) | 2017-12-15 | 2020-07-29 | Acrannolife Genomics Pvt Ltd | A non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| US11961033B2 (en) | 2018-01-05 | 2024-04-16 | Convey, Llc | System and method for dynamically scheduling API-based shipment updates across carriers |
| EP3737773B1 (en) | 2018-01-12 | 2023-04-12 | Natera, Inc. | Novel primers and uses thereof |
| EP3740173A4 (en) | 2018-01-19 | 2022-02-09 | University of Maryland, Baltimore | TECHNIQUES FOR HANDLING A HUMAN ORGAN DURING TRANSPORT |
| EP3517629A1 (en) | 2018-01-30 | 2019-07-31 | Myway Genetics S.r.L. | Use of cfdna fragments as biomarkers in patients after organ transplantation |
| WO2019161244A1 (en) | 2018-02-15 | 2019-08-22 | Natera, Inc. | Methods for isolating nucleic acids with size selection |
| WO2019178143A1 (en) | 2018-03-12 | 2019-09-19 | The Regents Of The University Of California | Assessing transplant rejection status by analysis of t-cell receptor subunit repertoire diversity |
| DK3781714T3 (da) | 2018-04-14 | 2026-03-30 | Natera Inc | Fremgangsmåder til cancerpåvisning og -overvågning ved personlig påvisning af cirkulerende tumor-dna |
| EP4194564A1 (en) | 2018-05-10 | 2023-06-14 | The Scripps Research Institute | Genome-wide classifiers for detection of subacute transplant rejection and other transplant conditions |
| WO2019241349A1 (en) | 2018-06-12 | 2019-12-19 | Natera, Inc. | Methods and systems for calling mutations |
| CN112752852A (zh) * | 2018-07-03 | 2021-05-04 | 纳特拉公司 | 用于检测供体来源的细胞游离dna的方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020018522A1 (en) | 2018-07-17 | 2020-01-23 | Natera, Inc. | Methods and systems for calling ploidy states using a neural network |
| US10402774B1 (en) | 2018-07-25 | 2019-09-03 | Capital One Services, LLP | Intelligence platform for automated retrieval or protection of a package or a person by an unmanned vehicle (UV) |
| EP3847280A1 (en) * | 2018-09-07 | 2021-07-14 | Sequenom, Inc. | Methods, and systems to detect transplant rejection |
| US20200109449A1 (en) | 2018-10-09 | 2020-04-09 | Tai Diagnostics, Inc. | Cell lysis assay for cell-free dna analysis |
| WO2020118046A1 (en) | 2018-12-05 | 2020-06-11 | William Marsh Rice University | Quantifying foreign dna in low-volume blood samples using snp profiling |
| EP3899033A4 (en) | 2018-12-17 | 2022-10-19 | The Medical College of Wisconsin, Inc. | Assessing risk with total cell-free dna |
| EP4617383A3 (en) | 2018-12-17 | 2025-12-24 | Natera, Inc. | Methods for analysis of circulating cells |
| US20220073989A1 (en) * | 2018-12-20 | 2022-03-10 | The Regents Of The University Of California | Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA |
| US20220081715A1 (en) | 2019-01-17 | 2022-03-17 | Katholieke Universiteit Leuven | mRNA-BASED BIOMARKERS FOR ANTIBODY-MEDIATED TRANSPLANT REJECTION |
| US20220093208A1 (en) | 2019-02-19 | 2022-03-24 | Sequenom, Inc. | Compositions, methods, and systems to detect hematopoietic stem cell transplantation status |
| EP3712898A1 (en) | 2019-03-21 | 2020-09-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method of predicting whether a kidney transplant recipient is at risk of having allograft loss |
| WO2020206290A1 (en) | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total cell-free dna |
| WO2020206292A2 (en) | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Assessing conditions in transplant subjects using donor-specific cell-free dna |
| CA3135853A1 (en) | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| EP3956466A1 (en) | 2019-04-15 | 2022-02-23 | Natera, Inc. | Improved liquid biopsy using size selection |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| WO2021021657A1 (en) | 2019-07-29 | 2021-02-04 | University Of Miami | System and method for ai-based eye condition determinations |
| US20220340963A1 (en) | 2019-09-20 | 2022-10-27 | Natera, Inc. | Methods for assessing graft suitability for transplantation |
| US20220392568A1 (en) | 2019-10-31 | 2022-12-08 | Caredx, Inc. | Method for identifying transplant donors for a transplant recipient |
| AU2020378435B2 (en) | 2019-11-06 | 2026-07-30 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for analyzing nucleic acid molecules |
| GB2612447B (en) | 2020-04-24 | 2025-08-13 | Univ Cornell | Methods for detecting tissue damage, graft versus host disease, and infections using cell-free DNA profiling |
| US20230203573A1 (en) | 2020-05-29 | 2023-06-29 | Natera, Inc. | Methods for detection of donor-derived cell-free dna |
| US11700847B2 (en) | 2020-06-06 | 2023-07-18 | MediGO, Inc. | Systems and methods for vital asset transport |
| US20210395835A1 (en) | 2020-06-19 | 2021-12-23 | Caredx, Inc. | Methods for monitoring allogeneic cells |
| WO2022015676A1 (en) | 2020-07-13 | 2022-01-20 | The Medical College Of Wisconsin, Inc. | Methods for making treatment management decisions in transplant subjects and assessing transplant risks with threshold values |
| WO2022035519A1 (en) | 2020-08-14 | 2022-02-17 | Caredx, Inc. | A system and methods for determining scores indicative of a transplant recipient's activities and behaviors |
| EP4298248A1 (en) | 2021-02-25 | 2024-01-03 | Natera, Inc. | Methods for detection of donor-derived cell-free dna in transplant recipients of multiple organs |
| AU2022261868A1 (en) | 2021-04-22 | 2023-10-26 | Natera, Inc. | Methods for determining velocity of tumor growth |
| EP4330425A4 (en) | 2021-04-29 | 2025-03-05 | The Medical College of Wisconsin, Inc. | METHODS FOR ASSESSING CELL OR TISSUE INJURY USING MITOCHONDRIAL AND/OR NUCLEAR CELL-FREE DNA |
| US20220356521A1 (en) | 2021-04-30 | 2022-11-10 | Caredx, Inc. | Methods for detecting, monitoring, and guiding treatment of allograft rejection using discriminating gene expression signatures |
| EP4402289B1 (en) | 2021-09-16 | 2026-04-01 | Northwestern University | Methods of using donor-derived cell-free dna to distinguish acute rejection and other conditions in liver transplant recipients |
| CN118804985A (zh) | 2021-12-22 | 2024-10-18 | 广州医科大学附属第一医院(广州呼吸中心) | 用于监测供体dna分数的方法 |
| CN118922560A (zh) | 2022-03-21 | 2024-11-08 | 凯尔迪克斯公司 | 用于在跨物种移植中非侵入性监测器官健康的方法 |
| CA3249433A1 (en) | 2022-04-29 | 2023-11-02 | Caredx, Inc. | SYSTEMS AND METHODS FOR CLASSIFYING THE STATE OF A GRAFTING |
| CN119301270A (zh) | 2022-06-03 | 2025-01-10 | 凯尔迪克斯公司 | 用于预测移植排斥的系统和方法 |
| JP2025006152A (ja) | 2023-06-29 | 2025-01-17 | キヤノン株式会社 | 光電変換装置、機器、および信号処理方法 |
-
2015
- 2015-03-13 PL PL15761889.3T patent/PL3117012T5/pl unknown
- 2015-03-13 FI FIEP15761889.3T patent/FI3117012T4/fi active
- 2015-03-13 HR HRP20190759TT patent/HRP20190759T4/hr unknown
- 2015-03-13 CN CN202110825684.9A patent/CN113528645A/zh active Pending
- 2015-03-13 AU AU2015229083A patent/AU2015229083B2/en active Active
- 2015-03-13 WO PCT/US2015/020603 patent/WO2015138997A1/en not_active Ceased
- 2015-03-13 US US14/658,061 patent/US11767559B2/en active Active
- 2015-03-13 EP EP15761889.3A patent/EP3117012B2/en active Active
- 2015-03-13 DK DK15761889.3T patent/DK3117012T4/da active
- 2015-03-13 ES ES15761889T patent/ES2726650T5/es active Active
- 2015-03-13 CN CN201580024879.6A patent/CN106536752B/zh active Active
- 2015-03-13 CA CA2970916A patent/CA2970916C/en active Active
- 2015-03-13 HU HUE15761889A patent/HUE043288T2/hu unknown
- 2015-03-13 BR BR112016021038-7A patent/BR112016021038B1/pt active IP Right Grant
- 2015-03-13 PT PT15761889T patent/PT3117012T/pt unknown
- 2015-03-13 TR TR2019/07106T patent/TR201907106T4/tr unknown
- 2015-03-13 SI SI201530724T patent/SI3117012T2/sl unknown
-
2021
- 2021-06-29 AU AU2021204489A patent/AU2021204489B2/en active Active
-
2023
- 2023-07-27 AU AU2023208145A patent/AU2023208145B2/en active Active
- 2023-08-24 US US18/455,527 patent/US20230399696A1/en not_active Abandoned
- 2023-08-24 US US18/455,517 patent/US20230407395A1/en not_active Abandoned
- 2023-08-24 US US18/455,462 patent/US20230399694A1/en not_active Abandoned
- 2023-08-24 US US18/455,499 patent/US20230407394A1/en not_active Abandoned
- 2023-08-24 US US18/455,488 patent/US20230399695A1/en not_active Abandoned
- 2023-08-24 US US18/455,456 patent/US20230407392A1/en not_active Abandoned
- 2023-08-24 US US18/455,537 patent/US20230407396A1/en not_active Abandoned
- 2023-08-24 US US18/455,480 patent/US20230407393A1/en not_active Abandoned
-
2024
- 2024-11-04 US US18/936,839 patent/US12404547B1/en active Active
-
2025
- 2025-07-25 US US19/281,431 patent/US12644153B2/en active Active
-
2026
- 2026-01-07 US US19/442,453 patent/US20260132462A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL276593B (en) | Improved methods for producing adoptive cell therapies | |
| HUE043288T2 (hu) | Eljárások immunszuppresszív terápiák monitorozására transzplantátum recipiensben | |
| ZA201700241B (en) | Mnk inhibitors and methods related thereto | |
| IL251045B (en) | Macropinocytosing human anti-cd46 antibodies and targeted cancer therapeutics | |
| PL3348156T3 (pl) | System e-papierosa i metoda | |
| SI3172567T1 (sl) | Postopki in kompleti za nadzor membranske nefropatije | |
| EP3191826C0 (en) | SYSTEM AND METHOD FOR MEASURING DENSITY | |
| IL249384A0 (en) | Methods for producing cells using perfusate and their use | |
| EP2998732C0 (en) | ANALYSIS PROCESS | |
| IL247840B (en) | Sildenafil solutions and methods for their preparation and use | |
| GB201417372D0 (en) | Methods and kits | |
| PL2908560T3 (pl) | Sposób i układ odwzorowania | |
| IL233451A0 (en) | Charging system and method | |
| TH1501007310A (th) | ภาชนะเพาะเลี้ยงและวิธีเพาะเลี้ยง | |
| TH1501006896A (th) | อุปกรณ์และวิธีการพิสูจน์ตัวจริงด้วยตนเอง | |
| TH1601002248A (th) | องค์ประกอบฆ่าศัตรูพืชและสัตว์และวิธีที่เกี่ยวข้อง | |
| TH1601002244A (th) | องค์ประกอบฆ่าศัตรูพืชและสัตว์และวิธีที่เกี่ยวข้อง | |
| TH1601002246A (th) | องค์ประกอบฆ่าศัตรูพืชและสัตว์และวิธีที่เกี่ยวข้อง | |
| TH1601000720A (th) | วิธีการและระบบสำหรับตรวจสังเกตการนำส่ง | |
| GB201415151D0 (en) | Photoacoustic cell system and method |