DK3117012T3 - Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager - Google Patents
Fremgangsmåder til overvågning af immunosuppressive terapier hos en transplantmodtager Download PDFInfo
- Publication number
- DK3117012T3 DK3117012T3 DK15761889.3T DK15761889T DK3117012T3 DK 3117012 T3 DK3117012 T3 DK 3117012T3 DK 15761889 T DK15761889 T DK 15761889T DK 3117012 T3 DK3117012 T3 DK 3117012T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- transplant recipient
- immunosuppressive therapies
- monitoring
- monitoring immunosuppressive
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953582P | 2014-03-14 | 2014-03-14 | |
| PCT/US2015/020603 WO2015138997A1 (en) | 2014-03-14 | 2015-03-13 | Methods of monitoring immunosuppressive therapies in a transplant recipient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3117012T3 true DK3117012T3 (da) | 2019-05-13 |
| DK3117012T4 DK3117012T4 (da) | 2026-02-09 |
Family
ID=54072508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15761889.3T DK3117012T4 (da) | 2014-03-14 | 2015-03-13 | Fremgangsmåder til overvågning af immunsuppressive behandlinger hos en transplantationsmodtager |
Country Status (16)
| Country | Link |
|---|---|
| US (11) | US11767559B2 (da) |
| EP (1) | EP3117012B2 (da) |
| CN (2) | CN113528645A (da) |
| AU (3) | AU2015229083B2 (da) |
| BR (1) | BR112016021038B1 (da) |
| CA (1) | CA2970916C (da) |
| DK (1) | DK3117012T4 (da) |
| ES (1) | ES2726650T5 (da) |
| FI (1) | FI3117012T4 (da) |
| HR (1) | HRP20190759T1 (da) |
| HU (1) | HUE043288T2 (da) |
| PL (1) | PL3117012T5 (da) |
| PT (1) | PT3117012T (da) |
| SI (1) | SI3117012T1 (da) |
| TR (1) | TR201907106T4 (da) |
| WO (1) | WO2015138997A1 (da) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20120185176A1 (en) | 2009-09-30 | 2012-07-19 | Natera, Inc. | Methods for Non-Invasive Prenatal Ploidy Calling |
| EP2572003A4 (en) | 2010-05-18 | 2016-01-13 | Natera Inc | METHOD FOR NONINVASIVE PRANATAL PLOIDIE ASSIGNMENT |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190284623A1 (en) * | 2010-05-18 | 2019-09-19 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) * | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11332785B2 (en) * | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| WO2012088456A2 (en) | 2010-12-22 | 2012-06-28 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| DK3004388T4 (da) | 2013-05-29 | 2023-08-28 | Chronix Biomedical | Påvisning og kvantificering af cellefrit dna fra donor i kredsløbet hos organtransplantatmodtagere |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| CA2970916C (en) | 2014-03-14 | 2025-02-04 | Caredx, Inc. | METHODS FOR MONITORING IMMUNOSUPPRESSIVE THERAPIES IN A TRANSPLANT RECIPIENT |
| EP3957749A1 (en) | 2014-04-21 | 2022-02-23 | Natera, Inc. | Detecting tumour specific mutations in biopsies with whole exome sequencing and in cell-free samples |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| EP3164503B1 (en) | 2014-07-03 | 2024-08-28 | Agilent Technologies, Inc. | Methods for non-invasive detection of transplant health or rejection |
| WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| CN106544407B (zh) * | 2015-09-18 | 2019-11-08 | 广州华大基因医学检验所有限公司 | 确定受体cfDNA样本中供体来源cfDNA比例的方法 |
| CN105483123B (zh) * | 2015-11-23 | 2019-02-22 | 元码基因科技(北京)股份有限公司 | 遗传标记组合、个体基因身份证及其用途 |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| US11485996B2 (en) | 2016-10-04 | 2022-11-01 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| CN110114477A (zh) * | 2016-11-02 | 2019-08-09 | 威斯康星州立大学医学院 | 用于使用总的和特异性无细胞dna评估风险的方法 |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| CN106520982B (zh) * | 2016-12-05 | 2019-11-08 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种用于身份鉴定的复合分型系统 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| CN107058562B (zh) * | 2017-05-17 | 2018-04-10 | 成都仕康美生物科技有限公司 | Snp位点的应用及其检测试剂盒 |
| AU2018288832B2 (en) | 2017-06-20 | 2025-03-06 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free DNA |
| CA3067635A1 (en) * | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| JP2021506342A (ja) | 2017-12-14 | 2021-02-22 | ティーエーアイ ダイアグノスティックス インコーポレイテッドTai Diagnostics,Inc. | 移植のための移植片適合性の評価 |
| SG11202005474RA (en) * | 2017-12-15 | 2020-07-29 | Acrannolife Genomics Pvt Ltd | A non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| CN107937571B (zh) * | 2018-01-16 | 2021-12-07 | 良培基因生物科技(武汉)有限公司 | 一种基于信息snp集及其引物的核酸质谱亲权鉴定方法 |
| EP3517629A1 (en) | 2018-01-30 | 2019-07-31 | Myway Genetics S.r.L. | Use of cfdna fragments as biomarkers in patients after organ transplantation |
| US12398389B2 (en) | 2018-02-15 | 2025-08-26 | Natera, Inc. | Methods for isolating nucleic acids with size selection |
| CA3090426A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| WO2020010255A1 (en) * | 2018-07-03 | 2020-01-09 | Natera, Inc. | Methods for detection of donor-derived cell-free dna |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| US20210301342A1 (en) * | 2018-09-07 | 2021-09-30 | Sequenom, Inc. | Methods, and systems to detect transplant rejection |
| US20200109449A1 (en) * | 2018-10-09 | 2020-04-09 | Tai Diagnostics, Inc. | Cell lysis assay for cell-free dna analysis |
| US20220073989A1 (en) * | 2018-12-20 | 2022-03-10 | The Regents Of The University Of California | Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA |
| EP3927845A1 (en) * | 2019-02-19 | 2021-12-29 | Sequenom, Inc. | Compositions, methods, and systems to detect hematopoietic stem cell transplantation status |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| EP3980559A1 (en) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| EP4106872A4 (en) * | 2020-03-06 | 2024-04-10 | Denovo Biopharma LLC | Compositions and methods for assessing the efficacy of inhibitors of neurotransmitter transporters |
| EP4168586A1 (en) * | 2020-06-19 | 2023-04-26 | CareDx, Inc. | Methods for monitoring allogeneic cells |
| CN113061666A (zh) * | 2020-12-30 | 2021-07-02 | 中南大学湘雅二医院 | 肝移植后巨细胞病毒的检测方法、应用及系统 |
| WO2022232609A1 (en) * | 2021-04-30 | 2022-11-03 | Caredx, Inc. | Methods for detecting, monitoring, and guiding treatment of allograft rejection using discriminating gene expression signatures |
| EP4373961A4 (en) * | 2021-07-23 | 2025-08-06 | Univ Georgetown | USE OF GENETIC AND EPIGENETIC MARKERS TO DETECT CELL DEATH |
| US20230338419A1 (en) * | 2022-03-21 | 2023-10-26 | The Trustees Of The University Of Pennsylvania | Methods and apparatus for diagnosis and detection of cardiac allograft vasculopathy |
| AU2023237885A1 (en) * | 2022-03-21 | 2024-09-12 | Caredx, Inc. | Methods for non-invasively monitoring organ health in cross-species transplantation |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6401267B1 (en) | 1993-09-27 | 2002-06-11 | Radoje Drmanac | Methods and compositions for efficient nucleic acid sequencing |
| USRE39920E1 (en) * | 1997-05-30 | 2007-11-13 | Xenomics, Inc. | Methods for detection of nucleic acid sequences in urine |
| US6132997A (en) | 1999-05-28 | 2000-10-17 | Agilent Technologies | Method for linear mRNA amplification |
| US7403972B1 (en) | 2002-04-24 | 2008-07-22 | Ip Venture, Inc. | Method and system for enhanced messaging |
| EP1377686A4 (en) | 2001-04-12 | 2007-07-25 | Caliper Life Sciences Inc | SYSTEMS AND METHOD FOR GENETIC ANALYSIS WITH HIGH THROUGHPUT |
| US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
| WO2005035725A2 (en) | 2003-10-08 | 2005-04-21 | The Trustees Of Boston University | Methods for prenatal diagnosis of chromosomal abnormalities |
| US7149658B2 (en) | 2004-02-02 | 2006-12-12 | United Parcel Service Of America, Inc. | Systems and methods for transporting a product using an environmental sensor |
| US20060228721A1 (en) | 2005-04-12 | 2006-10-12 | Leamon John H | Methods for determining sequence variants using ultra-deep sequencing |
| EP2007909A4 (en) | 2006-04-07 | 2011-01-26 | Xdx Inc | EXPRESSION OF NUCLEIC ACID IN RESPONSE TO STEROIDS AND PREDICTION OF DISEASE ACTIVITY |
| US9370689B2 (en) | 2008-01-07 | 2016-06-21 | The Quantum Group, Inc. | System and methods for providing dynamic integrated wellness assessment |
| ES2595489T3 (es) | 2008-07-18 | 2016-12-30 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
| CN104195227B (zh) * | 2008-11-07 | 2017-04-12 | 适应生物技术公司 | 通过序列分析监测状况的方法 |
| HUE052213T2 (hu) * | 2009-11-06 | 2021-04-28 | Univ Leland Stanford Junior | Grafitkilökõdés nem invazív diagnosztizálása szervátültetett betegekben |
| US20110173023A1 (en) | 2010-01-12 | 2011-07-14 | Gryphes Inc. | Method and System for Managing Organ Transplant Transporation |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
| US20180344215A1 (en) | 2015-11-24 | 2018-12-06 | Dacadoo Ag | Automated health data acquisition, processing and communication system and method |
| US10131947B2 (en) * | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
| CN102618626B (zh) * | 2011-01-30 | 2014-05-14 | 杭州优思达生物技术有限公司 | 一种快速单核苷酸多态性的检测方法及试剂盒 |
| US20130024127A1 (en) | 2011-07-19 | 2013-01-24 | John Stuelpnagel | Determination of source contributions using binomial probability calculations |
| EP2758538B1 (en) * | 2011-09-22 | 2018-10-31 | Lineage Biosciences, Inc. | Methods for analyzing heterogeneous samples |
| WO2013049892A1 (en) | 2011-10-07 | 2013-04-11 | Murdoch Childrens Research Institute | Diagnostic assay for tissue transplantation status |
| US8977373B2 (en) | 2011-12-28 | 2015-03-10 | Caterpillar Inc. | Systems and methods for extending physical sensor range using virtual sensors |
| CN103374518B (zh) * | 2012-04-12 | 2018-03-27 | 维里纳塔健康公司 | 拷贝数变异的检测和分类 |
| AU2013249012B2 (en) | 2012-04-19 | 2019-03-28 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| US20150154352A1 (en) | 2012-06-21 | 2015-06-04 | Gigagen, Inc. | System and Methods for Genetic Analysis of Mixed Cell Populations |
| US20150203916A1 (en) | 2012-06-27 | 2015-07-23 | Music Foundation For Research Development | Plasma analytes predict diagnosis and prognosis of thoracic aortic aneurysm |
| US20140088995A1 (en) | 2012-09-21 | 2014-03-27 | Md Revolution, Inc. | Systems and methods for dynamic adjustments for personalized health and wellness programs |
| WO2014074501A1 (en) | 2012-11-06 | 2014-05-15 | Quest Diagnostics Investments Incorporated | Molecular markers for diagnosis of acute cellular rejection and acute tubular necrosis |
| WO2014116729A2 (en) | 2013-01-22 | 2014-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Haplotying of hla loci with ultra-deep shotgun sequencing |
| DK3004388T4 (da) | 2013-05-29 | 2023-08-28 | Chronix Biomedical | Påvisning og kvantificering af cellefrit dna fra donor i kredsløbet hos organtransplantatmodtagere |
| WO2015069933A1 (en) | 2013-11-06 | 2015-05-14 | The Board Of Trustees Of The Leland Stanford Junior University | Circulating cell-free dna for diagnosis of transplant rejection |
| US9982301B2 (en) | 2014-01-07 | 2018-05-29 | Cornell University | Urine mRNA profile and acute dysfunction of kidney allograft |
| CA2970916C (en) * | 2014-03-14 | 2025-02-04 | Caredx, Inc. | METHODS FOR MONITORING IMMUNOSUPPRESSIVE THERAPIES IN A TRANSPLANT RECIPIENT |
| CA2956925C (en) | 2014-08-01 | 2024-02-13 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
| US9648446B2 (en) | 2015-09-22 | 2017-05-09 | Veniam, Inc. | Systems and methods for shipping management in a network of moving things |
| WO2018000031A1 (en) | 2016-06-27 | 2018-01-04 | Olivia Newton-John Cancer Research Institute | Use of cell free dna as a measure of organ health following transplantation |
| US10602964B2 (en) | 2016-08-17 | 2020-03-31 | Koninklijke Philips N.V. | Location, activity, and health compliance monitoring using multidimensional context analysis |
| CN110352251A (zh) * | 2017-03-08 | 2019-10-18 | 豪夫迈·罗氏有限公司 | 引物延伸靶标富集及对其的包括同时富集dna和rna的改进 |
| JP2020515278A (ja) | 2017-04-04 | 2020-05-28 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ドナー遺伝子型の非存在下での移植由来循環セルフリーdnaの定量化 |
| JP7009518B2 (ja) | 2017-06-20 | 2022-01-25 | イルミナ インコーポレイテッド | 既知又は未知の遺伝子型の複数のコントリビューターからのdna混合物の分解及び定量化のための方法並びにシステム |
| IL271147B2 (en) | 2017-06-20 | 2025-04-01 | Illumina Inc | Accurate computational methods for decomposing mixtures of DNA from donors with unknown genotypes |
| SG11202005474RA (en) | 2017-12-15 | 2020-07-29 | Acrannolife Genomics Pvt Ltd | A non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| US11961033B2 (en) | 2018-01-05 | 2024-04-16 | Convey, Llc | System and method for dynamically scheduling API-based shipment updates across carriers |
| MX2020007666A (es) | 2018-01-19 | 2020-10-14 | Univ Maryland | Técnicas para la manipulación de órganos humanos durante el transporte. |
| CN112118781B (zh) | 2018-03-12 | 2026-02-27 | 加利福尼亚大学董事会 | 通过t细胞受体亚基库多样性的分析评估移植排斥状态 |
| EP3790987A4 (en) | 2018-05-10 | 2022-01-19 | The Scripps Research Institute | GENOME-WIDE CLASSIFIERS FOR THE DETECTION OF SUBACUTE TRANSPLANT REJECTION AND OTHER TRANSPLANT CONDITIONS |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020010255A1 (en) * | 2018-07-03 | 2020-01-09 | Natera, Inc. | Methods for detection of donor-derived cell-free dna |
| US10402774B1 (en) | 2018-07-25 | 2019-09-03 | Capital One Services, LLP | Intelligence platform for automated retrieval or protection of a package or a person by an unmanned vehicle (UV) |
| US20210301342A1 (en) * | 2018-09-07 | 2021-09-30 | Sequenom, Inc. | Methods, and systems to detect transplant rejection |
| US20220073989A1 (en) * | 2018-12-20 | 2022-03-10 | The Regents Of The University Of California | Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA |
| EP3927845A1 (en) | 2019-02-19 | 2021-12-29 | Sequenom, Inc. | Compositions, methods, and systems to detect hematopoietic stem cell transplantation status |
| EP3712898A1 (en) | 2019-03-21 | 2020-09-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method of predicting whether a kidney transplant recipient is at risk of having allograft loss |
| WO2021021657A1 (en) | 2019-07-29 | 2021-02-04 | University Of Miami | System and method for ai-based eye condition determinations |
| WO2021092476A1 (en) | 2019-11-06 | 2021-05-14 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for analyzing nucleic acid molecules |
| EP4168586A1 (en) | 2020-06-19 | 2023-04-26 | CareDx, Inc. | Methods for monitoring allogeneic cells |
| WO2022035519A1 (en) | 2020-08-14 | 2022-02-17 | Caredx, Inc. | A system and methods for determining scores indicative of a transplant recipient's activities and behaviors |
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2015
- 2015-03-13 CA CA2970916A patent/CA2970916C/en active Active
- 2015-03-13 PL PL15761889.3T patent/PL3117012T5/pl unknown
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