PL3126376T3 - Pochodne polimyksyn jako związki przeciwdrobnoustrojowe - Google Patents
Pochodne polimyksyn jako związki przeciwdrobnoustrojoweInfo
- Publication number
- PL3126376T3 PL3126376T3 PL15772554.0T PL15772554T PL3126376T3 PL 3126376 T3 PL3126376 T3 PL 3126376T3 PL 15772554 T PL15772554 T PL 15772554T PL 3126376 T3 PL3126376 T3 PL 3126376T3
- Authority
- PL
- Poland
- Prior art keywords
- antimicrobial compounds
- polymyxin derivatives
- polymyxin
- derivatives
- antimicrobial
- Prior art date
Links
- 108010040201 Polymyxins Proteins 0.000 title 1
- 230000000845 anti-microbial effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2014901182A AU2014901182A0 (en) | 2014-04-01 | Antimicrobial compounds | |
| PCT/AU2015/050149 WO2015149131A1 (en) | 2014-04-01 | 2015-04-01 | Polymyxin derivatives as antimicrobial compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3126376T3 true PL3126376T3 (pl) | 2024-10-28 |
Family
ID=54239144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15772554.0T PL3126376T3 (pl) | 2014-04-01 | 2015-04-01 | Pochodne polimyksyn jako związki przeciwdrobnoustrojowe |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10047126B2 (pl) |
| EP (2) | EP3126376B1 (pl) |
| JP (3) | JP2017512818A (pl) |
| CN (1) | CN106414480B (pl) |
| AU (1) | AU2015240435B2 (pl) |
| CA (1) | CA2944550C (pl) |
| ES (1) | ES2999407T3 (pl) |
| HU (1) | HUE068512T2 (pl) |
| NZ (1) | NZ724798A (pl) |
| PL (1) | PL3126376T3 (pl) |
| WO (1) | WO2015149131A1 (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE059544T2 (hu) | 2013-05-22 | 2022-11-28 | Spero Therapeutics Inc | Polimixin-származékok és ezek alkalmazása kombinációs terápiában különbözõ antibiotikumokkal |
| CN107108699A (zh) * | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| EP3233889B1 (en) | 2014-12-16 | 2022-07-06 | Shanghai MicuRx Pharmaceutical Co., Ltd. | Antimicrobial polymyxins for treatment of bacterial infections |
| JP7367950B2 (ja) * | 2015-09-29 | 2023-10-24 | モナッシュ ユニバーシティ | 抗菌性ポリミキシン誘導体化合物 |
| US20190315806A1 (en) * | 2016-12-16 | 2019-10-17 | Institute Of Medicinal Biotechnology, Chinese Academy Of Medical Sciences | Polymyxin derivative, preparation method and application thereof |
| GB201703898D0 (en) * | 2017-03-10 | 2017-04-26 | Helperby Therapeautics Ltd | Method |
| WO2019084628A1 (en) | 2017-11-02 | 2019-05-09 | The University Of Queensland | Peptide antibiotics |
| DK3810633T3 (da) | 2018-06-25 | 2024-01-15 | Spero Therapeutics Inc | Forbindelser |
| US11752175B2 (en) | 2018-09-21 | 2023-09-12 | Cornell University | Compositions and methods for glaucoma |
| CN110845579B (zh) * | 2019-08-08 | 2022-04-19 | 上海市食品药品检验研究院 | 一种多黏菌素e组分及其光化学产物和液相色谱-质谱分析方法 |
| WO2021150792A1 (en) | 2020-01-21 | 2021-07-29 | Micurx Pharmaceuticals, Inc. | Novel compounds and composition for targeted therapy of kidney-associated cancers |
| CN115996742A (zh) * | 2020-03-25 | 2023-04-21 | 奥夫博医疗创新有限公司 | 用于青光眼的方法和药剂 |
| TW202233649A (zh) * | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| WO2022206826A1 (zh) * | 2021-03-31 | 2022-10-06 | 江苏奥赛康药业有限公司 | 一种多粘菌素衍生物的硫酸盐及其药物组合物 |
| KR20250037611A (ko) * | 2023-09-07 | 2025-03-18 | 웰펩 주식회사 | 그람 음성균 및 다제내성 그람 음성균에 우수한 항균 활성을 갖는 신규 폴리믹신 유사체, 이를 포함하는 항균용 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| WO2006045156A1 (en) * | 2004-10-29 | 2006-05-04 | Monash University | Therapy for multi-drug resistant microorganisms |
| KR100750658B1 (ko) * | 2005-12-09 | 2007-08-20 | 한국생명공학연구원 | 폴리믹신 생합성 효소 및 이를 코딩하는 유전자 군 |
| US8329645B2 (en) * | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| WO2010075416A1 (en) | 2008-12-23 | 2010-07-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2010130007A1 (en) | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| MX355217B (es) | 2011-11-18 | 2018-04-10 | New Pharma Licence Holdings Ltd | Derivados de polimixina. |
| KR20160135739A (ko) | 2014-03-11 | 2016-11-28 | 뉴 파마 라이센스 홀딩스 리미티드 | 폴리믹신 유도체 및 상이한 항생제와의 조합 요법에 있어서의 이들의 용도 |
| JP7367950B2 (ja) | 2015-09-29 | 2023-10-24 | モナッシュ ユニバーシティ | 抗菌性ポリミキシン誘導体化合物 |
-
2015
- 2015-04-01 US US15/301,310 patent/US10047126B2/en not_active Ceased
- 2015-04-01 AU AU2015240435A patent/AU2015240435B2/en active Active
- 2015-04-01 PL PL15772554.0T patent/PL3126376T3/pl unknown
- 2015-04-01 HU HUE15772554A patent/HUE068512T2/hu unknown
- 2015-04-01 CN CN201580027296.9A patent/CN106414480B/zh active Active
- 2015-04-01 JP JP2016560550A patent/JP2017512818A/ja active Pending
- 2015-04-01 NZ NZ724798A patent/NZ724798A/en unknown
- 2015-04-01 US US16/144,967 patent/USRE48335E1/en active Active
- 2015-04-01 WO PCT/AU2015/050149 patent/WO2015149131A1/en not_active Ceased
- 2015-04-01 CA CA2944550A patent/CA2944550C/en active Active
- 2015-04-01 EP EP15772554.0A patent/EP3126376B1/en active Active
- 2015-04-01 EP EP24195419.7A patent/EP4477272A3/en active Pending
- 2015-04-01 ES ES15772554T patent/ES2999407T3/es active Active
-
2019
- 2019-03-15 JP JP2019049103A patent/JP2019108396A/ja active Pending
-
2020
- 2020-06-10 JP JP2020101282A patent/JP7117021B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015149131A1 (en) | 2015-10-08 |
| CN106414480A (zh) | 2017-02-15 |
| JP2020169184A (ja) | 2020-10-15 |
| EP4477272A3 (en) | 2025-03-12 |
| CA2944550C (en) | 2021-05-25 |
| USRE48335E1 (en) | 2020-12-01 |
| AU2015240435B2 (en) | 2019-09-19 |
| HUE068512T2 (hu) | 2024-12-28 |
| JP2019108396A (ja) | 2019-07-04 |
| CA2944550A1 (en) | 2015-10-08 |
| ES2999407T3 (en) | 2025-02-25 |
| EP3126376A4 (en) | 2017-10-25 |
| EP3126376B1 (en) | 2024-08-21 |
| CN106414480B (zh) | 2020-08-04 |
| AU2015240435A1 (en) | 2016-10-20 |
| NZ724798A (en) | 2020-05-29 |
| US20170137469A1 (en) | 2017-05-18 |
| US10047126B2 (en) | 2018-08-14 |
| JP7117021B2 (ja) | 2022-08-12 |
| EP3126376C0 (en) | 2024-08-21 |
| EP4477272A2 (en) | 2024-12-18 |
| JP2017512818A (ja) | 2017-05-25 |
| EP3126376A1 (en) | 2017-02-08 |
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