PL3164492T3 - Układy ekspresji polipeptydu - Google Patents

Układy ekspresji polipeptydu

Info

Publication number
PL3164492T3
PL3164492T3 PL15739141T PL15739141T PL3164492T3 PL 3164492 T3 PL3164492 T3 PL 3164492T3 PL 15739141 T PL15739141 T PL 15739141T PL 15739141 T PL15739141 T PL 15739141T PL 3164492 T3 PL3164492 T3 PL 3164492T3
Authority
PL
Poland
Prior art keywords
expression systems
polypeptide expression
polypeptide
systems
expression
Prior art date
Application number
PL15739141T
Other languages
English (en)
Inventor
Isidro Hotzel
Yonglei Shang
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3164492T3 publication Critical patent/PL3164492T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PL15739141T 2014-07-03 2015-07-02 Układy ekspresji polipeptydu PL3164492T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462020838P 2014-07-03 2014-07-03
US201462080698P 2014-11-17 2014-11-17
PCT/US2015/039086 WO2016004370A1 (en) 2014-07-03 2015-07-02 Polypeptide expression systems
EP15739141.8A EP3164492B1 (en) 2014-07-03 2015-07-02 Polypeptide expression systems

Publications (1)

Publication Number Publication Date
PL3164492T3 true PL3164492T3 (pl) 2020-04-30

Family

ID=53674343

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15739141T PL3164492T3 (pl) 2014-07-03 2015-07-02 Układy ekspresji polipeptydu

Country Status (9)

Country Link
US (2) US10308944B2 (pl)
EP (2) EP3164492B1 (pl)
JP (5) JP6694400B2 (pl)
CN (2) CN113789339A (pl)
ES (1) ES2763526T3 (pl)
HR (1) HRP20192243T1 (pl)
PL (1) PL3164492T3 (pl)
SI (1) SI3164492T1 (pl)
WO (1) WO2016004370A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9803191B2 (en) * 2012-07-05 2017-10-31 Genentech, Inc. Expression and secretion system
ES2763526T3 (es) * 2014-07-03 2020-05-29 Hoffmann La Roche Sistemas de expresión de polipéptidos
WO2020205604A1 (en) 2019-03-29 2020-10-08 Salk Institute For Biological Studies High-efficiency reconstitution of rna molecules
JP2022538598A (ja) * 2019-06-25 2022-09-05 ミガル ガリラヤ リサーチ インスティテュート リミテッド プレｍＲＮＡのトランススプライシングに基づく合成転写用論理「ＡＮＤ」ゲートを作製するためのシステムおよびその使用
IL292904A (en) * 2019-11-11 2022-07-01 Salk Inst For Biological Studi Compositions and methods for high-efficiency recombination of rna molecules
JP7643841B2 (ja) 2020-07-01 2025-03-11 カヤバ株式会社 リリーフ弁

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EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
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US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
ATE354957T1 (de) 1995-12-15 2006-03-15 Intronn Inc Durch trans-spaltung erhaltene therapeutische molekule
US20030027250A1 (en) * 1995-12-15 2003-02-06 Mitchell Lloyd G. Methods and compositions for use in spliceosome mediated RNA trans-splicing
US20020062010A1 (en) 1997-05-02 2002-05-23 Genentech, Inc. Method for making multispecific antibodies having heteromultimeric and common components
DK1034298T3 (da) 1997-12-05 2012-01-30 Scripps Research Inst Humanisering af murint antistof
JP2003531588A (ja) 2000-04-11 2003-10-28 ジェネンテック・インコーポレーテッド 多価抗体とその用途
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KR100465201B1 (ko) * 2002-07-16 2005-01-13 현대모비스 주식회사 안티로크 브레이크 시스템의 액압 제어용 전자식 밸브
EP1588166A4 (en) 2003-01-09 2007-06-27 Macrogenics Inc VECTOR SYSTEM WITH DOUBLE EXPRESSION FOR EXPRESSING ANTIBODIES IN BACTERIAL AND MAMMAL CELLS
EP1740615B1 (en) 2004-03-31 2014-11-05 Genentech, Inc. Humanized anti-tgf-beta antibodies
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US7807409B2 (en) * 2005-10-21 2010-10-05 Roche Palo Alto Llc Method for the recombinant expression of a polypeptide
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー／エス 二重特異性抗体の生産
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JP6157046B2 (ja) 2008-01-07 2017-07-05 アムジェン インコーポレイテッド 静電的ステアリング（ｅｌｅｃｔｒｏｓｔａｔｉｃｓｔｅｅｒｉｎｇ）効果を用いた抗体Ｆｃヘテロ二量体分子を作製するための方法
JP2012503982A (ja) * 2008-09-26 2012-02-16 ワイス・エルエルシー 適合性ディスプレイベクター系
EP2478013B1 (en) 2009-09-16 2018-10-24 F.Hoffmann-La Roche Ag Coiled coil and/or tether containing protein complexes and uses thereof
ES2829199T3 (es) * 2010-11-22 2021-05-31 Amicus Therapeutics Inc Nuevas secuencias de señalización para mejorar la expresión y segregación de proteínas de enzimas recombinantes y otras proteínas
US9803191B2 (en) * 2012-07-05 2017-10-31 Genentech, Inc. Expression and secretion system
ES2763526T3 (es) * 2014-07-03 2020-05-29 Hoffmann La Roche Sistemas de expresión de polipéptidos

Also Published As

Publication number Publication date
WO2016004370A1 (en) 2016-01-07
US20190256859A1 (en) 2019-08-22
EP3164492B1 (en) 2019-10-23
HRP20192243T1 (hr) 2020-03-06
CN113789339A (zh) 2021-12-14
JP2025097990A (ja) 2025-07-01
CN106574270A (zh) 2017-04-19
JP2025118659A (ja) 2025-08-13
JP2020114219A (ja) 2020-07-30
US11851661B2 (en) 2023-12-26
ES2763526T3 (es) 2020-05-29
CN106574270B (zh) 2021-07-13
EP3680336A1 (en) 2020-07-15
US10308944B2 (en) 2019-06-04
EP3164492A1 (en) 2017-05-10
US20160002642A1 (en) 2016-01-07
SI3164492T1 (sl) 2020-02-28
JP2023081910A (ja) 2023-06-13
JP2017520255A (ja) 2017-07-27
JP6694400B2 (ja) 2020-05-13

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