PL3194592T3 - Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy - Google Patents

Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy

Info

Publication number
PL3194592T3
PL3194592T3 PL15741963T PL15741963T PL3194592T3 PL 3194592 T3 PL3194592 T3 PL 3194592T3 PL 15741963 T PL15741963 T PL 15741963T PL 15741963 T PL15741963 T PL 15741963T PL 3194592 T3 PL3194592 T3 PL 3194592T3
Authority
PL
Poland
Prior art keywords
lactic acid
genetically modified
acid producing
thermophilic bacteria
producing thermophilic
Prior art date
Application number
PL15741963T
Other languages
English (en)
Inventor
Marinus Petrus Machielsen
Mariska Van Hartskamp
Richard Van Kranenburg
Original Assignee
Purac Biochem Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem Bv filed Critical Purac Biochem Bv
Publication of PL3194592T3 publication Critical patent/PL3194592T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028—D-Lactate dehydrogenase (1.1.1.28)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01054—Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03003—Methylglyoxal synthase (4.2.3.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL15741963T 2014-07-23 2015-07-13 Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy PL3194592T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14178144 2014-07-23
PCT/EP2015/065990 WO2016012296A1 (en) 2014-07-23 2015-07-13 Genetically modified (r)-lactic acid producing thermophilic bacteria
EP15741963.1A EP3194592B1 (en) 2014-07-23 2015-07-13 Genetically modified (r)-lactic acid producing thermophilic bacteria

Publications (1)

Publication Number Publication Date
PL3194592T3 true PL3194592T3 (pl) 2021-02-08

Family

ID=51211697

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15741963T PL3194592T3 (pl) 2014-07-23 2015-07-13 Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy

Country Status (12)

Country Link
US (1) US10731186B2 (pl)
EP (1) EP3194592B1 (pl)
JP (1) JP6637026B2 (pl)
KR (1) KR101980069B1 (pl)
CN (1) CN106574236B (pl)
AU (1) AU2015294136C9 (pl)
BR (1) BR112017000846B1 (pl)
CA (1) CA2955717C (pl)
ES (1) ES2821418T3 (pl)
PL (1) PL3194592T3 (pl)
PT (1) PT3194592T (pl)
WO (1) WO2016012296A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11242513B2 (en) 2016-12-14 2022-02-08 Wageningen Universiteit Thermostable Cas9 nucleases
US20210403928A1 (en) 2018-11-30 2021-12-30 Utilization Of Carbon Dioxide Institute Co., Ltd. Lactic Acid-Producing Hydrogenophilus Bacterium Transformant
EP4012020A4 (en) 2019-08-09 2022-08-17 Utilization of Carbon Dioxide Institute Co.,Ltd. LACTIC ACID-PRODUCING TRANSGENIC HYDROGENOPHILUS BACTERIUM
CN111154705B (zh) * 2020-01-07 2021-06-29 中国科学院微生物研究所 热葡萄糖苷酶地芽孢杆菌工程菌及其构建方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4336082B2 (ja) * 2001-05-29 2009-09-30 花王株式会社 宿主微生物
GB0117551D0 (en) * 2001-07-18 2001-09-12 Elsworth Biotech Ltd Lastic acid production
US9497168B2 (en) 2002-07-30 2016-11-15 Avaya Inc. Method and apparatus for supporting communications between a computing device within a network and an external computing device
KR101185656B1 (ko) 2003-06-18 2012-09-24 디에스엠 아이피 어셋츠 비.브이. 포자를 형성할 수 없는 미생물을 사용한 판토텐산염의 제조방법
US7098009B2 (en) * 2004-03-04 2006-08-29 University Of Florida Research Foundation, Inc. Production of chemicals from lignocellulose, biomass or sugars
ES2401339T3 (es) * 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
WO2007120198A2 (en) 2005-11-08 2007-10-25 University Of Florida Research Foundation, Inc. Materials and methods for improved microbial production of organic compounds
WO2007085443A2 (en) * 2006-01-24 2007-08-02 Purac Biochem Bv Genetic modification of homolactic thermophilic bacilli
BR112013012603A2 (pt) 2010-11-22 2016-08-09 Univ Florida Res Foudation Inc engenharia de bacillus coagulans termotolerante para a produção de ácido d(-)-láctico
KR101438882B1 (ko) 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 d형 젖산 생산균주
WO2014017469A1 (ja) * 2012-07-23 2014-01-30 三井化学株式会社 D-乳酸の生産方法、ポリマーの生産方法およびポリマー

Also Published As

Publication number Publication date
BR112017000846A2 (pt) 2018-07-31
KR20170019467A (ko) 2017-02-21
PT3194592T (pt) 2020-09-25
JP6637026B2 (ja) 2020-01-29
AU2015294136C9 (en) 2019-05-02
CN106574236B (zh) 2020-12-11
EP3194592A1 (en) 2017-07-26
AU2015294136A1 (en) 2017-02-09
AU2015294136C1 (en) 2018-10-25
US10731186B2 (en) 2020-08-04
US20170275656A1 (en) 2017-09-28
CA2955717A1 (en) 2016-01-28
CN106574236A (zh) 2017-04-19
CA2955717C (en) 2020-09-22
BR112017000846B1 (pt) 2024-01-16
EP3194592B1 (en) 2020-07-08
ES2821418T3 (es) 2021-04-26
WO2016012296A1 (en) 2016-01-28
AU2015294136B2 (en) 2018-04-26
JP2017523778A (ja) 2017-08-24
KR101980069B1 (ko) 2019-05-20

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