PL3203997T3 - Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów - Google Patents

Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów

Info

Publication number: PL3203997T3
Authority: PL; Poland
Prior art keywords: clothes; prevention; treatment; pathological conditions; valproic acid
Prior art date: 2014-10-08

Application number

PL15790632T

Other languages

English (en)

Inventor

Sverker JERN

Jonas Faijerson SÄLJÖ

Niklas BERGH

Original Assignee

Cereno Scientific Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-10-08

Filing date

2015-10-08

Publication date

2022-05-16

2015-10-08 Application filed by Cereno Scientific Ab filed Critical Cereno Scientific Ab

2022-05-16 Publication of PL3203997T3 publication Critical patent/PL3203997T3/pl

Links

NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical compound CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title 2
102000009123 Fibrin Human genes 0.000 title 1
108010073385 Fibrin Proteins 0.000 title 1
BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title 1
230000008021 deposition Effects 0.000 title 1
229950003499 fibrin Drugs 0.000 title 1
230000001575 pathological effect Effects 0.000 title 1
230000002265 prevention Effects 0.000 title 1
229960000604 valproic acid Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL15790632T 2014-10-08 2015-10-08 Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów PL3203997T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB1417828.9A GB201417828D0 (en)	2014-10-08	2014-10-08	New methods and compositions
EP15790632.2A EP3203997B1 (en)	2014-10-08	2015-10-08	Valproic acid for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
PCT/GB2015/052950 WO2016055797A2 (en)	2014-10-08	2015-10-08	Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation

Publications (1)

Publication Number	Publication Date
PL3203997T3 true PL3203997T3 (pl)	2022-05-16

Family

ID=51947070

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL15790632T PL3203997T3 (pl)	2014-10-08	2015-10-08	Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów

Country Status (20)

Country	Link
US (4)	US10111845B2 (pl)
EP (2)	EP3203997B1 (pl)
JP (2)	JP6787901B2 (pl)
KR (2)	KR20170063857A (pl)
CN (3)	CN107205975A (pl)
AU (1)	AU2015329795B2 (pl)
BR (1)	BR112017007144A2 (pl)
CA (2)	CA3234641A1 (pl)
CL (1)	CL2017000866A1 (pl)
DK (1)	DK3203997T3 (pl)
ES (1)	ES2913225T3 (pl)
GB (1)	GB201417828D0 (pl)
HU (1)	HUE058316T2 (pl)
IL (1)	IL251142B (pl)
MX (2)	MX2017004558A (pl)
MY (1)	MY192055A (pl)
PL (1)	PL3203997T3 (pl)
RU (1)	RU2732761C2 (pl)
SG (1)	SG11201702058XA (pl)
WO (1)	WO2016055797A2 (pl)

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LT3105218T (lt)	2014-02-13	2019-12-10	Incyte Corp	Ciklopropilaminai kaip lsd1 inhibitoriai
WO2016007731A1 (en)	2014-07-10	2016-01-14	Incyte Corporation	Imidazopyridines and imidazopyrazines as lsd1 inhibitors
WO2016007722A1 (en)	2014-07-10	2016-01-14	Incyte Corporation	Triazolopyridines and triazolopyrazines as lsd1 inhibitors
WO2016007736A1 (en)	2014-07-10	2016-01-14	Incyte Corporation	Imidazopyrazines as lsd1 inhibitors
GB201417828D0 (en)	2014-10-08	2014-11-19	Cereno Scient Ab	New methods and compositions
EA201792205A1 (ru)	2015-04-03	2018-02-28	Инсайт Корпорейшн	Гетероциклические соединения как ингибиторы lsd1
DK3334709T3 (da)	2015-08-12	2025-02-03	Incyte Holdings Corp	Salte af en lsd1-hæmmer
US11395808B2 (en)	2016-04-08	2022-07-26	Cereno Scientific Ab	Delayed release pharmaceutical formulations comprising valproic acid, and uses thereof
WO2017175010A1 (en) *	2016-04-08	2017-10-12	Cereno Scientific Ab	Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
US10968200B2 (en)	2018-08-31	2021-04-06	Incyte Corporation	Salts of an LSD1 inhibitor and processes for preparing the same
US20230069590A1 (en) *	2020-01-16	2023-03-02	The Regents Of The University Of Michigan	Concentrated sodium valproate for rapid delivery
CN111450072B (zh) *	2020-05-07	2022-07-15	江苏艾立康医药科技有限公司	一种替格瑞洛控释片及其制备方法
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WO2026068561A1 (en)	2024-09-24	2026-04-02	Cereno Scientific Ab	Valproic acid for use in treating pulmonary arterial hypertension

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GB201417828D0 (en)	2014-10-08	2014-11-19	Cereno Scient Ab	New methods and compositions
WO2017175010A1 (en)	2016-04-08	2017-10-12	Cereno Scientific Ab	Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
US11395808B2 (en)	2016-04-08	2022-07-26	Cereno Scientific Ab	Delayed release pharmaceutical formulations comprising valproic acid, and uses thereof

2014
- 2014-10-08 GB GBGB1417828.9A patent/GB201417828D0/en not_active Ceased
2015
- 2015-10-08 KR KR1020177011492A patent/KR20170063857A/ko not_active Ceased
- 2015-10-08 US US15/517,229 patent/US10111845B2/en active Active
- 2015-10-08 CN CN201580055071.4A patent/CN107205975A/zh active Pending
- 2015-10-08 EP EP15790632.2A patent/EP3203997B1/en active Active
- 2015-10-08 HU HUE15790632A patent/HUE058316T2/hu unknown
- 2015-10-08 IL IL251142A patent/IL251142B/en unknown
- 2015-10-08 JP JP2017538468A patent/JP6787901B2/ja active Active
- 2015-10-08 EP EP21216908.0A patent/EP4066825A1/en active Pending
- 2015-10-08 MX MX2017004558A patent/MX2017004558A/es unknown
- 2015-10-08 CN CN202211237344.5A patent/CN115721635A/zh active Pending
- 2015-10-08 RU RU2017114933A patent/RU2732761C2/ru active
- 2015-10-08 CA CA3234641A patent/CA3234641A1/en active Pending
- 2015-10-08 ES ES15790632T patent/ES2913225T3/es active Active
- 2015-10-08 MY MYPI2017701203A patent/MY192055A/en unknown
- 2015-10-08 CA CA2964041A patent/CA2964041C/en active Active
- 2015-10-08 AU AU2015329795A patent/AU2015329795B2/en active Active
- 2015-10-08 CN CN202211231367.5A patent/CN115581691A/zh active Pending
- 2015-10-08 DK DK15790632.2T patent/DK3203997T3/da active
- 2015-10-08 WO PCT/GB2015/052950 patent/WO2016055797A2/en not_active Ceased
- 2015-10-08 KR KR1020247041714A patent/KR20250005512A/ko active Pending
- 2015-10-08 SG SG11201702058XA patent/SG11201702058XA/en unknown
- 2015-10-08 PL PL15790632T patent/PL3203997T3/pl unknown
- 2015-10-08 BR BR112017007144A patent/BR112017007144A2/pt not_active Application Discontinuation
2017
- 2017-04-06 MX MX2022007221A patent/MX2022007221A/es unknown
- 2017-04-07 CL CL2017000866A patent/CL2017000866A1/es unknown
2018
- 2018-09-19 US US16/135,639 patent/US11400064B2/en active Active
2020
- 2020-10-29 JP JP2020181522A patent/JP7305605B2/ja active Active
2022
- 2022-08-01 US US17/816,486 patent/US12245999B2/en active Active
2025
- 2025-03-10 US US19/075,243 patent/US20250241880A1/en active Pending

Also Published As

Publication number	Publication date
CA2964041C (en)	2024-04-09
WO2016055797A2 (en)	2016-04-14
CN107205975A (zh)	2017-09-26
CA3234641A1 (en)	2016-04-14
US10111845B2 (en)	2018-10-30
ES2913225T3 (es)	2022-06-01
WO2016055797A3 (en)	2016-06-09
BR112017007144A2 (pt)	2017-12-19
EP4066825A1 (en)	2022-10-05
HUE058316T2 (hu)	2022-07-28
JP6787901B2 (ja)	2020-11-18
GB201417828D0 (en)	2014-11-19
KR20170063857A (ko)	2017-06-08
US11400064B2 (en)	2022-08-02
CA2964041A1 (en)	2016-04-14
AU2015329795A1 (en)	2017-04-13
IL251142A0 (en)	2017-04-30
US20220401393A1 (en)	2022-12-22
US20190015360A1 (en)	2019-01-17
MY192055A (en)	2022-07-25
JP2017532376A (ja)	2017-11-02
MX2022007221A (es)	2022-07-12
CN115581691A (zh)	2023-01-10
RU2017114933A3 (pl)	2019-05-16
MX2017004558A (es)	2017-12-14
IL251142B (en)	2022-07-01
DK3203997T3 (da)	2022-05-23
SG11201702058XA (en)	2017-04-27
CL2017000866A1 (es)	2017-11-24
US12245999B2 (en)	2025-03-11
NZ730307A (en)	2024-01-26
AU2015329795B2 (en)	2021-03-25
RU2017114933A (ru)	2018-11-12
JP7305605B2 (ja)	2023-07-10
JP2021008523A (ja)	2021-01-28
KR20250005512A (ko)	2025-01-09
CN115721635A (zh)	2023-03-03
EP3203997A2 (en)	2017-08-16
US20250241880A1 (en)	2025-07-31
EP3203997B1 (en)	2022-03-02
US20180177751A1 (en)	2018-06-28
RU2732761C2 (ru)	2020-09-22

Publication	Publication Date	Title
EP3695666A4 (en)	2020-11-25	DETECTION OF DRIVING ACTIONS THAT REDUCE THE RISK
IL251142A0 (en)	2017-04-30	Valproic acid for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
EP3261641A4 (en)	2019-05-22	PANKREATITISBEHANDLUNG
LT3334422T (lt)	2020-11-25	Kanabidiolio rūgšties panaudojimas epilepsijos gydymui
EP3370721A4 (en)	2019-05-22	TREATMENT OF OSTEOARTHRITIS
EP4015648C0 (en)	2024-11-13	REDUCTION OF INTRON RETENTION
FR3046933B1 (fr)	2018-03-02	Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires
EP3263132C0 (en)	2023-12-06	COMPOSITION FOR THE TREATMENT OF DISEASES ASSOCIATED WITH IL-6
DK3125875T3 (da)	2023-07-24	Inhalerbar rapamycinformulering til behandling af aldersrelaterede tilstande
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