PL3233832T3 - Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków - Google Patents
Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssakówInfo
- Publication number
- PL3233832T3 PL3233832T3 PL15825641T PL15825641T PL3233832T3 PL 3233832 T3 PL3233832 T3 PL 3233832T3 PL 15825641 T PL15825641 T PL 15825641T PL 15825641 T PL15825641 T PL 15825641T PL 3233832 T3 PL3233832 T3 PL 3233832T3
- Authority
- PL
- Poland
- Prior art keywords
- substituted amino
- mammalian chitinase
- acidic mammalian
- triazoles useful
- amino triazoles
- Prior art date
Links
- JSIAIROWMJGMQZ-UHFFFAOYSA-N 2h-triazol-4-amine Chemical class NC1=CNN=N1 JSIAIROWMJGMQZ-UHFFFAOYSA-N 0.000 title 1
- 102100037839 Acidic mammalian chitinase Human genes 0.000 title 1
- 101710178876 Acidic mammalian chitinase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
- G01N2333/942—Hydrolases (3) acting on glycosyl compounds (3.2) acting on beta-1, 4-glucosidic bonds, e.g. cellulase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
- G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462094446P | 2014-12-19 | 2014-12-19 | |
| US14/959,369 US9440953B2 (en) | 2014-12-19 | 2015-12-04 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors |
| PL415073A PL415073A1 (pl) | 2014-12-19 | 2015-12-04 | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
| EP15825641.2A EP3233832B1 (en) | 2014-12-19 | 2015-12-18 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors |
| PCT/PL2015/050071 WO2016099311A1 (en) | 2014-12-19 | 2015-12-18 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3233832T3 true PL3233832T3 (pl) | 2020-06-29 |
Family
ID=56120793
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL415073A PL415073A1 (pl) | 2014-12-19 | 2015-12-04 | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
| PL15825641T PL3233832T3 (pl) | 2014-12-19 | 2015-12-18 | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL415073A PL415073A1 (pl) | 2014-12-19 | 2015-12-04 | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9440953B2 (pl) |
| EP (1) | EP3233832B1 (pl) |
| CN (1) | CN107428720B (pl) |
| AU (1) | AU2015363761B2 (pl) |
| CA (1) | CA2971395A1 (pl) |
| PL (2) | PL415073A1 (pl) |
| WO (1) | WO2016099311A1 (pl) |
| ZA (1) | ZA201704879B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL415078A1 (pl) * | 2015-09-04 | 2017-03-13 | Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością | Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków |
| MX2022000306A (es) | 2019-07-15 | 2022-03-11 | Oncoarendi Therapeutics Sa | Amino triazoles sustituidos utiles como inhibidores de quitinasa. |
| MX2022002881A (es) | 2019-09-25 | 2022-06-08 | Oncoarendi Therapeutics Sa | Proceso para la produccion de 5-(4-((2s,5s)-5-(4-clorobencil)-2-me tilmorfolino)piperidin-1-il)-1h-1,2,4-triazol-3-amina. |
| US11912647B2 (en) | 2020-05-22 | 2024-02-27 | University Of Georgia Research Foundation, Inc. | Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation |
| CN111732571B (zh) * | 2020-07-24 | 2021-06-29 | 广西壮族自治区农业科学院 | 一种用于防治香蕉枯萎病的杀植物真菌剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4276297A (en) * | 1979-06-18 | 1981-06-30 | Pfizer Inc. | Pyridylaminotriazole therapeutic agents |
| US4421753A (en) * | 1982-01-15 | 1983-12-20 | American Cyanamid Company | 1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines |
| JP3507486B2 (ja) | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| EP3082805B1 (en) | 2013-12-20 | 2020-02-05 | Institute for Drug Discovery, LLC | Substituted amino triazoles, and methods using same |
-
2015
- 2015-12-04 US US14/959,369 patent/US9440953B2/en active Active
- 2015-12-04 PL PL415073A patent/PL415073A1/pl unknown
- 2015-12-18 AU AU2015363761A patent/AU2015363761B2/en active Active
- 2015-12-18 EP EP15825641.2A patent/EP3233832B1/en active Active
- 2015-12-18 WO PCT/PL2015/050071 patent/WO2016099311A1/en not_active Ceased
- 2015-12-18 CN CN201580076502.5A patent/CN107428720B/zh active Active
- 2015-12-18 PL PL15825641T patent/PL3233832T3/pl unknown
- 2015-12-18 CA CA2971395A patent/CA2971395A1/en not_active Abandoned
-
2016
- 2016-09-01 US US15/254,538 patent/US20160368894A1/en not_active Abandoned
-
2017
- 2017-07-18 ZA ZA2017/04879A patent/ZA201704879B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3233832A1 (en) | 2017-10-25 |
| EP3233832B1 (en) | 2019-11-20 |
| CA2971395A1 (en) | 2016-06-23 |
| US20160176843A1 (en) | 2016-06-23 |
| PL415073A1 (pl) | 2016-06-20 |
| AU2015363761B2 (en) | 2020-07-09 |
| ZA201704879B (en) | 2020-01-29 |
| US9440953B2 (en) | 2016-09-13 |
| CN107428720B (zh) | 2020-06-30 |
| US20160368894A1 (en) | 2016-12-22 |
| CN107428720A (zh) | 2017-12-01 |
| WO2016099311A1 (en) | 2016-06-23 |
| WO2016099311A4 (en) | 2016-09-09 |
| AU2015363761A1 (en) | 2017-07-20 |
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