PL3240895T3 - Kompozycje i sposoby dla glikozylacji białek - Google Patents

Kompozycje i sposoby dla glikozylacji białek

Info

Publication number
PL3240895T3
PL3240895T3 PL15822948T PL15822948T PL3240895T3 PL 3240895 T3 PL3240895 T3 PL 3240895T3 PL 15822948 T PL15822948 T PL 15822948T PL 15822948 T PL15822948 T PL 15822948T PL 3240895 T3 PL3240895 T3 PL 3240895T3
Authority
PL
Poland
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
PL15822948T
Other languages
English (en)
Inventor
Jurgen Haas
Julian Ihssen
Michael Thomas KOWARIK
Torsten Franz SCHWEDE
Linda Christiane THÖNY-MEYER
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of PL3240895T3 publication Critical patent/PL3240895T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL15822948T 2014-12-30 2015-12-24 Kompozycje i sposoby dla glikozylacji białek PL3240895T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462097975P 2014-12-30 2014-12-30
US201462098071P 2014-12-30 2014-12-30
PCT/EP2015/081229 WO2016107818A1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation
EP15822948.4A EP3240895B1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Publications (1)

Publication Number Publication Date
PL3240895T3 true PL3240895T3 (pl) 2022-05-02

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15822948T PL3240895T3 (pl) 2014-12-30 2015-12-24 Kompozycje i sposoby dla glikozylacji białek

Country Status (18)

Country Link
US (3) US10150952B2 (pl)
EP (2) EP4043561A1 (pl)
JP (1) JP6850724B2 (pl)
CN (1) CN107614679A (pl)
BE (1) BE1022998B1 (pl)
BR (1) BR112017014031B1 (pl)
CA (1) CA2971653C (pl)
CY (1) CY1125392T1 (pl)
DK (1) DK3240895T3 (pl)
ES (1) ES2907211T3 (pl)
HR (1) HRP20220500T1 (pl)
HU (1) HUE057726T2 (pl)
LT (1) LT3240895T (pl)
MX (1) MX389093B (pl)
PL (1) PL3240895T3 (pl)
PT (1) PT3240895T (pl)
SI (1) SI3240895T1 (pl)
WO (2) WO2016107818A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201807924T4 (tr) 2013-01-17 2018-06-21 Arsanis Biosciences Gmbh MDR e. koli spesifik antikor.
JP6276427B2 (ja) 2014-02-24 2018-02-07 グリコヴァキシン アーゲー 新規の多糖及びその使用
DK3240895T3 (da) 2014-12-30 2022-04-11 Glaxosmithkline Biologicals Sa Sammensætninger og fremgangsmåder til proteinglykosylering
JP6764872B2 (ja) 2015-02-26 2020-10-07 ヴァックスニューモ エルエルシーVaxnewmo Llc アシネトバクター(Acinetobacter)O−オリゴサッカリルトランスフェラーゼおよびその使用
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
CA3103474A1 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
CA3124312A1 (en) 2018-12-21 2020-06-25 Vaxnewmo Llc O-linked glycosylation recognition motifs
WO2020191082A1 (en) 2019-03-18 2020-09-24 Janssen Pharmaceuticals, Inc. Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
EA202192392A1 (ru) * 2019-03-18 2022-02-09 Янссен Фармасьютикалз, Инк. Способы получения биоконъюгатов полисахаридных о-антигенов e.coli, их композиции и способы их применения
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
PL4010467T3 (pl) * 2019-08-09 2024-08-05 Glaxosmithkline Biologicals Sa Zmutowane enzymy oligosacharylotransferazy pglb
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
PH12023550020A1 (en) 2020-09-17 2024-03-11 Janssen Pharmaceuticals Inc Multivalent vaccine compositions and uses thereof
WO2022171679A2 (en) * 2021-02-11 2022-08-18 Glaxosmithkline Biologicals Sa Protein
CN117222427A (zh) 2021-04-01 2023-12-12 杨森制药公司 大肠杆菌o18生物缀合物的生产
WO2023118033A1 (en) 2021-12-22 2023-06-29 Glaxosmithkline Biologicals Sa Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1888761T3 (da) * 2005-05-11 2010-11-01 Eth Zuerich Rekombinante N-glycosylerede proteiner fra prokaryote celler
US8999668B2 (en) * 2008-01-03 2015-04-07 Cornell Research Foundation, Inc. Glycosylated protein expression in prokaryotes
LT2257307T (lt) * 2008-02-20 2018-08-10 Glaxosmithkline Biologicals S.A. Biokonjugatai, gauti iš rekombinantinių n-glikozilintų baltymų iš prokariotinių ląstelių
CN102724997B (zh) * 2009-11-19 2016-09-21 格林考瓦因有限公司 在原核细胞中产生免疫原性多糖的生物合成系统
JP6339366B2 (ja) 2010-05-06 2018-06-06 グリコヴァキシン アーゲー 莢膜グラム陽性菌のバイオコンジュゲートワクチン
HK1202896A1 (en) * 2011-11-04 2015-10-09 康奈尔大学 A prokaryote-based cell-free system for the synthesis of glycoproteins
CA2923957C (en) * 2013-01-18 2021-08-31 London School Of Hygiene And Tropical Medicine Glycosylation method
DK3240895T3 (da) 2014-12-30 2022-04-11 Glaxosmithkline Biologicals Sa Sammensætninger og fremgangsmåder til proteinglykosylering
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
US10577592B2 (en) 2020-03-03
BE1022998B1 (fr) 2016-10-28
US11015177B2 (en) 2021-05-25
MX389093B (es) 2025-03-20
EP3240895B1 (en) 2022-01-26
BE1022998A1 (fr) 2016-10-28
JP6850724B2 (ja) 2021-03-31
CA2971653A1 (en) 2016-07-07
CA2971653C (en) 2024-06-11
HRP20220500T1 (hr) 2022-06-10
CY1125392T1 (el) 2024-02-16
BR112017014031A2 (pt) 2018-01-16
EP4043561A1 (en) 2022-08-17
SI3240895T1 (sl) 2022-04-29
PT3240895T (pt) 2022-03-02
DK3240895T3 (da) 2022-04-11
US20180002679A1 (en) 2018-01-04
HUE057726T2 (hu) 2022-06-28
WO2016107819A1 (en) 2016-07-07
US10150952B2 (en) 2018-12-11
CN107614679A (zh) 2018-01-19
MX2017008817A (es) 2017-10-24
LT3240895T (lt) 2022-04-11
US20190078064A1 (en) 2019-03-14
EP3240895A1 (en) 2017-11-08
ES2907211T3 (es) 2022-04-22
BR112017014031B1 (pt) 2023-11-07
JP2018500912A (ja) 2018-01-18
WO2016107818A8 (en) 2017-08-31
US20200181586A1 (en) 2020-06-11
WO2016107818A1 (en) 2016-07-07

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