DK3240895T3 - Sammensætninger og fremgangsmåder til proteinglykosylering - Google Patents

Sammensætninger og fremgangsmåder til proteinglykosylering Download PDF

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Publication number
DK3240895T3
DK3240895T3 DK15822948.4T DK15822948T DK3240895T3 DK 3240895 T3 DK3240895 T3 DK 3240895T3 DK 15822948 T DK15822948 T DK 15822948T DK 3240895 T3 DK3240895 T3 DK 3240895T3
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DK
Denmark
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
DK15822948.4T
Other languages
English (en)
Inventor
Jurgen Haas
Julian Ihssen
Michael Thomas Kowarik
Torsten Franz Schwede
Linda Christiane Thöny-Meyer
Original Assignee
Glaxosmithkline Biologicals Sa
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Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Application granted granted Critical
Publication of DK3240895T3 publication Critical patent/DK3240895T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK15822948.4T 2014-12-30 2015-12-24 Sammensætninger og fremgangsmåder til proteinglykosylering DK3240895T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462098071P 2014-12-30 2014-12-30
US201462097975P 2014-12-30 2014-12-30
PCT/EP2015/081229 WO2016107818A1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Publications (1)

Publication Number Publication Date
DK3240895T3 true DK3240895T3 (da) 2022-04-11

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15822948.4T DK3240895T3 (da) 2014-12-30 2015-12-24 Sammensætninger og fremgangsmåder til proteinglykosylering

Country Status (18)

Country Link
US (3) US10150952B2 (da)
EP (2) EP3240895B1 (da)
JP (1) JP6850724B2 (da)
CN (1) CN107614679B (da)
BE (1) BE1022998B1 (da)
BR (1) BR112017014031B1 (da)
CA (1) CA2971653C (da)
CY (1) CY1125392T1 (da)
DK (1) DK3240895T3 (da)
ES (1) ES2907211T3 (da)
HR (1) HRP20220500T1 (da)
HU (1) HUE057726T2 (da)
LT (1) LT3240895T (da)
MX (1) MX389093B (da)
PL (1) PL3240895T3 (da)
PT (1) PT3240895T (da)
SI (1) SI3240895T1 (da)
WO (2) WO2016107819A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE038915T2 (hu) 2013-01-17 2018-12-28 Arsanis Biosciences Gmbh MDR E. colira fajlagos antitest
NZ723328A (en) 2014-02-24 2018-01-26 Glycovaxyn Ag Compositions comprising e. coli o25b antigen, uses thereof and methods of manufacture
SI3240895T1 (sl) 2014-12-30 2022-04-29 Glaxosmithkline Biologicals S.A. Sestavki in postopki za glikozilacijo proteinov
US10265391B2 (en) 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
ES3051337T3 (en) 2018-06-16 2025-12-26 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs
IL286467B2 (en) 2019-03-18 2026-02-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of polysaccharides E. coli o-antigen, preparations thereof and methods for using them
CR20210522A (es) 2019-03-18 2021-12-17 Janssen Pharmaceuticals Inc Bioconjugados de antígenos–polisacáridos de e. coli, métodos de producción y métodos de utilización de los mismos
EP3770269A1 (en) * 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
MX2022001606A (es) * 2019-08-09 2022-03-11 Glaxosmithkline Biologicals Sa Enzimas de oligosacariltransferasa pglb mutada.
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
PE20231385A1 (es) 2020-09-17 2023-09-12 Janssen Pharmaceuticals Inc Composiciones de vacunas multivalentes y usos de las mismas
US12680087B2 (en) 2021-02-11 2026-07-14 Glaxosmithkline Biologicals Sa Mutated PGLB oligosaccharyltransferase enzymes
MX2023011697A (es) 2021-04-01 2023-10-19 Janssen Pharmaceuticals Inc Produccion de bioconjugados o18 de e. coli.
EP4452308A1 (en) 2021-12-22 2024-10-30 GlaxoSmithKline Biologicals S.A. Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2535084T3 (es) * 2005-05-11 2015-05-05 Eth Zurich Proteínas N-glicosiladas recombinantes procedentes de células procariotas
WO2009089154A2 (en) * 2008-01-03 2009-07-16 Cornell Research Foundation, Inc. Glycosylated protein expression in prokaryotes
SI2257307T1 (sl) * 2008-02-20 2018-09-28 Glaxosmithkline Biologicals S.A. Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic
NO2501406T3 (da) * 2009-11-19 2018-05-19
WO2011138361A1 (en) 2010-05-06 2011-11-10 Glycovaxyn Capsular gram-positive bacteria bioconjugate vaccines
IN2014CN04076A (da) * 2011-11-04 2015-10-23 Univ Cornell
US9931392B2 (en) * 2013-01-18 2018-04-03 London School Of Hygiene And Tropical Medicine Glycosylation method
SI3240895T1 (sl) 2014-12-30 2022-04-29 Glaxosmithkline Biologicals S.A. Sestavki in postopki za glikozilacijo proteinov
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
PL3240895T3 (pl) 2022-05-02
US10150952B2 (en) 2018-12-11
JP6850724B2 (ja) 2021-03-31
US20190078064A1 (en) 2019-03-14
SI3240895T1 (sl) 2022-04-29
WO2016107818A8 (en) 2017-08-31
ES2907211T3 (es) 2022-04-22
MX2017008817A (es) 2017-10-24
EP3240895B1 (en) 2022-01-26
EP3240895A1 (en) 2017-11-08
CA2971653A1 (en) 2016-07-07
CY1125392T1 (el) 2024-02-16
CA2971653C (en) 2024-06-11
JP2018500912A (ja) 2018-01-18
EP4043561A1 (en) 2022-08-17
US20180002679A1 (en) 2018-01-04
WO2016107819A1 (en) 2016-07-07
CN107614679B (zh) 2026-04-07
CN107614679A (zh) 2018-01-19
US20200181586A1 (en) 2020-06-11
WO2016107818A1 (en) 2016-07-07
PT3240895T (pt) 2022-03-02
BE1022998B1 (fr) 2016-10-28
US10577592B2 (en) 2020-03-03
BE1022998A1 (fr) 2016-10-28
BR112017014031A2 (pt) 2018-01-16
BR112017014031B1 (pt) 2023-11-07
HUE057726T2 (hu) 2022-06-28
LT3240895T (lt) 2022-04-11
US11015177B2 (en) 2021-05-25
MX389093B (es) 2025-03-20
HRP20220500T1 (hr) 2022-06-10

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