PL3279202T3 - Kryształ 3,5-dipodstawionego związku benzenoalkinylowego - Google Patents

Kryształ 3,5-dipodstawionego związku benzenoalkinylowego

Info

Publication number
PL3279202T3
PL3279202T3 PL16773207T PL16773207T PL3279202T3 PL 3279202 T3 PL3279202 T3 PL 3279202T3 PL 16773207 T PL16773207 T PL 16773207T PL 16773207 T PL16773207 T PL 16773207T PL 3279202 T3 PL3279202 T3 PL 3279202T3
Authority
PL
Poland
Prior art keywords
crystal
disubstituted benzene
alkynyl compound
benzene alkynyl
compound
Prior art date
Application number
PL16773207T
Other languages
English (en)
Inventor
Kosuke Egami
Original Assignee
Taiho Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co., Ltd. filed Critical Taiho Pharmaceutical Co., Ltd.
Publication of PL3279202T3 publication Critical patent/PL3279202T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C30CRYSTAL GROWTH
    • C30BSINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54Organic compounds
    • C30B29/58Macromolecular compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Metallurgy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL16773207T 2015-03-31 2016-03-31 Kryształ 3,5-dipodstawionego związku benzenoalkinylowego PL3279202T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015070927 2015-03-31
PCT/JP2016/060844 WO2016159327A1 (ja) 2015-03-31 2016-03-31 3,5-二置換ベンゼンアルキニル化合物の結晶
EP16773207.2A EP3279202B1 (en) 2015-03-31 2016-03-31 Crystal of 3,5-disubstituted benzene alkynyl compound

Publications (1)

Publication Number Publication Date
PL3279202T3 true PL3279202T3 (pl) 2020-12-28

Family

ID=57006122

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16773207T PL3279202T3 (pl) 2015-03-31 2016-03-31 Kryształ 3,5-dipodstawionego związku benzenoalkinylowego

Country Status (18)

Country Link
US (1) US10434103B2 (pl)
EP (1) EP3279202B1 (pl)
JP (2) JP6190079B2 (pl)
KR (1) KR101917557B1 (pl)
CN (2) CN111393446B (pl)
AU (1) AU2016240841C1 (pl)
CA (1) CA2980888C (pl)
DK (1) DK3279202T3 (pl)
ES (1) ES2812785T3 (pl)
HU (1) HUE051074T2 (pl)
MX (1) MX373612B (pl)
MY (1) MY196077A (pl)
PH (1) PH12017501690B1 (pl)
PL (1) PL3279202T3 (pl)
PT (1) PT3279202T (pl)
RU (1) RU2672563C1 (pl)
SG (1) SG11201707384YA (pl)
WO (1) WO2016159327A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201907147T4 (tr) 2013-07-18 2019-06-21 Taiho Pharmaceutical Co Ltd Fgfr inhibitörünün aralıklı uygulanmasına yönelik anti-tümör ilaç.
JP6084292B2 (ja) 2013-07-18 2017-02-22 大鵬薬品工業株式会社 Fgfr阻害剤耐性癌の治療薬
PL3279202T3 (pl) 2015-03-31 2020-12-28 Taiho Pharmaceutical Co., Ltd. Kryształ 3,5-dipodstawionego związku benzenoalkinylowego
US11883404B2 (en) 2016-03-04 2024-01-30 Taiho Pharmaceuticals Co., Ltd. Preparation and composition for treatment of malignant tumors
JP7085985B2 (ja) 2016-03-04 2022-06-17 大鵬薬品工業株式会社 悪性腫瘍治療用製剤及び組成物
JP6918204B2 (ja) 2018-03-19 2021-08-11 大鵬薬品工業株式会社 アルキル硫酸ナトリウムを含む医薬組成物
AU2018448845B2 (en) 2018-11-09 2022-03-24 Taiho Pharmaceutical Co., Ltd. Method for producing dimethoxybenzene compound
WO2020096042A1 (ja) 2018-11-09 2020-05-14 大鵬薬品工業株式会社 ジメトキシベンゼン化合物の製造方法
US20220023300A1 (en) * 2018-11-26 2022-01-27 Taiho Pharmaceutical Co., Ltd. Therapeutic and prophylactic method for tumor treatable with endocrine therapy by combined use of fibroblast growth factor receptor inhibitor with endocrine therapy
WO2020170355A1 (ja) * 2019-02-20 2020-08-27 大鵬薬品工業株式会社 Fgfr1変異腫瘍の治療方法
CA3139161A1 (en) * 2019-05-17 2020-11-26 Kinnate Biopharma Inc. Inhibitors of fibroblast growth factor receptor kinases
WO2021247969A1 (en) 2020-06-05 2021-12-09 Kinnate Biopharma Inc. Inhibitors of fibroblast growth factor receptor kinases

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1931676B1 (en) 2005-10-06 2011-11-16 Schering Corporation Pyrazolopyrimidines as protein kinase inhibitors
PL1971601T3 (pl) 2005-11-15 2010-03-31 Array Biopharma Inc Pochodne N4-fenylo-chinazolino-4-aminy i związki pokrewne jako inhibitory receptorowych kinaz tyrozynowych ErbB typu I do leczenia chorób cechujących się nadmierną proliferacją komórek
TW200738725A (en) 2006-01-25 2007-10-16 Osi Pharm Inc Unsaturated mTOR inhibitors
EP1939197A1 (en) 2006-12-22 2008-07-02 Schwarz Pharma Ag 8-ethinylxanthine derivatives as selective A2A receptor antagonists
CA2874756C (en) 2007-03-28 2018-05-29 Pharmacyclics, Inc. Inhibitors of bruton's tyrosine kinase
AU2009261683A1 (en) 2008-06-19 2009-12-23 Astrazeneca Ab Pyrazole compounds 436
GB0819105D0 (en) 2008-10-17 2008-11-26 Chroma Therapeutics Ltd Pyrrolo-pyrimidine compounds
ES2458872T3 (es) 2009-04-30 2014-05-07 Novartis Ag Derivados de imidazol y su uso como moduladores de quinasas dependientes de ciclina
KR101483215B1 (ko) 2010-01-29 2015-01-16 한미약품 주식회사 단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체
WO2011115937A1 (en) 2010-03-14 2011-09-22 The Translational Genomics Research Institute Methods of determining susceptibility of tumors to tyrosine kinase inhibitors
DE102011015188A1 (de) 2010-03-29 2011-09-29 Herbert Kannegiesser Gmbh Verfahren zur Nassbehandlung, insbesondere zum Reinigen, von Gegenständen
MX342405B (es) 2010-06-03 2016-09-28 Pharmacyclics Inc El uso de inhibidores de la tirosina quinasa de bruton (btk).
SG193327A1 (en) 2011-04-06 2013-10-30 Taiho Pharmaceutical Co Ltd Novel imidazo-oxazine compound or salt thereof
EP2657233B1 (en) * 2012-01-19 2014-08-27 Taiho Pharmaceutical Co., Ltd. 3,5-disubstituted alkynylbenzene compound and salt thereof
ES2580530T3 (es) * 2012-02-23 2016-08-24 Taiho Pharmaceutical Co., Ltd. Compuesto con anillo fusionado de quinolilpirrolopirimidilo o sal del mismo
CN103570725B (zh) 2012-08-01 2017-03-22 中国科学院上海药物研究所 哌嗪并三唑类化合物及其制备方法和用途
JP2016510751A (ja) 2013-03-06 2016-04-11 ジェネンテック, インコーポレイテッド 抗がん剤耐性を治療及び予防する方法
PL2986610T4 (pl) 2013-04-19 2019-06-28 Incyte Holdings Corporation Bicykliczne heterocykle jako inhibitory FGFR
JP6084292B2 (ja) * 2013-07-18 2017-02-22 大鵬薬品工業株式会社 Fgfr阻害剤耐性癌の治療薬
TR201907147T4 (tr) * 2013-07-18 2019-06-21 Taiho Pharmaceutical Co Ltd Fgfr inhibitörünün aralıklı uygulanmasına yönelik anti-tümör ilaç.
BR112016021206B1 (pt) 2014-04-25 2022-07-12 Chugai Seiyaku Kabushiki Kaisha Composição farmacêutica, contendo composto tetracíclico em dose elevada e seu método de produção
PL3279202T3 (pl) 2015-03-31 2020-12-28 Taiho Pharmaceutical Co., Ltd. Kryształ 3,5-dipodstawionego związku benzenoalkinylowego
JP7085985B2 (ja) 2016-03-04 2022-06-17 大鵬薬品工業株式会社 悪性腫瘍治療用製剤及び組成物

Also Published As

Publication number Publication date
JPWO2016159327A1 (ja) 2017-04-27
MX2017012568A (es) 2018-01-25
HUE051074T2 (hu) 2021-03-01
HK1246297A1 (zh) 2018-09-07
CA2980888C (en) 2018-03-06
CN107406455A (zh) 2017-11-28
WO2016159327A1 (ja) 2016-10-06
PH12017501690B1 (en) 2023-12-06
EP3279202A4 (en) 2018-08-22
AU2016240841B2 (en) 2018-02-01
KR101917557B1 (ko) 2018-11-09
AU2016240841A1 (en) 2017-10-05
DK3279202T3 (da) 2020-08-17
EP3279202A1 (en) 2018-02-07
ES2812785T3 (es) 2021-03-18
PT3279202T (pt) 2020-08-31
CN107406455B (zh) 2020-05-12
EP3279202B1 (en) 2020-06-24
US10434103B2 (en) 2019-10-08
JP6190079B2 (ja) 2017-08-30
SG11201707384YA (en) 2017-10-30
CN111393446A (zh) 2020-07-10
MY196077A (en) 2023-03-13
CN111393446B (zh) 2022-12-20
PH12017501690A1 (en) 2018-03-19
CA2980888A1 (en) 2016-10-06
AU2016240841C1 (en) 2018-05-17
RU2672563C1 (ru) 2018-11-16
JP2017193581A (ja) 2017-10-26
KR20170132251A (ko) 2017-12-01
BR112017019809A2 (pt) 2018-05-29
MX373612B (es) 2020-05-07
US20180110782A1 (en) 2018-04-26

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