PL3283506T3 - Sposób wytwarzania aneksyny v - Google Patents
Sposób wytwarzania aneksyny vInfo
- Publication number
- PL3283506T3 PL3283506T3 PL16766559T PL16766559T PL3283506T3 PL 3283506 T3 PL3283506 T3 PL 3283506T3 PL 16766559 T PL16766559 T PL 16766559T PL 16766559 T PL16766559 T PL 16766559T PL 3283506 T3 PL3283506 T3 PL 3283506T3
- Authority
- PL
- Poland
- Prior art keywords
- annexin
- manufacture
- Prior art date
Links
- 102000000412 Annexin Human genes 0.000 title 1
- 108050008874 Annexin Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Analytical Chemistry (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Marine Sciences & Fisheries (AREA)
- Transplantation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1516516.0A GB2542391A (en) | 2015-09-17 | 2015-09-17 | Process of manufacture |
| EP16766559.5A EP3283506B1 (en) | 2015-09-17 | 2016-09-16 | Process of manufacture of annexin v |
| PCT/EP2016/072066 WO2017046391A2 (en) | 2015-09-17 | 2016-09-16 | Process of manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3283506T3 true PL3283506T3 (pl) | 2019-02-28 |
Family
ID=54544424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16766559T PL3283506T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
| PL18182321.2T PL3453721T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18182321.2T PL3453721T3 (pl) | 2015-09-17 | 2016-09-16 | Sposób wytwarzania aneksyny v |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11773134B2 (pl) |
| EP (3) | EP3453721B1 (pl) |
| JP (5) | JP6689371B2 (pl) |
| CN (3) | CN108137662B (pl) |
| CA (2) | CA3036298A1 (pl) |
| DK (2) | DK3283506T3 (pl) |
| ES (2) | ES2699155T3 (pl) |
| GB (1) | GB2542391A (pl) |
| HK (1) | HK1251580B (pl) |
| PL (2) | PL3283506T3 (pl) |
| WO (1) | WO2017046391A2 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2542391A (en) * | 2015-09-17 | 2017-03-22 | Annexin Pharmaceuticals Ab | Process of manufacture |
| EP3495376A1 (en) * | 2017-12-05 | 2019-06-12 | ChromaCon AG | Improved chromatographic process for cell culture harvest |
| EP3560945A1 (en) * | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
| WO2020045290A1 (ja) * | 2018-08-31 | 2020-03-05 | 株式会社カネカ | 抗体または抗体様分子の精製方法 |
| TWI871300B (zh) * | 2019-01-28 | 2025-02-01 | 美商安進公司 | 藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程 |
| CN110669141A (zh) * | 2019-09-29 | 2020-01-10 | 杭州联科生物技术股份有限公司 | 一种别藻蓝蛋白(APC)与Annexin V蛋白偶联方法 |
| TW202146042A (zh) * | 2020-03-06 | 2021-12-16 | 瑞典商阿斯特捷利康公司 | 用於治療動脈和靜脈血栓形成的協同且靶向的組成物 |
| CN111378005B (zh) * | 2020-04-03 | 2021-08-17 | 安徽环球基因科技有限公司 | 一种可调式纯化蛋白装置 |
| CN112057623A (zh) * | 2020-06-03 | 2020-12-11 | 江苏靶标生物医药研究所有限公司 | 一种磷脂酰丝氨酸在制备治疗炎症性肠病药物中的应用 |
| JP2024515311A (ja) * | 2021-04-25 | 2024-04-08 | 上海薩美細胞技術有限公司 | 肺損傷を治療するための薬物 |
| TW202323269A (zh) * | 2021-12-08 | 2023-06-16 | 荷蘭商菲林公司 | 方法 |
| CN114539383B (zh) * | 2022-02-24 | 2024-03-26 | 南京大学 | 一种人源膜联蛋白人源膜联蛋白a5突变体二聚体的晶体结构的制备方法和应用 |
| GB202207263D0 (en) * | 2022-05-18 | 2022-06-29 | Annexin Pharmaceuticals Ab | Therapeutic compositions |
| CN118001376A (zh) * | 2023-02-27 | 2024-05-10 | 上海萨美细胞技术有限公司 | 膜联蛋白a5在生发、育发、护发、防脱发以及治疗脱发中的用途和相关产品和药物组合物 |
| CN121194795A (zh) * | 2023-05-18 | 2025-12-23 | 安尼欣制药有限公司 | 膜联蛋白a5蛋白质与抗vegf药剂作为组合疗法用于治疗黄斑水肿或视网膜静脉阻塞 |
| WO2025086968A1 (zh) * | 2023-10-25 | 2025-05-01 | 上海萨美细胞技术有限公司 | 一种用于治疗肺纤维化的药物 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU601676B2 (en) | 1985-01-10 | 1990-09-20 | Biogen, Inc. | Dna sequences recombinant dna molecules and processes for producing human lipocorton-like polypeptides |
| DE3643182A1 (de) * | 1986-12-18 | 1988-06-30 | Behringwerke Ag | Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4 |
| DE3939169A1 (de) * | 1989-11-27 | 1991-05-29 | Behringwerke Ag | Verfahren zur reinigung von lipocortinen |
| DE4003773A1 (de) * | 1990-02-08 | 1991-08-14 | Behringwerke Ag | Verfahren zur reinigung von lipocortinen |
| DE4012341A1 (de) * | 1990-04-18 | 1991-10-24 | Behringwerke Ag | Monoklonale antikoerper gegen pp4, verfahren zu ihrer herstellung und ihre verwendung |
| US5968477A (en) * | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
| JP2000239299A (ja) | 1999-02-15 | 2000-09-05 | Snow Brand Milk Prod Co Ltd | 新規蛋白質及びその製造方法 |
| US6492327B2 (en) * | 2000-12-19 | 2002-12-10 | Sulzer Biologics Inc. | Isolation of purified TGF- β1 and TGF -β2 from bone tissue |
| GB0101300D0 (en) * | 2001-01-18 | 2001-02-28 | Univ Cambridge Tech | Primordial germ cell genes |
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2015
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2016
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