PL3321252T3 - Nowy związek, który specyficznie wiąże się z receptorem AMPA - Google Patents

Nowy związek, który specyficznie wiąże się z receptorem AMPA

Info

Publication number
PL3321252T3
PL3321252T3 PL16821400T PL16821400T PL3321252T3 PL 3321252 T3 PL3321252 T3 PL 3321252T3 PL 16821400 T PL16821400 T PL 16821400T PL 16821400 T PL16821400 T PL 16821400T PL 3321252 T3 PL3321252 T3 PL 3321252T3
Authority
PL
Poland
Prior art keywords
specifically binds
novel compound
ampa receptor
ampa
receptor
Prior art date
Application number
PL16821400T
Other languages
English (en)
Inventor
Takuya Takahashi
Tomoyuki Miyazaki
Tetsuya Suhara
Makoto Higuchi
Meiei CHO
Original Assignee
Public University Corporation Yokohama City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Public University Corporation Yokohama City University filed Critical Public University Corporation Yokohama City University
Publication of PL3321252T3 publication Critical patent/PL3321252T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/49—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
PL16821400T 2015-07-06 2016-07-05 Nowy związek, który specyficznie wiąże się z receptorem AMPA PL3321252T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015135124 2015-07-06
PCT/JP2016/069896 WO2017006931A1 (ja) 2015-07-06 2016-07-05 Ampa受容体に特異的に結合する新規化合物
EP16821400.5A EP3321252B1 (en) 2015-07-06 2016-07-05 Novel compound that specifically binds to ampa receptor

Publications (1)

Publication Number Publication Date
PL3321252T3 true PL3321252T3 (pl) 2021-04-06

Family

ID=57685631

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16821400T PL3321252T3 (pl) 2015-07-06 2016-07-05 Nowy związek, który specyficznie wiąże się z receptorem AMPA

Country Status (17)

Country Link
US (1) US10335503B2 (pl)
EP (1) EP3321252B1 (pl)
JP (1) JP6425817B2 (pl)
KR (1) KR101997699B1 (pl)
CN (1) CN107922328B (pl)
AU (1) AU2016289031C1 (pl)
BR (1) BR112017028639B1 (pl)
CA (1) CA2991400C (pl)
DK (1) DK3321252T3 (pl)
ES (1) ES2829638T3 (pl)
IL (1) IL256735B (pl)
MX (1) MX386015B (pl)
PL (1) PL3321252T3 (pl)
RU (1) RU2705595C2 (pl)
SG (1) SG11201800071PA (pl)
TW (1) TWI675820B (pl)
WO (1) WO2017006931A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11224668B2 (en) * 2016-02-29 2022-01-18 Neurovation Labs, Inc. Compositions and methods to detect GluA1 in brain and to identify the presence of GluA1-mediated PTSD
JP2020045285A (ja) * 2017-01-11 2020-03-26 公立大学法人横浜市立大学 Ampa受容体に関連する疾患の予防及び/又は治療剤
JP6241974B1 (ja) * 2017-01-11 2017-12-06 公立大学法人横浜市立大学 霊長類生体の脳内ampa受容体のイメージング方法、プログラム、及びスクリーニング方法
US11439715B2 (en) 2017-08-28 2022-09-13 Neurovation Labs, Inc. Compositions and methods to detect GLUA1 in brain and to identify the presence of GLUA1-mediated post-traumatic stress disorder and other neurological disorders
CN110483343B (zh) * 2019-09-03 2021-08-27 泰州职业技术学院 一种新型的磺酰氯衍生物、其制备方法及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189211A (en) 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
EP0811375B1 (en) * 1995-02-21 2001-01-03 Nippon Suisan Kaisha, Ltd. Glutamic acid receptor agonist
UA67749C2 (uk) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
WO2001096308A1 (en) 2000-06-12 2001-12-20 Eisai Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof
FR2854634B1 (fr) 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
MX2011002884A (es) * 2008-09-17 2011-04-21 Suven Life Sciences Ltd Compuestos de aril-sulfonamida-amina y su uso como ligandos de 5-ht6.
JP5455396B2 (ja) 2009-02-27 2014-03-26 知之 西崎 プロテインホスファターゼ−1阻害剤
US20120230914A1 (en) 2009-07-03 2012-09-13 Riken Labeling compound for pet
JP2016522786A (ja) * 2013-04-04 2016-08-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 [11c]及び[18f]標識化1,3−ジフェニルー5−(ピリミジン−2−イル)−ピリジン−2(1h)−オン誘導体並びにampa受容体のpetイメージングのためのそれらの使用
EP3062827A1 (en) 2013-10-31 2016-09-07 Bristol-Myers Squibb Company Radioligands for imaging the lpa-1 receptor

Also Published As

Publication number Publication date
SG11201800071PA (en) 2018-02-27
BR112017028639A2 (pt) 2018-09-11
JPWO2017006931A1 (ja) 2018-06-21
US20180200391A1 (en) 2018-07-19
CN107922328A (zh) 2018-04-17
IL256735A (en) 2018-03-29
EP3321252A4 (en) 2019-03-13
BR112017028639B1 (pt) 2023-03-21
TWI675820B (zh) 2019-11-01
EP3321252A1 (en) 2018-05-16
MX2018000242A (es) 2018-03-08
TW201706242A (zh) 2017-02-16
CA2991400A1 (en) 2017-01-12
JP6425817B2 (ja) 2018-11-21
CN107922328B (zh) 2020-05-19
AU2016289031C1 (en) 2019-10-17
KR20180025951A (ko) 2018-03-09
RU2705595C2 (ru) 2019-11-11
US10335503B2 (en) 2019-07-02
AU2016289031A1 (en) 2018-01-25
AU2016289031B2 (en) 2019-07-18
HK1250230A1 (zh) 2018-12-07
ES2829638T3 (es) 2021-06-01
IL256735B (en) 2021-02-28
RU2018104555A (ru) 2019-08-06
MX386015B (es) 2025-03-18
WO2017006931A1 (ja) 2017-01-12
DK3321252T3 (da) 2020-11-16
RU2018104555A3 (pl) 2019-08-06
EP3321252B1 (en) 2020-10-21
KR101997699B1 (ko) 2019-07-08
CA2991400C (en) 2020-05-12

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