FR2854634B1 - Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2854634B1
FR2854634B1 FR0305448A FR0305448A FR2854634B1 FR 2854634 B1 FR2854634 B1 FR 2854634B1 FR 0305448 A FR0305448 A FR 0305448A FR 0305448 A FR0305448 A FR 0305448A FR 2854634 B1 FR2854634 B1 FR 2854634B1
Authority
FR
France
Prior art keywords
novel
preparation
pharmaceutical compositions
compositions containing
thiadiazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0305448A
Other languages
English (en)
Other versions
FR2854634A1 (fr
Inventor
Emmanuel Graindorge
Pierre Francotte
Stephane Boverie
Tullio Pascal De
Bernard Pirotte
Pierre Lestage
Laurence Danober
Pierre Renard
Daniel Henri Caignard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Priority to FR0305448A priority Critical patent/FR2854634B1/fr
Priority to UAA200511454A priority patent/UA80046C2/uk
Priority to MYPI20041647A priority patent/MY136694A/en
Priority to EP04742632A priority patent/EP1620441A1/fr
Priority to JP2006505830A priority patent/JP4461139B2/ja
Priority to PCT/FR2004/001070 priority patent/WO2004099217A1/fr
Priority to EA200501696A priority patent/EA009240B1/ru
Priority to CNB200480014886XA priority patent/CN100363368C/zh
Priority to HK06108870.2A priority patent/HK1088327B/xx
Priority to MXPA05011823A priority patent/MXPA05011823A/es
Priority to GEAP20049092A priority patent/GEP20084318B/en
Priority to ZA200508660A priority patent/ZA200508660B/en
Priority to NZ543214A priority patent/NZ543214A/en
Priority to KR1020057020817A priority patent/KR100741235B1/ko
Priority to US10/555,743 priority patent/US7476668B2/en
Priority to CA2524377A priority patent/CA2524377C/fr
Priority to AU2004236005A priority patent/AU2004236005B2/en
Priority to BRPI0410002-6A priority patent/BRPI0410002A/pt
Priority to ARP040101515A priority patent/AR044245A1/es
Publication of FR2854634A1 publication Critical patent/FR2854634A1/fr
Application granted granted Critical
Publication of FR2854634B1 publication Critical patent/FR2854634B1/fr
Priority to MA28567A priority patent/MA27732A1/fr
Priority to NO20055695A priority patent/NO20055695L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR0305448A 2003-05-05 2003-05-05 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2854634B1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0305448A FR2854634B1 (fr) 2003-05-05 2003-05-05 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UAA200511454A UA80046C2 (en) 2003-05-05 2004-04-05 Thiadiazine compounds, method for obtaning thereof and pharmaceutical composition containing them
MYPI20041647A MY136694A (en) 2003-05-05 2004-04-30 New thiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
US10/555,743 US7476668B2 (en) 2003-05-05 2004-05-04 Thiadiazine derivatives and use thereof as positive AMPA receptor modulators
PCT/FR2004/001070 WO2004099217A1 (fr) 2003-05-05 2004-05-04 Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa
EA200501696A EA009240B1 (ru) 2003-05-05 2004-05-04 Новые соединения тиадиазина, способ их получения и фармацевтические композиции, которые их содержат
CNB200480014886XA CN100363368C (zh) 2003-05-05 2004-05-04 噻二嗪衍生物及其用作正ampa受体调节剂的用途
HK06108870.2A HK1088327B (en) 2003-05-05 2004-05-04 Thiadiazine derivatives and use thereof as positive ampa receptor modulators
MXPA05011823A MXPA05011823A (es) 2003-05-05 2004-05-04 Derivados de tiadiazina y su uso como moduladores positivos de los receptores ampa.
GEAP20049092A GEP20084318B (en) 2003-05-05 2004-05-04 Thiadiazine derivatives and use thereof as positive ampa receptor modulators
EP04742632A EP1620441A1 (fr) 2003-05-05 2004-05-04 Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa
NZ543214A NZ543214A (en) 2003-05-05 2004-05-04 New thiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
KR1020057020817A KR100741235B1 (ko) 2003-05-05 2004-05-04 티아디아진 유도체 및 양성 ａｍｐａ 수용체조절인자로서의 이들의 용도
JP2006505830A JP4461139B2 (ja) 2003-05-05 2004-05-04 チアジアジン誘導体及びポジティブａｍｐａ受容体モジュレーターとしてのそれらの使用
CA2524377A CA2524377C (fr) 2003-05-05 2004-05-04 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2004236005A AU2004236005B2 (en) 2003-05-05 2004-05-04 Thiadiazine derivatives and use thereof as positive AMPA receptor modulators
BRPI0410002-6A BRPI0410002A (pt) 2003-05-05 2004-05-04 derivados de tiadiazina e sua utilização como modeladores positivos dos receptores ampa
ARP040101515A AR044245A1 (es) 2003-05-05 2004-05-04 Derivados de tiadiazina su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
ZA200508660A ZA200508660B (en) 2003-05-05 2004-05-04 Thiadiazine derivatives and use thereof as positive AMPA receptor modulators
MA28567A MA27732A1 (fr) 2003-05-05 2005-10-21 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
NO20055695A NO20055695L (no) 2003-05-05 2005-12-01 Tiadiazinforbindelser og anvendelse derav som positive AMPA-reseptormodulatorer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0305448A FR2854634B1 (fr) 2003-05-05 2003-05-05 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2854634A1 FR2854634A1 (fr) 2004-11-12
FR2854634B1 true FR2854634B1 (fr) 2005-07-08

Family

ID=33306157

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0305448A Expired - Fee Related FR2854634B1 (fr) 2003-05-05 2003-05-05 Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (20)

Country Link
US (1) US7476668B2 (fr)
EP (1) EP1620441A1 (fr)
JP (1) JP4461139B2 (fr)
KR (1) KR100741235B1 (fr)
CN (1) CN100363368C (fr)
AR (1) AR044245A1 (fr)
AU (1) AU2004236005B2 (fr)
BR (1) BRPI0410002A (fr)
CA (1) CA2524377C (fr)
EA (1) EA009240B1 (fr)
FR (1) FR2854634B1 (fr)
GE (1) GEP20084318B (fr)
MA (1) MA27732A1 (fr)
MX (1) MXPA05011823A (fr)
MY (1) MY136694A (fr)
NO (1) NO20055695L (fr)
NZ (1) NZ543214A (fr)
UA (1) UA80046C2 (fr)
WO (1) WO2004099217A1 (fr)
ZA (1) ZA200508660B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104958270A (zh) 2004-08-25 2015-10-07 伊森舍丽斯有限公司 钾atp通道开放剂的药物制剂及其应用
PL1968601T3 (pl) * 2006-01-05 2012-03-30 Essentialis Inc Sole związków otwierających kanały potasowe ATP i ich zastosowanie
US20110218190A1 (en) * 2008-11-10 2011-09-08 The Regents Of The University Of California Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction
SI2603513T1 (sl) 2010-08-10 2020-07-31 Takeda Pharmaceutical Company Limited Heterociklična spojina in njena uporaba kot pozitivni alosterični modulator receptorja AMPA
JP5901365B2 (ja) * 2012-03-12 2016-04-06 株式会社トクヤマ イミダート化合物の製造方法
BR112015031249A2 (pt) 2013-06-13 2017-07-25 Veroscience Llc método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica
DK3321252T3 (da) 2015-07-06 2020-11-16 Public Univ Corp Yokohama City Univ Ny forbindelse der specifikt binder til ampa-receptor
US20190112300A1 (en) 2016-03-29 2019-04-18 Arnold Stan Lippa Compositions And Methods For Treating Attention Deficit Disorders
JP6241974B1 (ja) 2017-01-11 2017-12-06 公立大学法人横浜市立大学 霊長類生体の脳内ａｍｐａ受容体のイメージング方法、プログラム、及びスクリーニング方法
US10680583B1 (en) * 2019-02-26 2020-06-09 Xilinx, Inc. Control circuit for and method of controlling an operation of an integrated circuit device
PL4031552T3 (pl) 2019-09-16 2025-03-17 Takeda Pharmaceutical Company Limited Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733409A (en) * 1969-05-20 1973-05-15 Schering Corp Method of treating hypertension using thieno (1,2,4) thiadiazines
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
EP1000066A1 (fr) * 1997-07-16 2000-05-17 Novo Nordisk A/S Derives de 1,2,4-thiadiazine fusionnee, leur preparation et utilisation
CA2320354A1 (fr) * 1998-02-18 1999-08-26 Neurosearch A/S Nouveaux composes et leur utilisation comme modulateurs positifs du recepteur ampa
FR2801587B1 (fr) * 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
CA2524377A1 (fr) 2004-11-18
UA80046C2 (en) 2007-08-10
BRPI0410002A (pt) 2006-04-25
EA200501696A1 (ru) 2006-06-30
US20070004709A1 (en) 2007-01-04
KR20060006830A (ko) 2006-01-19
MXPA05011823A (es) 2006-05-25
WO2004099217A1 (fr) 2004-11-18
FR2854634A1 (fr) 2004-11-12
US7476668B2 (en) 2009-01-13
CN1798750A (zh) 2006-07-05
EP1620441A1 (fr) 2006-02-01
EA009240B1 (ru) 2007-12-28
AU2004236005B2 (en) 2010-01-21
AU2004236005A1 (en) 2004-11-18
GEP20084318B (en) 2008-03-10
CN100363368C (zh) 2008-01-23
MA27732A1 (fr) 2006-01-02
MY136694A (en) 2008-11-28
JP2006525292A (ja) 2006-11-09
NO20055695L (no) 2005-12-01
NZ543214A (en) 2009-02-28
AR044245A1 (es) 2005-09-07
KR100741235B1 (ko) 2007-07-19
CA2524377C (fr) 2010-08-24
HK1088327A1 (en) 2006-11-03
ZA200508660B (en) 2007-01-31
JP4461139B2 (ja) 2010-05-12

Similar Documents

Publication Publication Date Title
FR2824825B1 (fr) Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2816938B1 (fr) Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
FR2866647B1 (fr) Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2846657B1 (fr) Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2846656B1 (fr) Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2872164B1 (fr) Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR2803848B1 (fr) Nouveaux derives de benzenesulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2883876B1 (fr) Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2833956B1 (fr) Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877338B1 (fr) Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2885616B1 (fr) Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
MA27092A1 (fr) Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2825091B1 (fr) Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2833950B1 (fr) Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2812291B1 (fr) Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2853649B1 (fr) Nouveaux derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2827287B1 (fr) Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2881138B1 (fr) Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856064B1 (fr) Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2859723B1 (fr) Nouveaux derives de benzoindoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
MA27407A1 (fr) Nouveaux derives de 2,3-dihydro-4(1h)-pyridinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2827284B1 (fr) Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2885615B1 (fr) Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2841243B1 (fr) Nouveaux derives de 3-(4-oxo-4h-chromen-2yl)-(1h)-quinolein- 4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20130131